This handbook provides a comprehensive and up-to-date survey of a wide range of developmental and clinical issues in pragmatics. Principally, the contributions to this volume deal with pragmatic competence in a native language, in a second or foreign language, and in a selection of language disorders. The topics which are covered explore questions of production and comprehension on the utterance and discourse level. Topics addressed concern the acquisition and learning, teaching and testing, assessment and treatment of various aspects of pragmatic ability, knowledge and use. These include, for example, the acquisition and development of speech acts, implicatures, irony, story-telling and interactional competence. Phenomena such as pragmatic awareness and pragmatic transfer are also addressed. The disorders considered include clinical conditions pertaining to children and to adults. Specifically, these are, among others, autism spectrum disorders, Down syndrome, and Alzheimer's disease.

This volume of the series Cardiac and Vascular Biology presents the most relevant aspects of vascular mechanobiology along with many more facets of this fascinating, timely and clinically highly relevant field. Mechanotransduction, mechanosensing, fluid shear stress, hameodynamics and cell fate, are just a few topics to name. All important aspects of vascular mechanobiology in health and disease are reviewed by some of the top experts in the field. This volume, together with a second title on cardiac mechanobiology featured in this series, will be of high relevance to scientists and clinical researchers in the area of vascular biology, cardiology and biomedical engineering.

Understanding Pharmacology: Essentials for Medication Safety, 3rd Edition uses a unique combination of simplified language, easy-to-follow headers, and engaging boxes and icons - such as Memory Joggers, Critical Points for Safety, Do Not Confuse, and Drug Alerts - to help you really understand how drugs work, instead of simply memorizing drug information. Updated drug tables with nursing implications ensure you are equipped with all the tools and information you need to safely prepare and administer drugs. Online case studies help you prepare for the Next Generation NCLEX-PN® and NCLEX-RN®. Sections on "Priority Actions to Take Before," "Priority Actions to Take After," and "Teaching Priorities for Patients" emphasize important aspects of drug administration, monitoring, follow-up, and patient teaching. Life span considerations outline nursing implications for drugs used in children, older adults, and pregnant women. Math and dosage calculations review reinforces medication preparation safety. Get Ready for the NCLEX® Examination! sections at the end of each chapter summarize key points and provide review questions that reinforce important concepts learned in the chapter. An array of marginal cartoon icons in Common Side Effects boxes help visual learners remember essential drug side effects. Drug Alert and Do Not Confuse boxes highlight areas of common drug/dosage errors. Memory Jogger boxes help you retain important drug information. Try This! boxes in the math chapter allow you to practice dosage calculation concepts. NEW! Clinical Judgment questions at the end of each clinical chapter offer additional self-assessment on pharmacology and medication administration. NEW! Critical Point for Safety boxes emphasize very important pharmacologic concepts to remember. NEW! Approximately 40 animations on the companion Evolve website supplement important concepts related to understanding pharmacology. NEW! Printed answer key with rationales in the back of the book makes it easy to check your answers and assess your comprehension. UPDATED! Revised drug tables provide adult dosages and nursing implications for individual drugs.

If one tries to imagine the amounts of money that have been spent by federal and state governments, coupled with what has been spent by private citizens in battling substance abuse over the last thirty years, it would amount to an almost unimaginable figure.

There have been many books written that offer criticism regarding the traditional twelve-step treatment approaches to addiction. The problem has been that most of these efforts have failed to offer a viable alternative to traditional treatment. Those that have attempted to do so have merely suggested that singular treatment strategies, such as Cognitive Behavioral Therapy, Psychodynamic Therapy, Gestalt Therapy, etc., should be implemented in conjunction with traditional treatment. "Misunderstanding Addiction" outlines a more holistic treatment method that can be implemented in a variety of environmental contexts that do not require patients to be institutionalized for them to be effective.

"Misunderstanding Addiction" has the potential to radically alter the way that addictions are treated in this country. At a time when healthcare is foremost in the thoughts of our nation's citizens, "Misunderstanding Addiction" offers a timely and important look at how addiction treatment should be undertaken now and in the future to ensure an effective outcome for the patient.

This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students.

This issue of Clinics in Podiatric Medicine and Surgery will take a deep dive into Current Perspectives on Management of Calcaneal Fractures. Guest edited by Dr. Thomas Roukis, Past President of the American College of Foot and Ankle Surgeons, this issue will discuss a number of related topics that are important to practicing podiatrists. This issue is one of four selected each year by our series Consulting Editor, Dr. Thomas Chang. The volume will include: Clinical Management of Acute, Closed Displaced Intra-articular Calcaneal Fractures; Surgical Management of Displaced Intra-articular Calcaneal Fractures; Sinus Tarsi Approach with Screw Fixation or Displaced Intra-articular Calcaneal Fractures; Sinus Tarsi Approach with Subcutaneously Delivered Plate Fixation for Displaced Intraarticular Calcaneal Fractures; Role of Subtalar Arthroscopy with the Sinus Tarsi Approach for Displaced Intra-articular Calcaneal Fractures; Joint Sparing Surgical Management of Sanders IV Displaced Intra-articular Calcaneal Fractures; Intra-operative Reduction Techniques for Surgical Management of Displaced Intra-articular Calcaneal Fractures; Revision Calcaneal Non-union and Secondary Subtalar Arthrodesis with Minimally Invasive Rigid Internal Nail; Fixation for Displaced Intra-articular Calcaneal Fractures; Management of Calcaneal Fracture Malunion with Bone Block Distraction Arthrodesis; Wound Coverage Options for Soft-tissue Defects Following Calcaneal Fracture Management; and Severe Malunion Deformity after Displaced Intra-articular Calcaneal Fractures, among others.

This volume provides a complete update of all the materials in prior volumes on the subject (including current directories to testing labs and other support establishments worldwide), while adding substantial new material on the following topics: * The history of CROs, including snapshots of CROs and a genealogy chart making clear where they came from and where they went. * Study directors and principal investigators. * The nuts and bolts of study performance. * Electronic reporting requirements - SEND and eCTD (required for NDA, BLA, ANDA, and IND submissions). * Consultants and their roles. * An expanded examination of common problems and their solutions. This book boasts complete directories to the global universe of operating labs - where they are, how to contact them, and what they do (including special capabilities). Additionally, checklists for qualifying labs and manufacturing facilities - and for auditing studies and projects at such facilities - are included. It is directed at those in industry (specifically directed at those working for companies using CRO services) but will also be of interest to scientists or administrators working in research organizations themselves. In this case, the contents of this new work are essential to the target reader because the work, regulations, and actors (CROs) have evolved and changed at a rapid pace in the 10 years since the earlier volume that the author published. Likewise, the companies using these services have come to all be almost completely dependent on outsourcing. The earlier texts remain the only source of their kind (paper or electronic) on the field and the only noncommercial guide to the global industry and this volume provides a complete update.

This issue of Psychiatric Clinics, guest edited by Drs. Harry Brandt and Steven Crawford, is the first of two issues dedicated to a comprehensive review of the latest in Eating Disorder diagnosis and treatment. Under the guidance of series consulting editor Dr. Harsh Trivedi, Drs. Brandt and Crawford will cover a number of essential topics, included, but not limited to: Diagnostic categories and criteria and future considerations, Recent Research on Anorexia Nervosa, Recent Research on Bulimia Nervosa, Recent Research on Binge Eating Disorder, ARFID, Psychological Attributes of Eating Disorders, Genetics of Eating Disorders, The Microbiome and Eating Disorders, Sociocultural influences and eating disorders, Eating Disorders Associated with Bariatric Surgery, Body Image, and Children and Eating Disorders, among others.

This edited volume presents fundamentals as well as applications of oculomotor methods in industrial and clinical settings. The topical spectrum covers 1.) basics and background material, 2.) methods such as recording techniques, markov models, Levy flights, pupillometry and many more, as well as 3.) a broad range of applications in clinical and industrial settings. The target audience primarily comprises research experts and practitioners, but the book may also be beneficial for graduate students.

This book covers several areas, such as immunology, infectious diseases, physiology, general nursing, and medicine as well as measurement accuracy and the history of our understanding of fever. This book employs an interdisciplinary approach to exploring our concept of body temperature and specifically fever. The present volume revolves around thermometry, taking the reader on a journey from the past to the present. Yet while the emphasis is on the clinical importance of obtaining accurate, quantitative measurements of body temperature, the reader is also introduced to the most recent clinical work on the subject. This book represents a truly cross-disciplinary collaboration, using evidence-based practice to integrate physiological and immunological knowledge. The authors' intention with this volume is to help readers gain better insight into the importance of using knowledge from different disciplines to develop an appreciation of the different aspects of body temperature. In addition, the reader will come to understand the concept of fever in a broader perspective than is traditionally adopted.

Compassion and caring are at the very heart of nursing - possibly that's why you were attracted to the nursing profession in the first place. But what does compassionate caring really mean in nursing practice? Compassion, Caring and Communication: Skills for Nursing Practice is a practical book that guides you through the complex dimensions of caring. It considers the ways in which you connect with patients, families and co-workers, and the long-lasting impact of emotions and feelings. Using real-life narratives, case studies and reflection activities, the authors demonstrate how you can develop and maintain the empathy and communication skills you need to create effective, compassionate and caring partnerships. New to the second edition: Comprehensively updated throughout to reflect and highlight current professional pressures and public concerns around nursing practice. Includes a broader range of relevant case studies, discussions and scenarios to engage students and qualified nurses at all levels. Contains new content about the impacts of recent government reports and policies on nursing care, developing an awareness of contemporary issues and debates. The BOND caring framework has been revised and updated alongside new 'caring indicators', to support the development of compassionate caring skills. All references have been updated using the latest sources and evidence-based studies.

Microencapsulations may be found in a number of fields like medicine, drug delivery, biosensing, agriculture, catalysis, intelligent microstructures and in many consumer goods. This new edition of Microencapsulation revises chapters to address the newest innovations in fields and adds three new chapters on the uses of microencapsulations in medicine, agriculture, and consumer products.

The most popular teaching text on laboratory data for pharmacy students and go-to reference for pharmacists in therapeutic practice. Now in its seventh edition, Basic Skills has been expanded and updated to cover new drugs, research, and therapeutic approaches. Written by 40 established clinicians and pharmacy faculty members and reviewed by additional experts, it is designed to make all information clear and quickly accessible. Minicases provide clinical scenarios for using tests and managing patients, and quickview charts throughout offer clear interpretations of lab results. The indispensable guide to interpreting clinical laboratory data. New to this edition: A new chapter on nutrition support Significant updates to all chapters Expanded chapters on Pharmacogenomics and Cardiology Additional section on Infectious Diseases covering Bacteria, and Fungi, Viruses and Mycobacteria Learning points conclude each chapter and highlight key concepts about the laboratory tests 25 chapters divided into three sections: Basic Concepts and Test Interpretations; System Disorders and Diagnostic Tests; and Tests for Special Populations Complex but critical skills are required for clinical pharmacists to effectively use lab data in screening for or diagnosing diseases and in monitoring the safety and effectiveness of treatment. As the only book of its kind specifically written for pharmacists by pharmacists, Basic Skills makes it easier to make accurate and critical decisions based on laboratory data.

Master the essentials of anatomy and body movement to succeed as a physical therapist assistant! Essentials of Kinesiology for the Physical Therapist Assistant, 4th Edition provides you with a solid background in the structure and function of the musculoskeletal system, with clear explanations of normal movement setting the stage for discussions of abnormal movement patterns and treatment techniques. To clarify kinesiology concepts, full-color illustrations show bones, joints, supporting ligaments, and muscles. Written by experienced physical therapy practitioners Paul Jackson Mansfield and Donald A. Neumann, this concise guide prepares PTAs for success in both the classroom and the clinical setting. And it includes a fully searchable eBook version with each print purchase! More than 600 full-color photos and drawings help you understand key concepts. Expert author team of Paul Jackson Mansfield and Donald Neumann represents a combined 50 years of physical therapy practice and more than 40 years of teaching experience. UNIQUE! Illustrations from Kinesiology of the Musculoskeletal System depict body anatomy and movement. UNIQUE! Atlas-style muscle presentations pair the illustration of a specific muscle or group with the relevant attachments, innervations, and actions. Study questions include 20-30 multiple-choice and true/false practice questions in each chapter, serving as a self-assessment tool for exam preparation. UNIQUE! Goniometry boxes in joint-specific chapters show how the goniometer may be used to measure joint angle or range of motion. Clinical Insight and Consider This boxes link the concepts of kinesiology with their clinical applications in physical therapy. Summary tables and boxes pull content together into a concise, quick-reference format. Learning objectives at the start of each chapter include a chapter outline, outcome objectives, and key terms. NEW! Revised content and updated references provide the current information you need to be an effective clinician. NEW! Discussion of Common Patterns of Joint Restriction is included in each chapter. NEW! eBook version is included with print purchase. The eBook includes video clips, animations, flashcards, and labeling exercises, and allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. NEW! Video clips help you interpret new concepts with visual demonstration.