In this new, revised edition of his landmark book, Montagu compels us to reevaluate the way we think about growth and development, in all its phases, throughout life. Humans are designed to grow and develop their childlike qualities, and not to become the ossified adults prescribed by society. Montagu demonstrates how our culture, schools, and families are in conspiracy against such childlike traits as the need to love, to learn, to wonder, to know, to explore, to think, to experiment, to be imaginative, creative and curious, to sing, dance, or play. He also reveals the many links between physical and mental aging and tells how to prevent psychosclerosis, the hardening of the mind, so that we can die young--as late as possible. The best statement ever written on the most important, neglected theme of human life and evolution. "Stephen Jay Gould, Harvard University"

In this new, revised edition of his landmark book, Montagu compels us to reevaluate the way we think about growth and development, in all its phases, throughout life. Humans are designed to grow and develop their childlike qualities, and not to become the ossified adults prescribed by society. Montagu demonstrates how our culture, schools, and families are in conspiracy against such childlike traits as the need to love, to learn, to wonder, to know, to explore, to think, to experiment, to be imaginative, creative and curious, to sing, dance, or play. He also reveals the many links between physical and mental aging and tells how to prevent psychosclerosis, the hardening of the mind, so that we can die young--as late as possible.

This short volume selects and describes the main facts about the 'facts of life' and discusses their significance to man. It is only natural that it includes much information gleaned from mammalian reproductive patterns. It was their investigation that historically gave the clues to understanding what happens in human reproduction.

This book represents an attempt to review the most recent knowledge concerning basic processes occurring in the most important female reproductive organ -- the ovaries and their regulators. The most important processes (ovarian cyclic changes and oogenesis), as well as their extracellular (hormones and growth factors) and intracellular (protein kinases, transcription factors, small RNAs) regulators are described. Data concerning processes or substances well described in previous reviews are summarised here in a short form with references to corresponding reviews.

In this book, the authors present current research in the study of ovulation detection, its signs, symptoms and outcomes. Topics discussed in this compilation include the importance of up and down regulation of receptors for FSH, progesterone and GnRH in the ovary, endometrium and lymphocytes in correcting various ovulatory disorders and achieving live deliveries; polycystic ovary syndrome and implications in metabolic disorders; cancer risk of drugs for ovarian stimulation; alternatives to laparoscopic ovarian drilling for ovulation induction in clomiphene resistent women with polycystic ovary syndrome; reproductive outcomes and obesity; ovarian hyperstimulation syndrome and a focus on neurovascular complications; and new methods for ovulation detection.

In this book, the authors present current research in the study of the anatomy, physiology and pathology of the testes. Topics discussed in this compilation include the roles and regulatory mechanism of proton pumping V-ATPase in spermatozoa and epididymis physiology; oxidative stress as a converging mechanism of testicular damage; the pathophysiology of the testis after ischemia reperfusion injury; beta-actin implications in the seminiferous tubule; heat stress damage in mammalian testis; and the effect of plasticisers on testis and Sertoli cell functions.

This book represents an attempt to review the most recent knowledge concerning basic processes occurring in the most important female reproductive organ -- ovary and their regulators. The most important processes (ovarian cyclic changes and oogenesis), as well as their extracellular (hormones and growth factors) and intracellular (protein kinases, transcription factors, small RNAs) regulators are described. Data concerning processes or substances well described in previous reviews are summarised here in a short form with references to corresponding reviews.

Spermatozoa is the basic human male germ cell. This gametocyte plays an important role in fertilisation. In the past five years, new improvements in diagnosis have allowed us to assess male fertility potential with a new perspective studying with demonstrated role in sperm physiology. Furthermore, it is demonstrated that infertile men have high levels of sperm DNA damages and a small percentage of spermatozoa from fertile men also possess detectable levels of DNA damage. This book examines several of the factors that may be involved in sperm chromatin and DNA anomalies, including intra and extra testicular factors. Furthermore, sperm capacitation is a complex physiological process that involves biochemical, biophysical, molecular and metabolic modifications of all sperm domains. Some important events related to the capacitation process of sperm is examined as well. The biological role of the proteasome during sperm capacitation and the acrosome reaction and its relationship with protein phosphorylation and dephosphorylation during these processes is explored as well. Other chapters in this book highlight the pivotal role of transmission electron microscopy (TEM) analysis in the diagnosis of human sperm pathologies, the barrier methods currently available to men for regulating their fertility, a discussion of the current understanding of gene transfer to the testis, a new perspectives for the study of mycoplasmal and chlamydial infections of human spermatozoa and a discussion of the present current knowledge on the mechanisms, molecules and cell signalling involved in sperm activating ability.

The Female Reproductive System chart presents an overview of the structure and function of female reproductive anatomy. The primary image illustrates the overall structure, including the ovary, uterine tube and uterus. Diagrams show the process of the menstrual cycle and ovulation. Heavy cover stock with protective varnish for durability.

Growth hormone (GH) or somatotropin (STH) is a protein hormone that stimulates growth and cell reproduction in humans and other animals. It is a 191-amino acid; single chain polypeptide hormone which is synthesised, stored, and secreted by the somatotroph cells within the lateral wings of the anterior pituitary gland. HGH promotes growth in children and plays an important role in adult metabolism. The body secretes the hormone, in decreasing amounts, throughout our lifetimes. The amount of hormone in the body can be measured by levels of IGF-1 (Insulin Growth Factor). Growth hormone has a profound effect on all the cells of the body, more than any other hormone because it is the cell generator. This book presents the latest research in the field.

Human beings the world over are eager to form social bonds, and suffer grievously when these bonds are disrupted. Social connections contribute to our sense of meaning and feelings of vitality, on the one hand, and - at times - to our anguish and despair on the other. It is not surprising that the mechanisms underlying human connections have long interested researchers from diverse disciplines including social psychology, developmental psychology, communication studies, sociology, and neuroscience. Yet there is too little dialogue among these disciplines and too little integration of insights and findings. This fifth book in the Herzliya Series on Personality and Social Psychology aims to rectify that situation by providing a comprehensive survey of cutting-edge theory and research on social connections. The volume contains 21 chapters organised into four main sections: Brain (focusing on the neural underpinnings of social connections and the hormonal processes that contribute to forming connections) Infancy and Development (focusing especially on child-parent relationships) Dyadic Relationship (focusing especially on romantic and marital relationships) Group (considering both evolutionary and physiological bases of group processes) The integrative perspectives presented here are thought-provoking reading for anyone interested in the social nature of the human mind.

What happens when a baby is born with "ambiguous" genitalia or a combination of "male" and "female" body parts? Clinicians and parents in these situations are confronted with complicated questions such as whether a girl can have XY chromosomes, or whether some penises are "too small" for a male sex assignment. Since the 1950s, standard treatment has involved determining a sex for these infants and performing surgery to normalize the infant's genitalia. Over the past decade intersex advocates have mounted unprecedented challenges to treatment, offering alternative perspectives about the meaning and appropriate medical response to intersexuality and driving the field of those who treat intersex conditions into a deep crisis. Katrina Karkazis offers a nuanced, compassionate picture of these charged issues in "Fixing Sex," the first book to examine contemporary controversies over the medical management of intersexuality in the United States from the multiple perspectives of those most intimately involved.

Drawing extensively on interviews with adults with intersex conditions, parents, and physicians, Karkazis moves beyond the heated rhetoric to reveal the complex reality of how intersexuality is understood, treated, and experienced today. As she unravels the historical, technological, social, and political forces that have culminated in debates surrounding intersexuality, Karkazis exposes the contentious disagreements among theorists, physicians, intersex adults, activists, and parents--and all that those debates imply about gender and the changing landscape of intersex management. She argues that by viewing intersexuality exclusively through a narrow medical lens we avoid much more difficult questions. Do gender atypical bodies require treatment? Should physicians intervene to control the "sex" of the body? As this illuminating book reveals, debates over treatment for intersexuality force reassessment of the seemingly natural connections between gender, biology, and the body.

This comics anthology delves deeply into the messy and often taboo subject of human reproduction. Featuring work by luminaries such as Carol Tyler, Alison Bechdel, and Joyce Farmer, Graphic Reproduction is an illustrated challenge to dominant cultural narratives about conception, pregnancy, and childbirth. The comics here expose the contradictions, complexities, and confluences around diverse individual experiences of the entire reproductive process, from trying to conceive to child loss and childbirth. Jenell Johnson's introduction situates comics about reproduction within the growing field of graphic medicine and reveals how they provide a discursive forum in which concepts can be explored and presented as uncertainties rather than as part of a prescribed or expected narrative. Through comics such as Lyn Chevley's groundbreaking "Abortion Eve," Bethany Doane's "Pushing Back: A Home Birth Story," Leah Hayes's "Not Funny Ha-Ha," and "Losing Thomas & Ella: A Father's Story," by Marcus B. Weaver-Hightower, the collection explores a myriad of reproductive experiences and perspectives. The result is a provocative, multifaceted portrait of one of the most basic and complicated of all human experiences, one that can be hilarious and heartbreaking. Featuring work by well-known comics artists as well as exciting new voices, this incisive collection is an important and timely resource for understanding how reproduction intersects with sociocultural issues. The afterword and a section of discussion exercises and questions make it a perfect teaching tool.

The placenta is a fetomaternal organ provided by nature to aid development of the growing embryo by facilitating gas and nutrient exchange between the mother and foetus and by helping to maintain fetomaternal tolerance. Aside from playing an age-old and essential role in foetal development, placental tissues have also attracted the interest of clinical scientists due to their potential utility as a therapeutic agent. This book provides an overview of the clinical applications which have been described for placental tissue or are currently applied, as well as a summary of the most recent results obtained in pre-clinical studies, which present promising perspectives for the future clinical application of these cells. The trophoblast, a cell type of the placenta, is also outlined in this book, as well as its function in the placenta during pregnancy and its role in developmental processes and gynecological diseases. In addition, pregnancy-specific glycoproteins (PSGs) are secreted proteins which are produced by the rodent and primate placenta, and play a critical role in pregnancy success. This book summarises and analyses the data on structure and function of PSGs known to date. Relatively recent data of PSG-derived biologically active peptides are also described. Other chapters examine placental functions and their role in predicting development and disease in infancy and childhood, and the role of insulin like growth factors (IFGs) in normal and abnormal placental and foetal development during pregnancy.

Experts in the fields of energy metabolism, aging and oxidative stress provide an integrated view of how mechanisms involved in regulating energy metabolism are linked to fundamental processes of aging including cellular stress resistance and free radical production.

During evolution signal transduction pathways and organ systems have been optimised for the efficient seeking, ingestion, storing and using of energy. These signalling pathways play prominent roles in lifespan determination with insulin and related signalling pathways being prime examples. The authors consider how lifespan and healthspan can be extended through knowledge of energy metabolism with the experimental model of dietary restriction being one example. The information in this volume of ACAG will foster novel approaches and experiments for further understanding the roles of energy metabolism in aging and disease.

FROM THE FOREWORD by James Birren:

In Health, Illness, and Optimal Aging: Biological and Psychosocial Perspectives, Carolyn M. Aldwin and Diane F. Gilmer undertake the challenging task of assembling an objective and holistic picture of human aging. The authors provide comprehensive, multidisciplinary coverage of the physical aspects of aging, including age-related changes and disease-related processes, the demography of the aging population, theories of aging, and the promotion of optimal aging. In addition, the book covers the psychosocial aspects of aging, including mental health, stress and coping, spirituality, and care giving in later years.

• Integrated. Discusses both the biological aspects and psychosocial factors of aging, thus providing integrated coverage of information from the fields of biology, psychology, and the social sciences.
• Comprehensive. Covers every part of the aging process including the physical effect on the different systems of the human body, quality of life, social support, and health promotion programs.
• Pedagogical. Examples in each chapter enhance students' understanding of real-life situations, and methodological issues help students become more critical consumers of research and data.

Health, Illness and Optimal Aging is recommended for researchers seeking an overview of health psychology and aging, as well as undergraduate and graduate students taking classes in the social, behavioral, and health sciences. This text is also valuable for practitioners working with the elderly in fields such as nursing, social work, occupational and physical therapy, day-care and nursing home administration, psychology, and rehabilitation.

Blank and Merrick argue that medical advances, changing social values, and novel legal cases challenging conventional notions of reproductive rights, raising questions and creating difficult policy dilemmas.

This volume focuses on the conflicts surrounding reproduction and reproductive rights. Restricted access to abortion, rights of surrogate and biological mothers, the right to control fertility, fetal and embryo research, and a pregnant woman's duty to avoid risk are among the timely issues explored in this book. Conflicts in the maternal-fetal relationship, such as court-ordered intervention, maternal substance abuse, and workplace hazards are also covered.

Natural childbirth and rooming in; artificial insemination and in vitro fertilisation; sterilisation and abortion: women's health and reproduction went through a revolution in the twentieth century as scientific advances confronted ethical and political dilemmas. In New Zealand, the major site for this revolution was National Women's Hospital. Established in Auckland in 1946, with a purpose-built building that opened in 1964, National Women's was the home of medical breakthroughs by Sir William (Bill) Liley and Sir Graham (Mont) Liggins; of the Lawson quintuplets and the 'glamorous gynaecologists'; and of scandals surrounding the 'unfortunate experiment' and the neonatal chest physiotherapy inquiry. In this major history, Linda Bryder traces the rise and fall of National Women's over half a century in order to tell a wider story of reproductive health. She uses the varying perspectives of doctors, nurses, midwives, consumer groups and patients to show how together their dialogue shaped the nature of motherhood and women's health in twentieth-century New Zealand.

This fully-revised new edition of the best-selling Equine Clinical Medicine, Surgery and Reproduction is supported by over 1800 illustrations of the highest quality: colour photographs, diagnostic images including MRI and CT, and diagrams. System-based, the chapters introduce each individual system with precise information on the relevant basic anatomy and physiology, standard clinical examination techniques and useful differential diagnostic aids. This is followed by diseases and disorders that are pertinent to that system, grouped together either anatomically or based on presenting clinical signs. Each condition is described using consistent headings: definition/overview, etiology and pathophysiology, clinical presentation, diagnosis, differential diagnoses, management/treatment, and prognosis. Additional chapters deal with the foal and wounds. New to the second edition: - All chapters are updated throughout - Additional chapters on the axial musculoskeletal system (neck, back and pelvis) and muscle diseases and problems - A whole new section on soft tissue injuries of the foot - More information on diagnostic tests including over-ground endoscopy, chest and liver ultrasonography, head CT, and foot MRI - Material on equine dentistry, neurology, endocrine system, the foal, and the liver has been considerably expanded - All illustrations and photographs have been reviewed and many replaced with higher quality images. The focus throughout remains on providing clinically relevant information required for practical case management, plus sufficient background on causes and disease processes to enable readers to understand the conditions and the rationale for diagnostic and treatment options. An international group of respected clinicians have come together under the editorship of Dr Graham Munroe to create a textbook that will be of lasting value as a teaching and training resource for equine clinical teachers and their students in veterinary medicine and related equine courses, as well as a ready reference for non-specialist mixed or equine clinical practitioners

The new, fully updated edition of this successful book, brings together the combined experience of a leading dedicated unit over 25 years in delivering expert medical and surgical care to children with DSD (Disorders|Differences of Sex Development) in a holistic environment. It documents the most recent advances in the molecular biology and embryology of sex development, and describes each variation in detail. The main focus of the book is on patients with variations with their anatomy and hormone function. New chapters describe the developments in the field in terms of definitions and incidence, the mental health of DSD patients and discuss the perspectives of patients families and support groups. The clinical presentation and approach to diagnosis are described both for babies and for children presenting later in childhood or at adolescence. The chapters on management highlight all the latest knowledge and include the shared wisdom of the authors on current controversies, such as the timing of surgical treatment. Finally, the authors describe their short-, medium-, and long-term outcomes, which demonstrate the strengths of holistic team management.

Inspired by Carlos Beyer's 50 years of pioneering research and influence on his students and colleagues, Behavioral Neuroendocrinology builds upon Beyer's fundamental discoveries and concepts as well as their widespread implications. It presents original research and reviews on mechanisms - genomic and non-genomic - of steroid and protein hormone action; the role of steroid metabolism, especially aromatization, protein phosphorylation, and neurotransmitter action in mediating reproductive behavior and sexual differentiation; and brain and spinal cord mechanisms in sexual behavior and analgesia. This book presents a rich diversity of topics - lactation, maternal behavior, pheromone action, chronobiology, allodynia, angiogenesis, prostate physiology, sexual motivation, and specific brain systems, including vomeronasal system, cerebellum, preoptic area, hypothalamus, and spinal cord. This book brings together, in one source, an international "family" of researchers whose work has evolved in diverse but related ways from a seminal set of discoveries and concepts in behavioral neuroendocrinology.

Rationalization is concerned with making the most effective use of the resources available. In many places where this process is taking place it is plagued with public opposition and misunderstanding. Hitherto rationalization in the acute care sector has primarily been concerned with closing sites closing beds moving beds between services and moving beds from one site to another. This book discusses the need for rationalization in the context of health service reforms and future strategy. It considers recent changes in the health service the case for rationalization health care needs the role of public relations the future of the acute care hospital site and facilities appraisal and the costs of rationalization. The text is essential reading for managers and clinicians involved in acute care services non-executive members of boards and trusts and students of health services management.

Here is a major new work on human infancy written by one of the country's leading developmental psychologists and two distinguished colleagues. At its core is the long-awaited report of the authors' six-year study of infant day care. Important in its own right, this experiment becomes the occasion for a wide-ranging discussion of cognitive and emotional processes in infancy, of the effects of early experience on later growth, and of the deep-seated cultural and historical assumptions that underlie our views of human development. For those concerned with social policy, the book provides the best empirical assessment now available of the effects of group care on the psychological well-being of infants. It also supplies a blueprint for quality daycare that may well stand as a model for future nurseries. For those interested in the course of cognitive and emotional development, the book provides rich information about the major growth functions that characterize human infancy. It also outlines an explanation of these growth functions that links changes in emotional behavior to the maturation of underlying cognitive processes in a new and provocative way. And for everyone interested in human nature, the book of offers a controversial thesis about the discontinuity of psychological growth that challenges some of our most fundamental assumptions about the nature of individual development. For this paperback edition, the statistical summary has been removed from the appendix to shorten the work and make it even more appealing to the general reader.

Covering the subject at both the fundamental and applied levels, Follicular Growth, Ovulation and Fertilization highlights contraception, infertility management, environment, aging, and reproductive processes. Written by experts in their respective fields, the scientific contributions cover the basic aspects of reproductive biology with a special focus on fertility control and treatment of infertility. The book highlights the latest developments in reproductive biology and their connection to the emerging techniques in reproductive medicine including andrology, reproductive biology, and ovarian function.