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Books > Medicine > Pre-clinical medicine: basic sciences > Human reproduction, growth & development

Coping With Uncertainty - Behavioral and Developmental Perspectives (Paperback): Davis S. Palermo Coping With Uncertainty - Behavioral and Developmental Perspectives (Paperback)
Davis S. Palermo
R1,474 Discovery Miles 14 740 Ships in 12 - 17 working days

The first volume in this new series from The Center for the Study of Child and Adolescent Development at The Pennsylvania State University focuses on the relationship between the biological stress circuits and the behavioral concomitants to stress in animals and humans. The participants at this conference, a tribute to Dean Evan G. Pattishall, Jr., discuss the developmental implications of their work in relation to the periods of infancy, childhood, and adolescence. For professionals, clinicians, and researchers in clinical, developmental, experimental, and health psychology, behavioral medicine, psychiatry, psychotherapy, and the neurosciences.

Clinical Nutrition and Aging - Sarcopenia and Muscle Metabolism (Hardcover): Chad Cox Clinical Nutrition and Aging - Sarcopenia and Muscle Metabolism (Hardcover)
Chad Cox
R3,554 Discovery Miles 35 540 Ships in 12 - 17 working days

This title includes a number of Open Access chapters. Sarcopenia-the loss of muscle mass and strength that occurs with advancing age-is a major health challenge, particularly in North America, Europe, and Japan, which have large aging populations. This compendium volume is a valuable addition to the existing literature, providing state-of-the-art information on the most effective prevention and treatment options. Included are research articles on nutrition management and the prevention of sarcopenia; protein therapy for sarcopenia; effect of exercise on sarcopenia; and other therapeutic strategies, including antioxidants and steroids.

Understanding Fertility (Hardcover): Gab Kovacs Understanding Fertility (Hardcover)
Gab Kovacs
R1,220 Discovery Miles 12 200 Ships in 12 - 17 working days

Infertility can have devastating physical, emotional and financial effects on people affected. It is a common problem, but can be hard to talk about, and hard to understand. In this concise book, Dr Kovacs, a reproductive gynaecologist who has spent the past 40 years working with patients facing fertility problems, focuses on and unpicks key misconceptions. In his clear explanations, he covers the basic physiology of conceiving, and describes the areas that have to be explored for those who have not yet been able to conceive. Specific chapters cover the three major problem areas: lack of releasing eggs, sperm problems, and abnormalities of the female passages. Treatment options are discussed for each of these areas, including technical details and a brief readable overview of their history. The many ways of parenting which are now available are also detailed. This is a recommended read for couples wanting to conceive, their friends and families, and anyone who wants to understand fertility.

The Business of Being Made - The temporalities of reproductive technologies, in psychoanalysis and culture (Paperback): Katie... The Business of Being Made - The temporalities of reproductive technologies, in psychoanalysis and culture (Paperback)
Katie Gentile
R1,469 Discovery Miles 14 690 Ships in 12 - 17 working days

The Business of Being Made is the first book to critically analyze assisted reproductive technologies (ARTs) from a transdisciplinary perspective integrating psychoanalytic and cultural theories. It is a ground-breaking collection exploring ARTs through diverse methods including interview research, clinical case studies, psychoanalytic based ethnography, and memoir. Gathering clinicians and researchers who specialize in this area, this book engages current research in psychoanalysis, sociology, anthropology, philosophy and debates in feminist, queer and cultural theory about affect, temporality, and bodies. With psychoanalysis as its fulcrum, The Business of Being Made explores the social constructions and personal experiences of ARTs. Katie Gentile frames the cultural context, exploring the ways ARTs have become a complex form of playing with time, attempting to manufacture a hopeful future in the midst of growing global uncertainty. The contributors then present a range of varied experiences related to ARTs, including: Interviews with women and men undergoing ARTs; A psychoanalytic memoir of male infertility; Clinical research and work with transgender, gay and lesbian patients creating new Oedipal constellations, the experiences of LBGTQ people within the medical system and the variety of families that emerge; Research on the experiences of egg donors (now central to the business of ARTs) and a corresponding clinical case study of successful egg donation; The experiences of ongoing failure which is the often unacknowledged for ART procedures; How and when people choose to stop using ARTs; A psychoanalytic ethnography of a neonatal intensive care unit populated in part with the babies created through these technologies and their parents, haggard and in shock after years of failed attempts. Full of original material, The Business of Being Made conveys the ambivalence of these technologies without simplifying their complicated consequences for the bodies of individuals, the family, cultures, and our planet. This book will be relevant to clinicians, medical and psychological personnel working in assisted reproductive technologies and infertility, as well as academics working in the fields of sociology, literature, queer and feminist theories and at the intersections of cultural, critical and psychoanalytic theories.

The Business of Being Made - The temporalities of reproductive technologies, in psychoanalysis and culture (Hardcover): Katie... The Business of Being Made - The temporalities of reproductive technologies, in psychoanalysis and culture (Hardcover)
Katie Gentile
R5,242 Discovery Miles 52 420 Ships in 12 - 17 working days

The Business of Being Made is the first book to critically analyze assisted reproductive technologies (ARTs) from a transdisciplinary perspective integrating psychoanalytic and cultural theories. It is a ground-breaking collection exploring ARTs through diverse methods including interview research, clinical case studies, psychoanalytic based ethnography, and memoir. Gathering clinicians and researchers who specialize in this area, this book engages current research in psychoanalysis, sociology, anthropology, philosophy and debates in feminist, queer and cultural theory about affect, temporality, and bodies. With psychoanalysis as its fulcrum, The Business of Being Made explores the social constructions and personal experiences of ARTs. Katie Gentile frames the cultural context, exploring the ways ARTs have become a complex form of playing with time, attempting to manufacture a hopeful future in the midst of growing global uncertainty. The contributors then present a range of varied experiences related to ARTs, including: Interviews with women and men undergoing ARTs; A psychoanalytic memoir of male infertility; Clinical research and work with transgender, gay and lesbian patients creating new Oedipal constellations, the experiences of LBGTQ people within the medical system and the variety of families that emerge; Research on the experiences of egg donors (now central to the business of ARTs) and a corresponding clinical case study of successful egg donation; The experiences of ongoing failure which is the often unacknowledged for ART procedures; How and when people choose to stop using ARTs; A psychoanalytic ethnography of a neonatal intensive care unit populated in part with the babies created through these technologies and their parents, haggard and in shock after years of failed attempts. Full of original material, The Business of Being Made conveys the ambivalence of these technologies without simplifying their complicated consequences for the bodies of individuals, the family, cultures, and our planet. This book will be relevant to clinicians, medical and psychological personnel working in assisted reproductive technologies and infertility, as well as academics working in the fields of sociology, literature, queer and feminist theories and at the intersections of cultural, critical and psychoanalytic theories.

The Reproductive Body at Work - The South African Bioeconomy of Egg Donation (Paperback): Verena Namberger The Reproductive Body at Work - The South African Bioeconomy of Egg Donation (Paperback)
Verena Namberger
R1,237 Discovery Miles 12 370 Ships in 12 - 17 working days

The transnational industry surrounding assisted reproductive technology and regenerative medicine is based on the unacknowledged labour of gamete providers, surrogates and research subjects, and benefits from low labour costs in 'enabling' sectors such as logistics and transport. This finding calls for a comprehensive analysis of how the contemporary intersection of neoliberal capitalism and the life sciences - in short, the bioeconomy - capitalises on the body and its (re)productive capacities. The Reproductive Body at Work uptakes this challenge as it explores the relations between value production, labour and the body in one particular realm of the global bioeconomy: the South African bioeconomy of 'egg donation'. It highlights different forms and dimensions of unacknowledged or precarious human labour that are constitutive for the procurement, brokering and circulation of oocytes as valuable resources. The analysis illustrates that the respective organisation of value and labour renegotiate what 'the' (re)productive body can do, which status and roles it is ascribed, which cultural and economic values it signifies and how it is experienced and enacted within a matrix of intersectional power relations. A theoretically profound contribution to the interdisciplinary debate on 'New materialism', The Reproductive Body at Work will appeal to students and researchers interested in fields such as gender studies, medical anthropology, cultural studies, sociology, political economy and science and technology studies.

Protein Metabolism and Homeostasis in Aging (Hardcover, 2010 ed.): Nektarios Tavernarakis Protein Metabolism and Homeostasis in Aging (Hardcover, 2010 ed.)
Nektarios Tavernarakis
R4,406 Discovery Miles 44 060 Ships in 10 - 15 working days

Aging is loosely defined as the accumulation of changes in an organism over time. At the cellular level such changes are distinct and multidimensional: DNA replication ceases, cells stop dividing, they become senescent and eventually die. DNA metabolism and chromosomal maintenance, together with protein metabolism are critical in the aging process. The focus of this book is on the role of protein metabolism and homeostasis in aging. An overview is provided of the current knowledge in the area, including protein synthesis, accuracy and repair, post-translational modifications, degradation and turnover, and how they define and influence aging. The chapters mainly focus on well-characterised factors and pathways, but new areas are also presented, where associations with aging are just being elucidated by current experimental data. Protein turnover, the balance between protein synthesis and protein degradation are carefully maintained in healthy cells. Chapters 1 and 2 illustrate that aging cells are characterised by alterations in the rate, level and accuracy of protein synthesis compared to young ones, and that mRNA translation, essential for cell growth and survival, is controlled at multiple levels. The theory that growth and somatic maintenance are believed to be antagonistic processes is described in Chapter 3: inhibition of protein synthesis results in decreased rates of growth and development, but also confers an extension of lifespan, as shown for example by the effects of dietary restriction in various models organisms.

Religion, Medicine and the Human Embryo in Tibet (Paperback): Frances Garrett Religion, Medicine and the Human Embryo in Tibet (Paperback)
Frances Garrett
R1,470 Discovery Miles 14 700 Ships in 12 - 17 working days

This book explores the cultural history of embryology in Tibet, in culture, religion, art and literature, and what this reveals about its medicine and religion. Filling a significant gap in the literature this is the first in-depth exploration of Tibetan medical history in the English language. It reveals the prevalence of descriptions of the development of the human body - from conception to birth - found in all forms of Tibetan religious literature, as well as in medical texts and in art. By analysing stories of embryology, Frances Garrett explores questions of cultural transmission and adaptation: How did Tibetan writers adapt ideas inherited from India and China for their own purposes? What original views did they develop on the body, on gender, on creation, and on life itself? The transformations of embryological narratives over several centuries illuminate key turning points in Tibetan medical history, and its relationship with religious doctrine and practice. Embryology was a site for both religious and medical theorists to contemplate profound questions of being and becoming, where topics such as pharmacology and nosology were left to shape secular medicine. The author argues that, in terms of religion, stories of human development comment on embodiment, gender, socio-political hierarchy, religious ontology, and spiritual progress. Through the lens of embryology, this book examines how these concerns shift as Tibetan history moves through the formative 'renaissance' period of the twelfth through to the seventeenth centuries.

Nutrition, Fertility, and Human Reproductive Function (Hardcover): Kelton  Tremellen, Karma Pearce Nutrition, Fertility, and Human Reproductive Function (Hardcover)
Kelton Tremellen, Karma Pearce
R5,117 Discovery Miles 51 170 Ships in 12 - 17 working days

One in six couples around the world experience infertility. Before undertaking expensive and intrusive assisted reproductive treatment such as in vitro fertilization, many seek advice from their physicians or dietitians on what foods and supplements might enhance their fertility. But health practitioners are often ill equipped to provide dietary recommendations in a scientifically based manner. Nutrition, Fertility, and Human Reproductive Function provides a comprehensive guide to clinicians on how they can best advise their patients to optimise fertility and reproductive function through optimal nutrition. Taking a holistic or "whole-of-life" approach, the book reviews the role of nutrition in human fertility and explores its effect on male and female reproductive physiology. Problem-orientated topics are arranged in chapters that each cover a specific clinical topic of interest, allowing easy reference by the practicing clinician. From the female perspective, the book covers the role of nutrition on essential reproductive processes such as ovulation, early embryo development, implantation, and sexual function, together with nutrition's influence on the duration of the reproductive life span. In the male context, it examines the effect of nutrition on hormone and sperm production as well as sexual function. The book also includes information on evidence-based complementary health approaches such as Traditional Chinese Medicine (TCM) and naturopathy. This book draws on the wide experience of several respected leaders in clinical nutrition who combine research expertise with clinical insight. The information contained herein will enable clinicians to make the best recommendations for their patients for optimising fertility.

Reproductive Tourism in the United States - Creating Family in the Mother Country (Hardcover): Lauren Jade Martin Reproductive Tourism in the United States - Creating Family in the Mother Country (Hardcover)
Lauren Jade Martin
R4,352 Discovery Miles 43 520 Ships in 12 - 17 working days

Lax federal oversight, high technology resources, privatized health care, a pluralist population, and a commitment to professional autonomy make the United States an ideal host for reproductive tourists. Those who are in possession of enough material resources and political savvy can subvert their countries' norms and laws regarding reproductive technologies, in effect becoming procreative outlaws. This book examines the United States as a destination for international consumers of assisted fertility services, including egg donation, surrogacy, and sex selection. It is based on interviews conducted with fertility industry insiders who market their services to an international clientele in three of the largest American hubs of the global fertility marketplace - New York City, Los Angeles, and San Francisco. By focusing on the providers rather than the consumers of assisted fertility services, the book shines a light on how professional ethics and norms, in addition to personal moralities, shape the practice of reproductive tourism.

Last Years of Long Lives - The Larvik Study (Paperback): Tor Inge Romoren Last Years of Long Lives - The Larvik Study (Paperback)
Tor Inge Romoren
R1,529 Discovery Miles 15 290 Ships in 12 - 17 working days

The Last Years of Long Lives is a unique account of that period of old age which precedes death. Based on 400 complete individual histories and covering a twenty-year period, it looks at the experiences of people over eighty years old in three important areas: disability, family life and health care. Using the life-course approach to research, it reveals rich data about the contributions of formal and informal care and how life expectancy and experiences of disability interact with experiences of care. The reader is invited to conceptualise these phenomena as processes in continuous time - processes that are sometimes long and complex, sometimes short and simple - and learns about the four types of disability career before death. At the same time, the author presents a three-stage model of informal care and examines the main patterns of formal service use. The Last Years of Long Lives presents a new way of looking at old age for students, researchers, practitioners and policy makers and gives a comprehensive picture of what has been called 'the fourth age'.

When the Bubble Bursts - Clinical Perspectives on Midlife Issues (Paperback): Eda Goldstein When the Bubble Bursts - Clinical Perspectives on Midlife Issues (Paperback)
Eda Goldstein
R1,614 Discovery Miles 16 140 Ships in 12 - 17 working days

There are common midlife events that account for the special narcissistic vulnerabilities of this period of life, and Eda Goldstein ably reviews these events and the theoretical perspectives commonly brought to bear on them. In When the Bubble Bursts, however, Goldstein's special concern is those individuals who come to midlife with heightened narcissistic vulnerabilities that make the navigation of this stage of life more difficult still. In understanding the latter such patients and devising a treatment approach appropriate to their "self" issues, Goldstein adopts a broadly self-psychological frame of reference. It is a matter, she finds again and again, of understanding how current stressors frustrate healthy self needs and trigger narcissistic vulnerabilities. Self-psychologically informed treatment, which, in Goldstein's pragmatic purview, embraces modalities that are, to varying degrees, supportive, psychodynamic, and psychoanalytic, reworks and strengthens self structures in helping patients find new ways of affirming their sense of self. Her substantive case studies, which accompany the reader through all the chapters in her study, draw on personal and supervisory experiences to illustrate crucial foci of the treatment process with a range of midlife patients in psychotherapy. Eda Goldstein presents a study that comprises an admirable blend of theoretical astuteness, clinical wisdom, and personal honesty. Her clinical study of midlife narcissistic pathology is bracketed by her balanced discussion of theoretical perspectives on adult development and her concluding consideration of the countertransference issues elicited by midlife patients in midlife therapists. When the Bubble Bursts is an edifying contribution to the literatures of psychodynamic psychotherapy, self psychology, and adult development.

Applications of Nonlinear Dynamics To Developmental Process Modeling (Paperback): Karl M. Newell, Peter C.M. Molenaar Applications of Nonlinear Dynamics To Developmental Process Modeling (Paperback)
Karl M. Newell, Peter C.M. Molenaar
R1,313 R1,164 Discovery Miles 11 640 Save R149 (11%) Ships in 12 - 17 working days

There has been an increasing interest in the application of dynamical systems to the study of development over the last decade. The explosion of the dynamical systems framework in the physical and biological sciences has opened the door to a new Zeitgeist for studying development. This appeal to dynamical systems by developmentalists is natural given the intuitive links between the established fundamental problems of development and the conceptual and operational scope of nonlinear dynamical systems. This promise of a new approach and framework within which to study development has led to some progress in recent years but also a growing appreciation of the difficulty of both fully examining the new metaphor and realizing its potential. Divided into 4 parts, this book is a result of a recent conference on dynamical systems and development held at Pennsylvania State University. The first 3 parts focus on the content domains of development that have given most theoretical and empirical attention to the potential applications of dynamical systems--physical growth and movement, cognition, and communication. These parts show that a range of nonlinear models have been applied to a host of developmental phenomena. Part 4 highlights two particular methodological issues that hold important implications for the modeling of developmental phenomena with dynamical systems techniques.

Biotechnologies Applied to Animal Reproduction - Current Trends and Practical Applications for Reproductive Management... Biotechnologies Applied to Animal Reproduction - Current Trends and Practical Applications for Reproductive Management (Hardcover)
Juan Carlos Gardon, Katy Satue
R3,954 Discovery Miles 39 540 Ships in 12 - 17 working days

This comprehensive volume focuses on recent trends and new technologies used in the management of reproduction in major farm animals, focusing on both males and females of bovine, equine, and porcine species. With chapters written by scientists who specialize in their respective topics, the volume presents a selection of different technologies that have been developed to assure reproductive success by improving reproductive efficiency, generating germplasm banks, and maintaining genetic diversity in cattle, horses, and pigs. In the last decade, reproductive technologies in veterinary medicine have progressed considerably, providing high profitability to livestock farms. This book provides basic and applied information on the most used reproductive technologies in bovine, equine, and porcine species for academics, scientists, and veterinarians. The volume discusses reproductive and postpartum management, reproductive ultrasound, sperm management, egg retrieval, artificial insemination, embryo transfer, nutrition, genetics, and certain clinical aspects, such as endocrinology and robustness of reproductive systems.

IVF in the Medically Complicated Patient - A Guide to Management (Paperback, 2nd edition): Nick Macklon IVF in the Medically Complicated Patient - A Guide to Management (Paperback, 2nd edition)
Nick Macklon
R2,147 Discovery Miles 21 470 Ships in 12 - 17 working days

Each patient seeking assisted reproduction has a unique set of circumstances that affects the outcome of treatment. Particularly challenging are those patients with pre-existing medical conditions or those receiving medical therapies that may impact the safety and success of their IVF treatments. Prior identification and preparation of the patient at increased risk of complications will enable the clinician to avoid problems in advance, anticipate the necessary management, and optimize outcomes. A new expanded edition of the prize-winning text IVF in the Medically Complicated Patient: A Guide to Management, Second Edition provides a readily accessible, authoritative, and didactic source of information to aid clinicians in this important field.

In Vitro Maturation of Human Oocytes (Paperback): Seang Lin Tan, Ri-Chen Chian, M. Buckett In Vitro Maturation of Human Oocytes (Paperback)
Seang Lin Tan, Ri-Chen Chian, M. Buckett
R1,790 Discovery Miles 17 900 Ships in 12 - 17 working days

The use of IVM in assisted reproductive technology continues to increase around the world. The major benefit of IVM is that significant numbers of oocytes can be collected from ovaries without recourse to ovarian stimulation. This reduces the costs, time, and risks associated with conventional IVF. Although initially limited to women with polycystic ovary syndrome who were at higher risk of problems following ovarian stimulation, IVM is increasingly used in women with normal ovulatory menstrual cycles. This authoritative text covers the current scientific knowledge of oocyte development and the understanding behind the techniques involved in the clinical application of IVM in assisted reproductive technologies. Short Contents

Statistical Analysis of Human Growth and Development (Paperback): Yin Bun Cheung Statistical Analysis of Human Growth and Development (Paperback)
Yin Bun Cheung
R1,434 Discovery Miles 14 340 Ships in 12 - 17 working days

Statistical Analysis of Human Growth and Development is an accessible and practical guide to a wide range of basic and advanced statistical methods that are useful for studying human growth and development. Designed for nonstatisticians and statisticians new to the analysis of growth and development data, the book collects methods scattered throughout the literature and explains how to use them to solve common research problems. It also discusses how well a method addresses a specific scientific question and how to interpret and present the analytic results. Stata is used to implement the analyses, with Stata codes and macros for generating example data sets, a detrended Q-Q plot, and weighted maximum likelihood estimation of binary items available on the book's CRC Press web page. After reviewing research designs and basic statistical tools, the author discusses the use of existing tools to transform raw data into analyzable variables and back-transform them to raw data. He covers regression analysis of quantitative, binary, and censored data as well as the analysis of repeated measurements and clustered data. He also describes the development of new growth references and developmental indices, the generation of key variables based on longitudinal data, and the processes to verify the validity and reliability of measurement tools. Looking at the larger picture of research practice, the book concludes with coverage of missing values, multiplicity problems, and multivariable regression. Along with two simulated data sets, numerous examples from real experimental and observational studies illustrate the concepts and methods. Although the book focuses on examples of anthropometric measurements and changes in cognitive, social-emotional, locomotor, and other abilities, the ideas are applicable to many other physical and psychosocial phenomena, such as lung function and depressive symptoms.

Reproductive Tourism in the United States - Creating Family in the Mother Country (Paperback): Lauren Jade Martin Reproductive Tourism in the United States - Creating Family in the Mother Country (Paperback)
Lauren Jade Martin
R1,232 Discovery Miles 12 320 Ships in 12 - 17 working days

This book examines the United States as a destination for international consumers of assisted fertility services, including egg donation, surrogacy, and sex selection. Based on interviews conducted with fertility industry insiders who market their services to an international clientele in three of the largest American hubs of the global fertility marketplace - New York City, Los Angeles, and San Francisco - and focusing on the providers rather than the consumers of assisted fertility services, the book shines a light on how professional ethics and norms, in addition to personal moralities, shape the practice of reproductive tourism.

Preimplantation Genetic Testing - Recent Advances in Reproductive Medicine (Hardcover): Darren K. Griffin, Gary L. Harton Preimplantation Genetic Testing - Recent Advances in Reproductive Medicine (Hardcover)
Darren K. Griffin, Gary L. Harton
R6,109 Discovery Miles 61 090 Ships in 12 - 17 working days

Preimplantation genetic testing (PGT) is now well established as a valuable treatment option for patients wishing to start or continue a family, for a range of indications from advanced maternal age to high risk of transmitting inherited disease. This text brings together contemporary thinking from international opinion leaders and will be an invaluable guide for practitioners in Reproductive Medicine wishing to keep pace with the latest developments and clinical data.

Statistical Analysis of Human Growth and Development (Hardcover, New): Yin Bun Cheung Statistical Analysis of Human Growth and Development (Hardcover, New)
Yin Bun Cheung
R3,206 Discovery Miles 32 060 Ships in 12 - 17 working days

Statistical Analysis of Human Growth and Development is an accessible and practical guide to a wide range of basic and advanced statistical methods that are useful for studying human growth and development. Designed for nonstatisticians and statisticians new to the analysis of growth and development data, the book collects methods scattered throughout the literature and explains how to use them to solve common research problems. It also discusses how well a method addresses a specific scientific question and how to interpret and present the analytic results. Stata is used to implement the analyses, with Stata codes and macros for generating example data sets, a detrended Q-Q plot, and weighted maximum likelihood estimation of binary items available on the book's CRC Press web page. After reviewing research designs and basic statistical tools, the author discusses the use of existing tools to transform raw data into analyzable variables and back-transform them to raw data. He covers regression analysis of quantitative, binary, and censored data as well as the analysis of repeated measurements and clustered data. He also describes the development of new growth references and developmental indices, the generation of key variables based on longitudinal data, and the processes to verify the validity and reliability of measurement tools. Looking at the larger picture of research practice, the book concludes with coverage of missing values, multiplicity problems, and multivariable regression. Along with two simulated data sets, numerous examples from real experimental and observational studies illustrate the concepts and methods. Although the book focuses on examples of anthropometric measurements and changes in cognitive, social-emotional, locomotor, and other abilities, the ideas are applicable to many other physical and psychosocial phenomena, such as lung function and depressive symptoms.

The Complete Guide to Male Fertility Preservation (Hardcover, 1st ed. 2018): Ahmad Majzoub, Ashok Agarwal The Complete Guide to Male Fertility Preservation (Hardcover, 1st ed. 2018)
Ahmad Majzoub, Ashok Agarwal
R3,911 Discovery Miles 39 110 Ships in 12 - 17 working days

This comprehensive, multidisciplinary guide provides an up-to-date presentation of fertility preservation techniques with male cancer patients and other challenging conditions. Divided into four thematic sections, part one provides an overview of the pathophysiologic processes interrelating cancer and its treatment with infertility and discusses different methods of sperm preservation and fertility outcomes in cancer patients. Part two then explores male fertility preservation in various non-cancerous conditions, such as immunosuppressed, hypogonadal and transgender patients. The fundamental principles of cryobiology and sperm optimization are covered in part three, which also offers essential building blocks for scientists to develop a sperm banking service and implement high standards of practice. The final section describes the current practices of male fertility preservation along with its psychological impact on patients, and extends beyond to future innovative methods-tissue preservation, xenografting and artificial gametes-being researched and implemented in this field. Fertility preservation among cancer patients and survivors is an evolving practice, which involves focused research and timely collaboration of professionals from related fields. The Complete Guide to Male Fertility Preservation is unique and original in its design and will appeal to a larger audience of andrologists, reproductive endocrinologists, urologists, embryologists, and all other clinicians practicing reproductive medicine and oncology.

Atlas of the Mammalian Ovary - Morphological Dynamics and Potential Role of Innate Immunity (Hardcover, 2012): Katharina... Atlas of the Mammalian Ovary - Morphological Dynamics and Potential Role of Innate Immunity (Hardcover, 2012)
Katharina Spanel-Borowski
R2,969 Discovery Miles 29 690 Ships in 10 - 15 working days

In the era of molecular biology, an atlas that allows a rapid understanding of the complexity of ovarian processes is urgently needed. In this book, the author draws upon her own research, conducted over the past three decades, to provide a unique compilation of high-quality illustrations that offer illuminating insights in a readily accessible form. The ovarian follicles, the corpus luteum, and the interstitial cortex are presented as precisely controlled homeostatic compartments. Physiologic cell death forms and leukocyte subtypes are clearly depicted, and the various steps in the ovulatory process are demonstrated in detail. Further topics addressed include the microvascular bed, the plasticity of intraovarian nerves as part of the remodelling processes in the polycystic and the menopausal ovary, and the role of cytokeratin-positive cells as messengers of innate immunity. This atlas will be a fascinating and informative resource for both trainees and more experienced professionals.

Manual of Embryo Culture in Human Assisted Reproduction (Paperback): Kersti Lundin, Aisling Ahlstroem Manual of Embryo Culture in Human Assisted Reproduction (Paperback)
Kersti Lundin, Aisling Ahlstroem
R1,299 R1,223 Discovery Miles 12 230 Save R76 (6%) Ships in 12 - 17 working days

Whilst assisted reproduction techniques (ART) have become increasingly successful and largely standardized, there is still only a partial understanding of what constitutes a 'true' embryo environment. Replicating the varying physiological conditions of the in-vivo environment that the embryo travels through in the in-vitro culture is still a major challenge in ART. This practical volume details how to organize and operate an IVF laboratory in order to mimic these conditions for successful embryo culture. Environments and equipment that are essential for running safe and efficient facilities such as maintaining good air quality and hygiene protocols, and utilizing an effective layout are covered in detail. Other chapters discuss the different consumables needed, optimal handling techniques and parameter monitoring systems, as well as recent advances in the area including artificial intelligence and automation. This is an indispensable guide to understanding the background science of culturing embryos, crucial to successful outcomes in ART.

How to Get Over Being Young - A Rough Guide to Midlife (Hardcover, Main): Charlotte Bauer How to Get Over Being Young - A Rough Guide to Midlife (Hardcover, Main)
Charlotte Bauer
R370 R296 Discovery Miles 2 960 Save R74 (20%) Ships in 5 - 10 working days

A deliciously funny and sage guide to midlife - an unscientific, flaws-and-all account of one woman's adventures and misadventures through the dark comedy of the wilderness years. Through her own experiences as a fifty-something woman, and those of her three sisters, her indomitable mum and rebellious auntie, Charlotte tackles the big questions every woman seeks answers to at this time of our lives - chiefly: How the hell am I going to get over being young in a world obsessed with youth? Written with warmth, wisdom and irreverence this guide to midlife is perfect for readers of Nora Ephron, Caitlin Moran and India Knight.

Notch Signaling in Embryology and Cancer (Hardcover, 2012): Joerg Reichrath, Sandra Reichrath Notch Signaling in Embryology and Cancer (Hardcover, 2012)
Joerg Reichrath, Sandra Reichrath
R5,696 Discovery Miles 56 960 Ships in 10 - 15 working days

The goal of this volume is to comprehensively cover a highly readable overview on our present knowledge of the role of Notch signalling for embryology and cancer, with a focus on new findings in molecular biology. Topics that are discussed in-depth by leading researchers and clinicians range from the newest findings in cellular and molecular pathology to new concepts for prophylaxis and treatment of cancer. Experts in the field as well as scientists and health care professionals not intimately involved in these specialized areas are provided with the most significant and timely information related to these topics. It is the aim of this book to summarize essential up-to-date information for every clinician or scientist interested in the role of Notch signalling in embryology and cancer. We hope that this volume will be adopted as the standard text in this area of science and will stimulate new interest in the role of Notch signalling for embryology and cancer. We further hope that this compendium will serve as both a source for current researchers and a guide to stimulate and assist those in related disciplines to enter this exciting field of research.

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