Dyslipidemia affects almost half of American adults and is the most prevalent manageable risk factor for atherosclerosis. Lipid disorders often co-occur with other prevalent conditions such as diabetes and kidney disease; they are also often a concern with certain medication regimens (such as anti-retroviral and certain anti-psychotic agents). Proper treatment of dyslipidemia can reduce the risk of peripheral arterial disease, revascularization procedures, nonfatal myocardial infarction, stroke, and cardiac death. However, only 20% of adults meet the national guidelines for cholesterol control. As part of the Oxford American Cardiology Library, this practical handbook is designed to serve as a concise yet authoritative resource on diagnosing and treating dyslipidemia. The book is tailored to the needs of busy health care professionals treating patients in various clinical settings, and focuses on presenting essential information to clinicians who are at the forefront of the diagnosis and management of dyslipidemia. Featuring evidence-based, concise yet comprehensive discussion of key clinical concepts in addition to numerous figures, tables and illustrations, this pocket-sized handbook will serve as an invaluable guide to healthcare professionals. Features: * Authored by a renowned international group of experts on dyslipidemia. * Chapters include vignettes to enhance clinical relevance.

This is an optimistic and empowering approach to the daunting task of teaching diabetes patients to care for themselves. Written by a highly respected diabetes educator who has suffered with diabetes for 25 years, the guide provides the clinical and personal expertise that will help nurses and other health professionals to successfully teach diabetes self-management and compliance to adults, children, adolescents, and parents.

The book contains a vast reservoir of information ranging from a thorough overview of diabetes and the physical and emotional toll of living with the disease to number of teaching and motivating strategies that health care professionals can use to create individualized approaches to teaching self-management skills. The guide provides up-to-date information on drug therapies, nutrition management, exercise, chronic complications, glycemic control, diabetes in children, adolescents, and adults, diabetes in adults with special needs or mental illness, and diabetes noncompliance. Addressing the most important and current topics necessary for successful self-regulation and maintenance of diabetes, this innovative desk reference provides a quick guide and instructional tool for nurses and other health professionals who interact with diabetics. This new edition provides:

Clinical guidance and expertise to successfully teach diabetes self-management to adults, adolescents, and children The clinical expertise of a leading diabetes educator and the hard-earned personal wisdom of an author who has suffered with diabetes for 25 years A new chapter on chronic complications that describes a multitude of helpful new treatments A greatly expanded section on nutrition and exercise Thoroughly updated chapters A "must read" chapter on noncompliance, including why this occurs and how to prevent it

Metabolomics is the logical progression of the study of genes, transcripts and proteins. Nutrients, gut microbial metabolites and other bioactive food constituents interact with the body at system, organ, cellular and molecular levels, and effect the expression of genome at several levels, and subsequently, the production of metabolites. This book presents an overview of nutrigenomics and metabolomics tools, and their perspective in livestock health and production. In addition, this book describes how lists of masses (molecular ions) and mass unit bins of interest are searched within online databases for compound identification, the extra biochemical data required for metabolite confirmation, how data are visualised and what the putative and protein sequences are associated with observed metabolic changes. Moreover, environmental metabolomics is the application of metabolomics to the investigation of both free-living organisms directly obtained from the natural environment or laboratory conditions. This book outlines some of the advances made in areas of plant environmental metabolomics. The applications of microbial metagenomics, the use of genomics techniques to the study of communities of directly in their diverse natural environments, are explored as well. Other chapters examine the abnormalities in metabolism of cancer cells, which could play a strategic role in tumour initiation and behaviour.

Metabolism represents a complex system characterised by a high variability in metabolites' structure, concentration and regulation ratio. Such variability is observed at different metabolic scales going from metabolites to metabolic profiles via chemical reactions and metabolic pathways, as well as under static or dynamic aspects. Variations in these components are due to apparition-disappearance, level increase-decrease and/or relative changes in weights or contributions leading to different structural, functional and evolutive states of the metabolic system. This book presents a variety of different computational approaches of the variability in metabolic systems.

Carbohydrates play an important role in many biological and biochemical processes, including the fertilisation, cell differentiation and maturation, protein folding and degradation. Carbohydrates are also involved in a variety of recognition events, such as cell-cell and cell-matrix interactions. Many of these are immunologically relevant processes, namely inflammation host-pathogen interactions, immune response and health disorders, such as arthritis, Alzheimer's disease, among others. Carbohydrate-active enzymes(CAZymes) play key roles in glycobiology. They are involved in the synthesis and degradation of complex carbohydrates and glyco-conjugates.

This book provides a wealth of data on clinical research, molecular biology and biochemistry of magnesium. The book also aims to correct a number of misconceptions concerning biological roles of magnesium. Synergic interactions of magnesium with pyridoxine as well as with minerals and with drugs are detailed. The book can be recommended to doctors of different specialities (neurologists, cardiologists, physicians, paediatricians, obstetricians and gynaecologists, pathologists, nutritionists and others) which can fruitfully use the information presented in the book in their clinical practice. The book will also be helpful to medical students studying experimental and clinical pharmacology.

For the most honest, objective opinion, HealthScouter provides a patient's view of the most common medical problems. Including hundreds of quotes, questions, and answers from patients themselves, this guide provides comprehensive information about a single condition for from perspective that matters: the patient's perspective. Understand how current patients approach their medical challenges, and help overcome your own. This reference will help you see through obscure medical jargon and limited treatment options and empower you to better understand the issues that really matter: Diagnosis + Symptoms + What to Expect + Treatment Options + Medical Terminology

Why Do I Still Have Thyroid Symptoms? was written to address the true causes of hypothyroidism in this country and how to manage them. The vast majority of hypothyroid cases are caused by Hashimoto's disease, an autoimmune reaction, and are being treated inappropriately or misdiagnosed by the standard health care model. Through exhaustive research and clinical experience, Dr. Kharrazian has discovered the many causes of hypothyroidism, including autoimmunity, and how to manage it. NOTE: This is the same thyroid book but under a new publisher. To read reviews of the book, please visit the old listing at http: //www.amazon.com/Still-Thyroid-Symptoms-Tests-Normal/dp/1600376703/ref=sr_1_1?ie=UTF8&qid=1348258676&sr=8-1&keywords=kharrazian.

A new work on the history of vitamins and the brilliant men and women who discovered the existence and nature of these small molecules so vital to our health. Vitamin Discoveries and Disasters: History, Science, and Controversies describes the emergence of nutritional science and its contributions to our understanding of how the body functions. It is an absorbing look at the men and women, many little known in their lifetimes, whose medical detective work helped us conquer a number of devastating health conditions, including some forms of mental illness. Each chapter of Vitamin Discoveries and Disasters focuses on a specific vitamin, describing the researchers, the research, and the historic and scientific contexts for its discovery. Together, these chapters chart the ongoing conflict between physicians who saw illness as caused by organisms and those who saw illness as a result of dietary deficiency. A concluding chapter shows how our stronger grasp of the effects of vitamin deficiencies on large populations can be used to the utmost benefit of society.

1.1 Historischer UEberblick.- 1.2 Wirkungsmechanismus.- Indikationen.- 2.1 Benigne Erkrankungen.- 2.1.1 Struma mit Euthyreose.- 2.1.2 Funktionelle Autonomie.- 2.1.3 Immunogene Hyperthyreose.- 2.2 Maligne Erkrankungen.- Praktische Durchfuhrung.- 3.1 Strahlenschutzvoraussetzungen/ neue gesetzliche Bestimmungen.- 3.2 Dosiskalkulation - Radiojodtest.- 3.3 Durchfuhrung der Therapie.- 3.4 Bauliche Voraussetzungen.- Ergebnisse.- 4.1 Benigne Erkrankungen.- 4.1.1 Euthyreote Struma.- 4.1.2 Funktionelle Autonomie.- 4.1.3 Immunogene Hyperthyreose.- 4.2 Maligne Erkrankungen.- Nebenwirkungen.- 5.1 Benigne Erkrankungen.- 5.2 Maligne Erkrankungen.- Nachsorge und medikamentoese Nachbehandlung.- 6.1 Benigne Erkrankungen.- 6.2 Maligne Erkrankungen.- Literatur.- Anhang A Verzeichnis der deutschen Therapiezentren.- Anhang B Leitlinien zur Radiojodtherapie.- Leitlinien der Deutschen Gesellschaft fur Nuklearmedizin Leitlinie zur Radiojodtherapie (RIT) beim differenzierten Schilddrusenkarzinom (Stand des Entwurfs 25.1.99).- Leitlinien der Deutschen Gesellschaft fur Nuklearmedizin Leitlinie zur Radiojodtherapie (RIT) bei benignen Schilddrusenerkrankungen (Stand des Entwurfs 25.1.99).- Sachferzeichnis.

This book discusses, in relatively simple language, the importance of even minute amounts of certain trace elements for the protection of human health and how insufficiency or excess may produce serious diseases. It also examines the use of metal chelators in the treatment of such diseases. Trace Element Medicine and Chelation Therapy looks at the role of metal ions in the evolution and development of living systems and reviews the elemental composition of the human body, the essential biochemistry of metal ions, metal complexes, and the concepts of chemical speciation, as well as the interactions of metals with chelating agents, ligands and drugs. The problems of delivering adequate amounts of trace elements to the human body and the roles of metal containing drugs are also discussed, while the role of chelating agents in the treatment of both spontaneous and accidental overload and the dietary and environmental aspects of such treatment are both comprehensively reviewed. Trace Element Medicine and Chelation Therapy will assist chemists in understanding more about these metal ions and the influences of industrialization and pollution, and will illuminate physicians involved in administering chelation therapy. It illustrates the interdisciplinary nature of the subject and will be of immense interest to students and researchers in chemistry, biochemistry, nutrition and food science, environmental sciences, pharmacology and medicine, as well as to school science teachers and scientifically oriented members of the public.

This comprehensive volume completes Frederic Holmes's notable and detailed biography of Hans Krebs, from the investigator's early development through the major phase of his groundbreaking investigation, which lay the foundations upon which the modern structure of intermediary metabolism is built. With access to Krebs's research notebooks as well as to Krebs himself through more than five years of personal interviews, the author provides an insightful analysis of Hans Krebs and of the scientific process as a whole. The first volume, published in 1991, covered Krebs's formative years in Germany, his work with Otto Warburg, and his discovery of the urea cycle in 1932. This second volume reconstructs the investigative pathway and the professional and personal life of Hans Krebs, from the time of his arrival in England in 1933 until 1937, when he made the discovery for which he is best known-the formulation of the citric acid cycle. Holmes portrays Krebs's activity at the intimate level of daily interactions of thought and action, from which the characteristic patterns of scientific creativity can best be seen. Holmes's fascinating portrait of Krebs integrates the great scientist's investigative pathways with his personal life. The result is an illuminating analysis of both man and scientist that will be of interest to biochemists and historians of science.

This text presents a compilation of topics that have been taught at Metabolic University (MU), an interactive, didactic educational program that has trained over 600 metabolic dietitians/nutritionists, physicians, nurses and genetic counselors. This book was created in 2014 for the metabolic community. The 1st edition contains only subject matter covered at Metabolic University; therefore, it is not a comprehensive treatise on Inherited Metabolic Disorders (IMD) but rather a text on the most frequently encountered challenges in IMD nutrition. Each chapter in the book highlights principles of nutrition management, how to initiate a diet, and biomarkers to monitor the diet. Recognizing that there are variations in practice, this book addresses that the key to management lies in the understanding how the inactivity of an enzyme in a metabolic pathway determines which components of the diet must be restricted and which must be supplemented as well as the monitoring of appropriate biomarkers to make diet adjustments and ensure the goals of therapy are met The 2nd edition is an updated and more extensive version covering the nutrition management of IMD, and covers a wide range of these disorders, including phenylketonuria and other aminoacidopathies, organic acidemias, urea cycle disorders, fatty acid oxidation disorders, galactosemia and glycogen storage diseases. Guidance is also provided on laboratory evaluations and biochemical testing and monitoring. Topics such as newborn screening for IMD, as well as nutrition management during pregnancy and transplantation, are also addressed. In addition, current medical management therapies is included.

This book provides an up-to-date review of the fundamentals of sphingolipid metabolism and its role in metabolic diseases. Focusing on the sphingolipid de novo synthesis pathway, the effect of sphingomyelin, ceramide, and sphingosine-1-phosphate, and linkage between sphingolipids and other lipids, such as cholesterol, it covers serine palmitoyltransferase, ceramide synthases, ceramidases, sphingosine kinases, and sphingomyelin synthases, and more. While highlighting how rare diseases related to abnormal glycosphingolipid metabolism, this publication introduces sphingolipid metabolism-related diseases, such as lung diseases and cancers, as well as sphingolipid circadian regulation. The book demonstrates advances and limitations of research on sphingolipid metabolism and its roles in metabolic diseases and other diseases. It offers graduate students and researchers a coherent overview of sphingolipids, as well as the limitations of current research in the field, and promotes further studies on metabolic diseases, as well as pharmaceutical research on drug discovery based on sphingolipid de novo synthase.

Jeder 5. Patient in der Arztpraxis hat Diabetes

Grundlagen, Diagnostik, Therapie:
Knapp, praxisorientiert, fur die taglichen ProblemeTherapierichtlinien:
Konkrete Therapieziele, neueste Therapeutika und deren BewertungInformation zu jeder relevanten Situation:
Diabetiker auf Reisen, Behandlung diabetischer Entgleisungen Hilfreiche Leitfaden:
Notfalle, perioperative/periinterventionelle Versorgung Zusatznutzen:
Abkurzungsverzeichnis, wichtige Internetadressen und Organisationen

NEU u.a.Neueste TherapiekonzepteNeueste Richtwerte, Studien und Leitlinien berucksichtigt

Zusatzinhalte im Internet: Vorlagen/Checklisten fur das Diabetes-TeamInformationsunterlagen fur PatientenAnleitungen zur Optimierung der Arbeitsablaufe

Fur Allgemeinmediziner, Internisten, Gynakologen, Padiater, Diabetologen, Diabetesberaterinnen und Ernahrungsberaterinnen.

Mit den wichtigsten Tipps, Tricks und Infos aus der taglichen Praxis von multiprofessionellen Diabetes-Teams.

Das beliebte und erfolgreiche Diabetes-Handbuch fur Arztpraxis und Klinik noch besser "

This book summarizes the effects of obesity on health and its correlation with a wide range of debilitating and life-threatening conditions in humans. It discusses the possible pathological mechanisms that are involved in the development of obesity and highlights obesity-associated molecular mechanisms that contribute to reproductive dysfunctions in men and women. The book provides mechanistic insights on the role of obesity in cardiovascular and respiratory disorders, and examines the role of the complementary molecular mechanism of the gut microbiota in the development of obesity. It also reviews the interaction between the metabolic system and immune cells in the pathogenesis of obesity-associated diseases. Lastly, it assesses the latest advances in nanomedicine as an emerging strategy for the treatment of obesity.