The incidence of fungal infections increases with the increase in antibiotic usage and increasing immunosuppressed populations. There is no longer only one antifungal agent and the response of fungi to various agents is not always predictable. The need for standardized antifungal susceptibility testing, and standardized interpretation of results in conjunction with studies that describe clinical outcomes based on those tools is ever important. Interactions of Yeasts, Moulds, and Antifungal Agents: How to Detect Resistance covers the available antifungal agents, how to perform in vitro testing and how those results should be interpreted for the most common fungal pathogens.

Increasing resistance to established fungicides has stimulated the search for novel fungicides with new modes of action. Environmental concerns now also demand that these have low environmental impact and toxicity. Fungicidal Activity discusses new approaches to fungicide development including biological control and genetic engineering, and takes a global view of the future of fungicidal development. Fungicidal Activity is a volume in the Wiley Series in Agrochemicals and Plant Protection. This series brings together current scientific and regulatory knowledge and perspectives on all aspects of the use of chemicals and biotechnology in agriculture.

Stored product insects and other pests represent a major hygiene and safety issue to many industries, from food production to building infestation, and issues for timber pallets and packaging. Beds bugs are rapidly becoming a public health issue in hotels, hostels and houses in many parts of the world. While fumigation has been one of the prevalent routes for pest control, there remain issues with the toxicity of the chemicals used and potential exposure to humans therefore heat treatment has proven to be a successful alternative when used correctly.

It is well known that excessive heat is dangerous to life. There is a difference between the amount of heat required to kill microbes such as bacteria and viruses and that required to kill larger life forms such as insects or mammals. This book focuses on the use of heat to kill insects and mites in food production, storage and other facilities.

Heat Treatment for Insect Control examines how controlled heat treatment kills all stages of pest insect life across species and without causing damage to surrounding structures or electronics. The advantages of heat treatment include no health & safety hazards, a completely controllable and environmentally friendly process, reduced treatment time of fumigation (hours verses days), as well as no factory shutdown or exclusion of staff from adjacent areas during treatment.

Part I reviews the principles of heat treatment, with chapters covering the fundamentals, planning, best practice and costs of integrated pest management. Part II looks at heat treatment applications in food production, storage, food materials and fresh produce. Part III examines the other applications in clothing, small rooms, buildings, and transportation.
Provides a comprehensive and systematic reference on the heat treatment for insect controlReviews the development of heat treatment processes and technology as part of integrated pest management approaches

Many biological studies on insect management do not consider economics or fundamental economic principles. This book brings together economists and entomologists to explain the principles, successes, and challenges of effective insect management. It highlights the importance of economic analyses for decision making and the feasibility of such approaches, and examines integrated pest management (IPM) practices from around the world with an emphasis on agriculture and public health. The book begins by establishing an economic framework upon which to apply the principles of IPM. It continues to examine the entomological applications of economics, specifically, economic analyses concerning chemical, biological, and genetic control tactics as well as host plant resistance and the cost of sampling and is illustrated with case studies of economic-based IPM programs from around the world.

Ever been tempted by the thought of trying juicy deep fried mealworms, proteinrich cricket flower, or swapping your Walkers for salt and vinegar flavoured grasshoppers? If so then you are not alone! Over 2 billion people regularly eat insects as part of their diet, and the world is home to around 1,900 edible insect species. For adventurous foodies and daring dieters comes the newest way to save the planet, eat more protein, and tickle taste buds. But this isn't an insect cookbook. Instead it's an informative field guide: exploring the origins of insect eating, offering tips on finding edible bugs and serving up a few delicious ideas of how to eat them once you've tracked them down! It includes a comprehensive list on edible insects and where to find them, how to prepare them, their versatile usage and nutritional value as well as a few recipes. A bug-eating checklist covering all known edible bugs so readers can mark off the ones they've eaten and seek out new delicacies concludes the book. This is a perfect introduction to the weird, wonderful, and adventurous side of entomophagy.

Agricultural production is in a period of rapid transformation which has seen an increase in the use of biotechnology, synthetic chemistry, biological chemicals and biopesticides. These disciplines are integrated with improvements in application technology, digital farming and the use of big data. Whilst offering unique opportunities to reduce potential environmental impacts, these advances also raise new environmental concerns. This book provides an overview of the changes occurring in the agricultural industry, highlighting opportunities to address impacts and indicating potential barriers to adoption of the technology. This new edition has been updated to include the very latest in agricultural developments, including organic farming and genetically modified crops. It is of interest to students and academics, as well as farmers and landowners and those working in legislation.

Evaluates the carcinogenic risk to humans posed by occupational exposure during the spraying and application of insecticides. The book also features separate monographs evaluating the carcinogenicity of 17 individual pesticides, including several that have been banned by industrialized countries yet are still used in the developing world. Although some of these pesticides have been in use for more than four decades, evaluations of carcinogenicity were hindered by the sparsity of well-designed epidemiological studies. The first and most extensive monograph evaluates data from descriptive and ecological studies, cohort studies, and case-control studies suggesting an increased risk of cancer, most notably lung cancer, multiple myeloma and other tumours of B-cell origin, in workers exposed to insecticides during their application. On the basis of this evaluation, the book concludes that the spraying and application of nonarsenical insecticides entail exposures that are probably carcinogenic to humans. The remaining monographs evaluate the carcinogenicity of aldicarb, atrazine, captafol, chlordane, DDT, deltamethrin, dichlorvos, fenvalerate, heptachlor, monuron, pentachlorophenol, permethrin, picloram, simazine, thiram, trifluralin, and zitram. Of these, captafol, a fungicide used on plants, for seed treatment, and as a wood preservative, was classified as probably carcinogenic to humans. Atrazine, chlordane, DDT, dichlorvos, heptachlor, and pentachlorophenol were classified as possibly carcinogenic to humans. The remaining pesticides could not be classified on the basis of available data.

In this handbook, the authors present current research in the study of the biological activity, classification and health and environmental implications of herbicides. Topics discussed include productive degradation of dichlorprop by transconjugant strains; weeds and their mechanisms of resistance to herbicides; application of 31P-NMR spectroscopy to glyphosate studies in plants; lethal and sublethal glyphosate effects on non-target fish species; chemical properties and genotoxic effects of phenylurea herbicides; action mode of triazines and toxic effects on vertebrates; photolysis experiments on alloxydim herbicide and biological response of its transformation product; glyphosate-resistant weeds in Southern Europe; herbicide paraquat genotoxicity-enhancement by the phenolic antioxidants Dl-A-tocopherl and 2,6-Di-Tert-Butyl-P-Cresol; glyphosate adsorption in a soil depth profile; adsorption-desorption processes and mobility of (4-Chloro-2-Methylophenoxy) acetic acid (Mcpa) in Irish grassland soils; pesticides and cancer with a study on the interaction of phenoxy acid herbicides with DNA; herbicidal activity of pyrazole derivatives; behaviour of herbicides in paddy water and soil after application; and laboratory lysimeter for pesticide transport studies.

The "Handbook of Pesticide Toxicology" is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the "Handbook of Pesticide Toxicology" is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book s tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition.
Feature: Presents a comprehensive look at all aspects of pesticide toxicology in one reference work.
Benefit: Saves researchers time in quickly accessing the very latest definitive details on toxicity of specific pesticides as opposed to searching through thousands of journal articles.

Feature: Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions
Benefit: Connects the experimental laboratory results to real-life applications in human health, animal health and the environment.

Feature: All major classes of pesticide considered.
Benefit: Provides relevance to a wider variety of researchers who are conducting comparative work in pesticides or their health impacts.

Feature: Different routes of exposure critically evaluated.
Benefit: Connects the loop between exposure and harmful affects to those who are researching the affects of pesticides on humans or wildlife.
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Palladium is a steel-white, ductile metallic element resembling and occurring with the other platinum group metals and nickel. Palladium and its alloys are used in the (petro) chemical and the automotive industries as catalysts, in dentistry, and in electronics and the, electrical industry.This book evaluates the risks to human health and the environment posed by exposures to palladium. The general population is primarily exposed to palladium through dental alloys or jewellery. There were case reports referring to palladium sensitivity associated with exposure to palladium-containing dental restorations; the, symptoms being contact dermatitis, stomatitis or mucositis and oral lichen planus.Palladium ions are considered to be highly toxic to aquatic organisms. However, due to palladium's high economic value, emissions of palladium from point sources are currently minimal. Increased use of catalytic converters may increase palladium emissions from diffuse sources. It was recommended that these emissions should, be controlled to be as low as possible.

Evaluates the risks to human health and the environment posed by exposure to dinitro-"ortho"-cresol, a chemical used for over a century as an acaricide, larvicide, and ovicide to control the dormant forms of many insects in orchards. The chemical is also sprayed on potatoes to prevent virus and disease contamination of the tubers. Although the chemical's use as a pesticide has been banned in many countries, significant volumes of obsolete stocks are still found in several parts of the world, especially in developing countries. Dinitro-"ortho"-cresol continues to be used in the plastics industry as an inhibitor of polymerization in styrene and vinyl aromatic compounds. Concerning environmental behavior studies indicate that the chemical is rapidly biodegraded in soil and has no potential to volatilize when released to water. Evidence further suggests that uptake by treated fruit trees or potatoes leaving residues at harvest time does not occur. Food is therefore not considered an important source of exposure for the general population. Occupational exposures during agricultural spraying and during manufacturing and formulation are regarded as the principal sources of human exposure. The most extensive part evaluates the results of toxicity studies in laboratory mammals and "in vitro "test systems. Short-term dietary administration decreased body-weight gain in some species, usually without significant alteration in food consumption. At high doses, adverse effects on the liver have been observed. Data on embryotoxicity, teratogenicity, mutagenicity, and carcinogenicity were judged inadequate for evaluation. The evaluation of effects on human health draws on data obtained during the limited use of dinitro-"ortho"-cresol in the 1930s as a therapeutic agent for the treatment of obesity and on cases of acute poisoning. Symptoms associated with toxicity include restlessness, flushed skin, sweating, thirst, deep and rapid respiration, severe increase of body temperature, and cyanosis leading to collapse, coma, and death. Concerning adverse effects on occupationally exposed workers, the report cites a dramatic decline over the last 25 years in reported cases of occupational intoxication. The decline is attributed to better education of users, the use of adequate protective equipment, and improvements in application techniques, equipment, and formulations. The report concludes that when used according to registered recommendations, and when measures for personal protection are followed, exposure to dinitro-"ortho"-cresol is reduced to levels that do not cause systemic toxicity.

Evaluates the carcinogenic risk to humans posed by exposure to selected miscellaneous pesticides.

In the first chapter of the book, the immunotoxicological risk arising from xenogenous substances is emphasised. Immunotoxicology investigates unwanted adverse effects of xenobiotics on the immune system of man and animals. With regards to insecticides and pest control, several studies showed that the insect endocrine system, especially anti-stress neuropeptides, could be used as a potential target for pest control. The second chapter examines the enhancement of insecticide efficacy specifically by adipokinetic hormones. In the third chapter, the authors propose, based on their research, that the combined use of different methods such as the use of biological control agents of insect vectors of aflatoxigenic fungi, plus the use of food grade antioxidants in sublethal doses, could help reduce aflatoxins in stored maize. Maize is a crop of major economic importance in the world because it is used as human and/or livestock feed. This chapter reviews the integrated management of insect vectors of aflatoxigenic fungi in stored maize. The fourth and last chapter of this book summarises the relationship between soil nematode communities as bioindicators of soil health and quality and application of insecticides used for the control of Western corn rootworm (WCR) in the maize field.

The U.S. Armed Forces used a variety of chemical defoliants to clear dense jungle land in Vietnam during the war. Agent Orange (named for the orange-colored identifying stripes on the barrels) was by far the most widely used herbicide during the Vietnam War. Many Vietnam-era veterans believe that their exposure to Agent Orange caused them to contract several diseases and caused certain disabilities, including birth defects in their children, and now their grandchildren. This book provides an overview of how Congress and the judiciary have addressed the concerns of Vietnam-era veterans and briefly describes some of the current issues raised by Vietnam-era veterans. Furthermore, underground coal miners face the threat of being overexposed to coal mine dust, which can cause CWP and other lung diseases, collectively referred to as black lung disease. The book examines the extent to which the Mine Safety and Health Administration (MSHA) used recent CWP trend data as a basis for its proposed exposure limit; and expert views on ways to lower the level of dust in coal mines, including their associated advantages, disadvantages, and cost. Finally, this book discusses the Radiation Exposure Compensation Act (RECA). The RECA was enacted in 1990 and provides one-time cash benefits to certain persons who participated in atomic weapons testing or lived near the Nevada Test Site during periods of atmospheric (above-ground) atomic weapons testing. Benefits under RECA are also available to certain uranium miners, mill workers, and ore transporters who worked in the uranium industry between 1942 and 1971, when the federal government stopped its procurement of radiation for the atomic weapons program.

This publication is rare among those texts on pesticides in that it covers herbicides exclusively. It presents, in one source, information that is typically scattered. This important publication enables the reader to recommend herbicide use more reliably and efficiently. It also highlights environmental issues relevant to herbicide use in agriculture. The book outlines potential areas of further research. This title is of particular value to weed scientists, environmental chemists and engineers, soil scientists, and those responsible for recommending and/or regulating use of herbicides in agriculture. Focuses On: ? Increasing efficiency of herbicides in agriculture ? Decreasing environmental contamination with herbicides ? Dissipation and transformations in water and sediment ? Nature, transport, and fate of airborne residues ? Absorption and transport in plants ? Transformations in biosphere ? Bioaccumulation and food chain accumulation ? Photochemical transformations ? Bound residues ? Predictability and environmental chemistry

Is it really true that martial arts, in spite of their popularity in this day and age of ours, have, at their deepest level, the promised land of "self-knowledge," "the expression of beauty," or something highly spiritual to be pursued for the human soul? Or, to put it in a different way, what exactly makes martial arts so amazing that, somehow, they will eventually lead the practitioners to the spiritual realm of self-cultivation in its highest depth? Contrary to the conventional wisdom about martial arts as held by many over the ages, this popular view about martial arts has become so legendary that their dark sides have yet to be systematically explored and that the lofty aims of martial arts are neither possible nor desirable to the extent that their proponents would like us to believe.Of course, this is not to say that the very tradition of martial arts is absolutely useless, or that the literature on martial arts hitherto existing in history is spiritually unworthy to be appreciated. Instead, this book constructively offers an alternative (better) way to understand the nature of martial arts, in special relation to the body and spirit of warriors-while learning from different views in the literature, without favoring any one of them (nor integrating them, as they are not necessarily compatible with each other), and, in the end, transcending them towards a new horizon not conceived before. This seminal view, if proven valid, will fundamentally change the legendary way that people have thought about martial arts-from the combined perspectives of the mind, nature, society, and culture, with enormous implications for the human future and what I originally called its "post-human" fate._____________________