FUNDAMENTALS OF BIOSTATISTICS leads you through the methods, techniques, and computations of statistics necessary for success in the medical field. Every new concept is developed systematically through completely worked out examples from current medical research problems.

A comprehensive, user-friendly guide to marriage and family therapy that takes a holistic view to look at people within the context of their environment. Family Therapy helps students understand the process of shifting from an individual psychology paradigm to a cybernetic or systems paradigm. The text is divided into three sections: "The Systemic Framework," "The Practice of Family Therapy," and "The Systemic Practitioner," and it includes historical information, current developments, and ongoing debates. Various family and developmental theories are examined. The family therapy models considered include psychodynamic, natural systems, experiential, structural, communications, strategic, behavioral/cognitive, and several post-modern approaches. Assessment, intervention, training and supervision, research, and epistemological challenges are discussed within the context of practice. Learning Goals Upon completing this book readers will be able to: Describe and compare various family therapy models Discuss practical applications for different family and developmental theories Review and assess unique family systems to determine the appropriate family therapy model Understand how concepts with the same name differ in meaning at different levels (i.e. 1 st order versus 2 nd order cybernetics)

The discipline of disaster medicine is the study and collaborative application of various health sciences towards the prevention of, preparation for, response to and recovery from health problems arising from a disaster.

Because disasters can strike anywhere in the world and can have devastating effects on the community, it is vitally important that the different agencies, government departments and medical disciplines work together to draw up adequate mitigation plans. It is also crucial that each agency is aware of its responsibilities and understands the chain of command in a disaster situation.

In a clear and concise manner Disaster Medicine covers all the critical aspects necessary to deal with any type of man-made or natural disaster.

Learn the skills and strategies you need to be an effective and empathic helper with EFFECTIVE HELPING: INTERVIEWING AND COUNSELING TECHNIQUES, Eighth Edition. Today's helpers must have a wider, more diverse range of knowledge and skills than ever before-including an understanding of culturally diverse human behavior and development, the process of change, the power of contemporary forces, and sound theories and methods of helping and communicating. This clear, applied, and respected book will help you master the skills of interviewing and relationship building to prepare you for the reality of what it's like to be a helper. It's also a resource you'll want to hold onto well into your career.

A midwife is responsible for recording the progress of labour on a partograph or partogram. The partograph helps caregivers detect whether labour is progressing normally or not, indicates when augmentation of labour is appropriate and assists in recognising potential problems before they occur. Each title covers one important topic, and has been written by a specialist in that field. The series follows a consistent format and covers issues such as key ethical and legal considerations, relevant legislation, case studies, and practical applications. These concise, accessible texts will be suitable for accreditation when continuing professional development becomes a requirement

Occupational Safety and Health (OSH) in the workplace is not only a strategic priority in terms of moral or social responsibility, it is also an obligation regulated and governed by law. A well-designed manufacturing process (the operations system) must be both productive and safe, without potential physical, emotional and mental health risks. OSH management has become a very complex multi-functional science within operations management and total quality management (TQM). It focuses on a non-legalistic approach whereby the organisational culture fosters spontaneous OSH and a high quality of work life. This is done by using a TQM approach, based on a functional TQM model.

Since its first publication in 1996, Marie Muller's Nursing Dynamics has become firmly established as an essential resource for nursing courses. This fifth edition addresses the latest challenges nursing professionals face and expands the focus to include all managers in healthcare service management. Nursing and midwifery educators who relied on earlier editions of this work will find that their discipline is still the core of this book, with the management aspects broadened to include general healthcare dynamics. Subjects range from professional regulation to governance, decision making, financial management, quality management and continuing professional development. New features include the introduction of digital elements including online student–lecturer support material and a digital portfolio of evidence to enrich the content. The practical application of principles has been formalised with the inclusion of case studies and assignments at the end of each chapter. These exercises follow a Head-Heart-Hands model, covering the knowledge behind the principle, the ethical and "duty of care" considerations, and the hands-on application.

Employing a syndromic approach to palliative care for nurses in South Africa, this guidebook aims to reduce suffering in people with life threatening conditions. Equipping nurses, health care professionals, and medical students with the knowledge, skills, and attitudes necessary to enable a palliative approach to their daily clinical practices, this resource addresses special topics of health such as HIV/AIDS, cancer, and honing communication skills for talking with the bereaved. Additional topics of discussion include the legal and ethical issues in palliative care in South Africa, organizing palliative care in the public sector, and the pathophysiology of pain.

Juta's counselling handbook for healthcare professionals will help health professionals apply practical counselling principles to a range of healthcare situations in a South African context. Given the shortage of qualified counsellors and other mental health professionals in South Africa, healthcare workers without specialist knowledge are often called upon to counsel clients. There is no one-size-fits-all solution for many of the issues discussed. However, we hope that this handbook will enable readers to design an appropriate counselling intervention that is helpful to clients and their families.

Study guide that develops concepts and skills for first-year subjects; Practice for exam questions with answers included; Tutor memo provides explanations to common questions; Step-by-step demonstrations; Highlighter focuses attention on key areas.

Understanding Psychopathology: South African Perspectives 3e provides a solid introduction to the study of mental disorders that incorporates socio-cultural, psychological and biomedical dimensions. It refers to criteria from both the Diagnostic and Statistical Manual of Mental Disorders (DSM–5) and the International Classifications of Diseases (ICD–10) to describe and define mental disorders. It also looks at the ICD–11, and how this new version has been harmonised with the DSM–5.

The third edition of this book, previously published as Abnormal Psychology revised second edition, presents South African debates and data to ensure that it is relevant to the local context. In addition, research from the rest of Africa has been integrated into the book to show how other countries in our region are grappling with topical issues.

This book is aimed at second- and third-year students following courses in Psychopathology or Abnormal Psychology as part of a Bachelor of Arts or Bachelor of Social Sciences degree at Universities. It has been written by academics and practitioners from across South Africa.

Health and Safety: Risk Management is the clearest and most comprehensive book on risk management available today. This newly revised fifth edition takes into account new developments in legislation, standards and good practice. ISO 45001, the international health and safety management system standard, is given comprehensive treatment, and the latest ISO 9004 and ISO 19011 have also been addressed. The book is divided into four main parts. Part 1.1 begins with a basic introduction to the techniques of health and safety risk management and continues with a description of ISO 45001. Part 1.2 covers basic human factors including how the sense organs work and the psychology of the individual. Part 2.1 deals with more advanced techniques of risk management including advanced incident investigation, audit and risk assessment, and Part 2.2 covers a range of advanced human factors topics including human error and decision making. This authoritative treatment of health and safety risk management is essential reading for both students working towards degrees, diplomas and postgraduate or vocational qualifications, and experienced health and safety professionals, who will find it invaluable as a reference.

Global public health has improved vastly during the past 25 years, and especially in the survival of infants and young children. However, many of these children, particularly in Africa, continue to live in poverty and in unhealthy, unsupportive environments, and will not be able to meet their developmental potential. In other words, they will survive but not thrive. The UN’s Sustainable Development Goals (SDGs) stress sustainable development, not just survival and disease reduction, and the Global Strategy for Women’s, Children’s and Adolescents’ Health proposes a Survive (end preventable deaths), Thrive (ensure health and wellbeing) and Transform (expand enabling environments) agenda. For children to thrive they must make good developmental progress from birth until the end of adolescence.

Addressing the social determinants of developmental problems, this volume offers a broad, contextualised understanding of the factors that impact on children and adolescents in Africa. Unlike other works on the subject it is Africa-wide in its scope, with case studies in Ethiopia, Kenya, Malawi, Nigeria, Rwanda and South Africa. Covering mental health as well as physical and social development, it looks at policies and practice, culture and priorities for research, identifying challenges and proposing solutions.

Recommended for academics, students and practitioners in psychology, including developmental psychology, child clinical psychology, developmental psychopathology, psychiatry, human ecology, and in schools of education. It will also be of interest to nurses and paediatricians, health workers and those interested in early childhood development.

Res Ipsa Loquitur and Medical Negligence: A Comparative Survey analyses the application of the doctrine of res ipsa loquitur ('it speaks for itself') to medical negligence cases. The book aims to establish conclusively that the approach of the South African courts, that the doctrine should never find application in medical negligence cases, is untenable and out of touch with modern approaches adopted in other countries. Constitutional principles such as procedural equality, access to courts, access to health care, access to information, post-constitutional legislation, medical ethics and policy considerations are also discussed.

The book further provides a theoretical and practical legal framework for the application of the doctrine to medical negligence cases in South Africa in future. The authors argue for the application of the doctrine, not only in medical negligence cases, but also to related legal procedures that follow a medical accident such as medical inquests, criminal prosecutions and disciplinary inquiries instituted by the Health Professions Council of South Africa.

Res Ipsa Loquitur and Medical Negligence includes a comprehensive comparison of the practical application of the doctrine to medical negligence cases in South Africa, England and the United States of America.

Safeguarding economic prosperity, whilst protecting human health and the environment, is at the forefront of scientific and public interest. This book provides a practical and balanced view on toxicology, control, risk assessment and risk management, addressing the interplay between science and public health policy. This fully revised and updated new edition provides a detailed analysis on chemical and by-product exposure, how they enter the body and the suitability of imposed safety limits. New chapters on dose, with particular emphasis on children and vulnerable subpopulations, reproductive and developmental toxicants and toxicity testing are included. With updated and comprehensive coverage of international developments of risk management and safety, this will have broad appeal to researchers and professionals involved in chemical safety and regulation as well as the general reader interested in environmental pollution and public health.

The fourth edition of ACSM's Exercise Management for Persons With Chronic Diseases and Disabilities reveals common ground between medical and exercise professionals, creating a more collaborative approach to patient care. Developed by the American College of Sports Medicine (ACSM) with contributions from a specialized team of experts, this text presents a framework for optimizing patients' and clients' functionality by keeping them physically active. Featuring new content on common comorbid conditions, this edition is streamlined and updated to better suit chronic populations. This fourth edition of ACSM's Exercise Management for Persons With Chronic Diseases and Disabilities outlines why exercise is significant in the treatment and prevention of disease, advises medical and exercise professionals in considering proper exercise prescription protocols, and provides evidence-informed guidance on devising individualized exercise programs. Major advancements and features of the fourth edition include the following: * Current evidence on exercise management for persons with multiple conditions, providing guidance on working with these common yet complex populations * A refocused goal of using physical activity to optimize patients' and clients' functionality and participation in life activities rather than only to treat and prevent disease * Specific content to help physicians prescribe physical activity and exercise to patients for promotion of health, well-being, and longevity * Reorganization of case studies into one streamlined chapter along with commentary from the senior editor to encourage critical thinking and recognize the unique needs of each patient The case studies in the text are real-life scenarios that help professionals and clinicians combine scientific knowledge with experience to find appropriate solutions for each individual. Commentary on the case studies from the senior editor illustrates when improvisation may be appropriate and where further research is needed. Tables are highlighted throughout the text to help readers quickly reference important clinical information. Evidence-informed guidelines, suggested websites, and additional readings further encourage practical use of information and identify further learning opportunities. For instructors, an ancillary PowerPoint presentation package aids in classroom discussion. The critical element that distinguishes the fourth edition of ACSM's Exercise Management for Persons With Chronic Diseases and Disabilities is its unifying mission to incorporate physical activity and exercise in both disease treatment and prevention. Its emphasis on assisting people with multiple conditions, which is ever present in health care today, moves beyond primary and secondary prevention to focus on how patients and clients can be kept physically active and functionally fit.

ACSM's Resource Manual for Guidelines for Exercise Testing and Prescription was created as a complement to ACSM's Guidelines for Exercise Testing and Prescription and elaborates on all major aspects of preventative rehabilitation and fitness programs and the major position stands of the ACSM. The 7th edition provides information necessary to address the knowledge, skills, and abilities set forth in the new edition of Guidelines, and explains the science behind the exercise testing and prescription. ACSM's Resource Manual is a comprehensive resource for those working in the fitness and clinical exercise fields, as well as those in academic training. Highlights include: * An expanded behavior change section with the tools needed to motivate people to begin exercise and then adhere to a program * Content reflects the most recent research findings in the field as well as ACSM position stands

Its accessibility, practicality, and comprehensiveness have long made the Introductory Textbook of Psychiatry, Seventh Edition, an essential resource for students of psychiatry. Learners will find all of those same qualities in this companion study guide.

With a format that replicates what medical students and psychiatric residents might encounter in specialty certification exams, this guide is organized along the lines of DSM-5(R) and includes detailed questions on diagnosis, interviewing and assessment, all DSM-5(R) disorders, up-to-date treatment information, and more.

Each multiple-choice question is linked to specific pages in the Textbook for ease of reference and includes plausible distractors. The answer guide includes explanations not only of the correct responses but also of why the other options are incorrect.

Beyond mere rote memorization, the Study Guide to Introductory Psychiatry is designed to help learners truly assimilate and deeply encode the information in the Introductory Textbook of Psychiatry, Seventh Edition, so that they can recall it when it matters most--when speaking with the patients they treat.

The 28th edition of Bailey & Love’s Short Practice of Surgery is the leading surgical resource for medical students and surgeons in training. It encompasses the basic principles of careful history taking, observation, deductive reasoning, technical knowledge and post-operative patient care to ensure safe surgical practice.

Key features

Relevant - the content matches both undergraduate and post-graduate curriculae

Readable – features summary boxes of core knowledge throughout the text. The consistent layout and style of tables, graphics, and diagrams aids easy understanding of key concepts. Also includes algorithms to assist the reader in understanding patient care pathways

Current- highlights where major developments in surgical practice have occurred or are likely to transform surgical practice in the next decade

Contemporary – includes expanded coverage of paediatric surgery and of transplant surgery. Emphasizes the importance of the multidisciplinary team approach, together with patient engagement in difficult decision making

Authoritative – every chapter has been revised by expert authors, and the most up to date content has been included in a familiar format

Digital Resources – Readers can access extra content via the dedicated Bailey and Love website which includes Questions and Answers, Expanded Content, Videos, Author interviews and more

Bailey & Love’s Short Practice of Surgery 28th edition continues to provide the essential knowledge required for surgical training. It remains a familiar friend, venerated by generations of medical students as well as surgeons young and old as a rite of passage and a repository of the core learning needed for clinical practice.

Table of Contents

Preface

Contributors

Part 1: Basic Principles

Metabolic response to injury　

Iain D. Anderson

Shock and blood transfusion

Karim Brohi

Wounds, healing, tissue repair

Sarah L. Benyon and Kai Yuen Wong

Tissue engineering and regeneration

Andrew W. McCaskie & Liam M. Grover

Surgical infection

H.Paul Redmond & Zeeshan Razzaq

Tropical infections and infestations

Sanjay De Bakshi & Pawanindra Lal

Basic surgical skills

Mark Coleman & Joshua Franklyn

Diagnostic imaging

Mathew Mattson, Muaaze Z. Ahmad and Niall Power

Gastrointestinal Endoscopy

Philip Woodland and Dr Rao

Principles of minimal access surgery

Ara Darzi and Leanne Harling

Tissue and molecular diagnosis　

Roger Feakins & Rondell P. Graham

Principles of oncology

Grant Stewart & Tim Eisen

Surgical audit and research

Thomas Pinkney and Birgit Whitman

Ethics and law in surgical practice

Robert Wheeler

Human factors, patient safety and quality improvement

Kenneth Mealy & Deborah McNamara

Global Health and surgery

Christopher B.D. Lavy and Nobhojit Roy

Part 2: General Paediatrics

General Paediatrics

Anthony D.Lander

18. Neonatal Surgery

Anna-May Long

19. Trauma in children

Elizabeth Gavens

20. Paediatric Urology

Mohan Gundeti

Part 3: PERIOPERATIVE CARE

21. Pre-operative care including the high-risk patient

Amy J. Thomas

22. Day case surgery

Kim Russon

23. Anaesthesia and pain relief

Vivek Mehta and Serene H.-L.Chang

24. Postoperative care, including perioperative optimisation

Anand Sardesai and Anita Balakrishnan

25. Nutrition and fluid therapy

Anita Balakrishnan

Part 4: Trauma

26. Introduction to trauma　

Robert C.Handley and Peter Giannoudis

27. Early assessment and management of severe trauma

Chris Moran and Dan Deakin

28. Traumatic brain injury

Harry Bulstrode and Antonio Belli

29. Torso & pelvic trauma　

Kenneth D. Boffard and Mansoor Ali Khan

30. The neck and spine

John R. Crawford and Douglas Hay

31. Maxillofacial trauma

Peter Brennan and Rabindra Singh

32. Extremity trauma

Lee Van Rensburg & Jaikirty Rawal

33. Disaster surgery

Mamoon Rashid

34. Conflict Surgery

Jon Clasper and Phill Pearce

Part 5: Elective Orthopaedics

35. History taking and clinical examination in musculoskeletal disease

Stephen McDonnell and Hemant G Pandit

36. Sports medicine and sports injuries

Peter J. Millet and Joseph J. Ruzbarsky

37. The spine

Brian Freeman and Christopher B.D. Lavy

38. The upper limb

David Limb and Samuel R. Vollans

39. The hip

Vikas Khanduja and Karadi H Sunil Kumar

40. The knee

Wasim S. Khan and Andrew J. Porteous

41. The foot and ankle

Bob Sharp

42. Musculoskeletal tumours

W. Paul Cool and Craig Gerrand

43. Infection of the bones and joints

Martin A. McNally

44. Paediatric orthopaedics

Deborah Eastwood

Part 6: Skin, Plastic & Reconstructive

45. Skin and subcutaneous tissue

Adam R. Greenbaum

46. Burns

John E. Greenwood and Lindsay Damkat-Thomas

47. Plastic and reconstructive surgery

James K.-K.Chan and Marc C.Swan

Part 7: Head and Neck

48. Cranial neurosurgery

Liam Gray and Harry Bulstrode

49.The eye and orbit

Keith R. Martin

50. Developmental abnormalities of the face mouth and jaws: cleft lip and palate

David A Koppel and Mark F Devlin

51.The ear, nose and sinuses

Iain F. Hathorn and Alex Bennett

52.The pharynx, larynx and neck

Vinidh Paleri and Anusha Balasubramanian

53.Oral Cavity

Andrew Schache and John Edward O'Connell

54. Disorders of the salivary glands

Prathamesh S Pai, Deepa Nair,and Manish D.Mair

Part 8: Endocrine and Breast

55.The thyroid gland

Richard M. Adamson & Iain Nixon

56.The parathyroid glands

Ruth S. Prichard

57. The adrenal glands and other abdominalendocrine disorders

Michael Stechman and David Scott-Coombes

58. The breast

Anurag Srivastava, Suhani Suhani, and Anita Dhar

Part 9: Cardiothoracic

59.Cardiac surgery

Mustafa Zakkar

60.The thorax

Carol Tan and Ian Hunt

Part 10: Vascular

61.Arterial disorders

Robert S.M.Davies

62. Venous and lymphatic disorders

Ian C.Chetter and Daniel Carradice

Part 11: Abdominal

63.History and examination of the abdomen

Dhananjaya Sharma

64.The abdominal wall, hernia and umbilicus

Bruce R.Tulloh and Barbora East

65.The peritoneum, mesentery, greater omentum, and retroperitoneal space

J. Calvin Coffey

66.The oesophagus

Simon Y.K Law and Ian Y.H.Wong

67.The stomach and duodenum

Timothy J Underwood, John N. Primrose

68. Bariatric and metabolic surgery　

Richard Welbourn and Dimitri J. Pournaras

69. The liver

Ashley R. Dennison & Guy J. Maddern

70. The spleen

Pawanindra Lal

71. The gall bladder and bile ducts

Avinash N.Supe and Ramkrishna Y.Prabhu

72. The pancreas

Satyajit Bhattacharya

73. Functional disorders of the intestine

Charles H. Knowles

74. The small intestines

Gordon L. Carlson and Jonathan C. Epstein

75. Inflammatory bowel disease

P. Ronan O'Connell and Nicola S. Fearnhead

76.The vermiform appendix

Jurgen Mulsow

77. The large intestines

Stephen Brown and Cat Boereboom

78. Intestinal obstruction

James Hill

79. The rectum

David G. Jayne and Aaron J.Quyn

80. The anus and anal canal

Malcolm A. West and Karen P. Nugent

Part 12: Genitourinary

81. Urinary symptoms and investigations

Rajeev Kumar and John K. Mellon

82. The kidney and ureters

Nitin Kekre

83. The urinary bladder

Sachin Malde

84.The prostate and seminal vesicles

Anant Kumar and Oussama Elhage

85.Urethra and penis

Sanjay B.Kulkarni

86. Testis and scrotum

Tet L.Yap

87.Gynaecology

Monica Mittal, Prasanna Raj Supramaniam,and Christian M. Becker

Part 13: Transplantation

88.Kidney transplantation and the principles of transplantation

Michael L. Nicholson

89.Liver transplantation

Mohamed Rela & Abdul Rahman Hakeem

90. Pancreas transplantation

James P. Hunter and Peter J.Friend

91. Intestinal and multivisceral transplantation

Neil Russell & Andrew Butler

92. Heart and Lung Transplantation

Stephen C. Clark

This ninth edition of the Textbook of Family Medicine, edited by Drs. Robert E. Rakel and David P. Rakel, remains your #1 choice for complete guidance on the principles of family medicine, primary care in the community, and all aspects of clinical practice. Ideal for both residents and practicing physicians, this medical reference book includes evidence-based, practical information to optimize patient care and prepare you for the ABFM exam. A clean, quick-reference layout makes it easy for you to put information to work immediately in your practice. Gain a new understanding of the patient-centered medical home and how to achieve this status in outpatient clinics. Make the most effective care decisions with help from "Evidence vs. Harm" icons that guide you through key treatments of common medical conditions. Take advantage of today's most useful online resources with a convenient list of outstanding clinical websites. Quickly spot "Best Evidence Recommendations" with special boxes located throughout the text, and glean helpful tips on diagnosis and therapy from "Key Points" boxes found on every page. Quickly access content with an efficient new layout that includes more than 1,000 tables and full-color illustrations; treatment boxes for a concise overview of how to treat various conditions; Grade A SORT recommendations; and key points highlighting the major takeaways of each chapter. Take advantage of an enhanced focus on team-based care as the role of primary care providers evolves, and stay up to date on the most current practice guidelines with evidence-based information throughout. View 30 immersive procedural videos online from Procedures Consult, including chest tube placement, knee injection, vasectomy, vaginal tear repair, skin biopsy, colposcopy, IUD insertion, and more. Remain at the forefront of the field with coverage on self-care, the emergence of tobacco alternatives such as e-cigarettes, and the changing picture of cancer in America. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices. The Textbook of Family Medicine continues to provide the latest, most comprehensive coverage of family medicine practice.

For more than 65 years, this best-selling text by Drs. Barbara J. Bain, Imelda Bates, and Mike A. Laffan has been the worldwide standard in laboratory haematology. The 12th Edition of Dacie and Lewis Practical Haematology continues the tradition of excellence with thorough coverage of all of the techniques used in the investigation of patients with blood disorders, including the latest technologies as well as traditional manual methods of measurement. You'll find expert discussions of the principles of each test, possible causes of error, and the interpretation and clinical significance of the findings. A unique section on haematology in under-resourced laboratories. Ideal as a laboratory reference or as a comprehensive exam study tool. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. diagnosis, molecular testing, blood transfusion- and much more. Complete coverage of the latest advances in the field. An expanded section on coagulation now covers testing for new anticoagulants and includes clinical applications of the tests.

Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology.

Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation.

Key features:

Fully integrated approach to the molecular aspects of human genetics, genomics, and cell biology

Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms

Summary boxes at the end of each chapter provide clear learning points

Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study

Reorganized into five sections for improved access to related topics

Also new to this edition – brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics

A proven and popular textbook for upper-level undergraduates and graduate students, the new edition of Human Molecular Genetics remains the ‘go-to’ book for those studying human molecular genetics or genomics courses around the world.

Table of Contents

Part 1: Basics of DNA, Chromosomes, Cells, Development, and Inheritance

1. Basic Principles of Nucleic Acid Structure and Gene Expression.

2. Fundamentals of Cells and Chromosomes.

3. Fundamentals of Cell-Cell Interactions and Immune System Biology.

4. Aspects of Early Mammalian Development, Cell Differentiation, and Stem Cells.

5. Patterns of Inheritance.

Part 2: Understanding Genomes

6. Core DNA Technologies: Amplifying DNA, Nucleic Acid Hybirdization, and DNA Sequencing.

7. Analyzing the Structure and Expression of Genes and Genomes.

8. Principles of Genetic Manipulation of Mammalian Cells.

9. Uncovering the Architecture and Workings of the Human Genome.

10. Gene Regulation and the Epigenome.

Part 3: Genetic Variation Between Individuals and Species

11. An Overview of Human Genetic Variation.

12. Human Population Genetics.

13. Comparative Genomics and Genome Evolution.

14. Human Evolution.

Part 4: Human Genetic Disease

15. Chromosomal Abnormalities and Structural Variants.

16. Molecular Pathology: Connecting Phenotypes to Genotypes.

17. Mapping and Identifying Genes for Monogenic Disorders.

18. Complex Disease: Identifying Susceptibility Factors and Understanding Pathogenesis.

19. Cancer Genetics and Genomics.

Part 5: Applied Human Molecular Genetics

20. Genetic Testing in Healthcare and the Law.

21. Model Organisms and Modeling Disease.

22. Genetic Approaches to Treating Disease.

This regional textbook of anatomy is aimed at trainee surgeons and medical students. Throughout it is rich in applied clinical content, knowledge of which is essential for both clinical examination and surgical procedures. Although regional in approach each chapter is structured to clearly explain the structure and function of the component systems. The author brings his continuing experience of teaching anatomy to trainee surgeons to ensure the contents reflects the changing emphasis of anatomical knowledge now required. Contents continues to evolve to reflect need of trainee surgeons preparing for the MRCS and similar examinations Continued increase in clinical application and selectivity in anatomical detail Further refinement of anatomical drawings Contents continues to evolve to reflect need of trainee surgeons preparing for the MRCS and similar examinations. Continued increase in clinical application and selectivity in anatomical detail. Further refinement of anatomical drawings.

Genetics today is inexorably focused on DNA. The theme of Introduction to Genetics: A Molecular Approach is therefore the progression from molecules (DNA and genes) to processes (gene expression and DNA replication) to systems (cells, organisms and populations). This progression reflects both the basic logic of life and the way in which modern biological research is structured. The molecular approach is particularly suitable for the large number of students for whom genetics is a part of a broader program in biology, biochemistry, the biomedical sciences, and biotechnology.

Introduction to Genetics presents the basic facts and concepts with enough depth of knowledge to stimulate students to move on to more advanced aspects of the subject. The book is divided into three parts. Part 1 examines the function of the gene as a unit of biological information. Part 2 studies the role of the gene as a unit of inheritance. And Part 3 explores some of the areas of research that are responsible for the high profile that genetics has in our modern world, from agriculture and industry to medicine and forensics, and the ethical challenges that genetic knowledge imparts.

Introduction to Genetics is available for purchase as an e-book in its entirety or as individual chapters, and as a 1-year or 6-month rental.