Cancer Therapy and Diagnosis, Part A, Volume 43 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on Mesoporous silica nanoparticle synthesis, Periodic mesoporous organosilica, Nanovalves and other nanomachine-equipped nanoparticles and controlled release, Two-photon light control and photodynamic therapy, Biodegradable PMO nanoparticles, Cationic mesoporous silica and protein delivery, Drug loading, stimuli-responsive delivery and cancer treatment, Animal models and cancer therapy, siRNA delivery and TWIST shutdown for ovarian cancer treatment, and TBC (mesoporous silica nanoparticles and cancer therapy or biodistribution of MSN).

In Collaboration with Consulting Editor, Dr. Jan Foster, Drs. Martin and Badeaux have created an issue where top authors in critical care nursing provide current updates on sepsis care and management. Authors have written clinical reviews on the following topics: International Sepsis Guidelines 2016; Pros and Cons of Early Administration of Intravenous Fluids; PTSD After ICU Stay; Role of Vitamin C and Carbon Monoxide in Sepsis; Neonatal Sepsis; Use of Etomidate in the Septic Patient; Simulation to Manage the Septic Patient in the ICU; Cardiogenic Shock Complicating Sepsis management; Hospital Costs associated with Sepsis Compared to other Medical Conditions; Special Considerations for the Septic Patient Going to the Operating Room; Management of the Septic Patient in the Emergency Room; and Management of Sepsis in the Obstetrical Patient. Reader will come away with the information they need to improve patient outcomes.

Guest edited by Dr. Jeffrey Shook, this issue of Clinics in Podiatric Medicine and Surgery will cover several key areas of interest related to Perioperative Considerations in the Surgical Patient. This issue is one of four selected each year by our series Consulting Editor, Dr. Thomas Chang. Articles in this issue include, but are not limited to: Surgical Consent, Medical Consultation, Prevention of Deep Venous Thromboembolism, Prophylactic Antibiosis, Preoperative Assessment and Perioperative Management of Pulmonary Disease, Preoperative Evaluation of the Pediatric Patient, The Geriatric Patient, Postoperative Convalescence, Perioperative pain management, Preoperative Evaluation and Management of Peripheral Arterial Disease, Preoperative Assessment of the Cardiac Patient, Surgery in the Patient with Renal Disease, and Evaluation and Perioperative Management of the Diabetic Patient.

Get a quick, expert overview of best practices for diagnosis and treatment of eating disorders in children and adolescents. This concise resource by Drs. Johannes Hebebrand and Beate Herpertz-Dahlmann provides psychiatrists and pediatricians with current information in this increasingly important field, including practical sections on developmental aspects of eating disorders, symptomology, epidemiology, etiology and pathyphysiology, treatment and outcomes, and prevention. Discusses general concepts for feeding, eating, and weight disorders; body weight and composition, appetite regulation, and the emergence of body perception and image. Covers genetics of eating and weight disorders, influence of hormones, intergenerational effects, and food addiction. Includes information on cognitive behavioral therapy, family-based therapies, early intervention, pharmacotherapy, bariatric surgery, and other treatments. Consolidates today's available information on this timely topic into a single convenient resource.

In Tom Begert-Clark's book, "Rosie John Doesn't Live Here Any More - One Family's Journey In Eldercare," readers will become companions on the wonderful, heartwarming, emotional and often humorous journey as Tom and his family moved from the role of white collar professional to personal caregiver. These are "stories for the journey" that include practical and emotional tips that will help anyone who must embark on a similar path.

Cervical whiplash injuries continue to be a common problem throughout the industrialized world. Despite recent scientific developments, unhelpful treatment of whiplash injuries such as prolonged immobilization, passive modalities, and unnecessary surgery exist. Many patients with chronic pain are labelled as having "psychological problems." Overtreatment and excessive use of diagnostic imaging are common. Relatively recent developments in this field, backed by extensive study, have initiated an evolution in the treatment of whiplash injury. Dr. Malanga is a well-known expert in the field of physical medicine and rehabilitation, particularly in spinal medicine and orthopedics. The entire book focuses only on whiplash, providing an extremely in-depth treatment. Relatively recent developments in this field, backed by extensive study, have initiated an evolution in the treatment of whiplash injury. Thus, there is a need for a comprehensive presentation of the changed thinking. Includes coverage of the Quebec Whiplash Study.

Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research.

This issue of Physical Medicine and Rehabilitation Clinics, guest edited by Dr. Miriam Segal, will cover the important topic of Muscle Overactivity in Upper Motor Neuron Syndrome, including assessment and problem-solving for complex cases. Topics discussed in the volume will include: Functional/problem based assessment in patients with spinal cord injury; Special considerations in pediatric assessment; Special considerations and assessment of spasticity and multiple sclerosis; Pharmacologic treatment tools; Peripheral neurolysis; The role of physical and occupational therapy; Neurosurgical approaches; The neuro-orthopedic approach; Upper extremity problem-solving: Challenging cases; Lower extremity problem-solving: Challenging cases; and Emerging therapies.

An overview written for general readers of the history, prevention, treatment, causes, and consequences of obesity. What makes obesity a disease instead of just a matter of overeating? What are the genetic and environmental factors behind it? What new breakthroughs are being developing to combat it? This concise, information-rich volume looks at these and other important questions, clearing away misconceptions about this devastating condition. Obesity explains what scientists now know about the causes and consequences of being overweight, including the latest on the links between obesity and heart disease, diabetes, some cancers, asthma, and sleep difficulties. The book pays specific attention to the problem among obese young people, who more and more are being diagnosed with chronic illnesses that used to only be seen in adults. It also reports on promising efforts to battle obesity, from medical treatments to community awareness programs. The work is combines materials from history, epidemiology, behavioral science, surgery, pharmacology, economics, and policy Includes a glossary of key terms related to the study of obesity

Robotic animals are nowadays developed for various types of research, such as bio-inspired robotics, biomimetics and animal behavior studies. More specifically, in the case of collective animal behavior research, the robotic device can interact with animals by generating and exploiting signals relevant for social behavior. Once perceived by the animal society as conspecific, these robots can become powerful tools to study the animal behaviors, as they can at the same time monitor the changes in behavior and influence the collective choices of the animal society. In this book, we present novel robotized tools that can integrate shoals of fish in order to study their collective behaviors. We used the current state of the art on the zebrafish social behavior to define the specifications of the robots, and we performed stimuli analysis to improve their developments. Bio-inspired controllers were designed based on data extracted from experiments with zebrafish for the robots to mimic the zebrafish locomotion underwater. Experiments involving mixed groups of fish and robots qualified the robotic system to be integrated among a zebrafish shoal and to be able to influence the collective decisions of the fish. These results are very promising for the field of animal-robot interaction studies, as we showed the effect of the robots in long-duration experiments and repetitively, with the same order of response from the animals.

Infection Prevention in Surgical Settings is a handbook that provides easy access to guidelines for infection control in various surgical settings. It specifically addresses the needs of nurses practicing in perioperative, PACU, ambulatory surgery, endoscopy, or other surgical settings who need access to current guidelines to meet OSHA and JCAHO requirements. Infection Prevention contains procedure guidelines for preparation of the patient, surgical equipment, personnel, and surgical practices. Each procedure contains a brief description, followed by rationales for the principles outlines in the procedure. Each rationale is referenced to AORN standards, CDC guidelines, and other resources.Provides an easy-to-use reference to common, significant infection control practices & issues found in various surgical and other related settings Brings together the work of recognized experts and professional associations that provide factual, relevant, and succinct rational and correct interpretation of infection control practicesFirst handbook devoted to infection control issues that directly relate to surgical environments Follows a consistent format presentation for each procedure that includes the steps, rationale, references, and suggested additional readings Spanish version also available, ISBN: 84-8174-615-0

Medical breakthroughs and adult literacy have made it easier than ever before to acquire the knowledge, skills, and values needed to lead a productive and satisfying life, yet many Americans have difficulty understanding and acting upon the health information they acquire. The Handbook of Research on Adult and Community Health Education: Tools, Trends, and Methodologies presents educational and social science perspectives on the state of the healthcare industry and the information technologies surrounding it. It presents a collection of the latest research on methods, programs, and procedures practiced by health literate societies. This groundbreaking compilation provides cutting-edge content for researchers, social scientists, academicians, and adult educators and learners interested in how available technologies affect our health today.

This book discusses the methods synthesizing various carbon materials, like graphite, carbon blacks, carbon fibers, carbon nanotubes, and graphene. It also details different functionalization and modification processes used to improve the properties of these materials and composites. From a geometrical-structural point of view, it examines different properties of the composites, such as mechanical, electrical, dielectric, thermal, rheological, morphological, spectroscopic, electronic, optical, and toxic, and describes the effects of carbon types and their geometrical structure on the properties and applications of composites.

Health Data Processing: Systemic Approaches focuses on the design of health information systems and touches on the main themes of medical informatics and public health. The book is written for health professionals in practice or training, and is especially useful for decision-makers or future decision-makers in the field of health information systems. Users will find sections on the question of reusing data for other purposes, protection of individual liberties that this data and technologies make more acute, and the irruption of large masses of genetic data and its related problems. This book develops the methodological and conceptual aspects related to these issues.

Through seven editions, Protocols for High-Risk Pregnancies has helped busy obstetricians keep pace with a constantly evolving field. Providing just-in-time content, its focus on protocols and guidelines helps organize medical thinking, avoid heuristic errors of omission and commission, and optimize maternal and fetal outcomes. As with the prior six editions, the editors have once again assembled some of the world's top obstetrical and medical experts. This seventh edition has also been expanded to include a number of new topics, including: Protocols on opioid use, misuse and addition in pregnancy and postpartum Noninvasive prenatal diagnosis of aneuploidy Periconceptual genetic screening Expanded protocols on maternal valvular heart disease and cardiomyopathies Protocols on arboviruses, including Zika and malaria Protocols for High-Risk Pregnancies: An Evidence-Based Approach will be an essential reference for obstetricians, medical students, general practitioners and all medical professionals who are seeking the most up-to-date information and guidance on high-risk pregnancies.

Integrated Nano-Biomechanics provides an integrated look into the rapidly evolving field of nanobiomechanics. The book demystifies the processes in living organisms at the micro- and nano-scale through mechanics, using theoretical, computational and experimental means. The book develops the concept of integrating different technologies along the hierarchical structure of biological systems and clarifies biomechanical interactions among different levels for the analysis of multi-scale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it is shown how knowledge obtained can be utilized in a range of areas, including diagnosis and treatment of various human diseases and alternative energy production. This book is based on collaboration of researchers from a unique combination of fields, including biomechanics, computational mechanics, GPU application, electron microscopy, biology of motile micro-organisms, entomological mechanics and clinical medicine. The book will be of great interest to scientists and researchers involved in disciplines, such as micro- and nano-engineering, bionanotechnology, biomedical engineering, micro- and nano-scale fluid-mechanics (such as in MEMS devices), nanomedicine and microbiology, as well as industries such as optical devices, computer simulation, plant based energy sources and clinical diagnosis of the gastric diseases.

This issue of Sleep Medicine Clinics focuses on Sleep Disorders in Women's Health, with topics including: Menstrual cycle effects on sleep; Impact of shiftwork on sleep, circadian rhythyms, and health in women; Sleep in pregnancy; RLS in pregnancy; Sleep-disordered breathing in pregnancy; Postpartum sleep and circadian rhythms; Chronic pain and autoimmune disorders in women; Management of sleep disturbance in women with cancer; Impact of stress and trauma on sleep; Sleep disorders in female veterans; Sleep and sleep disorders in the menopausal transition; and Impact of sleep disturbance on health and cognition in elderly women.

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications, Volume One: Types and Triggers discusses, in detail, the recent trends in designing biodegradable and biocompatible single-responsive polymers and nanoparticles for safe drug delivery. Focusing on the most advanced materials and technologies, evaluation methods, and advanced synthesis techniques stimuli-responsive polymers, the book is an essential reference for scientists with an interest in drug delivery vehicles. Sections focus on innovation, development and the increased global demand for biodegradable and biocompatible responsive polymers and nanoparticles for safe drug delivery.

This issue of Heart Failure Clinics--edited by Dr. Eduardo Bossone--will cover The Right Heart Pulmonary Circulation Unit. Topics include Pathophysiology, Increased Systemic versus Increased Pulmonary Pressures, Pulmonary Arterial Hypertension, Right Heart Pulmonary Circulation Unit in Connective Tissue Disease, Right Heart Pulmonary Circulation Unit in Congenital Heart Diseases, Pulmonary Hypertension and Heart Failure, Right Heart Pulmonary Circulation Unit in Cardiomyopathies and Storage Diseases, Pulmonary Hypertension, Right Heart Pulmonary Circulation Unit at High Altitude, Chronic Thromboembolic Pulmonary Hypertension, Combining Invasive and Non-Invasive Evaluation for the Diagnosis of Pulmonary Hypertension, Imaging the Right Heart Pulmonary Circulation Unit: The Role of Ultrasound, Imaging the Right Heart Pulmonary Circulation Unit: The Role of CT and MRI, Biomarkers in Pulmonary Hypertension, Pulmonary Hypertension Related to Diffuse Parenchymal Lung Disease, Chronic Right Heart Failure, Exercise Training and Rehabilitation in Pulmonary Hypertension, and Right Heart Circulation Unit and Left Heart Valvular Diseases.