The first volume in this new series from The Center for the Study of Child and Adolescent Development at The Pennsylvania State University focuses on the relationship between the biological stress circuits and the behavioral concomitants to stress in animals and humans. The participants at this conference, a tribute to Dean Evan G. Pattishall, Jr., discuss the developmental implications of their work in relation to the periods of infancy, childhood, and adolescence. For professionals, clinicians, and researchers in clinical, developmental, experimental, and health psychology, behavioral medicine, psychiatry, psychotherapy, and the neurosciences.

In their desperate quest for conception, thousands of infertile couples from around the world travel to the global in vitro fertilization (IVF) hub of Dubai. In Cosmopolitan Conceptions Marcia C. Inhorn highlights the stories of 220 "reprotravelers" from fifty countries who sought treatment at a "cosmopolitan" IVF clinic in Dubai. These couples cannot find safe, affordable, legal, and effective IVF services in their home countries, and their stories offer a window into the world of infertility-a world that is replete with pain, fear, danger, frustration, and financial burden. These hardships dispel any notion that traveling for IVF treatment is reproductive tourism. The magnitude of reprotravel to Dubai, Inhorn contends, reflects the failure of countries to meet their citizens' reproductive needs, which suggests the necessity of creating new forms of activism that advocate for developing alternate pathways to parenthood, reducing preventable forms of infertility, supporting the infertile, and making safe and low-cost IVF available worldwide.

The Business of Being Made is the first book to critically analyze assisted reproductive technologies (ARTs) from a transdisciplinary perspective integrating psychoanalytic and cultural theories. It is a ground-breaking collection exploring ARTs through diverse methods including interview research, clinical case studies, psychoanalytic based ethnography, and memoir. Gathering clinicians and researchers who specialize in this area, this book engages current research in psychoanalysis, sociology, anthropology, philosophy and debates in feminist, queer and cultural theory about affect, temporality, and bodies. With psychoanalysis as its fulcrum, The Business of Being Made explores the social constructions and personal experiences of ARTs. Katie Gentile frames the cultural context, exploring the ways ARTs have become a complex form of playing with time, attempting to manufacture a hopeful future in the midst of growing global uncertainty. The contributors then present a range of varied experiences related to ARTs, including: Interviews with women and men undergoing ARTs; A psychoanalytic memoir of male infertility; Clinical research and work with transgender, gay and lesbian patients creating new Oedipal constellations, the experiences of LBGTQ people within the medical system and the variety of families that emerge; Research on the experiences of egg donors (now central to the business of ARTs) and a corresponding clinical case study of successful egg donation; The experiences of ongoing failure which is the often unacknowledged for ART procedures; How and when people choose to stop using ARTs; A psychoanalytic ethnography of a neonatal intensive care unit populated in part with the babies created through these technologies and their parents, haggard and in shock after years of failed attempts. Full of original material, The Business of Being Made conveys the ambivalence of these technologies without simplifying their complicated consequences for the bodies of individuals, the family, cultures, and our planet. This book will be relevant to clinicians, medical and psychological personnel working in assisted reproductive technologies and infertility, as well as academics working in the fields of sociology, literature, queer and feminist theories and at the intersections of cultural, critical and psychoanalytic theories.

The Business of Being Made is the first book to critically analyze assisted reproductive technologies (ARTs) from a transdisciplinary perspective integrating psychoanalytic and cultural theories. It is a ground-breaking collection exploring ARTs through diverse methods including interview research, clinical case studies, psychoanalytic based ethnography, and memoir. Gathering clinicians and researchers who specialize in this area, this book engages current research in psychoanalysis, sociology, anthropology, philosophy and debates in feminist, queer and cultural theory about affect, temporality, and bodies. With psychoanalysis as its fulcrum, The Business of Being Made explores the social constructions and personal experiences of ARTs. Katie Gentile frames the cultural context, exploring the ways ARTs have become a complex form of playing with time, attempting to manufacture a hopeful future in the midst of growing global uncertainty. The contributors then present a range of varied experiences related to ARTs, including: Interviews with women and men undergoing ARTs; A psychoanalytic memoir of male infertility; Clinical research and work with transgender, gay and lesbian patients creating new Oedipal constellations, the experiences of LBGTQ people within the medical system and the variety of families that emerge; Research on the experiences of egg donors (now central to the business of ARTs) and a corresponding clinical case study of successful egg donation; The experiences of ongoing failure which is the often unacknowledged for ART procedures; How and when people choose to stop using ARTs; A psychoanalytic ethnography of a neonatal intensive care unit populated in part with the babies created through these technologies and their parents, haggard and in shock after years of failed attempts. Full of original material, The Business of Being Made conveys the ambivalence of these technologies without simplifying their complicated consequences for the bodies of individuals, the family, cultures, and our planet. This book will be relevant to clinicians, medical and psychological personnel working in assisted reproductive technologies and infertility, as well as academics working in the fields of sociology, literature, queer and feminist theories and at the intersections of cultural, critical and psychoanalytic theories.

Based on the author's fieldwork at assisted conception clinics in England in the mid-1990s, this is the first ethnographic study of the new procreative practices of anonymous ova and embryo donation. Giving voice to both groups of women participating in the demanding donation experience - the donors on the one side and the ever-hopeful IVF recipients on the other - Konrad shows how one dimension of the new reproductive technologies involves an unfamiliar relatedness between nameless and untraceable procreative strangers. Offsetting informants' local narratives against traditional Western folk models of the 'sexed' reproductive body, the book challenges some of the basic assumptions underlying conventional biomedical discourse of altruistic donation that clinicians and others promote as "gifts of life." It brings together a wide variety of literatures from social anthropology, social theory, cultural studies of science and technology, and feminist bioethics to discuss the relationship between recent developments in biotechnology and changing conceptions of personal origins, genealogy, kinship, biological ownership and notions of bodily integrity.

This practical handbook provides detailed guidelines on prescribing drugs in all classes and for a wide variety of diseases and disorders during pregnancy, with numerous boxes and tables to assist understanding. CONTENTS: Introduction to Drugs in Pregnancy * Antimicrobials during Pregnancy: Bacterial, Viral, Fungal, and Parasitic Indications * Cardiovascular Drugs during Pregnancy * Endocrine Disorders, Contraception, and Hormone Therapy during Pregnancy: Embryotoxic versus Fetal Effects * Antiasthma Agents during Pregnancy * Anesthetic Agents and Surgery during Pregnancy * Antineoplastic Drugs during Pregnancy * Analgesics during Pregnancy * Anticonvulsant Drugs during Pregnancy * Psychotropic Use during Pregnancy * Antihistamines, Decongestants, and Expectorants during Pregnancy * Nutritional and Dietary Supplementation during Pregnancy * Use of Dermatologics during Pregnancy * Drug Overdoses during Pregnancy * Miscellaneous Drugs during Pregnancy: Tocolytics, Immunosuppressants, and Biologic Therapeutics * Substance Abuse during Pregnancy * Online Support Material

One in six couples around the world experience infertility. Before undertaking expensive and intrusive assisted reproductive treatment such as in vitro fertilization, many seek advice from their physicians or dietitians on what foods and supplements might enhance their fertility. But health practitioners are often ill equipped to provide dietary recommendations in a scientifically based manner. Nutrition, Fertility, and Human Reproductive Function provides a comprehensive guide to clinicians on how they can best advise their patients to optimise fertility and reproductive function through optimal nutrition. Taking a holistic or "whole-of-life" approach, the book reviews the role of nutrition in human fertility and explores its effect on male and female reproductive physiology. Problem-orientated topics are arranged in chapters that each cover a specific clinical topic of interest, allowing easy reference by the practicing clinician. From the female perspective, the book covers the role of nutrition on essential reproductive processes such as ovulation, early embryo development, implantation, and sexual function, together with nutrition's influence on the duration of the reproductive life span. In the male context, it examines the effect of nutrition on hormone and sperm production as well as sexual function. The book also includes information on evidence-based complementary health approaches such as Traditional Chinese Medicine (TCM) and naturopathy. This book draws on the wide experience of several respected leaders in clinical nutrition who combine research expertise with clinical insight. The information contained herein will enable clinicians to make the best recommendations for their patients for optimising fertility.

This book explores the cultural history of embryology in Tibet, in culture, religion, art and literature, and what this reveals about its medicine and religion. Filling a significant gap in the literature this is the first in-depth exploration of Tibetan medical history in the English language. It reveals the prevalence of descriptions of the development of the human body - from conception to birth - found in all forms of Tibetan religious literature, as well as in medical texts and in art. By analysing stories of embryology, Frances Garrett explores questions of cultural transmission and adaptation: How did Tibetan writers adapt ideas inherited from India and China for their own purposes? What original views did they develop on the body, on gender, on creation, and on life itself? The transformations of embryological narratives over several centuries illuminate key turning points in Tibetan medical history, and its relationship with religious doctrine and practice. Embryology was a site for both religious and medical theorists to contemplate profound questions of being and becoming, where topics such as pharmacology and nosology were left to shape secular medicine. The author argues that, in terms of religion, stories of human development comment on embodiment, gender, socio-political hierarchy, religious ontology, and spiritual progress. Through the lens of embryology, this book examines how these concerns shift as Tibetan history moves through the formative 'renaissance' period of the twelfth through to the seventeenth centuries.

Lax federal oversight, high technology resources, privatized health care, a pluralist population, and a commitment to professional autonomy make the United States an ideal host for reproductive tourists. Those who are in possession of enough material resources and political savvy can subvert their countries' norms and laws regarding reproductive technologies, in effect becoming procreative outlaws. This book examines the United States as a destination for international consumers of assisted fertility services, including egg donation, surrogacy, and sex selection. It is based on interviews conducted with fertility industry insiders who market their services to an international clientele in three of the largest American hubs of the global fertility marketplace - New York City, Los Angeles, and San Francisco. By focusing on the providers rather than the consumers of assisted fertility services, the book shines a light on how professional ethics and norms, in addition to personal moralities, shape the practice of reproductive tourism.

There has been an increasing interest in the application of dynamical systems to the study of development over the last decade. The explosion of the dynamical systems framework in the physical and biological sciences has opened the door to a new Zeitgeist for studying development. This appeal to dynamical systems by developmentalists is natural given the intuitive links between the established fundamental problems of development and the conceptual and operational scope of nonlinear dynamical systems. This promise of a new approach and framework within which to study development has led to some progress in recent years but also a growing appreciation of the difficulty of both fully examining the new metaphor and realizing its potential. Divided into 4 parts, this book is a result of a recent conference on dynamical systems and development held at Pennsylvania State University. The first 3 parts focus on the content domains of development that have given most theoretical and empirical attention to the potential applications of dynamical systems--physical growth and movement, cognition, and communication. These parts show that a range of nonlinear models have been applied to a host of developmental phenomena. Part 4 highlights two particular methodological issues that hold important implications for the modeling of developmental phenomena with dynamical systems techniques.

There are common midlife events that account for the special narcissistic vulnerabilities of this period of life, and Eda Goldstein ably reviews these events and the theoretical perspectives commonly brought to bear on them. In When the Bubble Bursts, however, Goldstein's special concern is those individuals who come to midlife with heightened narcissistic vulnerabilities that make the navigation of this stage of life more difficult still. In understanding the latter such patients and devising a treatment approach appropriate to their "self" issues, Goldstein adopts a broadly self-psychological frame of reference. It is a matter, she finds again and again, of understanding how current stressors frustrate healthy self needs and trigger narcissistic vulnerabilities. Self-psychologically informed treatment, which, in Goldstein's pragmatic purview, embraces modalities that are, to varying degrees, supportive, psychodynamic, and psychoanalytic, reworks and strengthens self structures in helping patients find new ways of affirming their sense of self. Her substantive case studies, which accompany the reader through all the chapters in her study, draw on personal and supervisory experiences to illustrate crucial foci of the treatment process with a range of midlife patients in psychotherapy. Eda Goldstein presents a study that comprises an admirable blend of theoretical astuteness, clinical wisdom, and personal honesty. Her clinical study of midlife narcissistic pathology is bracketed by her balanced discussion of theoretical perspectives on adult development and her concluding consideration of the countertransference issues elicited by midlife patients in midlife therapists. When the Bubble Bursts is an edifying contribution to the literatures of psychodynamic psychotherapy, self psychology, and adult development.

The Last Years of Long Lives is a unique account of that period of old age which precedes death. Based on 400 complete individual histories and covering a twenty-year period, it looks at the experiences of people over eighty years old in three important areas: disability, family life and health care. Using the life-course approach to research, it reveals rich data about the contributions of formal and informal care and how life expectancy and experiences of disability interact with experiences of care. The reader is invited to conceptualise these phenomena as processes in continuous time - processes that are sometimes long and complex, sometimes short and simple - and learns about the four types of disability career before death. At the same time, the author presents a three-stage model of informal care and examines the main patterns of formal service use. The Last Years of Long Lives presents a new way of looking at old age for students, researchers, practitioners and policy makers and gives a comprehensive picture of what has been called 'the fourth age'.

This book explores how conditions for childbearing are changing in the 21st century under the impact of new biomedical technologies. Selective reproductive technologies (SRTs) - technologies that aim to prevent or promote the birth of particular kinds of children - are increasingly widespread across the globe. Wahlberg and Gammeltoft bring together a collection of essays providing unique ethnographic insights on how SRTs are made available within different cultural, socio-economic and regulatory settings and how people perceive and make use of these new possibilities as they envision and try to form their future lives. Topics covered include sex-selective abortions, termination of pregnancies following detection of fetal anomalies during prenatal screening, the development of preimplantation genetic diagnosis techniques as well as the screening of potential gamete donors by egg agencies and sperm banks. This is invaluable reading for scholars of medical anthropology, medical sociology and science and technology studies, as well as for the fields of gender studies, reproductive health and genetic disease research.

Each patient seeking assisted reproduction has a unique set of circumstances that affects the outcome of treatment. Particularly challenging are those patients with pre-existing medical conditions or those receiving medical therapies that may impact the safety and success of their IVF treatments. Prior identification and preparation of the patient at increased risk of complications will enable the clinician to avoid problems in advance, anticipate the necessary management, and optimize outcomes. A new expanded edition of the prize-winning text IVF in the Medically Complicated Patient: A Guide to Management, Second Edition provides a readily accessible, authoritative, and didactic source of information to aid clinicians in this important field.

For centuries people have been puzzled by the inevitability of human aging. For most of the second half of the twentieth century aging remained a mystery, or an unsolved biological problem. At the end of the 20th century a remarkable scientific discovery emerged. It was not a single discovery in the usual sense, because it was based on a series of important interconnected insights over quite a long period of time. These insights made it possible for the very first time to understand the biological reasons for aging in animals and man. It can already be said, however, that the many observations and insights that explain aging will not be accepted as established knowledge for a long time. The field is still full of scientists, and non-scientists, who are just happy to go on speculating about the mystery of aging.

This latest addition to the "Fast Facts" series, authored by nursing luminary Judith Herrman, is a pithy, authoritative guide to adolescent health designed specifically for nurses at all levels and other health care professionals. It is the only book written for nurses and other health care professionals who work with adolescents in schools, community agencies, neighborhoods, and other settings, and contains the resources needed to best serve this population. Designed to provide speedy information retrieval, the guide describes a broad spectrum of health and health care issues particular to adolescents, reviews current data, explores behaviors and risk factors, and addresses nursing implications for treatment. Framed in a positive perspective of adolescence, the book also includes suggestions for working and communicating effectively with teens.

Chapters are consistently organized according to the domain model, a whole-person health model comprised of six pillars: physical, intellectual, sexual, spiritual, emotional, and relational. Special features include brief chapters with bullet points; an introduction, objectives, and summary in each chapter;Fast Facts in a Nutshell; tables summarizing important information: and a reference list including key resources. The book also includes a special section on chronic illness and complex health issues in teens. Each chapter contains a case study to reinforce health care interventions. This is a compact, affordable resource for students and health professionals "on the front lines" alike.

Key Features: Identifies and addresses the key aspects of working with adolescents in an accessible, portable, and user-friendly format Written by a highly respected leader of adolescent nursing Presents a broad spectrum of adolescent health issues in many settings Incorporates current issues related to adolescent health and risk behaviors throughout Includes information on communicating and intervening with teens

This book provides an overview of recent advances in the study of aging and aging related diseases, discussing the topics at individual, organ, tissue, cell, and molecular levels. It also presents studies on the biomarkers of aging and anti-aging interventions. Aging has been becoming a global health problem. However it was not possible to determine aging as we usually diagnose a disease because there are few biomarkers for age estimation. Since ancient times, people have been seeking anti-aging substances and methods for achieving immortality, while the scientific study of aging has only existed for 100 years. This book appeals to researchers both in institutes and in pharmaceutical companies interested in further studies in this field.

Wisdom Mind is a scientifically tested mindfulness program for older adults - those who are cognitively healthy, as well as those who may be experiencing what is referred to as subjective cognitive decline. While mindfulness is already known to benefit a wide variety of individuals, the unique strengths of this program are the ways in which it is tailored specifically to older adults. Session content is keyed to common concerns of older adults (such as cognitive slip-ups, loss, and grief), and incorporates strategies for building upon mindfulness practices in a sequence of increasing difficulty as well as strategies to promote learning and integration. Designed to be used alongside the companion Facilitator Guide, this session-by-session Participant Workbook provides detailed information on how to take part in the program, as well as the reasoning behind why certain practices and strategies are provided at different times and in different ways. As such, it will be of interest to those familiar with mindfulness as well as those new to the practice. A companion website provides downloadable meditation audio recordings that participants can access throughout the program.

A candid assessment of the pros and cons of delayed motherhood.
Biology does not bend to feminist ideals and science does not work miracles. That is the message of this eye-opening discussion of the consequences of delayed motherhood. Part personal account, part manifesto, Selvaratnam recounts her emotional journey through multiple miscarriages after the age of 37. Her doctor told her she still "had time," but Selvaratnam found little reliable and often conflicting information about a mature woman's biological ability (or inability) to conceive.
Beyond her personal story, the author speaks to women in similar situations around the country, as well as fertility doctors, adoption counselors, reproductive health professionals, celebrities, feminists, journalists, and sociologists. Through in-depth reporting and her own experience, Selvaratnam urges more widespread education and open discussion about delayed motherhood in the hope that long-lasting solutions can take effect. The result is a book full of valuable information that will enable women to make smarter choices about their reproductive futures and to strike a more realistic balance between science, society and personal goals.

Statistical Analysis of Human Growth and Development is an accessible and practical guide to a wide range of basic and advanced statistical methods that are useful for studying human growth and development. Designed for nonstatisticians and statisticians new to the analysis of growth and development data, the book collects methods scattered throughout the literature and explains how to use them to solve common research problems. It also discusses how well a method addresses a specific scientific question and how to interpret and present the analytic results. Stata is used to implement the analyses, with Stata codes and macros for generating example data sets, a detrended Q-Q plot, and weighted maximum likelihood estimation of binary items available on the book's CRC Press web page. After reviewing research designs and basic statistical tools, the author discusses the use of existing tools to transform raw data into analyzable variables and back-transform them to raw data. He covers regression analysis of quantitative, binary, and censored data as well as the analysis of repeated measurements and clustered data. He also describes the development of new growth references and developmental indices, the generation of key variables based on longitudinal data, and the processes to verify the validity and reliability of measurement tools. Looking at the larger picture of research practice, the book concludes with coverage of missing values, multiplicity problems, and multivariable regression. Along with two simulated data sets, numerous examples from real experimental and observational studies illustrate the concepts and methods. Although the book focuses on examples of anthropometric measurements and changes in cognitive, social-emotional, locomotor, and other abilities, the ideas are applicable to many other physical and psychosocial phenomena, such as lung function and depressive symptoms.

"A remarkable collection of scholarly essays, philosophical discussions, and ethical arguments concerning reproductive choices."
--"Choice"

It seems as if every week there is a new case involving reproductive technologies that raises provocative, often painful questions: What policies should be followed by centers that preserve human embryos? Are such innovations as Norplant improvements over established methods of contraception? Should R.U. 486 be available in the U.S.? Is prenatal diagnosis an ethically acceptable step to limiting the number of disabled people?

These are just some of the vital questions explored in this timely work which offers incisive analysis of the plethora of issues raised by advances in reproductive medicine. The book's major section cover abortion, contraception, cryopreservation of gametes and embryos, surrogate motherhood, and psychosocial issues of in-vitro fertilization.

In each section, introductory essays by recognized authorities such as Elizabeth Bartholet and Andrea L. Bonnicksen are followed by critical articles by professionals in such fields as women's health, medicine, biology, sociology, politics, and philosophy. In assessing a technology, the authors present well-argued analyses of problems created by that technology, including views from advocates and practitioners that raise attendant ethical and practical issues.

In Male Mid-Life Crisis, Justin K. Lim investigates this phase of human life through the perspectives of analytical psychology and through existential theology. Research suggests 80 percent of men suffer from this crisis, and that it is not limited to any culture or period of history. He applies his findings to pastoral/spiritual interventions, seeking deeper and broader psychological and theological insights.

This practical, extensively illustrated handbook covers the procedures that are undertaken in andrology and ART laboratories to analyse and assess male-factor infertility, and to prepare spermatozoa for use in assisted conception therapy. The content is presented as brief, authoritative overviews of the relevant biological background for each area, plus detailed, step-by-step descriptions of the relevant analytical procedures. Each technical section includes quality control considerations and the optimum presentation of results. In addition to the comprehensive 'basic' semen analysis, incorporating careful analysis of sperm morphology, the handbook provides established techniques for the use of computer-aided sperm analysis and sperm functional assessment. The interpretation of laboratory results in the clinical context is highlighted throughout, and safe laboratory practice is emphasized. Fully revised, incorporating the new ISO TS 23162 on basic human semen analysis throughout, this is an invaluable resource to all scientists and technicians who perform diagnostic testing for male-factor infertility.

The book considers signaling events from the zygote embryo through to the blastocyst with relevant data from embryonic stem (ES) cells, including dialogue with the extracellular environment and with the maternal tract during the implantation process. Application of the knowledge described to improve the success of human and animal assisted conception is considered where appropriate, but the focus is largely on fundamental rather than applied cell/molecular biology, as this is the area that has historically been neglected. While the general features of metabolism during preimplantation development are well established, especially in terms of nutrient requirements, uptake and fate, remarkably little is known about early embryo signaling events, intracellular or intercellular, between individual embryos in vitro or with the female reproductive tract in vivo. This contrasts with the wealth of information on cell signaling in somatic cells and tissues, as a glance at any textbook of biochemistry illustrates. This lack of information is such that our understanding of the molecular cell biology of early embryos -- a prerequisite to defining the mechanisms which regulate development at this critical stage of the life cycle -- is seriously incomplete. This volume is the first to address this issue by describing the current state of knowledge on cell signaling during mammalian early embryo development and highlighting priority areas for research.