Male Reproductive Function gives an up-to-date review on the physiology and disease processes associated with the male reproductive system. The first few chapters describe the regulation of the functions of the testis and the integration of its components: germ cells, Sertoli cells and Leydig cells. This is followed by a description of puberty and aging, and the disorders or dysfunction that may be associated with these physiological processes. Discussions on the current methods for the diagnosis and treatment of male hypogonadism, male infertility and male sexual dysfunction follow, with detailed descriptions of types of androgen replacement and the benefits and risks of such treatment. The book concludes with the development of male contraception and the possible influence of the environment on the male reproductive system. Male Reproductive Function represents a conglomeration of the efforts of experts in andrology from all over the world, both in basic cellular/molecular biology as well as in clinical science and practice. This book is suitable for endocrinologists, urologists, general internists, gynecologists and other students in the field of male reproduction.

Volume Two advances the exploration of the fundamental principles of oxidative stress and toxicity on male (and female) reproduction. It includes the advances in research on male reproductive health, the impact of environmental factors, the protective measures using bioactive compounds and traditional medicines, and how to limit toxic exposure. It includes coverage of: Oxidative stress and male infertility Environmental stressors and sexual health Heavy metals, pesticides, fine particle toxicity and male reproduction Protective measures against oxidative stress in gametes/embryos by using bioactive compounds/phytomedicines in Assisted Reproductive Technology (ART) Role of reactive oxygen species on female reproduction Radiation and mutagenic factors affecting the male reproductive system Both volumes provide a comprehensive look at the most basic concepts and advanced research being conducted by world famous scientists and researchers in male infertility and reproduction.

Drawing on never before used archival materials, Replacing the Dead exposes the history of Soviet and Russian abortion policy. It is not unusual for nations recovering from wars to incentivize their populations to raise their birthrates. The post-World War II Soviet pronatalism campaign attempted this on an unprecedented scale, aiming to replace a lost population of 27 million. Why, then, did the USSR re-legalize abortion in 1955? Mie Nakachi uses previously hidden archival data to reveal that decisions made by Stalin and Khruschev under the rubric of 'family law' created a society of broken marriages, "fatherless" children, and abortions, each totaling in the tens of millions. The government reversed laws regarding paternal responsibility, thereby encouraging men to impregnate unmarried women and widows, and blocked available contraception, overriding the advice of the medical establishment. Some 8.7 million out-of-wedlock children were born between 1945 and 1955 alone. In the absence of serious commitment to supporting Soviet women who worked full-time, the policy did extensive damage to gender relations and the welfare of women and children. Women, famous cultural figures, and Soviet professionals initiated a movement to improve women's reproductive health and make all children equal. Because Soviet leaders did not allow any major reform, an abortion culture grew among Soviet women and spread throughout the Soviet sphere, including Eastern Europe and China. Based on groundbreaking research, Replacing the Dead traces how the idea of women's right to an abortion emerged from an authoritarian society decades before it did in the West and why it remains the dominant method of birth control in present-day Russia.

Why are boxers actually better than briefs? How can hamsters help determine what's wrong with my sperm? My wife's already moody enough - why am I injecting her with even more hormones? Do I have to fill the whole cup at the fertility clinic? If you're a man going through fertility treatments with your significant other, these might be just a few of the questions you've faced. And, much to your dismay, you've realised the answers are a lot harder to find than you'd like. Until now. "How to Make Love to a Plastic Cup" is the man's guide to anything and everything related to infertility. But it's not just the same old boring nuts and bolts (no pun intended). Author Greg Wolfe, who went through four cycles of IVF on his journey to fatherhood, lays it all out with side-splitting humor. From understanding a woman's cycle, to 'porn etiquette' at the clinic, to detailed instructions on administering hormone shots, this book has everything a man needs to know to get the job done. For those men tired of searching the bookshelves for a volume that speaks to their experiences in the wild world of infertility (and for those women whose men don't quite get it), there's no need to look further. "How to Make Love to a Plastic Cup" covers the whole gamut of information for couples dealing with infertility in a fresh, engaging way any man can appreciate.

These proceedings of the 2018 XIII International Symposium on Spermatology focus on comparative biology, and encourages discussion and the exchange of ideas. The aim of this Symposium was to provide a unique opportunity and bring together scientists from a wide spectrum of research fields - human, domestic animals and other mammals, vertebrates, insects, and plants. The underlying focus is on the function of the spermatozoon - a common feature for sexual reproduction, but extremely varied. By exploring the variability, a better understanding of male reproductive functions can develop. These proceedings address the mechanisms of physiology and pathophysiology, rather than diagnosis and treatment. The symposium featured keynote lectures by invited speakers, followed by presentations on specific aspects of the general topic of the session. Experimental studies are given priority over clinical studies of patient populations. The proceedings comprise both keynote speakers' texts and selected free communications. Posters were considered for publication in the proceedings, and the volume includes exhibited materials on the work of prominent spermatologists, highlighting their important past achievements in the field.

Gain a foundational understanding of how endocrine and metabolic physiology affects other body systems in health and disease, including the clinical dimensions of reproductive endocrinology. Endocrine and Reproductive Physiology, a volume in the Mosby Physiology Series, explains the fundamentals of this complex subject in a clear and concise manner, while helping you bridge the gap between normal function and disease with pathophysiology content throughout the book. Helps you easily master the material in a systems-based curriculum with learning objectives, Clinical Concept boxes, highlighted key words and concepts, chapter summaries, self-study questions, and a comprehensive exam. Includes nearly 200 clear, 2-color diagrams that simplify complex concepts. Features clinical commentaries that show you how to apply what you've learned to real-life clinical situations. Keeps you current with recent advances in endocrine physiology with expanded material on reproductive endocrinology and metabolism, and many updates at the molecular and cellular level. Covers the latest developments in fertilization, pregnancy, and lactation, as well as fetal development, puberty, and the decline of reproductive function with age. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. Complete the Mosby Physiology Series! Systems-based and portable, these titles are ideal for integrated programs. Blaustein, Kao, & Matteson: Cellular Physiology and Neurophysiology Johnson: Gastrointestinal Physiology Koeppen & Stanton: Renal Physiology Cloutier: Respiratory Physiology Pappano & Weir: Cardiovascular Physiology Hudnall: Hematology: A Pathophysiologic Approach

Among the vast literature on contemporary reproductive technologies, Prosthetic Bodies stands out in its effective combination of insights, methods, and theories from the history of medicine, constructivist science and technology studies, and feminist theory. The double focus on IVF and related techniques, and fetal treatment and surgery, enables the identification of debatable tendencies within today's reproductive medicine: the translation of ever more medical problems basically unrelated to women's own reproductive health - and, in the case of fetal diagnosis and treatment, sometimes formerly even unrelated to reproduction as such - into medical indications for invasive, often highly experimental interventions in women's bodies. The analyses show how, through the operations and workings of reproductive technologies themselves, as well as a variety of discursive mechanisms within scientific language, today's recasting of men's fertility problems and children's congenital anomalies as women's reproductive problems comes to appear inevitable. The book challenges the ability of traditional forms of medical ethics and law to adequately identify this incremental process. The careful analyses and arguments in Prosthetic Bodies will be relevant to students of science and technology, gender studies, philosophy, medical ethics, and law, and others interested in the cultural, ethical, and political ramifications of contemporary reproductive technologies.

This book discusses many aspects of fetuses and motherhood from fields as wide as sociology and medicine. It examines changing perceptions of the fetus over recent decades, comparing western ideas with those of non-western countries; examining maternal mental health during COVID-19 and charting the ascent of the 'fetus' to a cult phenomenon, which has currently reappeared in the courts. This work, given its multifaceted approach, will be of interest to a varied and wide range of people, from parents to doctors and nurses, to anthropologists and ethnologists, to scientists, to students of various disciplines, to psychologists and psychoanalysts, to lawyers dealing with the topic and to a general public simply interested in these fundamental themes.

This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.

Women most fully experience the consequences of human reproductive technologies. Men who convene to evaluate such technologies discuss "them": the women who must accept, avoid, or even resist these technologies; the women who consume technologies they did not devise; the women who are the objects of policies made by men. So often the input of women is neither sought nor listened to. The privileged insights and perspectives that women bring to the consideration of technologies in human reproduction are the subject of these volumes, which constitute the revised and edited record of a Workshop on "Ethical Issues in Human Reproduction Technology: Analysis by Women" (EIRTAW), held in June, 1979, at Hampshire College in Amherst, Massachusetts. Some 80 members of the workshop, 90 percent of them women (from 24 states), represented diverse occupations and personal histories, different races and classes, varied political commitments. They included doctors, nurses, and scientists, lay midwives, consumer advocates, historians, and sociologists, lawyers, policy analysts, and ethicists. Each session, however, made plain that ethics is an everyday concern for women in general, as well as an academic profession for some.

The conceptualization of dementia has changed dramatically in recent years with the claim that, through early detection and by controlling several risk factors, a prevention of dementia is possible. Although encouraging and providing hope against this feared condition, this claim is open to scrutiny. This volume looks at how this new conceptualization ignores many of the factors which influence a dementia sufferers’ prognosis, including their history with education, food and exercise as well as their living in different epistemic cultures. The central aim is to question the concept of prevention and analyze its impact on aging people and aging societies.

Does Aging Stop? reveals the most paradoxical finding of recent aging research: the cessation of demographic aging. The authors show that aging stops at the level of the individual organism, and explain why evolution allows this. The implications of this counter-intuitive conclusion are profound, and aging research now needs to accept three uncomfortable truths. First, aging is not a cumulative physiological process. Second, the fundamental theory that is required to explain, manipulate, and probe the phenomena of aging comes from evolutionary biology. Third, strong-inference experimental strategies for aging must be founded in evolutionary research, not cell or molecular biology.
The result of fifteen years of research bringing together new applications of evolutionary theory, new models for demography, and massive experimentation, Does Aging Stop? advances an entirely new foundation for the scientific study of aging.

At last, a comprehensive collection of essays that examines and advances ethical evaluations of the controversial and increasingly popular practice of embryo adoption. In the United States alone, 400,000 frozen embryos created for in vitro fertilization exist but are no longer desired for that purpose. What are we morally obliged or permitted to do about these a oesparea embryos? More of their genetic parents are considering donating these embryos to others to gestate and raise. This practice is politically volatile (figuring in debates about embryonic stem cells) and medically and morally complex. At the present time within the Roman Catholic Church there is no official teaching on embryo adoption. Catholic ethical analyses grapple with the way embryo adoption comports with respect for embryonic human life yet challenges Catholic moral critiques of assisted reproductive technologies.

This volume is the first to bring together leading philosophers and theologians to engage Catholic debates about embryo adoption in an interactive format. The editors, a philosopher bioethicist and a moral theologian, provide a helpful overview of the practice and the arguments surrounding embryo adoption. They engage neglected Catholic ethical resources and issues to advance the current debate and chart new directions in Catholic moral thinking about this intriguing practice. The volume also includes a description of embryo adoption from a physician practitioner along with reflections from a couple who successfully adopted an embryo.

This book offers a vision of politics that govern the womb; from antiquity ('be fertile and replenish the earth'), through the ages (hysterectomy, to extirpate women's 'hysteria'), up to the present time (abortion wars; assisted reproduction), and into the future (reprogenetics; the artificial womb). It explores how the womb has served humanity, either tacitly or explicitly, through the ages and examines how women have accepted and still perceive the rules created by men as natural - including the new anti-abortion laws in the USA - because 'that is the way things are.' The book also explores how the emerging of assisted reproduction technologies and novel genetic tools (reprogenetics) will pose additional challenges to womb bearers, as all women will be made to reproduce with IVF. What is more, the advent of the artificial womb is in sight; the gender and social implications of this development would be enormous. Certainly not just another organ, the womb has been and remains a powerful tool that cannot be left to the decisions of half of the population. This book engages a wide audience, including women and men, professionals and laypersons who are interested in gender, politics, legislation, women's health, and ethics.

The conceptualization of dementia has changed dramatically in recent years with the claim that, through early detection and by controlling several risk factors, a prevention of dementia is possible. Although encouraging and providing hope against this feared condition, this claim is open to scrutiny. This volume looks at how this new conceptualization ignores many of the factors which influence a dementia sufferers' prognosis, including their history with education, food and exercise as well as their living in different epistemic cultures. The central aim is to question the concept of prevention and analyze its impact on aging people and aging societies.

Women most fully experience the consequences of human reproductive technologies. Men who convene to evaluate such technologies discuss Itthem ": the women who must accept, avoid, or even resist these technologies; the women who consume technologies they did not devise; the women who are the objects of policies made by of women is neither sought nor listened to. The men. So often the input and perspectives that women bring to the privileged insights consideration of technologies in human reproduction are the subject of these volumes, which constitute the revised and edited record of a Workshop on "Ethical Issues in Human Reproduction Technology: Analysis by W omen" (EIR TAW), held in June, 1979, at Hampshire College in Amherst, Massachusetts. Some 80 members of the workshop, 90 percent of them women (from 24 states), represented diverse occupations and personal histories, different races and classes, varied political commitments. They included doctors, nurses, and scientists, lay midwives, consumer advocates, historians, and sociologists, lawyers, policy analysts, and ethicists. Each session, however, made plain that ethics is an everyday concern for women in general, as well as an academic profession for some.

Human beings have been producing more twins, triplets, and quadruplets than ever before, due to the expansion of medically assisted conception. This book analyzes the anticipatory regimes of making multiple babies. With archival documents, participant observation, in-depth interviews, and registry data, this book traces the global and local governance of the assisted reproductive technologies (ARTs) used to tackle multiple pregnancy since the 1970s, highlighting the early promotion of single embryo transfer in Belgium and Japan and the making of the world's most lenient guidelines in Taiwan.

This book provides concrete scientific basis that we can conceive the possibility of modifying or even completely canceling aging process, despite the fact that aging is commonly regarded as the result of the overall effects of many uncontrollable degenerative phenomena. The authors illustrate in detail the mechanisms by which cells and the whole organism age. Actions by which it is possible, or will be possible within a limited time, to operate for modifying aging are also debated. The discussion is conducted within the frame and the concepts of evolutionary medicine, which is also indispensable for distinguishing between the manifestations of aging and: (i) diseases that worsen with age, and (ii) acceleration of normal aging rates, caused by unhealthy lifestyle habits and other avoidable factors. The book also discusses the impact of aging on overall mortality and the strange situation that, according to official statistics, aging does not exist as cause of death. This book is a turning point between a gerontology and geriatrics conceived as the study and vain treatment of an incurable condition and one in which these disciplines examine the how and why of a physiological phenomenon that can be modified up to a possible total control. This means transforming the medical prevention and treatment of physiological aging from the greatest failure to the greatest success of medicine.

In this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine's 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help readers live younger, longer. For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease - it is inevitable. But what if everything you think you know about ageing is wrong? What if ageing is a disease? And that disease is curable. In LIFESPAN, Dr. David Sinclair, one of the world's foremost authorities on genetics and ageing, argues just that. He has dedicated his life's work to chasing more than a longer lifespan - he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick - a circuit designed to halt reproduction in order to repair damage to the genome -has enabled earth's early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death. But genes aren't our destiny; we have more control over them than we've been taught to believe. We can't change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr. Sinclair will provide a scientifically-proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger longer. Readers will discover how a few simple lifestyle changes - like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy - can activate our vitality genes. Dr. Sinclair ends the book with a look to the near future, exploring what the world might look like - and what will need to change - when we are all living well to 120 or more. Dr. Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. THE EVOLUTION OF AGEING is destined to be the biggest book on genes, biology, and longevity of this decade.

Obesity is a continuing issue around the world and in many contexts. The growing number of obese people is an increasing concern for those in the medical profession, and obesity can pose specific challenges in relation to fertility and pregnancy. Patients who are obese require specific considerations and knowledge. Bringing together experts from a variety of specialties to examine the issues and challenges of obesity, this book discusses how obesity affects fertility, reproduction, and pregnancy. Beginning with an exploration of the epidemiology of obesity, further chapters focus on specific issues related to obesity and both male and female reproduction, the complications of obesity during pregnancy and labour, and the long term effects of obesity. This is the most comprehensive resource to examine the topic of obesity and reproductive issues, making it invaluable for medical students, professionals, and researchers in public policy and medicine.
Comprehensive examination of fertility issues arising from male and female obesityClinical knowledge and expertise given to the subjectsIn-depth examination through 47 chapters of a growing, but often overlooked, issue in fertility and pregnancy