From the wooden teeth of George Washington to the Bly prosthesis, popular in the 1860s and boasting easy uniform motions of the limb, to today's lifelike approximations, prosthetic devices reveal the extent to which the evolution and design of technologies of the body are intertwined with both the practical and subjective needs of human beings.

The peculiar history of prosthetic devices sheds light on the relationship between technological change and the civilizing process of modernity, and analyzes the concrete materials of prosthetics which carry with them ideologies of body, ideals, body politics, and culture.

Simultaneously critiquing, historicizing, and theorizing prosthetics, Artificial Parts, Practical Lives lays out a balanced and complex picture of its subject, neither vilifying nor celebrating the merger of flesh and machine.

No longer confined to medical devices, medical software has become a pervasive technology giving healthcare operators access to clinical information stored in electronic health records and clinical decision support systems, supporting robot-assisted telesurgery, and providing the technology behind ambient assisted living. These systems and software must be designed, built and maintained according to strict regulations and standards to ensure that they are safe, reliable and secure. Engineering High Quality Medical Software illustrates how to exploit techniques, methodologies, development processes and existing standards to realize high-confidence medical software. After an introductory survey of the topic the book covers global regulations and standards (including EU MDD 93/42/EEC, FDA Title 21 of US CFR, ISO 13485, ISO 14971, IEC 52304, IEEE 1012 and ISO/IEC 29119), verification and validation techniques and techniques, and methodologies and engineering tasks for the development, configuration and maintenance of medical software.

Author of AP's bestselling "Therapist's Guide to Clinical Intervention" now turns her attention to substance abuse intervention. The book will follow a similar format to her previous book, presenting information in easy to read outline form, with relevant forms, patient questionnaires, checklists, business documents, etc.
Part I discusses the social impact of substance abuse and provides a general overview of the physiological and psychological characteristics of abuse, DSM IV definition of abuse, and classifications of the varying types of drugs. Part II is the main section of the book and covers assessment, different stages of abuse/recovery, and treatment choices. Coverage includes the discussion of myriad self help choices (e.g. AA), group therapy, brief therapy, and more. Discussion will also include making a determination of treatment as inpatient or outpatient, and issues relevant to special populations (teenagers, geriatrics, comorbidity patients, etc.). Part III presents skill building resources. Part IV covers prevention, quality assurance, and also includes a glossary.
* Outlines treatment goals and objectives
* Outlines for assessing special circumstances
* Offers skill building resources to supplement treatment

This book covers multi-scale biomechanics for oncology, ranging from cells and tissues to whole organ. Topics covered include, but not limited to, biomaterials in mechano-oncology, non-invasive imaging techniques, mechanical models of cell migration, cancer cell mechanics, and platelet-based drug delivery for cancer applications. This is an ideal book for graduate students, biomedical engineers, and researchers in the field of mechanobiology and oncology. This book also: Describes how mechanical properties of cancer cells, the extracellular matrix, tumor microenvironment and immuno-editing, and fluid flow dynamics contribute to tumor progression and the metastatic process Provides the latest research on non-invasive imaging, including traction force microscopy and brillouin confocal microscopy Includes insight into NCIs' role in supporting biomechanics in oncology research Details how biomaterials in mechano-oncology can be used as a means to tune materials to study cancer

This book introduces "network pharmacology" as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.

This treatment-oriented guide provides a hands-on approach to the diagnosis and management of swallowing disorders. The material focuses on developing skills that lead to basic clinical decisions regarding dysphagic patients. Written for students and practitioners who are new to the field, the text begins with the anatomy and physiology of swallowing and goes on to cover the range of swallowing disorders, the clinical and laboratory examination, and treatment strategies. The authors have national reputations as leaders in this area and readers are sure to benefit from their expert clinical tips provided in the manual. Provides essential coverage of the range of swallowing disorders, the clinical and laboratory examination, and treatment strategies. Includes expert clinical tips from the authors who are nationally recognized as leaders in the field. Offers a hands-on, treatment-oriented approach to the diagnosis and management of swallowing disorders. Pedagogical features include Take Home Notes, Case Studies, Chapter Terms, and Chapter Review Questions. Chapters are easily treated as separate lecture topics, making this text ideal for classroom use. One-of-a-kind, entry-level text provides balanced coverage of the full spectrum of knowledge needed to prepare one entering the field of dysphagia management.

Guest edited by Dr. Jeffrey Shook, this issue of Clinics in Podiatric Medicine and Surgery will cover several key areas of interest related to Perioperative Considerations in the Surgical Patient. This issue is one of four selected each year by our series Consulting Editor, Dr. Thomas Chang. Articles in this issue include, but are not limited to: Surgical Consent, Medical Consultation, Prevention of Deep Venous Thromboembolism, Prophylactic Antibiosis, Preoperative Assessment and Perioperative Management of Pulmonary Disease, Preoperative Evaluation of the Pediatric Patient, The Geriatric Patient, Postoperative Convalescence, Perioperative pain management, Preoperative Evaluation and Management of Peripheral Arterial Disease, Preoperative Assessment of the Cardiac Patient, Surgery in the Patient with Renal Disease, and Evaluation and Perioperative Management of the Diabetic Patient.

Get a quick, expert overview of best practices for diagnosis and treatment of eating disorders in children and adolescents. This concise resource by Drs. Johannes Hebebrand and Beate Herpertz-Dahlmann provides psychiatrists and pediatricians with current information in this increasingly important field, including practical sections on developmental aspects of eating disorders, symptomology, epidemiology, etiology and pathyphysiology, treatment and outcomes, and prevention. Discusses general concepts for feeding, eating, and weight disorders; body weight and composition, appetite regulation, and the emergence of body perception and image. Covers genetics of eating and weight disorders, influence of hormones, intergenerational effects, and food addiction. Includes information on cognitive behavioral therapy, family-based therapies, early intervention, pharmacotherapy, bariatric surgery, and other treatments. Consolidates today's available information on this timely topic into a single convenient resource.

Plant endophytes are a potential source for the production of bioactive compounds that can fight against devastating diseases in both plants and humans. Among these endophytic microorganisms, endophytic fungi are one of the dominant group of microorganisms with a potential role in plant growth promotion and the discovery of noble bioactive natural products. Endophytic fungi possess several bioactivities like anticancer, antimicrobial, insecticidal, plant growth stimulants, crop protection, phytoremediation, etc. Presence of modular biosynthetic genes clusters like PKS and NRPS in several endophytic fungi underscores the need to understand and explore such organisms. This volume presents and demonstrates the applied aspects of endophytic fungi. Practical applications of such endophytes are discussed in detail, including studies in pharmaceutical development and agricultural management of important microbial diseases. The beneficial effects that endophytic fungi provide to host plants-enhancing growth, increasing fitness, strengthening tolerance to abiotic and biotic stresses through secondary metabolites-are also discussed. The reader is provided with a comprehensive and detailed understanding of such relationships between endophytic fungi and their host.

This book gathers selected studies on the industrial applications of glycoside hydrolases (GHs), presenting an updated classification of these enzymes, and discussing their structure, mechanisms, and various approaches to improve their catalytic efficiency. Further, it explains the various industrial applications of glycoside hydrolases in food, effluent treatment, biofuel production, and the paper and pulp industries. Lastly, the book provides a comparative analysis of glycoside hydrolases and discusses the role of metagenomics in the discovery of industrially important enzymes. As such it is a thought-provoking, instructive and informative resource for biochemists, enzymologists, molecular biologists and bioprocess technologists.

Traditionally, nursing is acknowledged as a caring profession and is associated with advocating for others. However, incivility is increasingly occurring amongst nurses, both in the clinical and academic environments, and is causing affected nurses both psychological and physical harm. Incivility Among Nursing Professionals in Clinical and Academic Environments: Emerging Research and Opportunities provides emerging views and consequences surrounding workplace bullying in the healthcare profession including recognizing the signs and symptoms of incivility in the workplace, identifying ways in which affected nurses can seek help, and examining healthy methods of coping with the incivility. Featuring coverage on a broad range of topics such as human resources, therapy, and clinical nursing, this book is ideally designed for nurses, managers, healthcare workers and consumers, hospital and clinical staff, researchers, students, and policymakers.

This book explores Ireland's Marriage Bar, examining its impact on women's lives and the predominantly feminised nursing profession. Information on the history of nursing and the evolution of the nursing profession tends to focus on critical events or key persons who shaped the profession. What is less known and explored is the women nurses' work experiences or how the world outside the ward affected the nurse and the nursing profession at moments in time. This book takes one of these moments in time, the period of the Marriage Bar, and examines the women nurses' lives and the nursing profession during this period of Ireland's history. It does so by adopting a historical perspective and a lived experience perspective of women who had to negotiate this practice. Fifty years on from the Bar removal, as remnants of this time in Ireland's history remain, legislative and constitutional change are required to right the wrongs of the past.

This issue of Clinics in Podiatric Medicine and Surgery, guest edited by Dr. Guido LaPorta, will discuss several important, recent Innovations in Foot and Ankle Surgery. Topics covered include: The Subchondroplasty (SCP) Procedure for Chronic Bone Lesions, Sonic Pin & Sonic Anchor, Total Talus Replacement, Minimally Invasive Bunion Correction, Trabecular Metal Wedges and Custom 3D Printed Implants, Fundamentals and Classification of Hexapod Surgery, Biomechanical Considerations for Circular External Fixation, Essentials of Deformity Planning, Gradual Equinus Correction, Midfoot Charcot Reconstruction, and Complex Deformity Correction, among others.

This book commemorates the scientific contributions of distinguished statistician, Andrei Yakovlev. It reflects upon Dr. Yakovlev's many research interests including stochastic modeling and the analysis of micro-array data, and throughout the book it emphasizes applications of the theory in biology, medicine and public health. The contributions to this volume are divided into two parts. Part A consists of original research articles, which can be roughly grouped into four thematic areas: (i) branching processes, especially as models for cell kinetics, (ii) multiple testing issues as they arise in the analysis of biologic data, (iii) applications of mathematical models and of new inferential techniques in epidemiology, and (iv) contributions to statistical methodology, with an emphasis on the modeling and analysis of survival time data. Part B consists of methodological research reported as a short communication, ending with some personal reflections on research fields associated with Andrei and on his approach to science. The Appendix contains an abbreviated vitae and a list of Andrei's publications, complete as far as we know. The contributions in this book are written by Dr. Yakovlev's collaborators and notable statisticians including former presidents of the Institute of Mathematical Statistics and of the Statistics Section of the AAAS. Dr. Yakovlev's research appeared in four books and almost 200 scientific papers, in mathematics, statistics, biomathematics and biology journals. Ultimately this book offers a tribute to Dr. Yakovlev's work and recognizes the legacy of his contributions in the biostatistics community.

Medical breakthroughs and adult literacy have made it easier than ever before to acquire the knowledge, skills, and values needed to lead a productive and satisfying life, yet many Americans have difficulty understanding and acting upon the health information they acquire. The Handbook of Research on Adult and Community Health Education: Tools, Trends, and Methodologies presents educational and social science perspectives on the state of the healthcare industry and the information technologies surrounding it. It presents a collection of the latest research on methods, programs, and procedures practiced by health literate societies. This groundbreaking compilation provides cutting-edge content for researchers, social scientists, academicians, and adult educators and learners interested in how available technologies affect our health today.

This book presents peer-reviewed articles from the 20th International Symposium on Optomechatronic Technologies (ISOT 2019), held in Goa, India. The symposium brought together students, researchers, professionals, and academicians in the field of optomechatronics and related areas on a common platform conducive to academic interaction with business professionals.