Now in its revised and expanded second edition - including over 20 new chapters - this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and systems, respectively. The sections that follow provide detailed descriptions of IVF techniques, embryo culture methods, sperm processing and selection, insemination procedures, micromanipulation, embryo evaluation, cryopreservation, and embryo transfer. Concluding sections address issues of management and regulation of ART labs across the globe, as well as special topics and emerging techniques and devices. Chapter authors, all experts in the field, contribute their expertise from around the world. With the addition of learning key points and review questions at the beginning and end of each chapter, this new edition of In Vitro Fertilization is a readily accessible, high quality instructional resource for reproductive medicine trainees at all levels. Practicing reproductive endocrinologists, urologists, and embryologists also will find value in the book, as will infertility researchers.

It is estimated that more than 4.5 million couples experience infertility each year, and more than 4 million babies have been born using IVF since 1978. However, assisted reproductive technologies continue to raise many medical, social, ethical, political and religious questions, often leading to controversial and sometimes inaccurate opinions about the outcomes of pregnancies resulting from these techniques. This is the first book dedicated to pregnancies arising from assisted reproductive technologies (ART). Chapters cover the most important management issues, from early pregnancy to outcome of children resulting from ART, including gynaecological, genetic and obstetric complications. Each chapter is written and edited by leading experts in the field of human reproduction. A timely, practical and evidence-based guide to the management of ART pregnancies, based on 30 years of clinical experience, this is essential reading for reproductive and maternal-fetal specialists as well as general obstetricians and gynaecologists.

Reproductive donation is the most contentious area of assisted reproduction. Even within Europe there are wide variations in what is permitted in each country. This multi-disciplinary book takes a fresh look at the practices of egg, sperm and embryo donation and surrogacy, bringing together ethical analysis and empirical research. New evidence is offered on aspects of assisted reproduction and the families these create, including non-traditional types. One of the key issues addressed is should children be told of their donor origin? If they do learn the identity of their donor, what kinds of relationships may be forged between families, the donor and other donor sibling families? Should donation involve a gift relationship? Is intra-familial donation too close for comfort? How should we understand the growing trend for 'reproductive tourism'? This lively and informed discussion offers new insights into reproductive donation and the resulting donor families.

If you need help having a baby, reproductive technology can supply the answer. But it also raises a host of questions that won't arise until after the child is born: What will you say to "Where did I come from?" when the answer includes a donor or surrogate? Will knowing the truth about how you conceived make your child love you less? Will having a baby with someone else strain your relationship with your spouse or partner? What will grandparents, family members, friends, and coworkers think? Dr. Diane Ehrensaft--a developmental and clinical psychologist who's worked with families formed using assisted reproductive technology for more than 20 years--helps you anticipate the big questions and find solutions that are right for you and your loved ones. Dr. Ehrensaft offers information, support, and straightforward advice for coping with private worries, confronting public prejudices, and raising happy, healthy children. Single or married, straight or gay, anyone looking forward to the joys and challenges of building a family with the help of a donor or surrogate will discover a wealth of thought-provoking ideas and fresh insights in this sensitive, practical, and positive book.

Modelled after the current MRCOG curriculum, the new edition of this bestselling book provides all the information a specialist registrar in obstetrics and gynaecology or senior house officer needs during training or when preparing for the MRCOG examination. Obstetrics & Gynaecology: An Evidence-based Text for MRCOG covers the latest professional guidelines and developments in obstetrics and gynaecology and continues to provide an easily accessible source of information for those practising as specialists. The book's subsections within obstetrics and gynaecology are divided in line with the RCOG trainee logbook. The text is consistently structured throughout to ensure ease of reference with standardized headings including definitions, incidence, aetiology, investigations and management. Focusing on standards and an evidence-based approach, each chapter includes material on MRCOG standards in an easy-to-consult format. Information on evidence-based medicine is also included to provide a rapid summary of the evidence relating to the interventions and treatments discussed. This text will continue to be an invaluable companion to the higher training of obstetricians and gynaecologists and a useful ready reference for those in established practice.

This book brings together the most up-to-date information about the physiology of progestogens. This volume addresses the bidirectional communication between hormones, fertility, tumors, and autoimmunity. It provides the basic science and clinical perspectives of progestogens which have not been previously available in one volume. In addition to estrogens, androgens, mineralocorticoids and glucocorticoids, progestogens are a major class of steroid hormone. While present in certain phases of estrous and menstrual cycles, progestogens are named for their function in maintaining pregnancy. This book is essentially practical in orientation, addressing the specific issues that confront the practitioner, and provides information to Obstetricians, Gynecologists, Reproductive endocrinologists, as well as Gynecological Oncologists and Rheumatologists. Contributions are from an international team of experts in the field.

The annotated bibliography that follows summarizes some of the more important studies that have been published concerning smoking and its effects on the fetus along with reports of the various efforts that have been undertaken to reduce the impact of smoking during pregnancy. The material has been divided into topics to guide the reader and cross-references are included at the end of each section. An Author Index is also included to guide the reader to relevant publications when only an author's name is known. The following comments constitute an overall summary of the literature.

This book combines the most recent knowledge on the maternal, i.e. oocyte/egg-specific, molecules and processes. The volume covers the most recent advances in a plethora of subjects such as: maternal transfer of immunity, localized RNAs functions and mechanisms of RNA localization, transcriptional repression of maternal messages, maternal inheritance and maternal role of CRISPR/Cas9-based genome editing, chromatin remodeling and epigenetic modifications, maternal function of nucleosomes, maternal mitochondria and energy supply, role of bacterial symbionts and their maternal transmission, acquisition of oocyte polarity and evolution of maternal effect genes, germ plasm and oosome origin and functions, mechanisms of oocyte activation and soma germ cells communication. Currently, no other book on the market combines such a comprehensive list of subjects in one volume. Moreover, the information provided is a cross-section through oocytes from various invertebrate and vertebrate species, which is another unique feature of this book. The readers, therefore, get a completely new and invaluable perspective on all covered subjects.

En el documento Criterios medicos de elegibilidad para el uso de anticonceptivos se revisan los criterios medicos de elegibilidad para el uso de anticonceptivos y se ofrece orientacion sobre la seguridad de la utilizacion de diferentes metodos para mujeres y hombres con condiciones medicas conocidas o caracteristicas especificas. Las recomendaciones estan basadas en revisiones sistematicas de investigaciones clinicas y epidemiologicas disponibles. Es una guia complementaria de las Recomendaciones sobre practicas seleccionadas para el uso de anticonceptivos. Juntos, estos documentos estan destinados a responsables de la formulacion de politicas, directores de programas y la comunidad cientifica, con el fin de apoyar a los programas nacionales en la preparacion de guias para la prestacion de servicios. La cuarta edicion de este util recurso reemplaza las ediciones anteriores y se ha actualizado y ampliado por completo. Incluye mas de 86 recomendaciones nuevas y 165 actualizaciones de las recomendaciones emitidas en la edicion anterior. En la presente edicion se brinda orientacion para poblaciones con necesidades especiales, y en un nuevo anexo, se detalla la evidencia sobre las interacciones farmacologicas como consecuencia del uso concomitante de terapias antirretrovirales y anticonceptivos hormonales. A modo de ayuda para los usuarios familiarizados con la tercera edicion, las recomendaciones nuevas y las actualizadas aparecen resaltadas. Se recomienda a todos aquellos que participen en la prestacion de servicios de planificacion familiar y anticoncepcion tener a mano la cuarta edicion Criterios medicos de elegibilidad para el uso de anticonceptivos."