Today, we are exposed to an increasing number of chemicals in the environment and there is a growing awareness of the effects of these chemicals on the ovaries. Infertility resulting from environmental exposures may not be obvious until the reproductive life span is waning. As such, the potential for xenobiotic-induced infertility needs to be better understood. In recent years, research into chemicals that have the potential to cause early menopause by destroying pre-antral ovarian follicles is gaining greater appreciation. Ovarian Toxicology, Second Edition represents a compilation of chapters prepared by researchers who have substantially contributed to our understanding of the impact of xenobiotics and environmental factors on ovarian function. The second edition substantially updates newly investigated ovotoxicants as well as improved mechanistic insights that have emerged since the first edition. Topics include: Ovarian physiology and the metabolism of xenobiotics The effect of pesticides, heavy metals, phthalates, BPA, and cigarette smoking on the ovaries Ovarian cancer, including endocrine effects and new perspectives on chemoresistance Epidemiology and human health risk assessment for environmental chemicals and pharmaceuticals The first book to focus specifically on ovarian toxicology, this resource is ideal for scientists in academia, regulatory agencies, and industry who would benefit from a survey of the impact of xenobiotic chemicals on ovarian function.

This practical manual on sperm analysis presents the diagnostic and therapeutic procedures that are used in andrology laboratories to analyse and assess male infertility. Diagnostic areas include: semen analysis and the biochemical, immunological and microbiological examination of human semen and spermatozoa; computer-aided sperm motility analysis; sperm ultrastructure; and assessment of sperm transport through the female tract and sperm fertilizing ability. The clinical relevance of various diagnostic procedures is also discussed. Therapeutic topics include sperm washing techniques, semen cryopreservation, and insemination procedures. The volume also covers safety in the andrology laboratory, technician training, and quality control. The text is extensively illustrated and will be an invaluable resource to all scientists and technicians who diagnose male infertility. It will also be of interest to researchers working in human gamete biology and reproductive physiology. The detailed methods described in the book are relevant to all hospital, commercial, and university laboratories involved in infertility diagnosis and treatment.

This is a reference manual for daily use in the Reproductive Medicine or Andrology laboratory, which goes beyond the literature available in the scientific journals by compiling insights into a detailed and applied clinical approach. All established practitioners in Reproductive Medicine will find much of practical relevance about the latest insights into sperm selection and analysis.

The hands-on guide that addresses the common barriers to achieving pregnancy and offers tips to maximize your potential for fertility For millions of people, starting a family is a lifelong dream. However, many face challenges in welcoming children into the world. According to the Centers for Disease Control and Prevention (CDC), approximately 12% of women in the US from ages 15 to 44 have difficulty getting pregnant or staying pregnant. A variety of factors exist that can contribute to infertility, such as ovulation disorders, uterine abnormalities, congenital defects, and a host of environmental and lifestyle considerations. But infertility is not just a female problem. For approximately 35% of couples with infertility, a male factor is identified along with a female factor, while in 8% of couples, a male factor is the only identifiable cause. Fortunately, there are many treatment options that offer hope. Getting Pregnant For Dummies discusses the difficulties related to infertility and offers up-to-date advice on the current methods and treatments to assist in conception. This easy-to-read guide will help you understand why infertility occurs, its contributing risk factors, and the steps to take to increase the chances of giving birth. From in vitro fertilization (IVF) to third party reproduction (donor sperm or eggs and gestational surrogacy) to lifestyle changes to understanding genetic information to insurance, legal and medication considerations, this bookcovers all the information you need to navigate your way to the best possible results. Packed with the latest information and new developments in medical technology, this book: Helps readers find real-life solutions to getting pregnant Covers the latest information on treatments for infertility for both women and men Offers advice on choosing the option best suited for an individual's unique situation Explains the different types and possible causes of infertility issues Provides insight to genetic testing information Provides suggestions for lifestyle changes that help prepare for conception Getting Pregnant For Dummies is an indispensable guide for every woman trying to conceive and for men experiencing infertility issues.

Sleeping patterns change with age, whether we are growing up, or growing old. While most people are prepared for the rapidly altering sleep patterns of growing children, the evidence suggests that many are unprepared for additional sleep changes in later life, either in themselves or in others. In this book, originally published in 1987, two research disciplines - social gerontology and sleep research - are brought together with the aim of providing a straightforward account of how sleep is changed and disrupted by the biological and social impact of ageing. Attention then focuses on the personal and clinical response to these changes. The use of sleeping drugs among elderly people is critically examined, and effective alternatives, including self-help practices and psychological therapies, are described. The influence of ageing on the recall and content of dreams is also considered. In the final chapter, the author comments on current styles of responding to sleep problems in old age and discusses the need and the scope for change. This book deals with topics of universal interest and provides valuable information for those professionally as well as personally concerned with sleep quality in later life, including health professionals (nurses, doctors, psychologists etc.) working with elderly people, gerontologists, and sleep researchers.

This contributed volume gathers the latest knowledge in the field of stem cells in human reproductive organs, as well as animal models, and to consider the possibility of using this knowledge for clinical purposes. The scope of the book covers both clinical and basic knowledge of stem cells in both reproductive medicine (gynecology and obstetrics) and regenerative medicine as well as cellular and molecular medicine and reproductive biology. Chapters on basic stem cell knowledge in human reproductive tissues and organs or animal models are included, as well as clinical knowledge on their role in the manifestation of infertility and cancer and their clinical use.

While the practice of surrogacy has existed for millennia, new fertility technologies have allowed women to act as gestational surrogates, carrying children that are not genetically their own. While some women volunteer to act as gestational surrogates for friends or family members, others get paid for performing this service. The first ethnographic study of gestational surrogacy in the United States, Labor of Love examines the conflicted attitudes that emerge when the ostensibly priceless act of bringing a child into the world becomes a paid occupation. Heather Jacobson interviews not only surrogate mothers, but also their family members, the intended parents who employ surrogates, and the various professionals who work to facilitate the process. Seeking to understand how gestational surrogates perceive their vocation, she discovers that many regard surrogacy as a calling, but are reluctant to describe it as a job. In the process, Jacobson dissects the complex set of social attitudes underlying this resistance toward conceiving of pregnancy as a form of employment. Through her extensive field research, Jacobson gives readers a firsthand look at the many challenges faced by gestational surrogates, who deal with complicated medical procedures, delicate work-family balances, and tricky social dynamics. Yet Labor of Love also demonstrates the extent to which advances in reproductive technology are affecting all Americans, changing how we think about maternity, family, and the labor involved in giving birth.

Premature Ejaculation presents a unique and innovative therapeutic program for the successful treatment of premature ejaculation. This descriptive and well-structured program is fundamentally different from traditional sex therapy and contemporary sexual medicine. Centred on the management of sexual excitement, it enables couples to prolong the length of intercourse without having to interrupt their lovemaking or resort to medication. The program's sexological approach also empowers couples with the skills and knowledge to strengthen their sex life leading to a healthier and happier relationship. Combining theory and practical instruction, Francois de Carufel's book promotes a better understanding of premature ejaculation. It offers a new perspective on the causes of this dysfunction and provides practitioners and therapists with concrete ways to assist men and women in improving their sex life. Premature Ejaculation will be of interest and value to health professionals and graduate students in all fields dealing with sexual difficulties, including psychology, social work, medicine, physical therapy, nursing and counselling.

Premature Ejaculation presents a unique and innovative therapeutic program for the successful treatment of premature ejaculation. This descriptive and well-structured program is fundamentally different from traditional sex therapy and contemporary sexual medicine. Centred on the management of sexual excitement, it enables couples to prolong the length of intercourse without having to interrupt their lovemaking or resort to medication. The program's sexological approach also empowers couples with the skills and knowledge to strengthen their sex life leading to a healthier and happier relationship. Combining theory and practical instruction, Francois de Carufel's book promotes a better understanding of premature ejaculation. It offers a new perspective on the causes of this dysfunction and provides practitioners and therapists with concrete ways to assist men and women in improving their sex life. Premature Ejaculation will be of interest and value to health professionals and graduate students in all fields dealing with sexual difficulties, including psychology, social work, medicine, physical therapy, nursing and counselling.

This title includes a number of Open Access chapters. Sarcopenia-the loss of muscle mass and strength that occurs with advancing age-is a major health challenge, particularly in North America, Europe, and Japan, which have large aging populations. This compendium volume is a valuable addition to the existing literature, providing state-of-the-art information on the most effective prevention and treatment options. Included are research articles on nutrition management and the prevention of sarcopenia; protein therapy for sarcopenia; effect of exercise on sarcopenia; and other therapeutic strategies, including antioxidants and steroids.

Offering a well-organized, straightforward approach to a highly complex subject, Larsen's Human Embryology, 6th Edition, provides easy-to-read, comprehensive coverage of human embryonic development for today's students. It integrates anatomy and histology with cellular and molecular mechanisms, focusing on both normal development and congenital anomalies. Highly illustrated with superb drawings and photographs, it features a strong clinical focus based on the most up-to-date scientific discoveries and understanding.Contains new information on gene editing via CRISPr technology, organoids and the study of human disease, transcription factors and signaling pathways, and single cell sequencing. Includes clinical scenarios that describe prevention, diagnosis, and treatment of human birth defects and disease. Features a superior art program, online animations, and high-quality drawings and photographs throughout-ideal for today's visual learners. * Includes a strong clinical emphasis through the use of Clinical Tasters, Embryology in Practice, and In the Clinic sections. Provides additional information on mechanisms of development and research approaches and strategies to establish these mechanisms with In the Research Lab sections. Begins each chapter with an overview of main points as well as a graphical summary, with key terms listed in bold type. Covers the embryology information that today's medical students need to know for Board exams, clinics, and more, in a readable, straightforward manner. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access 50 narrated animations, multiple-choice questions, and all of the text, figures, and references from the book on a variety of devices.

To celebrate the Center for Perinatal Biology s 40th Anniversary, an illustrious group gathered at Loma Linda University in February 2013. That gathering of experts and this volume of the proceedings are a tribute to the founder of the Center, Lawrence D. Longo, M.D. These chapters present contributions from individuals who in some way or another were influenced by Dr. Longo. Covering a wide range of topics, and illustrating the diversity of thinking and scientific interests, these proceedings address basic science through to clinical problems in the developmental programming of health and disease. "

In their desperate quest for conception, thousands of infertile couples from around the world travel to the global in vitro fertilization (IVF) hub of Dubai. In Cosmopolitan Conceptions Marcia C. Inhorn highlights the stories of 220 "reprotravelers" from fifty countries who sought treatment at a "cosmopolitan" IVF clinic in Dubai. These couples cannot find safe, affordable, legal, and effective IVF services in their home countries, and their stories offer a window into the world of infertility-a world that is replete with pain, fear, danger, frustration, and financial burden. These hardships dispel any notion that traveling for IVF treatment is reproductive tourism. The magnitude of reprotravel to Dubai, Inhorn contends, reflects the failure of countries to meet their citizens' reproductive needs, which suggests the necessity of creating new forms of activism that advocate for developing alternate pathways to parenthood, reducing preventable forms of infertility, supporting the infertile, and making safe and low-cost IVF available worldwide.

Infertility Saved My Life: Healing PCOS From The Inside Out exposes the raw teaching moments of Sarah Willoughby's journey to self-love through Polycystic Ovary Syndrome and secondary infertility. Within Infertility Saved My Life, Sarah Willoughby addresses the challenges and heartbreak she experienced while becoming a mum to three amazing children. She writes about her multiple miscarriages, as well as the trauma she endured, so that anyone still on their journey to parenthood can feel less alone in their loss and grief. Sarah's story peaks in 2009, when she ended up in intensive care after a disastrous IVF cycle. Lying in her hospital bed, she promised herself that if she survived, she would embrace her fears and empower others to do the same. Seven months later, Sarah Willoughby left the corporate world, emigrated to Australia and fell pregnant naturally twice with her daughters. Infertility Saved My Life shares the wisdom and insight that enabled Sarah to complete her family and begin a heart-centered life and business. She includes practical exercises and tools to help balance the reader's mind, body and spirit and improve their chances of having a baby.

The first volume in this new series from The Center for the Study of Child and Adolescent Development at The Pennsylvania State University focuses on the relationship between the biological stress circuits and the behavioral concomitants to stress in animals and humans. The participants at this conference, a tribute to Dean Evan G. Pattishall, Jr., discuss the developmental implications of their work in relation to the periods of infancy, childhood, and adolescence. For professionals, clinicians, and researchers in clinical, developmental, experimental, and health psychology, behavioral medicine, psychiatry, psychotherapy, and the neurosciences.

The Business of Being Made is the first book to critically analyze assisted reproductive technologies (ARTs) from a transdisciplinary perspective integrating psychoanalytic and cultural theories. It is a ground-breaking collection exploring ARTs through diverse methods including interview research, clinical case studies, psychoanalytic based ethnography, and memoir. Gathering clinicians and researchers who specialize in this area, this book engages current research in psychoanalysis, sociology, anthropology, philosophy and debates in feminist, queer and cultural theory about affect, temporality, and bodies. With psychoanalysis as its fulcrum, The Business of Being Made explores the social constructions and personal experiences of ARTs. Katie Gentile frames the cultural context, exploring the ways ARTs have become a complex form of playing with time, attempting to manufacture a hopeful future in the midst of growing global uncertainty. The contributors then present a range of varied experiences related to ARTs, including: Interviews with women and men undergoing ARTs; A psychoanalytic memoir of male infertility; Clinical research and work with transgender, gay and lesbian patients creating new Oedipal constellations, the experiences of LBGTQ people within the medical system and the variety of families that emerge; Research on the experiences of egg donors (now central to the business of ARTs) and a corresponding clinical case study of successful egg donation; The experiences of ongoing failure which is the often unacknowledged for ART procedures; How and when people choose to stop using ARTs; A psychoanalytic ethnography of a neonatal intensive care unit populated in part with the babies created through these technologies and their parents, haggard and in shock after years of failed attempts. Full of original material, The Business of Being Made conveys the ambivalence of these technologies without simplifying their complicated consequences for the bodies of individuals, the family, cultures, and our planet. This book will be relevant to clinicians, medical and psychological personnel working in assisted reproductive technologies and infertility, as well as academics working in the fields of sociology, literature, queer and feminist theories and at the intersections of cultural, critical and psychoanalytic theories.

The Business of Being Made is the first book to critically analyze assisted reproductive technologies (ARTs) from a transdisciplinary perspective integrating psychoanalytic and cultural theories. It is a ground-breaking collection exploring ARTs through diverse methods including interview research, clinical case studies, psychoanalytic based ethnography, and memoir. Gathering clinicians and researchers who specialize in this area, this book engages current research in psychoanalysis, sociology, anthropology, philosophy and debates in feminist, queer and cultural theory about affect, temporality, and bodies. With psychoanalysis as its fulcrum, The Business of Being Made explores the social constructions and personal experiences of ARTs. Katie Gentile frames the cultural context, exploring the ways ARTs have become a complex form of playing with time, attempting to manufacture a hopeful future in the midst of growing global uncertainty. The contributors then present a range of varied experiences related to ARTs, including: Interviews with women and men undergoing ARTs; A psychoanalytic memoir of male infertility; Clinical research and work with transgender, gay and lesbian patients creating new Oedipal constellations, the experiences of LBGTQ people within the medical system and the variety of families that emerge; Research on the experiences of egg donors (now central to the business of ARTs) and a corresponding clinical case study of successful egg donation; The experiences of ongoing failure which is the often unacknowledged for ART procedures; How and when people choose to stop using ARTs; A psychoanalytic ethnography of a neonatal intensive care unit populated in part with the babies created through these technologies and their parents, haggard and in shock after years of failed attempts. Full of original material, The Business of Being Made conveys the ambivalence of these technologies without simplifying their complicated consequences for the bodies of individuals, the family, cultures, and our planet. This book will be relevant to clinicians, medical and psychological personnel working in assisted reproductive technologies and infertility, as well as academics working in the fields of sociology, literature, queer and feminist theories and at the intersections of cultural, critical and psychoanalytic theories.

This book presents an ethnographic study on gestational surrogacy in India. It frames the ethnography of the surrogacy clinic in conversation with concerns raised in the arenas of law, policy, medical ethics, and global structural inequality about the ethics of transnational assisted reproductive technology (ART) practices. Engaging ethical discourses that both advocate for and trouble the subject of reproductive rights that remains of interest in feminist studies, the volume takes up the work of critical feminist, anthropological and science studies scholarship in India, the United States, and Europe concerned with reproductive technologies. Based on fieldwork and archival sources, the volume will be of great interest to scholars and researchers of ethnography, gender, social and public policy, South Asian studies, and global public health, especially reproductive health.

Based on the author's fieldwork at assisted conception clinics in England in the mid-1990s, this is the first ethnographic study of the new procreative practices of anonymous ova and embryo donation. Giving voice to both groups of women participating in the demanding donation experience - the donors on the one side and the ever-hopeful IVF recipients on the other - Konrad shows how one dimension of the new reproductive technologies involves an unfamiliar relatedness between nameless and untraceable procreative strangers. Offsetting informants' local narratives against traditional Western folk models of the 'sexed' reproductive body, the book challenges some of the basic assumptions underlying conventional biomedical discourse of altruistic donation that clinicians and others promote as "gifts of life." It brings together a wide variety of literatures from social anthropology, social theory, cultural studies of science and technology, and feminist bioethics to discuss the relationship between recent developments in biotechnology and changing conceptions of personal origins, genealogy, kinship, biological ownership and notions of bodily integrity.

Putting the ethical tools of philosophy to work, Ellen K. Feder seeks to clarify how we should understand "the problem" of intersex. Adults often report that medical interventions they underwent as children to "correct" atypical sex anatomies caused them physical and psychological harm. Proposing a philosophical framework for the treatment of children with intersex conditions one that acknowledges the intertwined identities of parents, children, and their doctors Feder presents a persuasive moral argument for collective responsibility to these children and their families."

One in six couples around the world experience infertility. Before undertaking expensive and intrusive assisted reproductive treatment such as in vitro fertilization, many seek advice from their physicians or dietitians on what foods and supplements might enhance their fertility. But health practitioners are often ill equipped to provide dietary recommendations in a scientifically based manner. Nutrition, Fertility, and Human Reproductive Function provides a comprehensive guide to clinicians on how they can best advise their patients to optimise fertility and reproductive function through optimal nutrition. Taking a holistic or "whole-of-life" approach, the book reviews the role of nutrition in human fertility and explores its effect on male and female reproductive physiology. Problem-orientated topics are arranged in chapters that each cover a specific clinical topic of interest, allowing easy reference by the practicing clinician. From the female perspective, the book covers the role of nutrition on essential reproductive processes such as ovulation, early embryo development, implantation, and sexual function, together with nutrition's influence on the duration of the reproductive life span. In the male context, it examines the effect of nutrition on hormone and sperm production as well as sexual function. The book also includes information on evidence-based complementary health approaches such as Traditional Chinese Medicine (TCM) and naturopathy. This book draws on the wide experience of several respected leaders in clinical nutrition who combine research expertise with clinical insight. The information contained herein will enable clinicians to make the best recommendations for their patients for optimising fertility.

Contains basic and up-to-date information on an emerging fish model Allows non-specialist readers to grasp the relevance of a wide research area Provides accurate and easy to access information on each of the 30 species Includes guidance for establishing a breeding colony Documents that Anemonefishes are useful model organisms for ecological, developmental and climate research

For centuries people have been puzzled by the inevitability of human aging. For most of the second half of the twentieth century aging remained a mystery, or an unsolved biological problem. At the end of the 20th century a remarkable scientific discovery emerged. It was not a single discovery in the usual sense, because it was based on a series of important interconnected insights over quite a long period of time. These insights made it possible for the very first time to understand the biological reasons for aging in animals and man. It can already be said, however, that the many observations and insights that explain aging will not be accepted as established knowledge for a long time. The field is still full of scientists, and non-scientists, who are just happy to go on speculating about the mystery of aging.