This volume presents the proceedings of the International Conference on Biomedical and Health Informatics (ICBHI). The conference was a new special topic conference and a common initiative by the International Federation of Medical and Biological Engineering (IFMBE) and IEEE Engineering in Medicine and Biology Society (IEEE- EMBS). BHI2015 was held in Haikou, China, 8-10 October 2015. The main theme of the BHI2015 is "The Convergence: Integrating Information and Communication Technologies with Biomedicine for Global Health". The ICBHI2015 proceedings examine enabling technologies of sensors, devices and systems that optimize the acquisition, transmission, processing, storage, retrieval, use of biomedical and health information as well as to report novel clinical applications of health information systems and the deployment of m-Health, e-Health, u-Health, p-Health and Telemedicine.

Accelerated Path to Cures provides a transformative perspective on the power of combining advanced computational technologies, modeling, bioinformatics and machine learning approaches with nonclinical and clinical experimentation to accelerate drug development. This book discusses the application of advanced modeling technologies, from target identification and validation to nonclinical studies in animals to Phase 1-3 human clinical trials and post-approval monitoring, as alternative models of drug development. As a case of successful integration of computational modeling and drug development, we discuss the development of oral small molecule therapeutics for inflammatory bowel disease, from the application of docking studies to screening new chemical entities to the development of next-generation in silico human clinical trials from large-scale clinical data. Additionally, this book illustrates how modeling techniques, machine learning, and informatics can be utilized effectively at each stage of drug development to advance the progress towards predictive, preventive, personalized, precision medicine, and thus provide a successful framework for Path to Cures.

This book describes breath signal processing technologies and their applications in medical sample classification and diagnosis. First, it provides a comprehensive introduction to breath signal acquisition methods, based on different kinds of chemical sensors, together with the optimized selection and fusion acquisition scheme. It then presents preprocessing techniques, such as drift removing and feature extraction methods, and uses case studies to explore the classification methods. Lastly it discusses promising research directions and potential medical applications of computerized breath diagnosis. It is a valuable interdisciplinary resource for researchers, professionals and postgraduate students working in various fields, including breath diagnosis, signal processing, pattern recognition, and biometrics.

Healthcare has become an extremely important and relevant topic in day to day discussions ever since the COVID-19 pandemic has been encountered by the global population. This has led to a renewed focus and attention that researchers from every discipline have put in to realize better strategies for healthcare management in general. This book is an attempt to put to use recent advancements in the field of the Internet of Medical Things often called IoMT, which is an extension of IoT for real-time, data analytics-driven prompt and quality healthcare to global citizens. Security has been always a challenge with pervasive technologies like IoMT and IoT, and thus usage of disruptive technology like blockchain to offset the security concerns that surround the data and network management. Therefore, this book is an honest attempt to provide directions to applied areas of research in IoMT for healthcare with the aid and help of Blockchain Technologies.

This book constitutes the thoroughly refereed post-workshop proceedings at PAKDD Workshops 2017, held in conjunction with PAKDD, the 21st Pacific-Asia Conference on Knowledge Discovery and Data Mining in May 2017 in Jeju, South Korea. The 17 revised papers presented were carefully reviewed and selected from 38 submissions. The workshops affiliated with PAKDD 2017 include: Workshop on Machine Learning for Sensory Data Analysis (MLSDA), Workshop on Biologically Inspired Data Mining Techniques (BDM), Pacific Asia Workshop on Intelligence and Security Informatics (PAISI), and Workshop on Data Mining in Business Process Management (DM-BPM).

This book constitutes the refereed joint proceedings of the International Workshop on Bio-Imaging and Visualization for Patient-Customized Simulations, BIVPCS 2017, and the International Workshop on Point-of-Care Ultrasound, POCUS 2017, held in conjunction with the 20th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2017, in Quebec City, QC, Canada, in September 2017. The 12 full papers presented at BIVPCS 2017 and the 7 full papers presented at POCUS 2017 were carefully reviewed and selected. The papers feature research from complementary fields such as signal and image processing, mechanics, computational vision, mathematics, physics, informatics, computer graphics, bio-medical-practice, psychology and industry as well as ultrasound image systems applications.

This book constitutes the thoroughly refereed post-workshop proceedings of the International Workshop on Medical Computer Vision, MCV 2016, and of the International Workshop on Bayesian and grAphical Models for Biomedical Imaging, BAMBI 2016, held in Athens, Greece, in October 2016, held in conjunction with the 19th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2016. The 13 papers presented in MCV workshop and the 6 papers presented in BAMBI workshop were carefully reviewed and selected from numerous submissions. The goal of the MCV workshop is to explore the use of "big data" algorithms for harvesting, organizing and learning from large-scale medical imaging data sets and for general-purpose automatic understanding of medical images. The BAMBI workshop aims to highlight the potential of using Bayesian or random field graphical models for advancing research in biomedical image analysis.

The two-volume set LNCS 10286 + 10287 constitutes the refereed proceedings of the 8th International Conference on Digital Human Modeling and Applications in Health, Safety, Ergonomics, and Risk Management, DHM 2017, held as part of HCI International 2017 in Vancouver, BC, Canada. HCII 2017 received a total of 4340 submissions, of which 1228 papers were accepted for publication after a careful reviewing process. The 75 papers presented in these volumes were organized in topical sections as follows: Part I: anthropometry, ergonomics, design and comfort; human body and motion modelling; smart human-centered service system design; and human-robot interaction. Part II: clinical and health information systems; health and aging; health data analytics and visualization; and design for safety.

Daryoush Daniel Vaziri illustrates that the use of mixed methods designs may support the induction of more subtle and complete theories about older adults' use of technologies for the support of active and healthy aging. The results show that older adults' social contexts and environments considerably affect their perspectives, practices and attitudes with respect to health, quality of life, well-being and technology use for active and healthy aging support. Results were collected with older adults aged 60+ as well as relevant secondary stakeholders like caregivers, policy makers or health insurance companies.

This book constitutes the thoroughly refereed post-conference proceedings of the Second International Workshop on Data Management and Analytics for Medicine and Healthcare, DMAH 2016, in New Delhi, India, in September 2016, held in conjunction with the 42nd International Conference on Very Large Data Bases, VLDB 2016. The 7 revised full papers presented together with 2 invited papers and 3 keynote abstracts were carefully reviewed and selected from 11 initial submissions. The papers are organized in topical sections on knowledge discovery of biomedical data; managing, querying and processing of medical image data; information extraction and data integration for biomedical data; and health information systems.

This two volume set LNBI 10208 and LNBI 10209 constitutes the proceedings of the 5th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2017, held in Granada, Spain, in April 2017. The 122 papers presented were carefully reviewed and selected from 309 submissions. The scope of the conference spans the following areas: advances in computational intelligence for critical care; bioinformatics for healthcare and diseases; biomedical engineering; biomedical image analysis; biomedical signal analysis; biomedicine; challenges representing large-scale biological data; computational genomics; computational proteomics; computational systems for modeling biological processes; data driven biology - new tools, techniques and resources; eHealth; high-throughput bioinformatic tools for genomics; oncological big data and new mathematical tools; smart sensor and sensor-network architectures; time lapse experiments and multivariate biostatistics.

This two volume set LNBI 10208 and LNBI 10209 constitutes the proceedings of the 5th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2017, held in Granada, Spain, in April 2017. The 122 papers presented were carefully reviewed and selected from 309 submissions. The scope of the conference spans the following areas: advances in computational intelligence for critical care; bioinformatics for healthcare and diseases; biomedical engineering; biomedical image analysis; biomedical signal analysis; biomedicine; challenges representing large-scale biological data; computational genomics; computational proteomics; computational systems for modeling biological processes; data driven biology - new tools, techniques and resources; eHealth; high-throughput bioinformatic tools for genomics; oncological big data and new mathematical tools; smart sensor and sensor-network architectures; time lapse experiments and multivariate biostatistics.

This book introduces zero-effort technologies (ZETs), an emerging class of technologies that require little or no effort from the people who use them. ZETs use advanced computing techniques, such as computer vision, sensor fusion, decision-making and planning, machine learning, and the Internet of Things to autonomously perform the collection, analysis, and application of data about the user and/or his/her context. This book begins with an overview of ZETs, then presents concepts related to their development, including pervasive intelligent technologies and environments, design principles, and considerations regarding use. The book discusses select examples of the latest in ZET development before concluding with thoughts regarding future directions of the field.

This book constitutes the refereed joint proceedings of the Third International Workshop on Deep Learning in Medical Image Analysis, DLMIA 2017, and the 6th International Workshop on Multimodal Learning for Clinical Decision Support, ML-CDS 2017, held in conjunction with the 20th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2017, in Quebec City, QC, Canada, in September 2017. The 38 full papers presented at DLMIA 2017 and the 5 full papers presented at ML-CDS 2017 were carefully reviewed and selected. The DLMIA papers focus on the design and use of deep learning methods in medical imaging. The ML-CDS papers discuss new techniques of multimodal mining/retrieval and their use in clinical decision support.

This book constitutes the thoroughly refereed post-conference proceedings of the International Conference for Smart Health, ICSH 2017, held in Hong Kong, China,in June 2017.The 18 full papers and 13 short papers presented were carefully reviewed and selectedfrom 38 submissions. They focus on studies on the principles, approaches, models, frameworks, new applications, and effects of using novel information technology to address healthcare problems and improve social welfare.

This book constitutes the refereed proceedings of the 6th International Conference on Health Information Science, HIS 2017, held in Moscow, Russia, in October 2017. The 11 full papers and 7 short papers presented were carefully reviewed and selected from 44 submissions. The papers feature multidisciplinary research results in health information science and systems that support health information management and health service delivery. They relate to all aspects of the conference scope, such as medical/health/biomedicine information resources such as patient medical records, devices and equipments, software and tools to capture, store, retrieve, process, analyze, and optimize the use of information in the health domain; data management, data mining, and knowledge discovery, management of publichealth, examination of standards, privacy and security issues; computer visualization and artificial intelligence for computer aided diagnosis; development of new architectures and applications for health information systems.

This book discusses the latest advances in human factors and ergonomics, focusing on methods for improving quality, safety, efficiency, and effectiveness in patient care. By emphasizing the physical, cognitive and organizational aspects of human factors and ergonomics applications, it reports on various perspectives, including those of clinicians, patients, health organizations and insurance providers. The book describes cutting-edge applications, highlighting the best practices of staff interactions with patients, as well as interactions with computers and medical devices. It also presents new findings related to improved organizational outcomes in healthcare settings, and approaches to modeling and analysis specifically targeting those work aspects unique to healthcare. Based on the AHFE 2016 International Conference on Human Factors and Ergonomics in Healthcare, held on July 27-31, 2016, in Walt Disney World (R), Florida, USA, the book is intended as timely reference guide for both researchers involved in the design of healthcare systems and devices and healthcare professionals aiming at effective and safe health service delivery. Moreover, by providing a useful survey of cutting-edge methods for improving organizational outcomes in healthcare settings, the book also represents an inspiring reading for healthcare counselors and international health organizations.

This book constitutes the refereed joint proceedings of the 6th Joint International Workshop on Computing and Visualization for Intravascular Imaging and Computer Assisted Stenting, CVII-STENT 2017, and the Second International Workshop on Large-Scale Annotation of Biomedical Data and Expert Label Synthesis, LABELS 2017, held in conjunction with the 20th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2017, in Quebec City, QC, Canada, in September 2017. The 6 full papers presented at CVII-STENT 2017 and the 11 full papers presented at LABELS 2017 were carefully reviewed and selected. The CVII-STENT papers feature the state of the art in imaging, treatment, and computer-assisted intervention in the field of endovascular interventions. The LABELS papers present a variety of approaches for dealing with few labels, from transfer learning to crowdsourcing.

This book constitutes the revised selected papers from the 5th International Workshop on Clinical Image-Based Procedures, CLIP 2016, held in conjunction with MICCAI 2016 in Athens, Greece, in October 2016. The 10 papers presented in this volume were carefully reviewed and selected from 16 submissions. Specific topics include various image segmentation and registration techniques, applied to various parts of the body. They range from interventional planning to navigation of devices and navigation to the anatomy of interest. Clinical applications cover the skull, the cochlea, cranial nerves, the aortic valve, wrists, and the abdomen, among others.

This book constitutes the thoroughly refereed post-workshop proceedings of the International Workshop on Brain Lesion, as well as the challenges on Brain Tumor Segmentation (BRATS), Ischemic Stroke Lesion Image Segmentation (ISLES), and the Mild Traumatic Brain Injury Outcome Prediction (mTOP), held in Athens, October 17, 2016, in conjunction with the International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2016. The 26 papers presented in this volume were carefully reviewed. They present the latest advances in segmentation, disease prognosis and other applications to the clinical context.

This book constitutes the refereed proceedings of the 7th International Conference on Information Technology in Bio- and Medical Informatics, ITBAM 2016, held in Porto, Portugal, in September 2016, in conjunction with DEXA 2016. The 9 revised long papers presented together with 11 poster papers were carefully reviewed and selected from 26 submissions. The papers address the following topics: biomedical data analysis and warehousing; information technologies in brain science; and social networks and process analysis in biomedicine.

This book constitutes the thoroughly refereed post-conference proceedings of theInternational Conference for Smart Health, ICSH 2016, held in Haikou, Hainan, China, in December 2016. The 23 full papers presented were carefully reviewed and selected from 52 submissions.They are organized around the following topics: big data and smart health; health data analysis and management; healthcare intelligent systems and clinical practice; medical monitoring and information extraction; clinical and medical data mining.

This book constitutes the proceedings of the 25th International Conference on Information Processing in Medical Imaging, IPMI 2017, held at the Appalachian State University, Boon, NC, USA, in June 2017. The 53 full papers presented in this volume were carefully reviewed and selected from 147 submissions. They were organized in topical sections named: analysis on manifolds; shape analysis; disease diagnosis/progression; brain networks an connectivity; diffusion imaging; quantitative imaging; imaging genomics; image registration; segmentation; general image analysis.

Have you ever experienced the burden of an adverse event or a near-miss in healthcare and wished there was a way to mitigate it? This book walks you through a classic adverse event as a case study and shows you how. It is a practical guide to continuously improving your healthcare environment, processes, tools, and ultimate outcomes, through the discipline of human factors. Using this book, you as a healthcare professional can improve patient safety and quality of care. Adverse events are a major concern in healthcare today. As the complexity of healthcare increases-with technological advances and information overload-the field of human factors offers practical approaches to understand the situation, mitigate risk, and improve outcomes. The first part of this book presents a human factors conceptual framework, and the second part offers a systematic, pragmatic approach. Both the framework and the approach are employed to analyze and understand healthcare situations, both proactively-for constant improvement-and reactively-learning from adverse events. This book guides healthcare professionals through the process of mapping the environmental and human factors; assessing them in relation to the tasks each person performs; recognizing how gaps in the fit between human capabilities and the demands of the task in the environment have a ripple effect that increases risk; and drawing conclusions about what types of changes facilitate improvement and mitigate risk, thereby contributing to improved healthcare outcomes.

This book constitutes the refereed proceedings of the International Conference on Brain and Health Informatics, BHI 2016, held in Omaha, USA, in October 2016. The 37 revised full papers, including two workshop papers from BAI 2016, presented were carefully reviewed and selected for inclusion in the book. The papers are organized in topical sections on cognitive and computational foundations of brain science; investigations of human information processing systems; brain big data analytics, curation and management; new methodologies for brain and mental health; brain-inspired intelligence and computing; brain and artificial intelligence.