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Books > Medicine > Other branches of medicine > Pharmacology

Treatment of Non-vitamin K Antagonist Oral Anticoagulants - For Prevention of Stroke (Hardcover, 1st ed. 2017): Masaaki Uno,... Treatment of Non-vitamin K Antagonist Oral Anticoagulants - For Prevention of Stroke (Hardcover, 1st ed. 2017)
Masaaki Uno, Kuniaki Ogasawara
R2,886 Discovery Miles 28 860 Ships in 10 - 15 working days

This book describes new concepts and strategies for the clinical application of non-vitamin K antagonist oral anticoagulants (NOACs) for stroke. Although vitamin K antagonists have traditionally been used for the prevention of stroke, there are some problems associated with their use, such as the risk of intracranial hemorrhage, the need for dietary restrictions, and individual variability. Recently, NOACs have been introduced as alternatives to traditional anticoagulants and are becoming an option for treating stroke patients around the globe. However, their use is not without risk. Each chapter describes the successful use of NOACs for stroke patients and discusses their future impact from various points of view. The book is primarily written for neurosurgeons and neurologists but is also of interest to cardiologists involved in stroke treatment.

Drug Design: Principles and Applications (Hardcover, 1st ed. 2017): Abhinav Grover Drug Design: Principles and Applications (Hardcover, 1st ed. 2017)
Abhinav Grover
R4,372 Discovery Miles 43 720 Ships in 12 - 17 working days

This book offers an in-depth discussion of the latest strategies in the field of drug design and their applications in various disorders, in order to encourage readers to undertake their own projects.It also includes the contemporary application of drug-designing methodologies to inspire others to further expand the utility of this field in other diseases.It is intended for advanced undergraduate and graduate students, postdocs, researchers, lecturers and professors in bioinformatics, computational biology, medicine, pharmaceutics and other related fields.

Project Management for Drug Developers (Hardcover): Joseph P. Stalder Project Management for Drug Developers (Hardcover)
Joseph P. Stalder
R2,331 Discovery Miles 23 310 Ships in 9 - 15 working days

Project managers in drug development are the driving force behind the coordination of efforts. This book provides a practical reference for project managers in the pharmaceutical and biotech drug development industry, with the goal of assisting in creating an efficient and effective team structure and environment. The text details the role of project managers at each stage of drug development, the key interfaces that the PM will need to work closely with, and essential tools of the trade including frequently used techniques and methodologies. This book is useful for both entry-level and advanced-level PMs, as well as non-project managers from other functions. Features Includes authors' recent experience with improved tactics and technologies/software at various stages of drug development. Provides the most up-to-date and best practices, techniques, and methodologies in project management. Details the role of the PM at each stage of drug development, including working with the key interfaces throughout the process. Diverse audience including nonproject managers in clinical development, clinical operations, regulatory affairs, medical affairs, clinical pharmacology, and biostatistics. Provides templates and timelines for critical paths from development to commercialization and has potential as a textbook on relevant courses.

Pharmacology Made Incredibly Easy (Paperback, Fifth, International Edition): Lippincott Williams & Wilkins Pharmacology Made Incredibly Easy (Paperback, Fifth, International Edition)
Lippincott Williams & Wilkins; Edited by Cherie R Rebar, Nicole M Heimgartner, Carolyn J. Gersch
R929 R874 Discovery Miles 8 740 Save R55 (6%) Ships in 12 - 17 working days

Ready to master the medication process? Tap into the go-to resource for nursing pharmacology basics, with the fully updated new fifth edition of Pharmacology Made Incredibly Easy! (R). Offering clear, concise descriptions of crucial nursing pharmacology concepts and procedures, this easy-to-follow, colorfully illustrated guide offers step-by-step guidance so to can grasp the fundamentals in enjoyable Incredibly Easy style. From initial assessment to safe medication administration and patient care plans, this is the perfect supplement to class materials, offering solid preparation for NCLEX (R), as well as a handy refresher for experienced nurses. Learn the ins and outs of nursing pharmacology care, with the latest data and protocols: NEW chapters on patient education, sensory drugs, and dermatologic drugs NEW chapter on medication safety, including abbreviations to avoid and a review of dosage calculations NEW content on current approved medications and dosages, and expected versus adverse effects NEW content on emergency drugs, herbs/supplements, immunization schedule, and more Hundreds of colorful diagrams, drawings, and charts that illustrate core concepts, with easy-to-retain definitions and clear direction on administering drugs; drug distribution, absorption, and metabolism; drug classes and their uses; and potential drug interactions Quick-scan outline format offers up-to-date guidance on areas including: Nursing pharmacology fundamentals Concepts of pharmacokinetics, pharmacodynamics, and pharmacotherapeutics Pain drugs, autonomic nervous system drugs, neurologic and neuromuscular drugs Psychotherapeutic, anti-infective, anti-inflammatory, anti-allergy, and immunosuppressant drugs Antineoplastic drugs, drugs for fluid and electrolyte balance Ways a drug may affect patients of different ages and other warnings Content reflects the NCSBN Clinical Judgment Measurement Model - guidance from initial assessment to evaluating outcomes "Practice Makes Perfect" end-of-book practice exam - approximately 100 new NCLEX (R)-style questions, to increase your exam confidence Chapter features include: Prototype pro - Actions, indications, and nursing considerations for common prototype drugs A three-step process is provided throughout the chapters to help you care for individuals taking commonly prescribed medications Pharm function - Explains and illustrates how drugs act in the body, and addresses how to recognize and treat adverse reactions Before you give that drug - Warnings to consider before you administer a drug Education edge - Information to share with your patient Black Box Warnings boxes draw attention to life-threatening concerns Lifespan Lightbulb boxes highlight information about how a drug or drug class may affect patients of different ages Quick quiz - End-of-chapter questions with answers/explanations, to help you remember the essentials Nurse Joy and Jake illustrated characters offer tips and insights throughout About the Clinical Editors Cherie R. Rebar, PhD, MBA, RN, CNE, CNECI, COI, FAADN, is a Professor of Nursing at Wittenberg University in Springfield, Ohio Nicole Heimgartner, DNP, MSN, RN, CNE, CNECI, COI, is a Nursing Faculty member at Galen College of Nursing in Louisville, Kentucky Carolyn Gersch, PhD, MSN, RN, CNE, is a Professor of Practice in the Nursing Program at Wittenberg University in Springfield, Ohio

Biomarker Discovery in the Developing World: Dissecting the Pipeline for Meeting the Challenges (Hardcover, 1st ed. 2016):... Biomarker Discovery in the Developing World: Dissecting the Pipeline for Meeting the Challenges (Hardcover, 1st ed. 2016)
Sanjeeva Srivastava
R3,786 R3,558 Discovery Miles 35 580 Save R228 (6%) Ships in 12 - 17 working days

This book is oriented towards post-graduates and researchers with interest in proteomics and its applications in clinical biomarker discovery pipeline. Biomarker discovery has long been the research focus of many life scientists globally. However, the pipeline starting from discovery to validation to regulation as a diagnostic or therapeutic molecule follows a complex trajectory. This book aims to provide an in-depth synopsis on each of these developmental phases attendant to biomarker "life cycle" with emphasis on the emerging and significant role of proteomics. The book begins with a perspective on the role of biorepositories and need for biobanking practices in the developing world. The next chapter focuses on disease heterogeneity in context to geographical bias towards susceptibility to the disease and the role of multi-omics techniques to devise disruptive innovations towards biomarker discovery. Chapter 3 focuses on various omics-based platforms that are currently being used for biomarker discovery, their principles and workflow. Mass spectrometry is emerging as a powerful technology for discovery based studies and targeted validation. Chapter 4 aims at providing a glimpse of the basic workflow and considerations in mass spectrometry based studies. Rapid and aptly targeted research funding has often been deemed as one of the decisive factors enabling excellent science and path breaking innovations. With the need for sophistication required in multi-omics research, Chapter 5 focuses on innovative funding strategies such as crowdfunding and Angel philanthropy. Chapter 6 provides the latest advances in education innovation, the premise and reality of bioeconomy especially in a specific context of the developing world, not to mention the new concept of "social innovation" to link biomarkers with socially responsible and sustainable applications. Chapter 7, in ways similar to biomarkers, discusses the biosimilars as a field that has received much focus and prominence recently due to their immense potential in clinical and pharmaceutical innovation literatures. The broader goal post-biomarker discovery is to translate their use in clinics. However, the road from bench-to-bed side is arduous and complex that is subject to oversight from various national and international regulatory bodies. Chapter 8 underscores these regulatory science considerations and provides a concise overview on intellectual property rights in biomarker discovery. Thus, this book contributed by eminent biomarker scientists, clinicians, translational researchers and social scientists holistically covers the various facets of the biomarker discovery journey from "cell to society" in developing world. The lessons learned and highlighted here are of interest to the life sciences community in a global and interdependent world.

Bee Products - Chemical and Biological Properties (Hardcover, 1st ed. 2017): Jose M. Alvarez-Suarez Bee Products - Chemical and Biological Properties (Hardcover, 1st ed. 2017)
Jose M. Alvarez-Suarez
R6,218 Discovery Miles 62 180 Ships in 12 - 17 working days

This book presents an updated discussion of the chemical composition and biological properties of the main bee products. Specific attention is focused on the beneficial biological activities of bee products in human health. Honey, royal jelly, propolis, bee pollen and bee venom are used as nutriment and in traditional medicine. Their composition is rather variable and depends on the floral source and external factors, such as seasonal, environmental conditions and processing. Bee products are rich in several essential nutrients and non essential nutrients, as sugars, minerals, proteins, free amino acids, vitamins, enzymes and polyphenols, that seem to be closely related to their biological functions. The effects of these products in nutrition, aging and age-related diseases, cancer, neurodegenerative diseases and pathogen infections are discussed.

Albumin in Medicine - Pathological and Clinical Applications (Hardcover, 1st ed. 2016): Masaki Otagiri, Victor Tuan Giam Chuang Albumin in Medicine - Pathological and Clinical Applications (Hardcover, 1st ed. 2016)
Masaki Otagiri, Victor Tuan Giam Chuang
R5,681 Discovery Miles 56 810 Ships in 12 - 17 working days

This book presents a comprehensive overview of medical and pharmaceutical applications of human serum albumin (HSA), with updates on structural aspects of albumin from the perspectives of X-ray crystallography and NMR, endogenous and exogenous ligand binding of albumin in various pathological conditions, and genetic variants and their phenotypes. Rapid progress and development of its applications have resulted in outstanding results for which albumin has clearly been proven to be a robust biomaterial. Contributions from leading international experts in this field show how HSA is applied to diagnosis, therapy, drugs, and treatment, with a comprehensive introduction of HSA. This volume will appeal to scientists in pharmaceutical and medical research including pharmaceutical chemists, pharmacokineticists, toxicologists, and biochemists not only in academia but also in industry. Readers can effectively acquire the most recent knowledge of applications of HSA and its impact on human health in a single volume.

Herbal Insecticides, Repellents and Biomedicines: Effectiveness and Commercialization (Hardcover, 1st ed. 2016): Vijay Veer,... Herbal Insecticides, Repellents and Biomedicines: Effectiveness and Commercialization (Hardcover, 1st ed. 2016)
Vijay Veer, Reji Gopalakrishnan
R4,878 R3,821 Discovery Miles 38 210 Save R1,057 (22%) Ships in 12 - 17 working days

This book looks closely at herbal product development and commercialisation. In spite of an ever-growing demand, there is a dearth of safe and effective herbal products that meet consumers' expectations. Therefore, this book takes it upon itself to elaborate on the development process of herbal insecticides, repellents and biomedicines from a commercialisation point of view. The introductory chapters deal with the various strategies for disease vector control and provide an overview of herbal biomedicines. The subsequent chapter describes plants with mosquito larvicidal activity, including a comprehensive list of lethal concentrations against different mosquito species. The chapter on Himalayan plants discusses potential botanical insecticide sources and their chemical constituents before delving into the topic of natural insecticides of microbial origin and their efficacy against mosquitoes. Plant-derived insecticides belonging to different chemical classes and the extraction, purification and characterisation of bioactive compounds are illustrated, as well. The recent technological advances in the formulation of microbial, biochemical and botanical insecticides are also reviewed. Three chapters focus on important medicinal plants useful for treating human ailments, with special reference to the traditional healing practices of northeastern India. This is followed by a chapter on the production, use and safety of biopharmaceuticals and edible, plant-based vaccines. The intellectual property issues related to herbal products in India including patents, trademarks, geographical indications, trade secrets and traditional knowledge resources are plainly examined. The book ends with a chapter on the herbal product registration process in India, wherein the data requirements for registration, clinical efficacy trials, toxicity studies, quality control, packaging and labelling are clearly explained. In conclusion, this book is a step-by-step guide for the development of safe, effective and commercially viable herbal insecticides, repellents and biomedicines.

Venom Genomics and Proteomics (Hardcover, 1st ed. 2016): P. Gopalakrishnakone, Juan J. Calvete Venom Genomics and Proteomics (Hardcover, 1st ed. 2016)
P. Gopalakrishnakone, Juan J. Calvete
R10,175 Discovery Miles 101 750 Ships in 10 - 15 working days

This volume provides the reader with recent advances in the fields of molecular toxinology, the biotechnological applications of venom toxins, and antivenom production. The content of the twenty chapters of Venom Genomics and Proteomics illustrates not only the enormous progress made since the implementation of omics technologies in the field of toxinology, but one also realizes the road still ahead to reach a holistic view of venomous systems. Advancement in high-throughput technologies in the field of venomics has resulted in the ability to generate comprehensive venom profiles for many species. However, research on snake genomes is still in its infancy, although such studies are eagerly awaited to gain insights into the evolutionary history of snake venom proteins, including the mechanisms that originated venom and the regulation of toxin expression. Fortunately, this objective is also at the reach of current omic technologies. Therefore it would not be unrealistic to predict a bright near future to the field of molecular toxinology. Venom Genomics and Proteomics covers research into the venom of scaled reptiles (lizards and snakes), scorpions, spiders, ants and platypuses. Special consideration is given to a number of observations made in the area of snake venom and in the application of advanced genomics and proteomics techniques on a variety of venom samples. The final chapters give some insight into the potential clinical uses of venom derivatives and into the importance and challenges faced in the production and quality control of antivenoms.

Pharmaceutical Pharmacology (Hardcover): S. C. Mehta, Ashutosh Kar Pharmaceutical Pharmacology (Hardcover)
S. C. Mehta, Ashutosh Kar
R2,031 Discovery Miles 20 310 Ships in 12 - 17 working days

"Pharmaceutical Pharmacology", encompassing 78 chapters, is divided into four major comprehensive parts. Part A deals with general pharmacology, pharmacology of peripheral nervous system and pharmacology of central nervous system. Part B is concerned with pharmacology of cardiovascular system, drugs acting on the hemopoetic system, drugs acting on the urinary system, autocoids and drugs acting on the respiratory system. Part C contains chapters on drugs acting on the gastrointestinal tract, pharmacology of endocrine system, chemotherapy and principles of toxicology. Part D discusses mainly clinical pharmacy, pharmacotherapy, important disorders of organ system and their management, therapeutic drug monitoring and concept of essential drugs and rational drug use.To provide a realistic approach to the understanding of the subject, each chapter commences with a crisp introduction followed by classification, treatment of each class of drugs with reference to important 'drugs' vis-a-vis pharmacological actions, pharmacokinetic actions, mechanism of action, therapeutic uses, dosage regimens, adverse drug reactions, drug interaction, etc. The text is profusely illustrated with labelled diagrams, graphics and lucid explanations. It provides the reader an explicit route starting from the molecular understanding of receptors and drug activities to the therapeutic applications of the most important class of drugs.

The Guinea Pig Model - An Alternative Method for Vaccine Potency Testing (Paperback): Viviana Parreño The Guinea Pig Model - An Alternative Method for Vaccine Potency Testing (Paperback)
Viviana Parreño
R1,234 Discovery Miles 12 340 Ships in 9 - 15 working days

This book summarizes the development and statistical validation of a guinea pig model as an alternative for potency testing of the viral antigens included in combined vaccines applied in cattle to control the respiratory, reproductive, and neonatal calf diarrhea syndromes. The model allows, in one serum sample, to test the vaccine quality for all the viral antigens included in aqueous as well as in oil-adjuvanted formulations of bovine vaccines. The methodology proposed for the control of bovine herpes virus, parainfluenza, and rotavirus were recommended by CAMEVET as guidelines for the 30 countries in the forum, including the US. Key Features Reviews combined vaccines used for cattle Summarizes animal models used for vaccine testing Focuses on bovine herpesviruses, rotaviruses, parainfluenza, and bovine viral diarrhea virus Provides guidance on the effectiveness of the Guinea Pig model for testing vaccine immunogenicity

Anesthesia and Neurotoxicity (Hardcover, 1st ed. 2017): Yuji Morimoto Anesthesia and Neurotoxicity (Hardcover, 1st ed. 2017)
Yuji Morimoto
R4,328 R3,514 Discovery Miles 35 140 Save R814 (19%) Ships in 12 - 17 working days

This book, written by leading Japanese experts in the field, describes the latest findings on the neurotoxicity of anesthetics for the developing brain, postoperative delirium and cognitive dysfunction. It describes the risk factors for postoperative cognitive dysfunction in elderly surgical patients. Since the number of elderly patients undergoing surgery and anesthesia continues to increase, it is important to improve our understanding of the risks and mechanisms of postoperative delirium and cognitive dysfunction, potential ways to prevent or alleviate them and the public health implications. Recently, it has been shown that using anesthetics on the developing brain causes apoptotic neurodegeneration and persistent learning/memory deficits later in life. Anesthesiologists need more information on this mechanism in the human brain. The negative effects of anesthesia and surgery on the nervous system have attracted attention lately; this book provides physicians, researchers, and postdocs with invaluable information on this topic.

Drugs During Pregnancy - Methodological Aspects (Hardcover, 1st ed. 2016): Bengt Kallen Drugs During Pregnancy - Methodological Aspects (Hardcover, 1st ed. 2016)
Bengt Kallen
R1,506 Discovery Miles 15 060 Ships in 10 - 15 working days

This book addresses methodological aspects of epidemiological studies on maternal drug use in pregnancy. Discussing the existing sources of error and how they can produce incorrect conclusions, it examines various epidemiological techniques and assesses their strengths and weaknesses. These refer both to the identification of outcomes (with special emphasis on congenital malformations) and to the types of exposure (drug use). Further, the book discusses the problem of confounding and how to handle it, and provides a simple introduction to statistics. Special situations, e.g. different types of parental exposure, are examined. Lastly, the book discusses pharmacovigilance and the information problem, concluding with a short list of aspects to consider when one wants to evaluate a published paper in the field. Though the book is primarily intended for pharmacologists, gynecologists and obstetricians, it will benefit all doctors working in perinatal care.

Glucosinolates (Hardcover, 1st ed. 2017): Jean-Michel Merillon, Kishan Gopal Ramawat Glucosinolates (Hardcover, 1st ed. 2017)
Jean-Michel Merillon, Kishan Gopal Ramawat
R10,015 Discovery Miles 100 150 Ships in 10 - 15 working days

This is the first comprehensive reference compilation on the substance class of glucosinolates. This handbook introduces the reader to the sulfur-containing glucosinolates (S-glucosides), a class of secondary metabolites of almost all plants of the order Capparales, in particular in the family Brassicaceae (e.g. broccoli and other cabbages), derived from glucose and an amino acid. The book illustrates the natural variety of glucosinolate structures, mainly derived from the precursor amino acid. Chapters describe the resulting rich bioactivity of the glucosides, for example as anti-cancer agents, insecticides, nematicides, fungicides, their potential phytotoxic effects, antimicrobial activity and their possible role in neurodegenerative diseases and human health. Different methods for the extraction, characterization, quantification and processing of the glucosinolates are introduced, and potential applications are discussed. The fate of glucosinolates during food processing is also briefly addressed. This handbook is written by leading experts and structured in different sections addressing the natural occurrence of glucosinolates, their (bio-)synthesis, bioactivity, food processing of glucosinolate-containing vegetables, health and disease-related aspects, biotechnology, and methods applied in glucosinolate-research. It is thus a rich reference source for every reader working in the field, from chemists and biotechnologists, to life scientists, pharmacists and medical scientists.

Hepatitis C Virus Treatment - Highly Effective Therapy with Direct Acting Antivirals and Associated Viral Resistance... Hepatitis C Virus Treatment - Highly Effective Therapy with Direct Acting Antivirals and Associated Viral Resistance (Hardcover, 1st ed. 2017)
Kazuaki Chayama
R2,886 Discovery Miles 28 860 Ships in 10 - 15 working days

This book introduces readers to Direct Acting Antiviral (DAAs) agents, newly developed drugs to treat chronic hepatitis C virus infection, which have an excellent anti-viral effect on virus replication. These drugs have been developed to enhance the effect of interferon and ribavirin, as the resistant strains against each drug have been described both in vitro and in vivo and the existences of naturally occurring variants have been reported. However, since the combination of different classes of DAAs is sufficient to completely eradicate the virus without the need for interferon or ribavirin, the current treatment regimen does not include interferon. Ribavirin is used in combination with sofosbuvir, a potent polymerase inhibitor, to enhance its antiviral effects. Hepatitis C Virus Treatment offers readers a comprehensive guide to hepatitis C; describing the resistance profiles against these drugs and shedding light on the difficulties involved in DAA therapy and the direction of future treatments, it will equip doctors to understand the essentials of treating the disease. It also describes in detail new and innovative DAA treatments, the effects of the agents, and the characteristics of resistance, providing cutting-edge information not only for hepatologists, but also for researchers, clinical residents, and medical students.

Phytopharmaceuticals and Herbal Drugs - Prospects and Safety Issues in the Delivery of Natural Products (Paperback): Manju... Phytopharmaceuticals and Herbal Drugs - Prospects and Safety Issues in the Delivery of Natural Products (Paperback)
Manju Rawat Singh, Deependra Singh
R4,087 Discovery Miles 40 870 Ships in 12 - 17 working days

Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products explores the delivery aspects of plant-based drugs, providing insights into formulation constraints associated with plant-based drugs, the development of novel delivery systems based on polymers or lipids, and how combining natural products with technological advancements in drug delivery is making large strides. Some of the best-selling drugs for the treatment of diseases like cancer, ulcers and malaria are either natural products or their derivatives, all of which are covered in this comprehensive resource. This book will be useful to researchers working in plant-derived medicines and the development of their delivery systems, including sections on their derivatives and analogs that represent over 50% of all drugs in clinical use. Active ingredients originated from plant resources generally exhibit compromised desired effects limited by issues such as stability, solubility, molecular size, bioavailability and toxicity.

Antioxidants in Andrology (Hardcover, 1st ed. 2017): Giancarlo Balercia, Loredana Gandini, Andrea Lenzi, Francesco Lombardo Antioxidants in Andrology (Hardcover, 1st ed. 2017)
Giancarlo Balercia, Loredana Gandini, Andrea Lenzi, Francesco Lombardo
R2,609 Discovery Miles 26 090 Ships in 10 - 15 working days

This book focuses on the use of various molecules with antioxidant properties in the treatment of major male genital tract disorders, especially male infertility, erectile dysfunction, and accessory gland infection. The coverage also includes discussion of pathophysiology, the molecular basis of male infertility, and the rationale for use of antioxidants, with particular attention to coenzyme Q10 and carnitine. Oxidative stress occurs when the production of reactive oxygen species, including free radicals, exceeds the body's natural antioxidant defences, leading to cellular damage. Oxidative stress is present in about half of all infertile men, and reactive oxygen species can produce infertility both by damaging the sperm membrane, with consequences for sperm motility, and by altering the sperm DNA. There is consequently a clear rationale for the use of antioxidant treatments within andrology, and various in vitro and in vivo studies have indicated that many antioxidants indeed have beneficial impacts. In providing a detailed and up-to-date overview of the subject, this book will be of interest to both practitioners and researchers in andrology, endocrinology, and urology.

Drug Discovery and Evaluation: Pharmacological Assays (Hardcover, 4th ed. 2016): Franz J. Hock Drug Discovery and Evaluation: Pharmacological Assays (Hardcover, 4th ed. 2016)
Franz J. Hock
R81,755 Discovery Miles 817 550 Ships in 10 - 15 working days

The 4th edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal and immunomodulatory activities. Each of the more than 1,000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described. For this 4th edition, all existing chapters have been revised and completely updated. A large number of assays were added. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis, - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity. New chapters are added such as Auditory Pharmacology, Oncology Activity, Stem Cells, Omics, Personalized Medicine, etc.

The Maudsley Prescribing Guidelines in Psychiatry,  14th Edition (Paperback, 14th Edition): D Taylor The Maudsley Prescribing Guidelines in Psychiatry, 14th Edition (Paperback, 14th Edition)
D Taylor
R1,787 Discovery Miles 17 870 Ships in 12 - 17 working days

The Maudsley(R) Prescribing Guidelines in Psychiatry The new edition of the world-renowned reference guide on the use of medications for patients presenting with mental health problems The Maudsley Prescribing Guidelines in Psychiatry is the essential evidence-based handbook on the safe and effective prescribing of psychotropic agents. Covering both common and complex prescribing situations encountered in day-to-day clinical practice, this comprehensive resource provides expert guidance on drug choice, minimum and maximum doses, adverse effects, switching medications, prescribing for special patient groups, and more. Each clear and concise chapter includes an up-to-date reference list providing easy access to the evidence on which the guidance is based. The fourteenth edition has been fully updated to incorporate the latest available research, the most recent psychotropic drug introductions, and all psychotropic drugs currently used in the UK, USA, Canada, Australia, New Zealand, and Japan. Several new sections cover topics such as deprescribing of major psychiatric drugs, prescribing psychotropics at the end of life, the treatment of agitated delirium, the genetics of clozapine prescribing, the use of weekly penfluridol, and the treatment of psychotropic withdrawal. Featuring contributions by an experienced team of psychiatrists and specialist pharmacists, the new edition of The Maudsley Prescribing Guidelines in Psychiatry Provides succinct coverage of drug treatment of psychiatric conditions and formulating prescribing policy in mental health Covers a wide range of psychiatric conditions including schizophrenia, bipolar disorder, depression and anxiety, borderline personality, eating disorders, and many others Provides advice on prescribing for children and adolescents, older people, pregnant women, and other special patient groups Offers new sections on genetic prescribing, long-acting injectable formulations, ketamine administration and uses, and dopamine super-sensitivity Includes referenced information on off-label prescribing, potential interactions with other substances such as alcohol, tobacco, and caffeine, and treating patients with comorbid physical conditions Whether in the doctor's office, in the clinic, or on the ward, The Maudsley Prescribing Guidelines in Psychiatry, Fourteenth Edition is a must-have for psychiatrists, pharmacists, neuropharmacologists, clinical psychologists, nurses, and other healthcare professionals working in mental health, as well as trainees and students in medicine, pharmacy, and nursing.

For Blood and Money - Billionaires, Biotech, and the Quest for a Blockbuster Drug (Hardcover): Nathan Vardi For Blood and Money - Billionaires, Biotech, and the Quest for a Blockbuster Drug (Hardcover)
Nathan Vardi
R789 R637 Discovery Miles 6 370 Save R152 (19%) Ships in 10 - 15 working days

For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug, and how the core team-denied their share of the profits-went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time. In the multibillion-dollar business of biotech, where pharmaceutical companies, the government, hedge funds, and venture capitalists have spent billions on funding, experimentation, and treatments, a single molecule can stop cancer in its tracks-and make the people who find that rare molecule astonishingly rich. For Blood and Money follows a small team at a biotech start-up in California, who have found one of these rare molecules. Their compound, known as a BTK inhibitor, seems to work on a vicious type of leukemia. When patients start rising from their hospice beds, the team knows they're onto something big. What follows is a story of genius, pathos, and drama, in which vivid characters navigate a world of corporate intrigue and ambiguous morality. Vardi's narrative immerses readers in the recent explosion of biotech start-ups. He describes the scientists, doctors, and investors who are risking everything to develop new, life-saving treatments, and introduces suffering patients for whom the stakes are life-or-death. A gripping nonfiction read, For Blood and Money illustrates why it's so hard to bring new drugs to market, explains why they are so expensive, and examines how profit-driven venture capitalists are shaping the future of medicine.

Transfusion Science, second edition (Paperback, 2nd Revised edition): Joyce Overfield, Maureen M. Dawson, David Hamer Transfusion Science, second edition (Paperback, 2nd Revised edition)
Joyce Overfield, Maureen M. Dawson, David Hamer
R764 R712 Discovery Miles 7 120 Save R52 (7%) Ships in 12 - 17 working days

There have been a number of significant changes in transfusion science in the last five to ten years and this second edition of Transfusion Science covers these in some detail. * A new chapter introduces readers to the current applications of emerging techniques in transfusion science. * Platelet immune disorders and haemolytic anaemias are now covered. * The need for leucodepletion and methods for pathogen reduction are described. * The latest nomenclature for blood group genes has been adopted. * Current practice in blood group serology is reviewed. * Recent legislative changes for quality assurance in transfusion in the UK are now also covered. Case studies and colour photographs are now provided to illustrate concepts and to aid understanding, and a revised series of self-assessment questions and learning outcomes are also provided. An understanding of transfusion science is vital for all biomedical science students. Transfusion Science, second edition, explains all the basic principles alongside descriptions of the applications now possible as a result of modern analytical techniques. This book is essential reading for all students studying courses on transfusion and transplantation.

Handbook of Arsenic Toxicology (Hardcover, 2nd edition): Swaran Jeet Singh Flora Handbook of Arsenic Toxicology (Hardcover, 2nd edition)
Swaran Jeet Singh Flora
R4,496 Discovery Miles 44 960 Ships in 12 - 17 working days

Handbook of Arsenic Toxicology, Second Edition presents the latest findings on arsenic, including its chemistry, sources and effects on the environment and human health. The book discusses both acute and chronic effects, discussing many aspects of arsenic, from physical and chemical properties, exposure, epidemiology, organ toxicity, diagnosis, prevention and treatment. Fully updated and revised, this new edition includes new topics on risk assessment, molecular mechanisms of arsenic, advances in the integrated approach to testing, assessment and development, evaluation and application of high content predictive models, and new alternative methods (NAMS) in the context of Adverse Outcome Pathways (AOPs) to assess toxicology. This comprehensive resource allows readers to effectively assess the risks related to arsenic, providing them with all they need to know on arsenic exposure, toxicity and toxicity prevention.

A Guide to Online Pharmacy Education - Teaching Strategies and Assessment Methods (Hardcover): Yaser Al-Worafi A Guide to Online Pharmacy Education - Teaching Strategies and Assessment Methods (Hardcover)
Yaser Al-Worafi
R4,440 Discovery Miles 44 400 Ships in 9 - 15 working days

This book describes in detail the various teaching strategies and assessment methods used in pharmacy education. Included in the text is both the advantages and disadvantages of each teaching and assessment method, as well as tips for effective implementation of the strategies. The text covers a plethora of teaching styles, from web based and online learning to lecture and team-based learning, and highlights some of the best practices used worldwide. This book aims to be a valuable single resource for pharmacy educators, students, and researchers. Key features One resource for the pharmacy educators, students, partitioners, researchers, policy makers and other readers with the necessary information and practical guidelines about the online pharmacy education, practice, and research. Describe and discuss the situation of the online pharmacy education, practice, and research around the world. Describe the challenges facing the online pharmacy education, practice, and research and suggest recommendations to overcome the challenges. Describe the pharmacy education teaching strategies and assessment methods. Describe the advantages and disadvantages of each teaching strategy and assessment method. Provide tips for the effective implementation of teaching strategies and assessment methods based on the best practices worldwide.

A Guide to Online Pharmacy Education - Teaching Strategies and Assessment Methods (Paperback): Yaser Al-Worafi A Guide to Online Pharmacy Education - Teaching Strategies and Assessment Methods (Paperback)
Yaser Al-Worafi
R1,840 Discovery Miles 18 400 Ships in 9 - 15 working days

This book describes in detail the various teaching strategies and assessment methods used in pharmacy education. Included in the text is both the advantages and disadvantages of each teaching and assessment method, as well as tips for effective implementation of the strategies. The text covers a plethora of teaching styles, from web based and online learning to lecture and team-based learning, and highlights some of the best practices used worldwide. This book aims to be a valuable single resource for pharmacy educators, students, and researchers. Key features One resource for the pharmacy educators, students, partitioners, researchers, policy makers and other readers with the necessary information and practical guidelines about the online pharmacy education, practice, and research. Describe and discuss the situation of the online pharmacy education, practice, and research around the world. Describe the challenges facing the online pharmacy education, practice, and research and suggest recommendations to overcome the challenges. Describe the pharmacy education teaching strategies and assessment methods. Describe the advantages and disadvantages of each teaching strategy and assessment method. Provide tips for the effective implementation of teaching strategies and assessment methods based on the best practices worldwide.

Advanced Nanoformulations - Theranostic Nanosystems, Volume 3 (Paperback): Md Saquib Hasnain, Amit Kumar Nayak, Tejraj M.... Advanced Nanoformulations - Theranostic Nanosystems, Volume 3 (Paperback)
Md Saquib Hasnain, Amit Kumar Nayak, Tejraj M. Aminabhavi
R4,108 Discovery Miles 41 080 Ships in 12 - 17 working days

Advanced Nanoformulations: Theranostic Nanosystems, Volume Three examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications.

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