This book presents recent advances in the use of ionic liquids in medicine and pharmaceutics with particular emphasis on addressing critical pharmaceutical challenges, including the low solubility, polymorphism, and bioavailability of drugs. It also provides insights into the development of the biologically functionalized ionic liquids suitable for medical and pharmaceutical applications. Ionic liquids have been used as potential solvents or materials in the fields of pharmaceutical drug delivery and formulations because of their unique and tunable physicochemical and biological properties. Readers find explanations of the diverse approaches to the application of ionic liquids in drug solubility, active pharmaceutical ingredient (API) formulation, and drug delivery systems, such as topical, transdermal, and oral delivery, with particular emphasis on recent developments. Particular attention is given to the development of ionic liquid-assisted effective drug delivery techniques for sparingly soluble or insoluble drug molecules. This book also discusses the biological activities of ionic liquids for possible applications in drug formulation and drug delivery systems. Scientists in disciplines such as chemistry, biology, and pharmaceutics find this book instructive and informative for developing ionic liquid-based drug formulations or drug delivery systems.

After the Nancy Cruzan case was decided by the Supreme Court in 1990, and ultimately resolved by the Courts of the State of Missouri, the decision to withhold or withdraw life-prolonging nutrition and hydration appeared to many to be as noncontroversial as decisions to refuse respirators or dialysis. Even the Catholic Church held that, although there should be a presumption in favor of providing nutrition and hydration, the patient or the patient's surrogate could overrule this presumption, if either believed the treatment was disproportionate or burdensome. The Schiavo case changed all that. Although the decision to remove Terri Schiavo's nutrition and hydration was made by her husband - her legal surrogate - based on his wife's belief that such treatment was disproportionate, Schiavo's immediate family protested so much that the case took years to resolve. It eventually involved all branches of government at both the state and federal levels. The ethical dilemmas that such cases pose continue to stir great controversy. This in-depth examination of these dilemmas provides information and documentation from many perspectives. The editors have included a foreword by Dr. Jay Wolfson, Terri Schiavo's court-appointed guardian ad litem, as well as Dr. Wolfson's report to Gov. Jeb Bush on the case and Gov. Bush's reply; public statements by President George Bush and Senators David Weldon, Rick Santorum, Tom DeLay, Bill Frist, and Barney Frank; statements by the pope and other representatives of the Catholic Church on this issue; plus much medical and legal background material on both precedents to the Schiavo case and its aftermath, including the results of the autopsy report. For anyone wishing an in-depth understanding of these complex ethical issues, issues many of us will have to confront in our own families, this volume is indispensable.

This book introduces the new concept of "nanozyme", which refers to nanomaterials with intrinsic enzymatic activity, rather than nanomaterials with biological enzymes incorporated on the surface. The book presents the cutting-edge advances in nanozyme, with emphasis on state-of-the-art applications in many important fields, such as in the biomedical fields and for environmental protection. The nanozyme is a totally new type of artificial enzyme and exhibits huge advantages over natural enzymes, including greater stability, low cost, versatility, simplicity, and suitability for industry. It is of interest to university researchers, R&D engineers, as well as graduate students in nanoscience and technology, and biology wishing to learn the core principles, methods, and the corresponding applications of "nanozyme".

Turbulent changes in worldwide economies and decreases in overall quality of life have led to a re-evaluation of the current state of health services. Improvements in this sector will allow for more efficient healthcare delivery to the public, as well as increased patient satisfaction. Effective Methods for Modern Healthcare Service Quality and Evaluation is an authoritative reference source for the latest research on emerging tools and methodologies for the design of healthcare models, providing expert analyses on trouble-shooting specific problems in the industry and creating optimal hospital environments. Highlighting various perspectives across a range of relevant health services, this book is ideally designed for policy makers, researchers, upper-level students, and practitioners.

Stress is the leading cause of neck pain-and popping a pill is not the answer. Using the tools and techniques taught here, you can prevent neck pain and headaches in just minutes a day. Author Rowlin L. Lichter, M.D., is a board-certified orthopedic surgeon who shares step-by-step instructions on how you can stop your neck pain and headaches simply, quickly, and easily. Dr. Lichter has created a system of easy exercises that have provided permanent relief to 85 percent of the patients who tried them. Now this cure is yours without a prescription These techniques have been developed with the help of physical therapists at CHART Rehabilitation in Hawaii, with continuing success. Knowledgeable doctors and therapists worldwide have adopted these methods. Dr. Lichter also explores complementary and alternative medicine (CAM) therapies, like acupuncture and many kinds of massage and shiatsu, which can give temporary relief. Since most neck pains are transient, that may be all the help you need. He also offers his professional opinion on which treatments, products, and "miracle solutions" to avoid. These exercises offer permanent relief from more serious neck pain and can be an important upgrade to any healthy lifestyle.

Palliative and End-of-Life Care, 2nd Edition provides clinicians with the guidelines and tools necessary to provide quality, evidenced-based care to patients with life-limiting illness. This text describes the care and management of patients with advanced disease throughout the disease trajectory, extending from diagnosis of advanced disease until death. Four units provide the general principles of palliative and end-of-life care, important concepts, advanced disease management, and clinical practice guidelines. Clinical practice guidelines offer in-depth discussions of the pathophysiology of 19 different symptoms, interventions for specific symptom management (including in-depth rationales), and suggestions for patient and family teaching. Defines dying as a normal, healthy process aided by the support of an interdisciplinary team. Provides in-depth pathophysiology, assessment, and intervention information based upon the disease trajectory. Highlights opportunities for patient and family teaching. Describes psychosocial issues experienced by patients and their families. Reviews uncomplicated and complicated grief and mourning, providing suggestions to help the family after a patient's death. Includes case studies at the end of chapters to reinforce key concepts of compassionate care. New chapters including Advance Care Planning, Ethical Issues, Spiritual Care Across Cultures, Pharmacology, Sleep, and Nutrition. Includes a new appendix on Assessment Tools and Resources for more comprehensive coverage of palliative and end-of-life care.

Non-linear phenomena pervade the pharmaceutical sciences. Understanding the interface between each of these phenomena and the way in which they contribute to overarching processes such as pharmaceutical product development may ultimately result in more efficient, less costly and rapid implementation. The benefit to Society is self-evident in that affordable treatments would be rapidly forthcoming. We have aggregated these phenomena into one topic "Pharmaco-complexity: Non-linear Phenomena and Drug Product Development".

This book (hardcover) is part of the TREDITION CLASSICS. It contains classical literature works from over two thousand years. Most of these titles have been out of print and off the bookstore shelves for decades. The book series is intended to preserve the cultural legacy and to promote the timeless works of classical literature. Readers of a TREDITION CLASSICS book support the mission to save many of the amazing works of world literature from oblivion. With this series, tredition intends to make thousands of international literature classics available in printed format again - worldwide.

Natural compounds obtained from plants represent a tremendous global market due to their use as food additives, cosmetics, in agriculture and in pharmaceuticals. This book provides up-to-date information on various strategies and methods for producing compounds of interest. Leading researchers discuss the latest advances in environmentally friendly natural compound production from plants, making the book a valuable resource for biotechnologists, pharmacists, food technologists and researchers working in the medical and healthcare industries.

This book focuses on various aspects of research on ageing, including in relation to assistive technology; dignity of aging; how technology can support a greater understanding of the experience of physically aging and cognitive changes; mobility issues associated with the elderly; and emerging technologies. The 80+ age group represents an expanding market, with an estimated worth of GBP21.4 billion a year. Everyone is affected by this shift in demographics - we are getting older and may become carers - and we need to prepare ourselves and adjust our surroundings for longer life. Products, services and environments have been changing in response to the changing population. Presenting international design research to demonstrate the thinking and ideas shaping design, this book is a valuable resource for designers; product developers; employers; gerontologists; and medical, health and service providers; as well as everyone interested in aging.

This book concerns issues related to biomathematics, medicine, or cybernetics as practiced by engineers. Considered population dynamics models are still in the interest of researchers, and even this interest is increasing, especially now in the time of SARS-CoV-2 coronavirus pandemic, when models are intensively studied in order to help predict its behaviour within human population. The structures of population dynamics models and practical methods of finding their solutions are discussed. Finally, the hypothesis of the existence of non-trivial ergodic properties of the model of erythropoietic response dynamics formulated by A. Lasota in the form of delay differential equation with unimodal feedback is analysed. The research can be compared with actual medical data, as well as shows that the structures of population models can reflect the dynamic structures of reality.

Written by emergency nurses for emergency nurses, this comprehensive, evidence-based resource covers the issues and procedures that are often unique to the emergency department. New developments and changes in clinical practice are incorporated throughout. The user-friendly format features more than 350 high-quality illustrations and 150 tables that highlight essential concepts and offer quick access to vital information. Key coverage includes clinical fundamentals, treatment for trauma and medical-surgical emergencies, the foundations of emergency nursing practice, and special populations. 58 contributors offer valuable insights from a broad range of clinical positions in rural, suburban, and urban areas. High-quality radiographs and other diagnostic images help you learn to identify common conditions - especially head trauma, fractures, and dislocations. Logically organized, chapters are grouped into six sections for quick access to important content: Foundations of Emergency Nursing, Professional Practice, Clinical Foundations of Emergency Nursing, Major Trauma Emergencies, Medical and Surgical Emergencies, and Special Patient Populations. Tables and boxes highlight and summarize critical information for at-a-glance reference. A separate unit on special patient populations covers topics such as child abuse, elder abuse, intimate partner violence, sexual assault, substance abuse and behavioral/pediatric/obstetrical emergencies. Priority nursing diagnoses are highlighted in a quick-reference appendix to help you focus on the most serious problems. Five new chapters bring you the most reliable, up-to-date information on these key topics: Management of the Critical Care Patient in the Emergency Department Family Presence During Resuscitation Forensic Nursing Nuclear, Biological, and Chemical Agents of Mass Destruction Influenza: Seasonal, Avian, and Pandemic Expanded coverage of shock and sepsis provides essential information on pathophysiology and diagnosis, with valuable guidelines for managing these patients. A detailed discussion of various types of triage systems and triage acuity ratings examines valid and reliable methods for differentiating between patients who require immediate treatment and those who can wait. Additional coverage of behavioral health emergencies includes new information on agitation, substance abuse, and suicide prevention.

There is very little discussion of socially just approaches to speech-language pathology. Within other fields of clinically-oriented practice that social justice is a topic that has received a great deal of attention within the last few years. Pedagogy for addressing social justice has been developed in other disciplines. Within the field of communication disorders, it has failed to move forward and do the same. Discussion of social justice is important given the current sociopolitical climate and landscape that clients carry out in their day-to-day functioning. Speech-language pathologists (SLPs) have an opportunity to engage in practices that help address and alleviate some of the injustices that contribute to educational and health disparities experienced by communities of color. They may do this through the development and application of a socially just orientation of culturally competent practice that fosters changes beyond the individual level. Adapting such a framework makes it possible for SLPs to effectively advocate for and foster equity and inclusion for the individuals and broader communities impacted by SLP services. Critical Perspectives on Social Justice in Speech-Language Pathology addresses the socio-political contexts of how the field of speech-language pathology and service delivery can impact policy and debates related to social justice issues. It explores social position factors and the experiences of marginalized communities to explore how speech-language pathologists deliver services, train and prepare students, and carry out research in communities of color. It covers topic areas including disproportionality in special education, disability rights and ableism, achievement and opportunity gaps, health disparities, and LGBTQ+ rights with a focus on voice, communication, and gender-diverse populations. This book is essential for speech-language pathologists, administrators, practitioners, researchers, academicians, and students interested in how the SLP profession and discipline can contribute to or develop efforts to help address injustices faced by Black, Indigenous, and people of color (BIPOC) communities.

This issue of Physical Medicine and Rehabilitation Clinics, guest edited by Dr. Aloysia L. Schwabe, will cover a number of important topics related to Cerebral Palsy. This issue is one of four each year selected by our series Consulting Editor, Dr. Santos Martinez. Articles in this issue include but are not limited to: Comprehensive Care in CP, The Expanding Role of Genetics in CP, Musculoskeletal Imaging in CP, Updates in Medical Management of Hypertonia, Biomechanics and Lower Limb Bracing, Surgical tone Reduction In CP, Motion Analysis in Pre-operative Surgical Planning, Technological Advances in CP Rehabilitation, Adaptive Sports and Recreation, Transition, Adult Orthopedic Issues in CP, and CPRN.

Clinical and Basic Neurogastroenterology and Motility is a state-of-the-art, lucidly written, generously illustrated, landmark publication that comprehensively addresses the underlying mechanisms and management of common adult and pediatric motility disorders. These problems affect 50% of the population and include conditions such as dysphagia, achalasia, gastroesophageal reflux disease, gastroparesis, irritable bowel syndrome (IBS), gas and bloating, SIBO, constipation and fecal incontinence. The book brings together international experts and clinician scientists, epitomizing their years of wisdom into a concise yet practical text that is delivered in two distinct sections, basic and clinical. It fulfills a large unmet need, and bridges a long-awaited knowledge gap among trainees, clinicians, scientists, nurses and technicians, earnestly engaged in this field.

Written by expert pediatric nurse practitioners, this resource is a fully endorsed compendium of essential information. Using an easy-to-use outline format, it defines the parameters of the specialty by outlining the entire scope of PNP practice and covers everything in the Pediatric Nurse Practitioners (PNP) certification exams. In light of the increase in the number of PNP programs and students seeking certification, Core Curriculum for Primary Pediatric Nurse Practitioners offers the big-picture view that every PNP needs. Authored and endorsed by the National Association of Pediatric Nurse Practitioners (NAPNAP) and the Association of Faculties of Pediatric Nurse Practitioners (AFPNP). Chapters that cover the continuum of PNP practice, such as the Role of the PNP, Wellness Issues, Growth and Development, Genetics, diagnosing and managing Common Illnesses and Chronic Conditions, Pediatric Emergencies, Pharmacology, and Treatment Guides. Concise outline format is accessible and user-friendly. Covers all content on both the ANCB and ANCC certification exams

This book provides the first presentation of the state-of-the-art in the application of modern Neuroscience research in predicting, preventing and alleviating the negative sequelae of neurodevelopmental, acquired, or neurodegenerative brain abnormalities on speech and language. To this end, this edited volume brings together contributions from several leading experts in a markedly broad range of disciplines, comprising Neurology, Neurosurgery, Genetics, Engineering, Neuroimaging and Neurostimulation, Neuropsychology, and Speech and Language Therapy.