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Books > Medicine > Clinical & internal medicine > Geriatric medicine
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Cellular Ageing and Replicative Senescence (Hardcover, 1st ed. 2016)
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Cellular Ageing and Replicative Senescence (Hardcover, 1st ed. 2016)
Series: Healthy Ageing and Longevity, 4
Expected to ship within 10 - 15 working days
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This book covers the origins and subsequent history of research
results in which attempts have been made to clarify issues related
to cellular ageing, senescence, and age-related pathologies
including cancer. Cellular Ageing and Replicative Senescence
revisits more than fifty-five years of research based on the
discovery that cultured normal cells are mortal and the
interpretation that this phenomenon is associated with the origins
of ageing. The mortality of normal cells and the immortality of
cancer cells were also reported to have in vivo counterparts. Thus
began the field of cytogerontology. Cellular Ageing and Replicative
Senescence is organized into five sections: history and origins;
serial passaging and progressive ageing; cell cycle arrest and
senescence; system modulation; and recapitulation and future
expectations. These issues are discussed by leading thinkers and
researchers in biogerontology and cytogerontology. This collection
of articles provides state-of-the-art information, and will
encourage students, teachers, health care professionals and others
interested in the biology of ageing to explore the fascinating and
challenging question of why and how our cells age, and what can and
cannot be done about it.
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