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Books > Science & Mathematics > Biology, life sciences > Microbiology (non-medical)

Topics in Ecological and Environmental Microbiology (Hardcover, Abridged edition): Thomas M. Schmidt, Moselio Schaechter Topics in Ecological and Environmental Microbiology (Hardcover, Abridged edition)
Thomas M. Schmidt, Moselio Schaechter
R2,346 Discovery Miles 23 460 Ships in 10 - 15 working days

Topics in Ecological and Environmental Microbiology provides an overview of ecological aspects of the metabolism and behavior of microbes, microbial habitats, biogeochemical cycles, and biotechnology. This essential reference was designed by selecting relevant chapters from the authoritative and comprehensive Encyclopedia of Microbiology," " 3rd edn., and inviting the original authors to update their material to include key developments and advances in the field. This concise and affordable book is an essential reference for students and researchers in microbiology, mycology, immunology, environmental sciences, and biotechnology.
Written by recognized authorities in the fieldIncludes topics such as air quality, marine habitats, food webs, and microbial adhesionProvides a thematic mix of both classic and cutting -edge reviews, with suggested further reading in each chapter

Caenorhabditis Elegans, Volume 106 - Molecular Genetics and Development (Hardcover, 2nd edition): Joel Rothman, Andrew Singson Caenorhabditis Elegans, Volume 106 - Molecular Genetics and Development (Hardcover, 2nd edition)
Joel Rothman, Andrew Singson
R4,143 Discovery Miles 41 430 Ships in 10 - 15 working days

An updated edition of the classic "Methods in Cell Biology" volume 48, this book emphasizes diverse methods and technologies needed to investigate "C. elegans," both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. By directing its audience to tried-and-true and cutting-edge recipes for research, this comprehensive collection is intended to guide investigators of "C. elegans" for years to come.

*Diverse, up-to-date techniques covered will be useful to the broadening community of "C. elegans" researchers for years to come * Chapters written by leaders in the field * Tried and true methods deliver busy researchers a one-stop compendium of essential protocols

Ecosystem Ecology and Geochemistry of Cuatro Cienegas - How to Survive in an Extremely Oligotrophic Site (Hardcover, 1st ed.... Ecosystem Ecology and Geochemistry of Cuatro Cienegas - How to Survive in an Extremely Oligotrophic Site (Hardcover, 1st ed. 2018)
Felipe Garcia-Oliva, James Elser, Valeria Souza
R3,547 R3,061 Discovery Miles 30 610 Save R486 (14%) Ships in 10 - 15 working days

Carbon (C), Nitrogen (N) and Phosphorus (P) are three of the most important elements used to build living beings, and their uptake from the environment is consequently essential for all organisms. Photosynthesis is the process in which plants absorb atmospheric C as they grow and convert it to biomass. However, plants acquire N and P only when these are available in the soil solution, which makes these elements the most limiting nutrients in plant growth and productivity in most ecosystems. When plant residues and roots decompose, the C, N and P they contain is transformed primarily into soil organic matter (SOM) or C and N can release to the atmosphere. Recent interest on the global C, N and P cycles has focused attention on the different proportion of terrestrial C, N and P stored in different ecosystem pools. Cuatro Cienegas represents an exceptional place, since the plants are not the base of the food web, they are the microbial community, that recycle the elements essential for life. In this book we describe how this is an analog of early Earth.

Advances in Virus Research, Volume 81 (Hardcover): Karl Maramorosch, Frederick A. Murphy Advances in Virus Research, Volume 81 (Hardcover)
Karl Maramorosch, Frederick A. Murphy
R3,580 Discovery Miles 35 800 Ships in 10 - 15 working days

Published since 1953, "Advances in Virus Research" covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology. The impact factor for 2009 is 5.522, placing it 2nd in the highly competitive category of virology.

* Contributions from leading authorities * Informs and updates on all the latest developments in the field

Taxonomy of Prokaryotes, Volume 38 (Hardcover, New): Fred Rainey, Aharon Oren Taxonomy of Prokaryotes, Volume 38 (Hardcover, New)
Fred Rainey, Aharon Oren
R4,831 Discovery Miles 48 310 Ships in 10 - 15 working days

"Taxonomy of Prokaryotes," edited by two leading experts in the field, presents the most appropriate up-to-date experimental approaches in the detail required for modern microbiological research. Focusing on the methods most useful for the microbiologist interested in this specialty, this volume will be essential reading for all researchers working in microbiology, immunology, virology, mycology and parasitology. Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Established for over 30 years, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research.

Progress in Parasitology (Hardcover, 2011 ed.): Heinz Mehlhorn Progress in Parasitology (Hardcover, 2011 ed.)
Heinz Mehlhorn
R6,682 Discovery Miles 66 820 Ships in 10 - 15 working days

Parasites threaten the health of animals and humans alike. Especially in times of increasing globalization and global warming, parasites can enlarge their "kingdom" by spreading. At the same time many of the existing medical products have become ineffective. As these products have been used for many decades, parasites have developed resistances, so that they have progressed in their fight for survival. Therefore it is obvious that humans must develop new methods to face these dangers. Thus parasitological knowledge increases daily and must be formulated to be accessible for as many parasitologists (veterinarians, physicians, biologists) as possible. Therefore it is necessary that reviews reflecting the present status of the progress in many fields of research be published. Therefore this book, published on the occasion of the 50th anniversary of the German Society of Parasitology, compiles 18 reviews on recent "hot topics," including a new vaccine against malarial parasites; severe diseases with poor chances of treatment (cryptosporidiosis, coccidiosis, theileriosis); vectors (mosquitoes, ticks) and their transmission activities; and fish parasites, including molecular insights into the sex of parasites with a focus on the survival abilities that made them so dangerous. These chapters provide detailed information for researchers, as well as for teachers and students in parasitology.

Parasitoid Viruses - Symbionts and Pathogens (Hardcover): Nancy E. Beckage, Jean-Michel Drezen Parasitoid Viruses - Symbionts and Pathogens (Hardcover)
Nancy E. Beckage, Jean-Michel Drezen
R2,695 R2,535 Discovery Miles 25 350 Save R160 (6%) Ships in 10 - 15 working days

Parasitoids are parasitic insects that kill their insect hosts in immature pre-reproductive stages. Parasitoids are employed in biological control programs worldwide to kill insect pests and are environmentally safe and benign alternatives to chemical pesticides. As resistance to chemical pesticides continues to escalate in many pest populations, attention is now refocusing on biologically-based strategies to control pest species in agriculture and forestry as well as insect vector populations that transmit human and animal diseases. Parasitoids are an economically critical element in this equation and integrated pest management.

Viruses have evolved intimate associations with parasitoids, and this book features sections on both symbiotic viruses that are integrated into the wasp s chromosomal DNA (polydnaviruses) that play critical roles in suppressing host immunity during parasitism. A separate section with additional chapters on viral pathogens that infect parasitoids to cause disease and act as detrimental agents that limit effectiveness of wasp species employed in biological control of pests is also featured. A third component is a section on parasitoid venoms, which are of interest to the pharmaceutical and medical communities as well as insect-oriented biologists.
Sections focus on both virus evolution and genomics as well as proteomics and functional roles of polydnavirus-encoded gene productsInternational researchers and emerging leaders in their fields provide readers with syntheses of the latest researchIncludes content on both symbiotic viruses and pathogenic viruses, plus new research on parasitoid venomsCutting-edge section on future directions in the field covers the impacts of polydnavirus research on medicine, human health, bioengineering and the economy, increasing the value for researchers and practitioners who need to stay on top of the research in this swiftly moving field"

Pili and Flagella - Current Research and Future Trends (Hardcover): Ken Jarrell Pili and Flagella - Current Research and Future Trends (Hardcover)
Ken Jarrell
R6,654 Discovery Miles 66 540 Ships in 10 - 15 working days

Flagella-dependent motility is widespread throughout prokaryotes and is advantageous when nutrients are limited as a mechanism to migrate to more favorable environments and to compete with other micro-organisms. Flagella systems can also play an important role in additional processes, such as adhesion to substrates, biofilm formation, and host invasion in pathogenic bacteria. A variety of different classes of pili are found in prokaryotes and these structures also possess a diverse array of functions. Pili are essential for host colonization, virulence, and pathogenesis for many bacteria and, in the case of type IV pili, can also be employed for motility across solid surfaces. This book brings together some of the top scientists in the field and describes the current knowledge and latest research on prokaryotic pili and flagella. The emphasis is on the molecular biology, genetics, structure, assembly, and function of these structures. Topics include: biogenesis, structure, and function of various pili in Gram-negative and Gram-positive organisms * flagellar gene expression, structure, and assembly * the flagella motor * posttranslational modifications of flagella systems * lateral flagella systems * the origin and evolution of flagella * applications of flagella as a surface display and expression system * the flagella and pili of Archaea.

Modernization of Traditional Food Processes and Products (Hardcover, 1st ed. 2016): Anna Mcelhatton, Mustapha Missbah El Idrissi Modernization of Traditional Food Processes and Products (Hardcover, 1st ed. 2016)
Anna Mcelhatton, Mustapha Missbah El Idrissi
R3,374 Discovery Miles 33 740 Ships in 10 - 15 working days

This volume of the Trilogy of Traditional Foods, part of the ISEKI Food Series, describes important aspects of the production of foods and beverages from all over the globe. The intention of this volume is to provide readers with an appreciation of how products were initially made, and which factors have shaped their development over time. Some modern products have remained local, while others are commodities that appear in peoples' cabinets all over the world. Modernization of Traditional Food Processes and Products is divided into two sections. The first section focuses on products originating in Europe, while the second section is a collection of products from the rest of the world. Each chapter describes the origin of a particular food or beverage and discusses the changes and the science that led to the modern products found on supermarket shelves. The international List of Contributors, which includes authors from China, Thailand, India, Argentina, New Zealand, and the United Kingdom, attests to the international collaboration for which the ISEKI Food Series is known. The volume is intended for both the practicing food professional and the interested reader.

Advances in Virus Research, Volume 80 (Hardcover, New): Karl Maramorosch, Aaron J Shatkin, Frederick A. Murphy Advances in Virus Research, Volume 80 (Hardcover, New)
Karl Maramorosch, Aaron J Shatkin, Frederick A. Murphy
R4,041 Discovery Miles 40 410 Ships in 10 - 15 working days

Published since 1953, "Advances in Virus Research" covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology. The impact factor for 2009 is 5.522placing it2nd in the highly competitive category of virology.

* Contributions from leading authorities * Informs and updates on all the latest developments in the field "

Bioinformatics and Data Analysis in Microbiology (Hardcover): Ozlem Tastan Bioinformatics and Data Analysis in Microbiology (Hardcover)
Ozlem Tastan
R6,667 Discovery Miles 66 670 Ships in 10 - 15 working days

The rapid advancement of sequencing techniques, coupled with the new methodologies of bioinformatics to handle large-scale data analysis, are providing exciting opportunities for us to understand microbial communities from a variety of environments beyond previous imagination. This book provides up-to-date and detailed information on various aspects of bioinformatics data analysis with applications to microbiology.

Yarrowia lipolytica - Biotechnological Applications (Hardcover, 2013 ed.): Gerold Barth Yarrowia lipolytica - Biotechnological Applications (Hardcover, 2013 ed.)
Gerold Barth
R4,732 Discovery Miles 47 320 Ships in 10 - 15 working days

Due to various special physiological features and a genome that greatly differs in structure, gene content and organization from other yeasts, Y. lipolytica is widely used as a host system. With its characteristics, such as the ability to grow on lipids or grease, to accumulate oil and the high capacity for secretion of proteases and lipases, the yeast is of great interest for biotechnological applications. The main topics covered in this Microbiology Monograph are: expression and secretion of heterologous proteins; acid and alkaline extracellular proteases; genetics, production, biochemical characterization and biotechnological application of lipases; production and secretion of several organic acids and flagrances; as well as the functional expression of P450 systems and its use in steroid biotransformation.

Maternal Effects as Adaptations (Hardcover, New): Timothy A. Mousseau, Charles W. Fox Maternal Effects as Adaptations (Hardcover, New)
Timothy A. Mousseau, Charles W. Fox
R3,585 Discovery Miles 35 850 Ships in 10 - 15 working days

Phenotypic variation is influenced by both genetic and environmental variation. One important source of environmental variation is the maternal effect: influences of the maternal environment on offspring phenotype. Heritable maternal effects have been shown to influence the life histories, behaviour, and population dynamics of a wide variety of plants and animals. They are likely to have evolved as a mechanism for cueing offspring to appropriate development for predicted environmental conditions. This will be the first book dealing with the broad range of maternal effects.

Recent Advances in Cytometry, Part A, Volume 102 - Instrumentation, Methods (Hardcover, 5th edition): Zbigniew Darzynkiewicz,... Recent Advances in Cytometry, Part A, Volume 102 - Instrumentation, Methods (Hardcover, 5th edition)
Zbigniew Darzynkiewicz, Elena Holden, Alberto Orfao, William Telford, Donald Wlodkowic
R4,122 Discovery Miles 41 220 Ships in 10 - 15 working days

Cytometry is one of the most rapidly growing methodologies available for basic cell and molecular biology, cytogenetics, immunology, oncology, environmental sciences and also various fields of clinical medicine. Thisnew edition, split into 2 Parts, is an almost completely new book, with nearly all of the chapters devoted to new topics. Like the previous volumes on cytometry published as part of the Methods in Cell Biology series, it provides a comprehensive description of particular cytometric methods and reviews their applications. Chapters present the theoretical foundations of the described methods, their applicability in experimental laboratory and clinical settings, and describes common traps and pitfalls such as problems with data interpretation, comparison with alternative assays, and choosing the optimal assay.
* Comprehensive presentation of cytometric methods covering theoretical applications, applicability, potential pitfalls, and comparisions to alternative assays
* Discusses many new assays developed since the previous edition
* Presents recent developments in cytometric intrumentation/technology"

Red Algae in the Genomic Age (Hardcover, 2010 Ed.): Joseph Seckbach, David J. Chapman Red Algae in the Genomic Age (Hardcover, 2010 Ed.)
Joseph Seckbach, David J. Chapman
R7,643 R6,053 Discovery Miles 60 530 Save R1,590 (21%) Ships in 10 - 15 working days

r ed Algae in Genome Age book most people reading this book have childhood memories about being enthralled at the beach with those rare and mysterious living forms we knew as seaweeds. We were fascinated at that time by their range of red hues and textures, and most of all, their exotic beauty. t o a scientist, red algae represent much more than apparent features. t heir complex forms have attracted morphologists for centuries; their intricate life cycles have brought more than one surprise to plant biologists familiar only with ferns and fowering plants; their unusual tastes have been appreciated for mill- nia, and their valuable chemical constituents have been exploited for nearly as long, most recently by biotech companies; their diversity in marine, freshwater, and t- restrial environments has offered centuries of engaging entertainment for botanists eager to arrange them in orderly classifcation systems; still, the red algae continue to teach us how many more challenges need to be overcome in order to understand their biodiversity, biological functions, and evolutionary histories.

Sepsis - Diagnostic Methods and Protocols (Hardcover, 2015 ed.): Nicasio Mancini Sepsis - Diagnostic Methods and Protocols (Hardcover, 2015 ed.)
Nicasio Mancini
R4,870 Discovery Miles 48 700 Ships in 10 - 15 working days

This volume covers microbiological, clinical and patophysiological aspects of sepsis and also provides general overview chapters with every chapter discussing the real clinical impact of the discussed diagnostic approaches. Sepsis is a major clinical problem that takes an inordinate toll on human lives and economical resources. It is widely recognized that inappropriate treatment is associated with a dramatic increase in mortality, especially within the first hours, therefore clinical and microbiological diagnosis are of pivotal importance in the management of septic patients. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Sepsis: Diagnostic Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further our knowledge of this life-threatening illness.

Progress and Technological Challenges in Microbial Biotechnology (Hardcover): Igor Melnikov Progress and Technological Challenges in Microbial Biotechnology (Hardcover)
Igor Melnikov
R3,005 Discovery Miles 30 050 Ships in 10 - 15 working days
Fungal Biofilms 2020 (Hardcover): Celia F Rodrigues, Jesus A Romo Fungal Biofilms 2020 (Hardcover)
Celia F Rodrigues, Jesus A Romo
R1,355 Discovery Miles 13 550 Ships in 10 - 15 working days
Microbial-Based Biopesticides - Methods and Protocols (Hardcover, 1st Ed. 2016): Travis R. Glare, Maria E. Moran-Diez Microbial-Based Biopesticides - Methods and Protocols (Hardcover, 1st Ed. 2016)
Travis R. Glare, Maria E. Moran-Diez
R5,055 Discovery Miles 50 550 Ships in 10 - 15 working days

This volume focuses on the developmental areas of biopesticides: production, formulation, application and field efficacy. Chapters guide readers through methods and techniques on environmental, mammalian, safety, and registration. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Microbial-Based Biopesticides aims to ensure successful results in the further study of this vital field.

Geminiviruses - Impact, Challenges and Approaches (Hardcover, 1st ed. 2019): R. Vinoth Kumar Geminiviruses - Impact, Challenges and Approaches (Hardcover, 1st ed. 2019)
R. Vinoth Kumar
R3,283 R3,068 Discovery Miles 30 680 Save R215 (7%) Ships in 10 - 15 working days

This book provides in-depth information on all key aspects of geminivirus biology, e.g. the genetics and evolution, global diversity and spread of these plant pathogens, as well as the molecular mechanisms underlying their virulence. Geminiviridae is one of the largest viral families, comprising numerous plant-infecting viruses that cause diseases in crops and weeds. These diseases have been reported from nearly all continents, in particular Asia, Europe, Africa and America. The book summarizes the current state of knowledge on the interactions between plant host and virus. In addition, it discusses advances regarding the trans-replication of satellite molecules and its effect on geminiviral pathogenesis, as well as pest management strategies to combat these diseases in the field. Given its scope, the book is a must-read reference guide for all researchers and advanced students working in virology, agriculture and plant biotechnology..

Applications of Mass Spectrometry in Microbiology - From Strain Characterization to Rapid Screening for Antibiotic Resistance... Applications of Mass Spectrometry in Microbiology - From Strain Characterization to Rapid Screening for Antibiotic Resistance (Hardcover, 1st ed. 2016)
Plamen Demirev, Todd R. Sandrin
R3,980 R3,494 Discovery Miles 34 940 Save R486 (12%) Ships in 10 - 15 working days

In the last quarter century, advances in mass spectrometry (MS) have been at the forefront of efforts to map complex biological systems including the human metabolome, proteome, and microbiome. All of these developments have allowed MS to become a well-established molecular level technology for microorganism characterization. MS has demonstrated its considerable advantage as a rapid, accurate, and cost-effective method for microorganism identification, compared to conventional phenotypic techniques. In the last several years, applications of MS for microorganism characterization in research, clinical microbiology, counter-bioterrorism, food safety, and environmental monitoring have been documented in thousands of publications. Regulatory bodies in Europe, the US, and elsewhere have approved MS-based assays for infectious disease diagnostics. As of mid-2015, more than 3300 commercial MS systems for microorganism identification have been deployed worldwide in hospitals and clinical labs. While previous work has covered broader approaches in using MS to characterize microorganisms at the species level or above, this book focuses on strain-level and subtyping applications. In twelve individual chapters, innovators, leaders and practitioners in the field from around the world have contributed to a comprehensive overview of current and next-generation approaches for MS-based microbial characterization at the subspecies and strain levels. Chapters include up-to-date reference lists as well as web-links to databases, recommended software, and other useful tools. The emergence of new, antibiotic-resistant strains of human or animal pathogens is of extraordinary concern not only to the scientific and medical communities, but to the general public as well. Developments of novel MS-based assays for rapid identification of strains of antibiotic-resistant microorganisms are reviewed in the book as well. Microbiologists, bioanalytical scientists, infectious disease specialists, clinical laboratory and public health practitioners as well as researchers in universities, hospitals, government labs, and the pharmaceutical and biotechnology industries will find this book to be a timely and valuable resource.

D-Xylitol - Fermentative Production, Application and Commercialization (Hardcover, 2012 ed.): Silvio Silverio Da Silva, Anuj... D-Xylitol - Fermentative Production, Application and Commercialization (Hardcover, 2012 ed.)
Silvio Silverio Da Silva, Anuj Kumar Chandel
R5,104 R4,391 Discovery Miles 43 910 Save R713 (14%) Ships in 10 - 15 working days

Commercially, D-xylitol is produced by chemical reactions that are tailored to the requirements of various sectors. However, due to the rising interest in sustainable development and ecologically benign practices, microbial transformation processes are generally preferred over the conventional chemical conversion process. The former have multiple advantages, including less chemical load on the environment, higher efficiency, and the ability to dilute multiple downstream transformation attempts while maintaining product yield and recovery.

This book aims to disseminate the most current advances in the biotechnological production of D-xylitol and its applications in medical and health care. It is a unique collection of 15 book chapters split into 5 sections and written by experts in their respective fields, who present critical insights into several topics, review current research, and discuss future progress in this area. This book also provides essential information on hemicellulose hydrolysis to recover D-xylose, detoxification of hemicellulose hydrolysates, and improved fermentation methods for increased D-xylitol production. The highlights of strain improvement to increase the D-xylitol titers and downstream recovery of D-xylitol are also discussed in several sections. The current applications of D-xylitol in medical and health care have been used to justify the cost incurred for setting up the demonstration plant for D-xylitol production in the market. Apart from researchers and post-graduate students in the field of microbial biotechnology, this book will assist those in the business community who deal with the economic analysis of bio-based products and their marketing.

The Mechanistic Benefits of Microbial Symbionts (Hardcover, 1st ed. 2016): Christon J. Hurst The Mechanistic Benefits of Microbial Symbionts (Hardcover, 1st ed. 2016)
Christon J. Hurst
R4,788 Discovery Miles 47 880 Ships in 10 - 15 working days

This volume summarizes recent advances in our understanding of the mechanisms that produce successful symbiotic partnerships involving microorganisms. It begins with a basic introduction to the nature of and mechanistic benefits derived from symbiotic associations. Taking that background knowledge as the starting point, the next sections include chapters that examine representative examples of coevolutionary associations that have developed between species of microbes, as well as associations between microbes and plants. The authors conclude with a section covering a broad range of associations between microbes and invertebrate animals, in which they discuss the spectrum of hosts, with examples ranging from bryozoans and corals to nematodes, arthropods, and cephalopods. Join the authors on this journey of understanding!

New Weapons to Control Bacterial Growth (Hardcover, 1st ed. 2016): Tomas G. Villa, Miguel Vinas New Weapons to Control Bacterial Growth (Hardcover, 1st ed. 2016)
Tomas G. Villa, Miguel Vinas
R6,680 Discovery Miles 66 800 Ships in 10 - 15 working days

Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. It also reviews the "state of the art" of alternative treatment approaches and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics (bacteriophages or purified lysins), the specific control of pathogenic clostridia, the design of new drugs affecting DNA synthesis in bacteria, the use of fecal-matter transplant strategies, the specific control of quorum sensing responses in bacteria, the use of new peptides as antibiotics and new ways to control bacteria that cause cancer, such as Helicobacter pylori cancers.

Modeling Methods for Medical Systems Biology - Regulatory Dynamics Underlying the Emergence of Disease Processes (Hardcover,... Modeling Methods for Medical Systems Biology - Regulatory Dynamics Underlying the Emergence of Disease Processes (Hardcover, 1st ed. 2018)
Maria Elena Alvarez-Buylla Roces, Juan Carlos Martinez-Garcia, Jose Davila-Velderrain, Elisa Dominguez-Huttinger, Mariana Esther Martinez-Sanchez
R4,054 Discovery Miles 40 540 Ships in 10 - 15 working days

This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes underlying the emergence and progression of complex diseases, such as cancer. Focusing on key and early cellular bio-molecular events giving rise to the emergence of degenerative chronic disease, it builds on previous experience on the development of multi-cellular organisms, to propose a mathematical and computer based framework that allows the reader to analyze the complex interplay between bio-molecular processes and the (micro)-environment from an integrative, mechanistic, quantitative and dynamical perspective. Taking the wealth of empirical evidence that exists it will show how to build and analyze models of core regulatory networks involved in the emergence and progression of chronic degenerative diseases, using a bottom-up approach.

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