Heteropolyacids as Highly Efficient and Green Catalysts Applied in Organic Transformations introduces heteropolyacids (HPAs) as promising candidates for use as green catalysts. This book initially presents an overview of chemistry of HPAs, including the history of their discovery and applications, systematic classifications, solubility, coordination and binding chemistry, isomerization, stability, redox activity, acidic properties, basicity, skeleton structure, structure types, self-assemblage, surface area, electrochemical behavior, methods of investigation, and characterization. Other sections present and compare the applications of HPAs as homogeneous and heterogeneous catalysts. The book provides readers with a basic-to-advanced range of knowledge on how useful and green HPAs can be used for use as catalysts in organic transformations and even the synthesis of complex organic molecules.

Advances in Carbohydrate Chemistry and Biochemistry, Volume 79 highlights new advances in the field, with this new volume presenting interesting chapters on a range of topics, including Vinyl Sulfone-Modified Carbohydrates: Michael Acceptors and 2p Partners for the Synthesis of Functionalized Sugars, Enantiomerically Pure Carbocycles and Heterocycles and a Biographical Memoire for Leslie Hough.

Advances in Carbohydrate Chemistry and Biochemistry, Volume 80 highlights new advances in the field, with this new volume presenting interesting chapters on a range of topics, including Vinyl Sulfone-Modified Carbohydrates: Michael Acceptors and 2p Partners for the Synthesis of Functionalized Sugars, Enantiomerically Pure Carbocycles and Heterocycles and a Biographical Memoire for Leslie Hough.

Imidazole-Based Drug Discovery covers all categories of imidazole and its derivatives, synthesis, pharmacological applications and drug-based studies. Imidazole scaffolds act as a channel between organic synthesis and medicinal chemistry and compel researchers to explore new drug candidates. This book provides detailed coverage of several greener synthetic protocols and pharmacological applications of imidazole derivatives that are useful to researchers working on designing more promising clinical lead compounds with this scaffold. It also includes information on past decades of research on the synthesis and biological applications of imidazole derivatives. This is an ideal resource for researchers in organic chemistry both in academic and industrial settings, as well as postgraduates in chemistry and medicinal chemistry.

Ionic liquids in Analytical Chemistry: New Insights and Recent Developments focuses on the use of these materials in the field of chemical analysis, paying attention to different areas such as sample preparation, separation techniques, spectroscopy and electrochemical methods. Chapters describe the structure and properties of new ionic liquids and eutectic solvents that are widely used in analytical chemistry, review ionic liquids in sample preparation, liquid, micellar liquid and gas chromatography, and capillary electrophoresis. Final chapters are devoted to spectroscopic and electrochemical techniques. The whole volume provides a broad overview of recent applications of ionic liquids. The book will serve as a valuable resource to researchers and laboratory technicians working in the field, as well as instructors and students of analytical chemistry.

Advances in Physical Organic Chemistry, Volume 55, presents the latest reviews of recent work in physical organic chemistry. The book provides a valuable source of information that is ideal not only for physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. The book's hallmark is its quantitative, molecular level understanding of phenomena across a diverse range of disciplines.

Progress in Heterocyclic Chemistry, Volume 33 is the latest in this annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year's literature on heterocyclic chemistry and articles on new developing topics of particular interest. Chapters in this new release are written by leading researchers who present a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2020. As with previous volumes in the series, this book will enable academic and industrial chemists and advanced students to keep abreast of developments in heterocyclic chemistry.

Strategies and Tactics in Organic Synthesis, Volume 15, provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project present the excitement of conception, the frustration of failure and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. Readers will be educated, challenged and inspired by these accounts, which portray the idea that triumphs do not come without challenges. This innovative approach also helps illustrate how challenges to further advance the science and art of organic synthesis can be overcome, driving the field forward to meet the demands of society by discovering new reactions, creating new designs and building molecules with atom and step economies that provide functional solutions to create a better world.

Pincer-Metal Complexes: Applications in Catalytic Dehydrogenation Chemistry provides an overview of pincer-metal catalytic systems that transform hydrocarbons and their derivatives from an synthetic and mechanistic point-of-view. This book provides thorough coverage of the operating mechanisms and dehydrogenation catalyst compatibility in both functionalized and unfunctionalized hydrocarbon systems. In addition, it includes success stories of pincer-metal systems, as well as current and future challenges. The book is an ideal reference for researchers practicing synthetic organic chemistry, inorganic chemistry, organometallic chemistry and catalysis in academia and industry. In recent years there has been a surge in the research on hydrocarbon dehydrogenation catalytic systems that are compatible with polar substituents. This helps facilitate formulation of tandem processes that are not limited to hydrocarbon transformation but also to hydrocarbon functionalization in a single pot.

Advances in Inorganic Chemistry, Volume 78 presents timely and informative summaries on current progress in a variety of subject areas. Chapters in this new release include Catching reactive species in manganese oxidation catalysis, Mechanistic Puzzles from Iron(III) TAML Activators Including Substrate Inhibition, Zero-Order and Dual Catalysis, Stepping towards C-circular economy: Integration of solar chemistry and biosystems for efficient CO2 conversion into added value chemicals and fuels, Highlighting recent work on metal-coordinated and metallic nanoparticles as NIR imaging probes for biosensing application in living cells, and more. Users will find this to be a comprehensive overview of recent findings and trends from the last decade that covers various kinds of inorganic topics, from theoretical oriented supramolecular chemistry, to the quest for accurate calculations of spin states in transition metals.

Black Seeds (Nigella sativa) is a comprehensive resource covering all aspects of this medicinal plant, well-known for its positive effects in many human ailments. It has been used to promote health and fight diseases, and has been found to have antioxidant, antihypertensive, anti-diabetic, anti-inflammatory, and analgesic effects. It has also been known to have antimicrobial, anticancer, neuro-protectant, cardio protectant, immunomodulator, hepatic protectant characteristics. Thymoquinone, the active compound of the plant, also exhibits these protective qualities against many disorders. This book summarizes the effect of this plant on all the organ systems of the body. Black Seeds (Nigella sativa) is a comprehensive resource for researchers working in pharmacology, food chemistry and pharmaceutical chemistry, both in industry and academia.

Studies in Natural Products Chemistry, Volume 71 covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, hence users will find the detailed information in this book to be a great resource on the topics covered.

Carbohydrate Analysis by Modern Liquid Phase Separation Techniques, Second Edition, presents readers with the various principles of modern liquid phase separation techniques and their contributions to the analysis of complex carbohydrates and glycoconjugates. In a selection of all-new chapters, this fully updated volume covers each technique in detail. The book aims to help analysts solve any of the many practical problems they may face in tackling the analysis of carbohydrates. In addition, it addresses current difficulties that must be resolved in carbohydrate research, thus inspiring further important technological developments to meet these challenges. This is an essential resource for anyone seeking a broad view of the science of carbohydrates and separation techniques.

Studies in Natural Products Chemistry, Volume 70 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, this book presents exciting opportunities in the field of new drug development to the pharmaceutical industry. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.

Discovery and Development of Anti-Breast Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogs that show promising potential to act as anti-breast cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields. Discovery and Development of Anti-Breast Cancer Agents from Natural Products will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for breast cancer, highlighting a number of key structures from natural products and exploring possible future developments in the area.

Recent Applications of Selected Name Reactions in the Total Synthesis of Alkaloids includes comprehensive coverage of name reactions in the synthesis of alkaloids. This book highlights the synthesis of various alkaloids using special name reactions including the Diels-Alder, Friedel-Crafts, Heck, Mannich, Pauson-Khand, Pictet-Spengler, Sonogashira and Suzuki reactions. In this book, some selected name reactions in the total synthesis of alkaloids are covered, as they can be used as the key step/steps in the synthesis of different alkaloids exhibiting various biological activities. All chapters include an introduction, history and mechanism of the name reaction, and present the origin of the natural product and its known biological activities. The pathway to total synthesis is visually illustrated, and the focus is on the step in which a name reaction is applied. Chemists working in the area of synthetic organic chemistry will find this reference useful, as well as those working to develop novel methodologies for the synthesis of natural products in both academia and industry. This book is also beneficial to biologists, pharmacists and botanists.

Advances in Organometallic Chemistry, Volume 76, the latest release in this longstanding serial is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. It is ideal for a wide range of researchers involved in organometallic chemistry, including synthetic protocols, mechanistic studies and practical applications.

Advances in Heterocyclic Chemistry is the definitive series in the field - one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds.

Progress in Medicinal Chemistry, Volume 60 provides a review of eclectic developments in medicinal chemistry. Each chapter is written by an international board of authors who cover topics including Venoms in Drug Discovery, Designing Protacs as a Drugs, Automated synthesis and enabling tools for Medicinal Chemistry, Use of Molecular Docking Computational Tools in Drug Discovery, and An industrial perspective on co-crystals: screening, identification and development of the less utilized solid form in drug discovery and development.

This title is a Pearson Global Edition. Theeditorial team at Pearson has worked closely with educators around the world toinclude content which is especially relevant to an international and diverseaudience. For coursesin Organic Chemistry (2 Semester) Engagestudents in complex problem solving with unparalleled pedagogy Wade & Simek's OrganicChemistry focuses students on the fundamental reasoning and principlesof organic chemistry without compromising the conceptual underpinnings andclear explanations needed to prevent memorization. The authors' hallmarkstudent-oriented approach to problem-solving directs students to the individualsteps of each reaction, shows how the steps contribute to the overall reaction,and incorporates unique strategies and hints. Organized around functionalgroups, the text incorporates complete discussions of mechanisms. Thetwo-tiered approach to Mechanism and Key Mechanism Boxes concentrates on 20 KeyMechanisms that comprise nearly all of the mechanisms students will encounter. Mastering isthe teaching and learning platform that empowers you to reach every student. Bycombining trusted author content with digital tools developed to engagestudents and emulate the office-hour experience, Mastering personalizeslearning and improves results for each student. Mastering Chemistry provides anextension of learning, allowing students a platform to practice, learn, andapply knowledge outside of the classroom. Plus, givestudents anytime, anywhere access with Pearson eText Pearson eText is asimple-to-use, mobile-optimized, personalized reading experience availablewithin Mastering Chemistry. It lets students highlight, take notes, and reviewkey vocabulary all in one place - even when offline. Seamlessly integratedvideos and other rich media engage students and give them access to the help theyneed, when they need it. Educators can easily share their own notes withstudents so they see the connection between their eText and what they learn inclass.

Studies in Natural Products Chemistry, Volume 69 covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes. With rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up opportunities in drug development.

Catalysis in Biomass Conversion, Volume 77 in the Advances in Inorganic Chemistry series, presents timely and informative summaries on current progress in a variety of subject areas. This acclaimed serial features reviews written by experts in the field, serving as an indispensable reference to advanced researchers that empowers readers to pursue new developments in each field. Users will find this to be a comprehensive overview of recent findings and trends from the last decade that covers various kinds of inorganic topics, from theoretical oriented supramolecular chemistry, to the quest for accurate calculations of spin states in transition metals.

Advances in Organometallic Chemistry, Volume 75, the latest release in this longstanding serial that is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more provides a wide range of information, with this updated release including chapters on Two- and three-coordinate complexes featuring M-C bonds, Polymerization of terpene and terpenoids using well defined organometallic compounds, Bimetallic Frustrated Lewis Pairs, Organometallic based magnetic switches under confinement, Chemical Bonding and Dynamic Magnetism in f-Element Organometallic Sandwich Compounds, Tris-pyridyl Main Group Ligands: Design and Applications, Reactivities of N-heterocyclic carbenes at metal centers, and more.