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Books > Medicine > Pre-clinical medicine: basic sciences > Human reproduction, growth & development
Founded in 1914, the Department of Embryology of the Carnegie Institution of Washington has made an unparalleled contribution to the biological understanding of embryos and their development. Originally much of the research was carried out through experimental embryology, but by the second half of the twentieth century, tissue and cell cultures were providing histological information about development, and biochemistry and molecular genetics have taken center stage. This final volume in a series of five histories of the Carnegie Institution of Washington provides a history of embryology and reproductive biology spanning a hundred years. It provides important insights into the evolution of both scientific ideas and the public perception of embryo research, concluding with a reflection on current debates.
This practical 2003 handbook provides an extremely comprehensive and highly illustrated guide to micromanipulation techniques in assisted conception in a clinical setting. It includes detailed, illustrated descriptions of all the common micromanipulation systems currently in use in IVF laboratories around the world and clearly explains how to optimise their successful use. The volume covers state-of-the-art techniques including intracytoplasmic sperm injection (ICSI), and procedures such as assisted hatching and the blastomere biopsy (for preimplantation genetic diagnosis PGD). Valuable information on troubleshooting the potential mechanical and technical difficulties that can arise is provided to help all the practitioners of these techniques, including trainee embryologists and consultant obstetricians, and technicians and scientists involved in animal transgenesis and cloning. It will undoubtedly be of immense value to all doctors and scientists working with assisted reproductive technologies.
This new edition provides a much-needed reference book to accommodate emerging and expanding knowledge in fertility preservation, the rapidly growing field of reproductive medicine associated with advances in oncology. Written by a team of world-leading experts in the field and comprehensive in its scope, the book covers the full range of techniques and scientific concepts in detail. It opens with an introduction to fertility preservation in both cancer and non-cancer patients, followed by fertility preservation strategies in males and females, including medical/surgical procedures, ART, cryopreservation and transplantation of ovarian tissue, and in-vitro follicle culture. Concluding chapters address new technologies, as well as ethical, legal and religious issues. The book has been thoroughly updated, includes additional contributors, and now provides greater focus on practical and clinically relevant issues. Richly illustrated throughout, this is a key resource for clinicians specializing in reproductive medicine, gynecology, oncology, hematology, endocrinology and infertility.
How the fear of malpractice affects mothers and reproductive choices Giving birth is a monumental event, not only in the personal life of the woman giving birth, but as a medical process and procedure. In The Business of Birth, Louise Marie Roth explores the process of giving birth, and the ways in which medicine and law interact to shape maternity care. Focusing on the United States, Roth explores how the law creates an environment where medical providers, malpractice attorneys, and others limit women's rights and choices during birth. She shows how a fear of liability risk often drives the decision-making process of medical providers, who prioritize hospital efficiency over patient safety, to the detriment of mothers themselves. Ultimately, Roth advocates for an approach that protects the reproductive rights of mothers. A comprehensive overview, The Business of Birth provides valuable insight into the impact of the law on mothers, medical providers, maternity care practices, and others in the United States.
This comprehensive review of the factors that affect the harvesting and preparation of oocytes and the management of embryos will allow practitioners to make evidence-based decisions for successful IVF. The book reviews and re-considers the value of strategies and outcomes in the management of fertility and conception rates, centred on the production of oocytes, and successful development of the embryo. Authored by leading experts in the field, chapters engage with treatments and strategies that affect the production of oocytes and embryos, optimizing outcomes in the management of female fertility, conception rates, and live births. This vital guide covers controlled ovarian hyperstimulation, the role of AMH in determining ovarian reserve, and primary stimulation agents and the use of adjuncts. Integral for all clinicians and embryologists working in reproductive medicine units, readers are provided with evidence-based, comprehensive advice and review of all factors affecting the management of oocytes and the embryo that are vital for successful IVF cycles.
IVF is now established worldwide as a clinical service. Units are striving to improve their success rates, and many treatments are being advocated as 'yet another breakthrough'. The purpose of this book is to help clinicians to evaluate each of these new treatments. Each chapter is written by a recognized international expert in the field and the chapters are short and succinct, summarizing the latest evidence-based information for each topic and treatment. Sections cover patient selection and preparation, the role of AIH before IVF, stimulation, monitoring, laboratory techniques, embryo transfer, ancillary treatments and assessment of results. How to Improve your ART Success Rates: An Evidence-Based Review of Adjuncts to IVF is essential reading for all clinicians working with infertility and assisted reproduction, and is also a valuable addition to any medical library.
Offering expert, practical guidance through the decision-making process,Differential Diagnoses in Surgical Pathology: Gynecologic Tract, Second Edition, by Drs. Russell Vang, Anna Yemelyanova, and Jeffrey D. Seidman, helps you systematically solve tough diagnostic challenges in gynecologic pathology and arrive at a correct diagnosis between commonly confused entities. In this fully revised edition, lesions are presented side by side for easy comparison, with clinical and pathological findings in short outline format followed by several full-color images. In addition to illustrating and discussing the classical features of these entities, the authors emphasize atypical features that can complicate diagnoses. Provides side-by-side comparisons for each major differential diagnosis—more than 170 in all— helping you distinguish between commonly confused lesions of the gynecologic tract Contains more than 1,500 full-color photographs that depict the features of each entity and cover all major differential diagnoses in this challenging area Offers up-to-date coverage of the vulva and vagina, cervix, endometrial epithelial lesions, uterine pure mesenchymal and mixed epithelial-mesenchymal lesions, the ovary, peritoneum/omentum, fallopian tube and paratubal region, and gestational trophoblastic disease Ideal for practicing pathologists, pathologists in training, residents, and medical students  Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.Â
Welcomed as liberation and dismissed as exploitation, egg freezing (oocyte cryopreservation) has rapidly become one of the most widely-discussed and influential new reproductive technologies of this century. In Freezing Fertility, Lucy van de Wiel takes us inside the world of fertility preservation—with its egg freezing parties, contested age limits, proactive anticipations and equity investments—and shows how the popularization of egg freezing has profound consequences for the way in which female fertility and reproductive aging are understood, commercialized and politicized. Beyond an individual reproductive choice for people who may want to have children later in life, Freezing Fertility explores how the rise of egg freezing also reveals broader cultural, political and economic negotiations about reproductive politics, gender inequities, age normativities and the financialization of healthcare. Van de Wiel investigates these issues by analyzing a wide range of sources—varying from sparkly online platforms to heart-breaking court cases and intimate autobiographical accounts—that are emblematic of each stage of the egg freezing procedure. By following the egg’s journey, Freezing Fertility examines how contemporary egg freezing practices both reflect broader social, regulatory and economic power asymmetries and repoliticize fertility and aging in ways that affect the public at large. In doing so, the book explores how the possibility of egg freezing shifts our relation to the beginning and end of life.
'Essential reading for anyone who has been through the sadness of a lost pregnancy' The Times 'Sensitive and insightful' Sunday Times Style 'This book will be a godsend to any woman going through the murky devastation that is called miscarriage but feels like something else entirely: the loss of a baby' Ariel Levy 'A compassionate, nuanced book that does this very complicated grief justice' Pandora Sykes 'This book will be the friend to hold your hand while you navigate your own pathway of grief. I'm so glad it's here' Elle Wright Beyond Grief also contains interviews with experts and other women who have experienced losses of their own, including Elizabeth Day, Leandra Medine Cohen, Melissa Odabash, Jools Oliver, Alexandra Stedman and Latham Thomas. Pippa Vosper tragically lost her son Axel in 2017, when she was five months pregnant, and has since written about miscarriage and baby loss online and in a series of pieces for Vogue. Beyond Grief: Navigating the Journey of Pregnancy and Baby Loss is the book she wishes had been available when her son died. It covers every aspect of pregnancy and baby loss at any stage, from the practical to the emotional, with advice from experts and stories from women who have been through it themselves. Beyond Grief offers both an inclusive perspective and a guiding hand to anyone who has experienced any kind of pregnancy loss, as well as those who are trying to support them through it.
Forms, Souls, and Embryos allows readers coming from different backgrounds to appreciate the depth and originality with which the Neoplatonists engaged with and responded to a number of philosophical questions central to human reproduction, including: What is the causal explanation of the embryo's formation? How and to what extent are Platonic Forms involved? In what sense is a fetus 'alive,' and when does it become a human being? Where does the embryo's soul come from, and how is it connected to its body? This is the first full-length study in English of this fascinating subject, and is a must-read for anyone interested in Neoplatonism or the history of medicine and embryology.
Preimplantation genetic testing (PGT) is now well established as a valuable treatment option for patients wishing to start or continue a family, for a range of indications from advanced maternal age to high risk of transmitting inherited disease. This text brings together contemporary thinking from international opinion leaders and will be an invaluable guide for practitioners in Reproductive Medicine wishing to keep pace with the latest developments and clinical data.
"Introducing the only clinically proven program--steeped in ancient
Chinese healing traditions--that has enabled hundreds of infertile
couples to conceive.
Implantation is a complex phenomenon, still not thoroughly understood, involving the embryo and the endometrium. Successful implantation is considered to stem from an efficient combination of various embryo and/or maternal factors. Repeated failure of any of these factors or of their combination might decrease the chance of implantation and eventually lead to recurrent implantation failure. Despite technological advances, only about a quarter of In Vitro Fertilization procedures will result in live birth, leading many couples to experience multiple failures. This text from international experts explores the various factors at play and offers a helpful summary of the state of knowledge to help guide clinicians in their management of this complex and important problem. Contents: What is Recurrent Implantation Failure? * The psychosocial aspects of recurrent implantation failure * The role of life-style factors in RIF * Endocrine causes of recurrent implantation failure * Congenital uterine anomalies and recurrent implantation failure * Immunological causes of recurrent implantation failure * Acquired uterine conditions, reproductive surgery, and RIF? * Thrombophilia: diagnosis and management in women with recurrent implantation failure * Andrological causes of RIF * Diagnostic evaluation of RIF? (Modalities and algorithm) * Optimizing embryo culture for RIF? * Optimizing endometrial receptivity for patients with recurrent implantation failure: The role of progesterone on the day of triggering final oocyte maturation * Is there a role of follicular phase LH and E2 on the day of triggering final oocyte maturation for embryo implantation? * Manipulating the endometrium: Can RIF be managed by inducing endometrial inflammation or by the use of novel research therapies * The embryo in RIF: Genetic selection and strategies for improving its implantation potential * Is oocyte donation efficient in patients with RIF? * Sperm donation and RIF? * Optimizing embryo transfer technique for RIF management * Proposed management of patients with recurrent implantation failure and directions for future research * When should patients abandon treatment?
The fourth edition of this book updates and elaborates on the seven dimensions of maternal emotional health that have significant impact on delivery, postpartum adaptation, infant health, and early childhood development. Supported by the authors' original research and interviews, the book provides readers with an analysis of the role of these core functions throughout pregnancy, as well as practical materials for use with pregnant clients in the form of assessment instruments and evidence-based interventions for promoting positive development. The book provides a theoretical framework with rationales for the seven psychosocial dimensions, therapeutic and counseling intervention strategies to improve adaptive development in each of the seven psychosocial dimensions, findings specific to women in diverse cultural groups, a chapter devoted to women in the military and military spouses, and discussion of salient issues of pregnancy, including physical changes, body image, intimacy, trust, and ambivalence. The book focuses on the seven dimensions of maternal prenatal emotional health: Acceptance of the pregnancy. Motivation and preparation for motherhood. Relationship with husband/partner. Relationship with her own mother. Preparation for labor. Sense of control in labor Self-Esteem and Well-Being in labor. Psychosocial Adaptation to Pregnancy is a significant addition to the psychosocial assessment literature, a needed resource for clinical and health psychologists, clinical social workers, marriage and family therapists, professional counselors, midwives, and obstetrical nurses. It is also adaptable to undergraduate and graduate courses in maternal reproductive health and obstetrical nursing.
Period positivity starts with asking questions. This informative, irreverent, and absorbing book covers all your period-related questions - why they're taboo (and needn't be) and how to navigate the whole bleeding thing, from first periods to fertility, euphemisms to uteruses, menstrual products to menopause. Let's get period positive. It's about bloody time. Feel your best at any time of the month! This science-backed menstruation book is full of good advice and friendly tips to give you the tools to re-frame your thinking and learn to love your cycle. This frank, funny, and fascinating menstruation guide from Period Positive movement founder and menstrual researcher, Chella Quint's offers: - A practical, science-backed guide to your period with arresting infographics, and anatomical diagrams - Answers to all your period-related questions, exploring topics like the functions and effects of hormones, when periods "normal" or "abnormal," hormonal birth control, sex, fertility, pregnancy - Explanations of common female health conditions such as PCOS and endometriosis Light or heavy, early or late, painful or painfully bad timing - periods can be a nightmare. With its beautiful visuals and question and answer format, Be Period Positive provides practical advice on managing the common symptoms most women have during their period - from easing cramps to using a menstrual cup, coming off the pill and managing PMS. Find answers to the common period myths like whether your menstrual cycle is linked to the moon or if period syncing is a thing. Explore how periods evolved and what is going on in your body to deepen your understanding of your cycle. This period positive book includes sections that will help you "hack your period". Learn how adapting your diet, exercise, and other strategies can help you manage hormonal fluctuations' physical and emotional effects. Learn how to recognise when you're at your most receptive, creative, and vulnerable so that you can get the best out of every stage of your cycle.
In the 1960s thousands of poor women of color on the (post)colonial French island of Reunion had their pregnancies forcefully terminated by white doctors; the doctors operated under the pretext of performing benign surgeries, for which they sought government compensation. When the scandal broke in 1970, the doctors claimed to have been encouraged to perform these abortions by French politicians who sought to curtail reproduction on the island, even though abortion was illegal in France. In The Wombs of Women-first published in French and appearing here in English for the first time-Francoise Verges traces the long history of colonial state intervention in black women's wombs during the slave trade and postslavery imperialism as well as in current birth control politics. She examines the women's liberation movement in France in the 1960s and 1970s, showing that by choosing to ignore the history of the racialization of women's wombs, French feminists inevitably ended up defending the rights of white women at the expense of women of color. Ultimately, Verges demonstrates how the forced abortions on Reunion were manifestations of the legacies of the racialized violence of slavery and colonialism.
As the older population in the United States is becoming more racially and ethnically diverse, it is important to understand the characteristics, the potential, and the needs of this population. In this new and fully revised edition of Aging and Diversity, Chandra Mehrotra and Lisa Wagner address key topics in diversity and aging, discussing how the aging experience is affected by not only race and ethnicity but also gender, religious affiliation, social class, rural-urban community location, and sexual orientation and gender identity. Taking this broad view of human diversity allows the authors to convey some of the rich complexities facing our aging population - complexities that provide both challenges to meet the needs of a diverse population of elders and opportunities to learn how to live in a pluralistic society. Mehrotra and Wagner present up-to-date knowledge and scholarship about aging and diversity in a way that engages readers in active learning, placing ongoing emphasis on developing readers' knowledge and skills, fostering higher order thinking, and encouraging exploration of personal values and attitudes.
In The Menopause Manifesto internationally renowned, New York Times
bestselling author Dr Jen Gunter brings you empowerment through
knowledge by countering stubborn myths and misunderstandings about
menopause with hard facts, real science, fascinating historical
perspective and expert advice.
Filled with practical, reassuring information, this essential guide will revolutionise how women experience menopause - including how their lives can be even better for it!
Essential Reproduction provides an accessible account of the fundamentals of reproduction within the context of cutting-edge knowledge and examples of its application. The eighth edition of this internationally best-selling title provides a multidisciplinary approach integrating anatomy, physiology, genetics, behaviour, biochemistry, molecular biology and clinical science, to give thorough coverage of the study of mammalian reproduction. Key features: Contains discussion of the latest on conceptual, informational and applied aspects of reproduction New pedagogical features such as clinical case studies at the end of each chapter Better use of boxed material to improve separation of narrative text from ancillary information Highlighted key words for ease of reference relate to summary of key points Introduction now split into two sections Expanded content in Fetal challenges, and Society and reproduction Substantial rearrangement and updating in Making sperm, Controlling fertility, and Restoring fertility
At a moment when reproduction is increasingly politicized, this volume explores the breadth of contemporary research on reproduction from the perspective of medical sociology, illuminating the lived experience of reproduction and offering insights to inform sociology and health policy. Reproduction, Health, and Medicine elucidates the tensions and contradictions between the normal physiologic processes of pregnancy and birth and the sociocultural beliefs, values, and arrangements that shape how we experience these biological phenomena. Investigating a range of reproductive events and experiences, including pregnancy, birth, abortion and fertility planning, the volume advances our understanding of how lay people and professionals make cultural meaning out of these processes in diverse settings. The chapters highlight how studies of reproduction, health, and medicine interface with core sociological concepts such as stratification, inequality, intersectionality, family and kinship, risk, and social control, and how experiences of reproduction are shaped by gender, race, class, sexuality and citizenship, as well as culture, health care systems, and health politics.
Although impotence may be the most widely recognized manifestation of male sexual dysfunction, many other forms of sexual disorders do not involve the erectile mechanism, from deficiencies of desire to disturbances in ejaculatory function to the failure of detumescence. With such a myriad-and often co-existing-number of disorders, the successful treatment of male sexual dysfunction requires not only a thorough understanding of the underlying physiology and pathophysiology, but also the coordinated efforts of multiple specialties, including endocrinology, andrology, urology, radiology, sex therapy, and even sometimes psychiatry, cardiology, or oncology. Male Sexual Dysfunction: Pathophysiology and Treatment presents the collective expertise of more than 60 international authorities in a single landmark text. From foundations in the anatomy of the male genital tract to the latest neuroimaging data, readers will appreciate the comprehensive information detailing the tremendous advances made in the delineation of sexual function and its disorders as well as the expert descriptions of practical and cost-effective medical, surgical, and psychological strategies for the treatment of all forms of male sexual dysfunction.
Management of Infertility: A Practical Approach offers an accurate and complete reference for the management of infertility and a robust step-by-step guide for assisted reproduction technologies (ARTs), including how to plan, design and organize a clinical setting and laboratory. The book also provides an evidence-based, complete and practical description of the available methods for diagnosis and management of male and female infertility. This will be an ideal resource for researchers, students and clinicians who want to gain complete knowledge about both basic and advanced information surrounding the diagnosis and management of infertility and related disorders.
Spermatogenesis is a tightly regulated cellular renovation and differentiation process. It consists of self-renewal and differentiation of spermatogonial stem cells (SSCs), spermatocytic meiosis and spermiogenesis; each of these processes is essential to the continuous, successful production of male gametes. During spermiogenesis, haploid spermatids undergo extensive cellular, molecular and morphological changes, including acrosome biogenesis, flagellum development, cytoplasmic reorganization and chromatin condensation. These changes ultimately result in mature spermatozoa with an acrosome-covered head and motile tail. In this book, Chapter One summarizes the progress that has been made in understanding the molecular mechanisms underlying acrosome biogenesis, and the authors discuss the potential directions of future investigations of this process. Chapter Two briefly addresses the basics of spermatogenesis and the synthesis of ncRNAs, and then the authors discuss the recent progress in understanding of the functions of miRNAs, endo-siRNAs, piRNAs and lncRNAs in the regulation of spermatogenesis. Chapter Three provides a review of the current literature on testicular immunoregulation and its underlying mechanisms, along with its effect on testicular functions.
Adopts an "issues approach" to teaching introductory biology Up-to-date on relevant topics like climate change, CRISPR, new hominids, and new cancer therapies Suitable for both a majors and non-majors course More succinct for ease in teaching and more affordable for students A large suite of student resources, such as questions to enable self-testing, simulations of key processes to aid learning, web links to encourage further reading Instructor resources to use in teaching, such as PowerPoint slides with figures from the book, activity and assignment ideas, and comprehensive lesson plans |
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