This issue of Sleep Medicine Clinics focuses on Sleep in Older Adults, with topics including: Sleep in Normal Aging; Insomnia in the Older Adult; Sleep Apnea in the Older Adult; Circadian Rhythm Sleep-Wake Disorders in the Older Adult; Restless Legs Syndrome; Periodic Limb Movement Disorder and Other Sleep Related Movement Disorders in the Older Adult; REM Sleep Behavior Disorder and Other Parasomnias in the Older Adult; Neurodegenerative Disorders and Sleep; Medical Conditions and Sleep in the Older Adult; Psychiatric Illness and Sleep in the Older Adult; Sleep and Cognition in the Older Adult; Sleep and Nocturia in the Older Adult; Sleep and Long Term Care; and Sleep in the Hospitalized Older Adult.

Nanostructures for the Engineering of Cells: Tissues and Organs showcases recent advances in pharmaceutical nanotechnology, with particular emphasis on tissue engineering, organ and cell applications. The book provides an up-to-date overview of organ targeting and cell targeting using nanotechnology. In addition, tissue engineering applications, such as skin regeneration are also discussed. Written by a diverse range of international academics, this book is a valuable research resource for researchers working in the biomaterials, medical and pharmaceutical industries.

Offers comprehensive guidance for practitioners, students, and researchers in psychology, psychiatry, and counseling to teach relaxation to clients. Two clinical psychologists widely known for their writings on relaxation present state-of-the-art methods for teaching clients to ease muscle and mind tension to deal with stress and anxiety disorders, as well as other conditions where stress and anxiety play a role. Bernstein and Hazlett-Stevens explain who the targets for Progressive Relaxation Training (PRT) are; the rationale, basic procedures, and variations of PRT; the setting and possible problems and solutions of PRT; and how to assess a client's progress. They also address hypnosis, drugs, and PRT, as well as PRT used in a mindfulness-based clinical practice. Case studies and evaluative research in PRT are also included. Students and practitioners in psychology, psychiatry, and counseling will find this work of interest. This book may also be useful supplemental reading for behavior modification courses and practicum courses in behavior therapy. Case studies illustrate techniques Research included shows the benefits of PRT Comprehensive coverage includes rationale, physiology, procedures, variations, problems and solutions, and assessment of progress Descriptions of recent neuroscience research show how PRT correlates in the brain

Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong focus on polymeric biomaterials, the book first reviews the major issues associated with PEGylation and its use in vivo. Chapters then focus on alternative polymer systems for drug delivery systems. Finally, nanoparticles and future perspectives are examined. This book is a valuable resource for scientists and researchers in biomaterials, pharmaceuticals and nanotechnology, and all those who wish to broaden their knowledge in this field.

Global Air Pollution in Aging: Reading Smoke Signals is a complete reference connecting environmental pollution research to the human aging process. Since 1800, lifespans have more than doubled as infections declined and medicine improved. But the 20th century introduced a new global scourge of air pollution from fossil fuels with the potential to damage arteries, hearts and lungs that has been related to chronic exposure of air pollution from fossil fuels. Risk areas of study include childhood obesity, brain damage associated with air pollution, increased risk for autism in children and dementia in older adults. In humans and animals, air pollution stimulates chronic inflammation in different organs, and genetic vulnerability to air pollution is being recognized, particularly for carriers of the Alzheimer risk gene ApoE4.

This expert compendium surveys the current state of military psychology across the branches of service at the clinical, research, consulting, and organizational levels. Its practical focus examines psychological adjustment pre- and post-deployment, commonly-encountered conditions (e.g., substance abuse), and the promotion of well-being, sleep, mindfulness, and resilience training. Coverage pays particular attention to uses of psychology in selection and assessment of service personnel in specialized positions, and training concerns for clinicians and students choosing to work with the military community. Chapters also address topics of particular salience to a socially conscious military, including PTSD, sexual harassment and assault, women's and LGBT issues, suicide prevention, and professional ethics. Among the specific chapters topics covered: * Military deployment psychology: psychologists in the forward environment. * Stress and resilience in married military couples. * Assessment and selection of high-risk operational personnel: processes, procedures, and underlying theoretical constructs. * Understanding and addressing sexual harassment and sexual assault in the US military. * Virtual reality applications for the assessment and treatment of PTSD. * Plus international perspectives on military psychology from China, Australia, India, and more. Grounding its readers in up-to-date research and practice, Military Psychology will assist health psychologists, clinical psychologists, psychiatrists, and clinical social workers in understanding and providing treatment for military populations, veterans, and their families, as well as military psychologists in leadership and consulting positions.

The book reports on advanced topics in interactive robotics research and practice; in particular, it addresses non-technical obstacles to the broadest uptake of these technologies. It focuses on new technologies that can physically and cognitively interact with humans, including neural interfaces, soft wearable robots, and sensor and actuator technologies; further, it discusses important regulatory challenges, including but not limited to business models, standardization, education and ethical-legal-socioeconomic issues. Gathering the outcomes of the 1st INBOTS Conference (INBOTS2018), held on October 16-20, 2018 in Pisa, Italy, the book addresses the needs of a broad audience of academics and professionals working in government and industry, as well as end users. In addition to providing readers with detailed information and a source of inspiration for new projects and collaborations, it discusses representative case studies highlighting practical challenges in the implementation of interactive robots in a number of fields, as well as solutions to improve communication between different stakeholders. By merging engineering, medical, ethical and political perspectives, the book offers a multidisciplinary, timely snapshot of interactive robotics.

Covering the full spectrum of rehabilitation after traumatic brain injury, this practical reference by Drs. Blessen C. Eapen and David X. Cifu presents best practices and considerations for numerous patient populations and their unique needs. In an easy-to-read, concise format, it covers the key information you need to guide your treatment plans and help patients relearn critical life skills and regain their independence. Covers neuroimaging, neurosurgical and critical care management, management of associated complications after TBI, pharmacotherapy, pain management, sports concussion, assistive technologies, and preparing patients for community reintegration. Discusses special populations, including pediatric, geriatric, and military and veteran patients. Consolidates today's available information and guidance in this challenging and diverse area into one convenient resource.

This book reviews the latest biotechnological advances with pluripotent stem cells, exploring their application in tissue engineering and medicinal chemistry. Chapters from expert contributors cover topics such as the production of transgene-free induced pluripotent stem cells (iPSCs), expansion, controlled differentiation and programming of pluripotent stem cells, and their genetic instability. Particular attention is given to the application of the pluripotent stem cells for vascularision of engineered tissue and for drug screening. This book will appeal to researchers working in regenerative medicine and drug discovery, and to bioengineers and professionals interested in stem cell research.

This book exclusively focuses on the science and fundamentals of polymer gels, as well as the numerous advantages that polymer gel-based materials offer. It presents a comprehensive collection of chapters on the recent advances and developments in the core science and fundamentals of both synthetic and natural polymer-based gels, and pays particular attention to applications in the various research fields of biomedicine and engineering. Key topics addressed include: polysaccharide-based gels and their fundamentals; stimuli-responsive polymer gels; polymer gels applied to enzyme and cell immobilization; chitosan-based gels for cancer therapy; natural polymeric and gelling agents; radiation dosimetry; polymeric gels as vehicles for enhanced drug delivery across the skin; transport in and through gel; and polymer gel nanocomposites and functional gels. The book's extensive and highly topical coverage will appeal to researchers working in a broad range of fields in industry and academia alike.

Advanced Perioperative Crisis Management is a high-yield, clinically-relevant resource for understanding the epidemiology, pathophysiology, assessment, and management of a wide variety of perioperative emergencies. Three introductory chapters review a critical thinking approach to the unstable or pulseless patient, crisis resource management principles to improve team performance and the importance of cognitive aids in adhering to guidelines during perioperative crises. The remaining sections cover six major areas of patient instability: cardiac, pulmonary, neurologic, metabolic/endocrine, and toxin-related disorders, and shock states, as well as specific emergencies for obstetrical and pediatric patients. Each chapter opens with a clinical case, followed by a discussion of the relevant evidence. Case-based learning discussion questions, which can be used for self-assessment or in the classroom, round out each chapter. Advanced Perioperative Crisis Management is an ideal resource for trainees, clinicians, and nurses who work in the perioperative arena, from the operating room to the postoperative surgical ward.

Soft Computing Based Medical Image Analysis presents the foremost techniques of soft computing in medical image analysis and processing. It includes image enhancement, segmentation, classification-based soft computing, and their application in diagnostic imaging, as well as an extensive background for the development of intelligent systems based on soft computing used in medical image analysis and processing. The book introduces the theory and concepts of digital image analysis and processing based on soft computing with real-world medical imaging applications. Comparative studies for soft computing based medical imaging techniques and traditional approaches in medicine are addressed, providing flexible and sophisticated application-oriented solutions.

PID Control with Intelligent Compensation for Exoskeleton Robots explains how to use neural PD and PID controls to reduce integration gain, and provides explicit conditions on how to select linear PID gains using proof of semi-global asymptotic stability and local asymptotic stability with a velocity observer. These conditions are applied in both task and joint spaces, with PID controllers compensated by neural networks. This is a great resource on how to combine traditional PD/PID control techniques with intelligent control. Dr. Wen Yu presents several leading-edge methods for designing neural and fuzzy compensators with high-gain velocity observers for PD control using Lyapunov stability. Proportional-integral-derivative (PID) control is widely used in biomedical and industrial robot manipulators. An integrator in a PID controller reduces the bandwidth of the closed-loop system, leads to less-effective transient performance and may even destroy stability. Many robotic manipulators use proportional-derivative (PD) control with gravity and friction compensations, but improved gravity and friction models are needed. The introduction of intelligent control in these systems has dramatically changed the face of biomedical and industrial control engineering.

Aimed at students, researchers, nutritionists, and developers in food technology, this research text addresses the nascent field of metabiotics. Metabiotics are products based on components of cells, metabolites, and signaling molecules released by probiotic strains, engineered to optimize host-specific physiological functions in a way that traditional probiotics cannot. This book examines the history, processes, design, classifications, and functions of metabiotics. It includes an overview of the composition and function of the gut microbiota, and discusses development of target-specific metabiotics. Further coverage includes comparisons to traditional probiotics, as well as probiotic safety and side-effects. Metabiotics: Present State, Challenges and Perspectives provides a complete history and understanding of this new field, the next phase of the probiotic industry.

The Intersection: Where Evidence Based Nursing and Information Literacy Meet describes how the Association of College and Research Libraries (ACRL) Framework and Information literacy Competency Standards for Nursing mesh with nursing essentials, thus speaking to the information needs of nurses, nurse educators, and librarians who support worldwide nursing programs. In order to find the best evidence from studies, students and practicing nurses must be proficient in the entire range of information literacy skills. Though the references for this document are from U.S. organizations, they are applicable to nursing audiences across the globe.

This issue of Physical Medicine and Rehabilitation Clinics will cover a number of important topics related to Interventional Spine Procedures. The issue is under the editorial direction of Dr. Carlos Rivera of the Campbell Clinic. Topics in this issue will include: Cervical epidural steroid injections evidence and techniques; Clinical aspects of transitional lumbosacral segments; Ultrasound use for lumbar spinal procedures; Interventions for the Sacroiliac joint; Peripheral nerve radio frequency; Lumbar epidural steroid injections evidence and techniques; Ultrasound for Cervical spine procedures; Prolotherapy for the thoracolumbar myofascial system; and Radiofrequency Denervation, among others.

This book addresses the fundamental challenges underlying bioelectronics and tissue interface for clinical investigation. Appropriate for biomedical engineers and researchers, the authors cover topics ranging from retinal implants to restore vision, implantable circuits for neural implants, and intravascular electrochemical impedance to detect unstable plaques. In addition to these chapters, the authors also document the approaches and issues of multi-scale physiological assessment and monitoring in both humans and animal models for health monitoring and biological investigations; novel biomaterials such as conductive and biodegradable polymers to be used in biomedical devices; and the optimization of wireless power transfer via inductive coupling for batteryless and wireless implantable medical devices. In addition to engineers and researchers, this book is also an ideal supplementary or reference book for a number of courses in biomedical engineering programs, such as bioinstrumentation, MEMS/BioMEMS, bioelectronics and sensors, and more. Analyzes and discusses the electrode-tissue interfaces for optimization of biomedical devices. Introduces novel biomaterials to be used in next-generation biomedical devices. Discusses high-frequency transducers for biomedical applications.

Aquick reference to clinical information needed in Pediatric Intensive Care Units. The Manual makes extensive use of illustrations tables and boxes and provides up-to-date information on nursing interventions for the critically ill child. It also includes content on psychosocial issues, family needs and PICU instrumentation. Authored by an international expert in pediatric critical care who has incorporated the most up to-date policies, practices, and procedures into the text. Provides manageable summaries so that clinical information needed in PICU's can be quickly referenced. Contains more than 300 illustrations, tables, and boxes to aid in quick referencing of essential critical care information. Provides anatomy and physiology reviews to ensure complete understanding. Contains up-to-date information on nursing interventions that aids in the formulation of appropriate policy and accurate decision-making. Has many updated drug tables for the most current pharmacotherapy interventions. Includes content on psychosocial issues, family needs, and PICU instrumentation to prepare the nurse for the realities of working in a pediatric critical care unit. Features a chapter on burns to assist the pediatric critical care nurse in the care of a child with severe burns. Suggested resource lists provide a practical reference supplement for more detailed conditions.

This proceedings book presents papers from the 10th Cambridge Workshops on Universal Access and Assistive Technology. The CWUAAT series of workshops have celebrated a long history of interdisciplinarity, including design disciplines, computer scientists, engineers, architects, ergonomists, ethnographers, ethicists, policymakers, practitioners, and user communities. This reflects the wider increasing realisation over the long duration of the series that design for inclusion is not limited to technology, engineering disciplines, and computer science but instead requires an interdisciplinary approach. The key to this is providing a platform upon which the different disciplines can engage and see each other's antecedents, methods, and point of view. This proceedings book of the 10th CWUAAT conference presents papers in a variety of topics including Reconciling usability, accessibility, and inclusive design; Designing inclusive assistive and rehabilitation systems; Designing cognitive interaction with emerging technologies; Designing inclusive architecture; Data mining and visualising inclusion; Legislation, standards, and policy in inclusive design; Situational inclusive interfaces; and The historical perspective: 20 years of CWUAAT. CWUAAT has always aimed to be inclusive in the fields that it invites to the workshop. We must include social science, psychologies, anthropologies, economists, politics, governance, and business. This requirement is now energised by imminent new challenges arising from techno-social change. In particular, artificial intelligence, wireless technologies, and the Internet of Things generate a pressing need for more socially integrated projects with operational consequences on individuals in the built environment and at all levels of design and society. Business cases and urgent environmental issues such as sustainability and transportation should now be a focus point for inclusion in an increasingly challenging world. This proceedings book continues the goal of designing for inclusion, as set out by the CWUAAT when it first started.

This book presents the applications of ion-exchange materials in the biomedical industries. It includes topics related to the application of ion exchange chromatography in determination, extraction and separation of various compounds such as amino acids, morphine, antibiotics, nucleotides, penicillin and many more. This title is a highly valuable source of knowledge on ion-exchange materials and their applications suitable for postgraduate students and researchers but also to industrial R&D specialists in chemistry, chemical, and biochemical technology. Additionally, this book will provide an in-depth knowledge of ion-exchange column and operations suitable for engineers and industrialists.

This book highlights the current state of the art in single cell analysis, an area that involves many fields of science - from clinical hematology, functional analysis and drug screening, to platelet and microparticle analysis, marine biology and fundamental cancer research. This book brings together an eclectic group of current applications, all of which have a significant impact on our current state of knowledge. The authors of these chapters are all pioneering researchers in the field of single cell analysis. The book will not only appeal to those readers more focused on clinical applications, but also those interested in highly technical aspects of the technologies. All of the technologies identified utilize unique applications of photon detection systems.