Electrospinning, an electro-hydrodynamic process, is a versatile and promising platform technology for the production of nanofibrous materials for tissue engineering and biomedical applications. Electrospun Materials for Tissue Engineering and Biomedical Applications, examines the rapid development of electrospun materials for use in tissue engineering and biomedical applications. With a strong focus on fundamental materials science and engineering, this book also looks at successful technology transfers to the biomedical industry, highlighting biomedical products already on the market as well as the requirements to successfully commercialize electrospun materials for potential use in tissue engineering and biomedical areas. This book is a valuable resource for materials and biomedical scientists and engineers wishing to broaden their knowledge on the tissue engineering and biomedical applications of electrospun fibrous materials.

The nurse-client relationship is at the core of quality nursing care. Nurse coaching is a structured, relationship-centered approach that promotes achievement of client goals. This new edition of The Art and Science of Nurse Coaching: The Provider's Guide to Coaching Scope and Competencies teaches RNs how to interact with clients in a skilled, purposeful, and results-oriented way. Grounded in the principles and core values of professional nursing, these newly updated nurse coaching competencies can be integrated into any setting or specialty area of practice. This book provides strategies to help you: - Create a safe space for coaching conversations. - Provide a structure for further coaching sessions. - Explore client readiness for change. - Assist clients to identify goals, select action steps, evaluate progress, and sustain life changes. - Learn the importance of coaching clients becoming aware of their challenges and celebrating their accomplishments .- Learn new, valuable ways to assist clients to adopt effective, sustainable life-changing behaviours. The Art and Science of Nurse Coaching: The Provider's Guide to Coaching Scope and Competencies, Second Edition is an essential resource for nurses seeking to support clients on their healthcare journey to achieve desired goals for health and healing or transition for peaceful dying.

Sedation is a necessary component of care for critically ill and injured individuals. Sedatives assist in coping with mechanical ventilation and other invasive devices, and help patients tolerate procedures and noxious stimuli in the intensive care unit. Sedatives are also useful in the control of agitation and delirium. In addition to fundamental humane reasons, calming patients with sedatives provides physiologic benefits, such as reducing oxygen consumption expended during restlessness, and prevents dislodgement of life-preserving tubes and catheters. When administering sedatives to manage critically ill patients, clinicians must be cognizant of the many complex issues surrounding their use. This issue, edited by Consulting Editor, Dr. Jan Foster, provides current updates in this area, including new guidelines and a focus on delirium.

This book provides an introduction to the biological background of heart functioning and analyzes the various materials and technologies used for the development of microfluidic systems dedicated to cell culture, with an emphasis on cardiac cells. The authors describe the characterization of microfluidic systems for cardiac cell culture and center their discussion of the use of stem cell stimulation based on four different types: electrical, biochemical, physical, and mechanical. This book is appropriate for researchers focused on on-chip technologies and heart studies, students in bioengineering and microengineering courses, and a variety of professionals, such as biotechnologists, biomedical engineers, and clinicians working in the cardiac diseases field.

Gellan Gum as a Biomedical Polymer details key topics and fundamental aspects of gellan gum and its biomedical applications in drug delivery, proteins and peptides delivery, cell delivery, tissue engineering, wound dressings and enzyme immobilizations in developing high quality products. Sections introduce gellan gum, its source, production and gelation mechanism, discuss biomedical materials, and provides ways it can be used for biomedical applications. The book also examines the used of gellan gum as pharmaceutical excipients for drug delivery. Future developments and challenges round out the book’s coverage. With contributions for an international group of experts, this book is a useful reference for scientists, researchers and those in industry engaged in biomedical product development using natural polysaccharides.

Intended for school psychologists, counselors, and social workers, teachers, and therapists who work with school systems, this book presents a philosophy and numerous practical strategies for handling behavioral problems presented by students.

This book describes the development of three dimensional electroactive fibres using a novel coaxial wet-spinning approach from organic conductors in combination with non-conducting hydrogel polymers. This book also presents the characterization and evaluation of multiaxial biofibres in terms of mechanical, physical, electrochemical and biological properties, and explores their use in a diverse range of applications including implantable electrodes, drug delivery systems and energy-storage systems. In the first chapter, the author highlights the significance of engineering three dimensional fibres, introduces the involved hydrogels and organic conductors with emphasis on their biomedical application, and collects some of the previously established methods for fabrication of biofibres. In the second chapter, particular attention is given to the overall experimental fabrication methods and characterization analyses conducted in the work. Chapters three to five present the main findings of this work, in which readers will discover how novel hybrid hydrogel fibres with an inner core of chitosan and alginate were prepared and characterized, how graphene was incorporated into coaxial wet-spun biofibres, and how one-dimensional triaxial fibres were developed using a novel coaxial wet-spinning fibre production method and applied as potential battery devices. In the final chapter of this work, the author summarizes the main achievements of the work and outlines some recommendations for future research.

This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in diabetes, kidney and wound treatment. All chapters are contributed by pre-eminent scientists in the field and covers such topics as stem cells and cell therapy in the treatment of diabetes mellitus, kidney failure, wound and other skin aging diseases, characteristics of some kinds of stem/progenitor cells for therapy, future directions of the discussed therapies and much more. Pancreas, Kidney and Skin Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

This issue of Clinics in Podiatric Medicine and Surgery will include articles that focus on achilles tendon pathology and will include: Anatomy and Blood supply; Imaging Indications and Techniques; Mid-substance Tendinopathy Background & Clinical Evaluation; Mid-substance Tendinopathy; Non-Surgical Management; Mid-substance Tendinopathy; Percutaneus Techniques; Mid-substance Tendinopathy; Surgical Management; and a plethora of additional articles on this exciting topic.

This book approaches the differential diagnosis and management of rare, hereditary cancer syndromes from a practical angle, addressing the issues pertinent to each tumour type as encountered by health professionals in their day-to-day practice. This book enables readers to correctly identify patients with rare cancer syndromes who would benefit from genetic counselling and testing, and provides the necessary knowledge for appropriate patient management and advising at-risk family members. It begins by describing recent advances in genetic testing for cancer-predisposing genes. Leading experts from Europe and Australia then offer detailed, up-to-date guidance on the diagnosis and management of a wide range of hereditary cancers. The concluding chapter examines the wider issues that are raised by genetic testing for rare cancer syndromes for patients, families and health professionals. This book is an invaluable source of information for all specialists involved in the care of such patients and their families.

A cardiac dysrhythmia is a disturbance in the cardiac rhythm which can be normal (e.g., sinus arrhythmia) or instantly lethal (e.g., sustained ventricular tachycardia). This issue of Critical Care Nursing Clinics of North America will provide state of the art diagnostic and treatment information for cardiac dysrhythmias as well as addressing how to achieve the most accurate diagnostic approach to interpreting an electrocardiogram, which is omnipresent in critical care and of critical importance in diagnosing arrhythmias. Articles in this issue are devoted to: The Normal Cardiac Conduction System; The Normal Electrocardiogram: Resting 12-lead and Continuous Cardiac Rhythm Strips; Premature Beats; Paroxysmal Supraventricular Tachycardia, Including the Special Type Called Wolff-Parkinson-White; Atrial Fibrillation, The Most Common Type of Supraventricular Arrhythmia; Ventricular Tachycardia and Its Disorganized Counterpart, Ventricular Fibrillation; Brady-Dysrhythmias, When Heart Rate Slows Myocardial Ischemia & Infarction and their Relationship to Dysrhythmias; Pharmacologically Induced Dysrhythmias; and Implantable Cardiac Devices and their Role in Dysrhythmias Management.

How do you care for ageing parents without destroying the family emotionally or financially? Author Dan Taylor has answered that question in The Parent Care SolutionT. Dan helps you to initiate the Six Conversations you must have with your parents to plan for their care. Using a unique Conversation Strategy he strips away the reluctance and the awkwardness that often surrounds this topic. Once the Six Conversations are completed he provides effective tools for organizing finances, making gifts, selling the family home, evaluating a care facility and selecting someone for the role of a The Parent Care SpecialistT. Dan has taken all the complexity around this subject and reduced it to a simple confidence producing set of conversations and actions.

This book describes efforts to improve subject-independent automated classification techniques using a better feature extraction method and a more efficient model of classification. It evaluates three popular saliency criteria for feature selection, showing that they share common limitations, including time-consuming and subjective manual de-facto standard practice, and that existing automated efforts have been predominantly used for subject dependent setting. It then proposes a novel approach for anomaly detection, demonstrating its effectiveness and accuracy for automated classification of biomedical data, and arguing its applicability to a wider range of unsupervised machine learning applications in subject-independent settings.

Children have the right to be safe in our world and we all have a responsibility to ensure this happens. Midwives play a key role in enhancing relationships between a child and its parents for future well being. The book explores how the pressures inherent in the transition to parenting, and individual and social circumstances may make it difficult for mothers to respond sensitively to their babies' needs. Midwives are encouraged to use their skills of observation and analysis to recognise and provide appropriate emotional, educational and practical support to assist vulnerable women to bond with their baby and the baby in turn forming a secure attachment with it's mother. Midwives are also in a unique position to recognise potential or actual child abuse and are required to take such action as is necessary to safeguard the child from harm. This book provides midwives with confidence to undertake this role effectively. * Accessible easy to read style for busy working midwives * A sensitive approach to the subject of child protection * Step by step guidance through child protection procedures * Non judgemental approach considering both the needs of the child and the plight of the parent * Case histories link theory to practice

Focussing on the key technologies in developing robots for a wide range of medical rehabilitation activities - which will include robotics basics, modelling and control, biomechanics modelling, rehabilitation strategies, robot assistance, clinical setup/implementation as well as neural and muscular interfaces for rehabilitation robot control - this book is split into two parts; a review of the current state of the art, and recent advances in robotics for medical rehabilitation. Both parts will include five sections for the five key areas in rehabilitation robotics: (i) the upper limb; (ii) lower limb for gait rehabilitation (iii) hand, finger and wrist; (iv) ankle for strains and sprains; and (v) the use of EEG and EMG to create interfaces between the neurological and muscular functions of the patients and the rehabilitation robots. Each chapter provides a description of the design of the device, the control system used, and the implementation and testing to show how it fulfils the needs of that specific area of rehabilitation. The book will detail new devices, some of which have never been published before in any journal or conference.

The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors.

In this book, Spreen and Risser present a comprehensive, critical review of available methods for the assessment of aphasia and related disorders in adults and children. The authors explore test instruments and approaches that have been used traditionally for the diagnosis of aphasia, ranging from bedside screening and ratings, to tests of specific aspects of language, and to comprehensive and psychometrically standardised aphasia batteries. Coverage of other methods reflects newer trends, including the areas of functional communication, testing of bilingual patients, psycholinguistic approaches, and pragmatic and discourse-related aspects of language in everyday life. The authors also examine the expansion of language assessment to individuals with non-aphasic neurological disorders, such as patients with traumatic brain injury, lesions of the right hemisphere, the healthy elderly, and individuals with dementia. Taking a flexible and empirical approach to the assessment process in their own clinical practice, Spreen and Risser review numerous test instruments and their source for professionals and students-in-training to choose from in their own use. The introductory chapters cover the history of aphasia assessment, a basic outline of subtypes of aphasia, both neuro-anatomically and psycholinguistically, and the basic psychometric requirements for assessment instruments. The final part discusses issues in general clinical practice, specifically questions of test selection and interpretation. The book is a thorough and practical resource for speech and language pathologists, neuropsychologists, and their students and trainees.

Almost one out of every three US children is overweight or obese, with minority youth at highest risk. There are limited efficacious pediatric obesity interventions available for clinicians, and successful weight loss trials for minority youth are rare. Even fewer interventions have been shown to significantly improve clinical health outcomes such as adiposity, blood pressure, and cholesterol level, and maintenance of behavior change over the long-term remains a challenge Translation I research in which "bench" findings are applied to the "bedside" is uncommon in the behavioral arena. Thus, advances in our understanding of fundamental human processes such as motivation, emotion, cognition, self-regulation, decision-making, stress, and social networks are not being optimally applied to our most pressing behavioral health problems. This issue of Pediatric Clinics will focus on promising behavioral treatments "in the pipeline" that have been translated from basic behavioral science and are the process of refinement and proof of concept testing.

Pharmacologic options have exploded in recent years, forcing updates and creation of guidelines for their use in a near-simultaneous manner. While some nurses may encounter these new medications at the bedside, drugs with little or no indications in specific arenas may remain unknown to the nurse practicing in a specialized area. This issue of Nursing Clinics of North America offers a broad review of current pharmacologic therapy. Bedside applications (e.g., electronic apps) offering real-time information and updates for clinicians will be highlighted throughout the issue.

Untold stories of people with substance addictions who have recovered without formal treatment Despite the widely accepted view that formal treatment and twelve-step groups are essential for overcoming dependencies on alcohol and drugs, each year large numbers of former addicts quietly recover on their own, without any formal treatment or participation in self-help groups at all. Coming Clean explores the untold stories of untreated addicts who have recovered from a lifestyle of excessive and compulsive substance use without professional assistance. Based on 46 in-depth interviews with formerly addicted individuals, this controversial volume examines their reasons for avoiding treatment, the strategies they employed to break away from their dependencies, the circumstances that facilitated untreated recovery, and the implications of recovery without treatment for treatment professionals as well as for prevention and drug policy. Because of the pervasive belief that addiction is a disease requiring formal intervention, few training programs for physicians, social workers, psychologists, and other health professionals explore the phenomenon of natural recovery from addiction. Coming Clean offers insights for treatment professionals of how recovery without treatment can work and how candidates for this approach can be identified. A detailed appendix outlines specific strategies which will be of interest to addicted individuals themselves who wish to attempt the process of recovery without treatment.

This issue of Sleep Medicine Clinics focuses on Novel Therapies for Sleep-Disorderd Breathing. Article topics include: The problems and pitfalls with current approaches to managing sleep disordered breathing; New approaches to diagnosing sleep disordered breathing; Monitoring progress and adherence with PAP therapy for OSA; The future of dental approaches for the treatment of OSA; Pharmacologic approaches for the treatment of OSA; Novel therapies for the treatment of central sleep apnea; Advances and new approaches to managing sleep disordered breathing related to chronic pulmonary disease; The role of big data in the management of sleep disordered breathing; Using genes and biomarkers to assess risk and identify optimal treatments for patients with sleep disordered breathing, and more!

Biomechanical engineering is involved with creating and producing a variety of products in everyday use, from environmentally safe plastics to various foods, fabrics, and medicines. A combination of engineering and biology, it is a fast-growing field with many new and exciting opportunities in genetic engineering and biotechnology. However, research surrounding biomechanical applications is scattered and often restricted, leading to the need for a comprehensive publication of the recent advances and developments in this emerging field. Design, Development, and Optimization of Bio-Mechatronic Engineering Products provides pivotal research on the application of combining mechanical engineering with human biological systems in order to develop bio-mechatronic products like pacemakers, artificial kidney replacements, artificial hearts, and new joints or limbs to better and more accurately monitor and advance human health. While highlighting topics such as orthotic devices, inter-electrode gap, and biomaterial applications, this publication explores producing artificial material to work in sync with the human body. This book is ideally designed for engineers, health professionals, technology developers, researchers, academicians, and students.