This volume, is developed from a collaborative study sponsored by the World Health Organization over a period of five years, the result of the combined effort of over 30 experts working in 19 different countries. The book presents a comprehensive survey of the development, policy, and procedures of methadone maintenance in countries with experience in this treatment. In addition to presenting a general overview of methadone's role in treating opioid addiction, the volume also focuses on specific questions of current interest, particularly the critical issue of methadone maintenance in the prevention of AIDS. Public health specialists and policymakers will find this book an invaluable source of information about what can be expected from methadone maintenance programs and why such programs have achieved some success in the rehabilitation of opiate users, while so many other attempts in this area have failed.

Following an introductory chapter, the contributors look at the impact of AIDS epidemiology on methadone policy. The role of methadone in addressing intravenous drug abuse and unsafe sex practices in drug dependent persons is explored in an attempt to assess the ability of methadone maintenance programs to stem the spread of AIDS. Subsequent chapters review the world literature on methadone in treating opioid dependency, explore national policies and practices regarding methadone maintenance, present an international survey of methadone's role, and analyze the present state of research on methadone. A bibliography and index complete the volume.

This book discusses the design and implementation of energy harvesting systems targeting wearable devices. The authors describe in detail the different energy harvesting sources that can be utilized for powering low-power devices in general, focusing on the best candidates for wearable applications. Coverage also includes state-of-the-art interface circuits, which can be used to accept energy from harvesters and deliver it to a device in the most efficient way. Finally, the authors present power management circuits for using multiple energy harvesting sources at the same time to power devices and to enhance efficiency of the system.

This book presents regenerative strategies for the treatment of knee joint disabilities. The book is composed of four main sections totaling 19 chapters which review the current knowledge on the clinical management and preclinical regenerative strategies. It examines the role of different natural-based biomaterials as scaffolds and implants for addressing different tissue lesions in the knee joint. Section one provides an updated and comprehensive discussion on articular cartilage tissue regeneration. Section two focuses on the important contributions for bone and osteochondral tissue engineering. Section three overview the recent advances on meniscus repair/regeneration strategies. Finally, section four further discusses the current strategies for treatment of ligament lesions. Each chapter is prepared by world know expert on their fields, so we do firmly believe that the proposed book will be a reference in the area of biomaterials for regenerative medicine.

Meticulously updated by board-certified oral and maxillofacial radiologist, Dr. Dania Tamimi and her team of sub-specialty experts, Specialty Imaging: Temporomandibular Joint and Sleep-Disordered Breathing, second edition, is a comprehensive reference ideal for anyone involved with TMJ imaging or SDB, including oral and maxillofacial radiologists and surgeons, TMJ/craniofacial pain specialists, sleep medicine specialists, head and neck radiologists, and otolaryngologists. This detailed, beautifully illustrated volume covers recent advances in the diagnosis and treatment of both the TMJ and SDB, including how related structures are affected. Employing a multifaceted, multispecialty approach, the clinical perspectives and imaging expertise of today's research specialists are brought together in a single, image-rich, easy-to-read text. Reflects the current emphasis on holistic diagnosis and treatment not just of the TMJ but of all related structures that can be adversely affected by any TMJ dysfunction  Examines a variety of presenting clinical signs or symptoms, discusses imaging strategies and  the associated conditions revealed by imaging, and helps you develop differential diagnoses  Provides current, detailed information on the relationship between TMJ disorders and SDB, how imaging shows the correlation between the two, and risk factors for SDB  Includes upper respiratory tract diagnoses, with multiple subsections on the nasal cavity, paranasal sinuses, nasopharynx, oropharynx, and hypopharynx, each with multiple new chapters  Features new chapters on ultrasonography of the TMJ and upper respiratory tract, new content on 3D and 4D modeling and surface rendering, a new section on imaging of upper respiratory tract procedures, and new content detailing the tie-in between occlusion and SDB  Includes an expanded Modalities section that includes new chapters on formulating a TMJ/upper respiratory tract report; plain film imaging of the TMJ and upper respiratory tract; CBCT analysis of the upper respiratory tract; dynamic MR of the TMJ and upper respiratory tract, and ultrasound of the TMJ   Covers the role that TMJ plays in facial growth and development, stomatognathic system function, and how TMJ abnormalities change the dimensions of the facial skeleton and surrounding structures  Contains over 5,000 print and online-only images (more than 300 are new), including radiologic images, full-color medical illustrations, and histologic and gross pathology photographs  Reflects updates to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC-TMD)-the major clinical classification method and a key tool to assess/diagnose TMJ issues and facilitate communication for consultants, referrals, and prognoses  Includes an eBook version?that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud 

Sports Rehabilitation is a multi-disciplinary approach to treat injuries sustained through sports participation so the athlete can regain normal pain-free mobility. The primary goal is to return to pre-injury activities, whether the athlete is a professional, amateur or casual player. Articles to include ACL/Knee rehabilitation, Foot Intrinsics and Balance, Hamstring rehabilitation in runners, Rehabilitation of the throwing athlete, Concussion rehabilitation and many more!

How has technology changed the art and science of nursing practice? Many facets of nursing practice have stayed constant over the years such as the way we advocate for our patients and the art of caring for our patients. However, nursing practice has evolved over the years especially in the bedside delivery of state of the art nursing care. Technology at the bedside has forced nurse educators to change the ways in which we always have taught nursing students. Technology has also begun to change the methods used in the actual bedside nursing care. In this issue, you will hear from some of the nursing experts in areas of nursing care that has changed in either the delivery of care or method of assessing care of the patient. Nursing experts will describe some of the historical changes and intrigue you in the changes expected to come to the bedside. Why is this issue important? First, we gain insight from a review of where we have been and nurses tend to reminisce on our past as well as romance our historical roots. Second, technology is ever changing and it is good practice to keep abreast of what is happening in other areas of nursing so that we can apply others successes in our own specific areas of nursing. Third, informatics in nursing is a growing field and nursing must embrace technology and learn to adapt various methods of delivery so that we can appropriately care for and advocate for our patients. WWith the changes in our national healthcare system, we must encourage nurses to try out new methods of delivery as well as encourage their ideas of how nursing can change. The articles in this issue reflect these changes.

Art as Therapy introduces the theory and practice of art therapy in a concise, accessible and informative way. Tessa Dalley's introduction gives an overview of basic issues, research and development. Subsequent chapters, written by specialists, are chosen to demonstrate the ways in which art therapy can be applied to different client groups, in a variety of clinical settings. These include children, adolescents suffering from anorexia nervosa, the mentally handicapped, the elderly and terminally ill, those in psychiatric hospitals and prison inmates. Illustrated case studies provide visual explanations for the art therapy processes and the final chapter discusses training for the profession. Art as Therapy has been welcomed by art therapists, social workers, psychologists, nurses and teachers.

Describing the role of engineering in medicine today, this comprehensive volume covers a wide range of the most important topics in this burgeoning field. Supported with over 145 illustrations, the book discusses bioelectrical systems, mechanical analysis of biological tissues and organs, biomaterial selection, compartmental modeling, and biomedical instrumentation. Moreover, students and professionals find a thorough treatment of the concept of using living cells in various therapeutics and diagnostics. Structured as a complete text for courses on the subject, the book also makes a nice reference for professionals new to the bioengineering field.

This groundbreaking annual review has provided over three decades of knowledge, insight, and research on topics critical to the field of nursing. The 34th volume presents abundant new research devoted to examining and forwarding the field of modern ethics in nursing. It reflects the rapid acceleration of change in the roles and responsibilities of nurses and the concurrent need for reexamination of professional ethical values. Articles focus on creating nurses who are able to negotiate, adapt, and provide excellent care to patients as they take on greater administrative duties, rely more on technology, and assume some of the roles and responsibilities of physicians. Chapters are comprised of carefully selected articles that underscore the importance of in-depth ethical education and professional character development in the nursing classroom, and its continued evolution as nurses adapt to a changing health care environment throughout their careers. They include examples of contemporary health care dilemmas and how nurses have used ethical values to guide their behavior in situations where they encounter highy vulnerable patients; address ethical problems relating to family issues such as self-neglect and the wellbeing of children in military families; and the systems-of-care issues regarding genetics, smart home technologies for older adults, interprofessional collaboration, and post-deloyment reintegration. Key Topics: Nursing Ethics: A Lifelong Commitment Ethical Analysis of Family Impact of Mental Health Stigma Ethical issues in Family Care Ethical Considerations in Self-Neglect The Effects of Parental Service on teh WEllbeing of our Youngest Military Members Ethics of Genetics in Primary Care Ethics of Smart Home Technologies for Older Adults Post-Deployment Reintegration: The Ethics of Embodied Personal Presence and hte Formation of Military Meaning Ethical Issues Encountered by Military Nurses

The book presents an integrative review of paleoneurology, the study of endocranial morphology in fossil species. The main focus is on showing how computed methods can be used to support advances in evolutionary neuroanatomy, paleoanthropology and archaeology and how they have contributed to creating a completely new perspective in cognitive neuroscience. Moreover, thanks to its multidisciplinary approach, the book addresses students and researchers approaching human paleoneurology from different angles and for different purposes, such as biologists, physicians, anthropologists, archaeologists and computer scientists. The individual chapters, written by international experts, represent authoritative reviews of the most important topics in the field. All the concepts are presented in an easy-to-understand style, making them accessible to university students, newcomers and also to anyone interested in understanding how methods like biomedical imaging, digital anatomy and computed and multivariate morphometrics can be used for analyzing ontogenetic and phylogenetic changes according to the principles of functional morphology, morphological integration and modularity.

Anaerobiosis and Stemness: An evolutionary paradigm provides a context for understanding the many complexities and evolutionary features of stem cells and the clinical implications of anaerobiosis stem cells. Combining theoretical and experimental knowledge, the authors provide a broad understanding of how the absence or low concentration of oxygen can play an influential role in the maintenance and self-renewal of stem cells and stem cell differentiation. This understanding has clinical implications for the fields of regenerative medicine, cancer biology and transplantation, as well as cell engineering and cell therapy. Anaerobiosis and Stemness is an important resource for stem cell and developmental biologists alike, as well as oncologists, cancer biologists, and researchers using stem cells for regeneration.

How do doctors and nurses communicate with frightened patients who are dying, address the needs and concerns of the patients, and help the patients arrive at an acceptance of death? This work deals with the relationship that the health care team has with the dying and how well that team is prepared to address the fears of the dying. In addition, the health care team must learn to deal with their own emotions and ignorance concerning death. This work should be of interest to those professions that deal closely with dying people.

Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales - including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces - bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.

This book introduces the state-of-the-art technologies in mechatronics, robotics, and MEMS devices in order to improve their methodologies. It provides a follow-up to "Advanced Mechatronics and MEMS Devices" (2013) with an exploration of the most up-to-date technologies and their applications, shown through examples that give readers insights and lessons learned from actual projects. Researchers on mechatronics, robotics, and MEMS as well as graduate students in mechanical engineering will find chapters on: Fundamental design and working principles on MEMS accelerometers Innovative mobile technologies Force/tactile sensors development Control schemes for reconfigurable robotic systems Inertial microfluidics Piezoelectric force sensors and dynamic calibration techniques ...And more. Authors explore applications in the areas of agriculture, biomedicine, advanced manufacturing, and space. Micro-assembly for current and future industries is also considered, as well as the design and development of micro and intelligent manufacturing.

Growing up in a small mining town in New South Wales, Australia, during World War II, Beverley Keegan knew that she wanted to become a nurse. Her adventures began when she traveled on an overnight train to the big city of Sydney to commence her nursing training. Once she became a nurse, her working life continued for more than fifty years in various locations in Australia, New Guinea, and the Red Centre around Alice Springs.

"Television, Bedpans, and Me" tells the true story of the many adventures she encountered as she traveled around Australia during her nursing career. Her story follows the amazing growth of medicine from basic nursing in the fifties to the electronic age of today. At the same time, the advent of television followed her as she moved from state to state and from Sydney to the Australian Outback.

This memoir shares the journey taken by one woman, including humorous tales, pathos, and ordinary family occurrences that colour all of our lives, while tracing the development of the miracles of modern medicine. In "Television, Bedpans, and Me," Keegan lovingly recounts her experiences as a registered nurse and recalls the people she has nursed and worked with for over half a century.

This book discusses a novel and high-rate-capable micro pattern gaseous detector of the Micromegas (MICRO-MEsh GAS detector) type. It provides a detailed characterization of the performance of Micromegas detectors on the basis of measurements and simulations, along with an in-depth examination of analysis and reconstruction methods. The accurate and efficient detection of minimum ionizing particles in high-rate background environments is demonstrated. The excellent performance determined here for these lightweight detectors will make possible the live medical imaging of a patient during ion-beam treatment.

APRNs are essential to deliver healthcare in today's complex environment. Certified Registered Nurse Anesthetists have met that challenge for over 150 years. Nurse Anesthetists have shifted from the intensive care unit as critical care nurses into the operating room arena. The operating room is an environment that is uniquely challenging. A critical care background is essential to meet these challenges, and all Certified Registered Nurse Anesthetists share that experience. The topic; "Certified Registered Nurse Anesthesia: Critical Care Nursing in the Operating Room", highlights critical care nursing as it is applied in the operating room setting. Critical care nurses will appreciate the knowledge base that is essential for the anesthetist. As healthcare reform demands greater efficiency, more and more procedures are performed outside the operating room. The line between the Operating Room, ICU and Interventional Radiology will become less defined. Critical care nurses are, and will be more involved in patient care while an anesthetic is administered. It is the goal of this proposed monograph to share knowledge and experience so that ICU nurses will learn more about caring for the anesthetized patient.

The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. The chapter "Polymeric Nanoparticle-Mediated Gene Delivery for Lung Cancer Treatment" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This book offers a succinct but comprehensive description of the mechanics of muscle contraction and legged terrestrial locomotion. It describes on the one hand how the fundamental properties of muscle tissue affect the mechanics of locomotion, and on the other, how the mechanics of locomotion modify the mechanism of muscle operation under different conditions. Further, the book reports on the design and results of experiments conducted with two goals. The first was to describe the physiological function of muscle tissue (which may be considered as the "motor") contracting at a constant length, during shortening, during lengthening, and under a condition that occurs most frequently in the back-and-forth movement of the limbs during locomotion, namely the stretch-shortening cycle of the active muscle. The second objective was to analyze the interaction between the motor and the "machine" (the skeletal lever system) during walking and running in different scenarios with respect to speed, step frequency, body mass, gravity, age, and pathological gait. The book will be of considerable interest to physiology, biology and physics students, and provides researchers with stimuli for further experimental and analytical work.