Protecting the reproductive potential of young patients undergoing cancer therapy is increasingly important. With modern treatment protocols, 80% of patients can be expected to survive. It has been estimated that up to one in 250 young adults will be a survivor of childhood cancer in the future; infertility, however, may be a consequence. As a wide range of fertility preservation methods are increasingly offered by clinicians, this systematic and comprehensive textbook dealing with the cryobiology, technology and clinical approach to this therapy will be essential reading to infertility specialists, embryologists, oncologists, cryobiologists, ObGyns, andrologists, and urologists with an interest in fertility preservation. Fertility Cryopreservation reviews all the techniques of this increasingly important field within reproductive medicine. It covers the basic principles of pertinent cryobiology, and contains major sections on the different therapies available, written by international specialists combining experience from both academic centers and commercial industries.

Artificial Insemination and Treatment of Infertility in Dairy Animals by Honnappagol and Tandle is a handy work of 16 well experienced faculties drawn from different departments of higher learning. Most of them are actively engaged in under-graduate and post-graduate teaching with considerable expertise. Adequate care has been exercised by the editors to incorporate all the aspects of artificial insemination and infertility in the chapters form 1 to 20 so that it can serve as a real guide to the students and veterinarians and in turn minimizing the possible economic losses to the dairy animal owners and dairy Industry. Adequate care has been taken to include all spheres of infertility starting from endocrinology of estrous cycle, role of nutrition, feed formulation, breeding strategies, estrus detection aids, recent advances in reproduction controlled breeding, fertility improvement use of ultrasound and laparoscopy, therapeutic management of infertility and reproductive disease control. Practical knowledge and skill in respect of handling, storage and evaluation of frozen semen, safety handling of cryocans and liquid nitrogen, factors affecting success rate in artificial insemination programme and drugs and hormones used in treating reproductive disorders is also provided.

Having a baby can be one of the most wonderful times of your life -- but if you need help to conceive, it can swiftly become a staggeringly expensive undertaking. With the average cost of infertility treatments ranging from $35,000 to $85,000 in the United States (most of which is "not" covered by insurance companies), many women and couples find themselves having to make difficult choices about building their families.

Getting a grip on your finances is one of the few things you can do to regain control of this process. Infertility experts Evelina Weidman Sterling and Angie Best-Boss have created the ultimate guide to ensuring the most cost-effective care with the highest chances for success. With anecdotes, interviews, and advice from both doctors and patients, you can easily apply these specific money-saving strategies to your own unique situation. Learn how to:

- Select a fertility clinic with a high rate of success

- Convince your insurance company to cover more of the costs

- Track down the most affordable fertility drugs

- Travel abroad for cheaper care or international surrogacy

- Avoid the scams and unnecessary expenses every step of the way

Personal and professional, "Budgeting for Infertility" is an invaluable resource that shows you how to pay for infertility treatment...and still have money in the bank for diapers and day care.

The goal of this work was the development of a biomechanical model of the human eye. The research work SEE-KID (Software Engineering Environment for Knowledge based Interactive Eye motility Diagnostics), described in this work, tries to connect aspects of biomechanical modelling with methods of modern Software Engineering. An interactive software system was implemented, called SEE++ which allows physicians to obtain a better understanding of the mechanics of eye movements. This software visualizes and simulates pathologies and eye muscle surgeries, based on the biomechanics of the eye. It can be used in preoperative planning, medical training and basic research, and shows how Medical-Informatics can improve the diagnosis and treatment of patients. The project SEE-KID is based also on the software system Orbit (www.eidactics.com) and on other biomechanics software. The SEE-KID project and the SEE++ software system are meant as extension to Orbit with more clinical relevance while providing essential functionality similar to what Orbit offered. Additionally, SEE-KID tries to extend existing functionality and combine different aspects of modelling into one single system.

As Louise Brown -- the first baby conceived by in vitro fertilization -- celebrates her 30th birthday, Margaret Marsh and Wanda Ronner tell the fascinating story of the man who first showed that human in vitro fertilization was possible.

John Rock spent his career studying human reproduction. The first researcher to fertilize a human egg in vitro in the 1940s, he became the nation's leading figure in the treatment of infertility, his clinic serving rich and poor alike. In the 1950s he joined forces with Gregory Pincus to develop oral contraceptives and in the 1960s enjoyed international celebrity for his promotion of the pill and his campaign to persuade the Catholic Church to accept it.

Rock became a more controversial figure by the 1970s, as conservative Christians argued that his embryo studies were immoral and feminist activists contended that he had taken advantage of the clinic patients who had participated in these studies as research subjects.

Marsh and Ronner's nuanced account sheds light on the man behind the brilliant career. They tell the story of a directionless young man, a saloon keeper's son, who began his working life as a timekeeper on a Guatemalan banana plantation and later became one of the most recognized figures of the twentieth century. They portray his medical practice from the perspective of his patients, who ranged from the wives of laborers to Hollywood film stars.

The first scholars to have access to Rock's personal papers, Marsh and Ronner offer a compelling look at a man whose work defined the reproductive revolution, with its dual developments in contraception and technologically assisted conception.

'Quite simply the best book about science and life that I have ever read' - Alice Roberts How does life begin? What drives a newly fertilized egg to keep dividing and growing until it becomes 40 trillion cells, a greater number than stars in the galaxy? How do these cells know how to make a human, from lips to heart to toes? How does your body build itself? Magdalena Zernicka-Goetz was pregnant at 42 when a routine genetic test came back with that dreaded word: abnormal. A quarter of sampled cells contained abnormalities and she was warned her baby had an increased risk of being miscarried or born with birth defects. Six months later she gave birth to a healthy baby boy and her research on mice embryos went on to prove that - as she had suspected - the embryo has an amazing and previously unknown ability to correct abnormal cells at an early stage of its development. The Dance of Life will take you inside the incredible world of life just as it begins and reveal the wonder of the earliest and most profound moments in how we become human. Through Magda's trailblazing research as a professor at Cambridge - where she has doubled the survival time of human embryos in the laboratory, and made the first artificial embryo-like structures from stem cells - you'll discover how early life is programmed to repair and organise itself, what this means for the future of pregnancy, and how we might one day solve IVF disorders, prevent miscarriages and learn more about the dance of life as it starts to take shape. The Dance of Life is a moving celebration of the balletic beauty of life's beginnings.

An age old mystery, the development of the microscopic embryo into exceedingly complex plants and animals--into roses and cacti, elephants and blue whales, apes and human beings--stands as one of the most fundamental and important questions facing modern biologists. How does one cell give rise
to so many millions of cells? How do they divide so as to form hearts, brains, eyes, and ears? Where in this pin-head-sized object is all this information encoded? Now, in The Triumph of the Embryo, biologist Lewis Wolpert answers these and other questions in a lucid tour of embryology, which offers
the latest theories in this fascinating field.
Filled with rich and unusual examples, metaphors, and descriptions, Wolpert moves beyond his overall narrative to discuss the many issues it raises, such as aging, cancer, regeneration, and evolution. Readers discover why all calico cats are female; encounter a fruit fly engineered to grow a leg
out of its head; and find out why there seems to be a 110 year age barrier for the human body. Clearly written and illustrated with striking examples, The Triumph of the Embryo offers a dazzling look at the marvels of modern biology.

This scarce antiquarian book is included in our special Legacy Reprint Series. In the interest of creating a more extensive selection of rare historical book reprints, we have chosen to reproduce this title even though it may possibly have occasional imperfections such as missing and blurred pages, missing text, poor pictures, markings, dark backgrounds and other reproduction issues beyond our control. Because this work is culturally important, we have made it available as a part of our commitment to protecting, preserving and promoting the world's literature.

Now in a completely newly revised and expanded second edition, this comprehensive text presents the current state of the art in our understanding and management of polycystic ovary syndrome (PCOS), the most common hormonal disorder of reproductive aged women. The numerous bothersome symptoms of PCOS include menstrual irregularities, hirsutism, acne, scalp hair thinning, weigh excess and infertility; additionally, as they age, women with PCOS are at a higher risk for metabolic abnormalities such as diabetes and dyslipidemias, as well as for cardiovascular disease and even certain cancers. Despite improvements in our understanding of this condition, the exact cause/s of PCOS remain elusive; genetic, hormonal, metabolic and environmental underpinnings are all suggested as relevant. All chapters have been updated, with eight new chapters added across seven thematic sections. Part one discusses the epidemiology of PCOS in both adults and adolescents. Part two covers the pathophysiology of PCOS, including genetics, the hypothalamo-pituitary-ovarian and the hypothalamo-pituitary-adrenal axes, insulin resistance, inflammation, and obesity. The next three sections present the various management strategies, medical and surgical, for harnessing the symptomatology, including PCOS-related infertility; these chapters include added case material to provide real-world examples of the treatments in action and their efficacy. Part six covers the comorbidities that women with PCOS commonly encounter, such as issues of mental health, sleep disturbances, endometrial hyperplasia, and cancer, as well as examines the economic burden of PCOS. The final section discusses emerging concepts surrounding possible mechanisms and potential therapeutic approaches to PCOS, including angiogenic dysfunction, the role of vitamin D, future potential therapies to targeted AMH signaling. The closing chapter, by familiarizing the readers with the intergenerational implications of PCOS and by raising awareness of potential "ripple effects", aims at alerting the community on a need for vigilance as regards the health of PCOS progeny. With contributions from leaders in the field, Polycystic Ovary Syndrome, Second Edition remains the gold-standard text on this common medical condition and a valuable resource for the wide range of healthcare professionals engaged in caring for the women with PCOS (including but not limited to reproductive endocrinologists, gynecologists, family physicians, dermatologists, mental health professionals), for the aspiring women's health providers of tomorrow, and for the researchers who are striving to unravel the mysteries of the complex entity that PCOS is.

This scarce antiquarian book is included in our special Legacy Reprint Series. In the interest of creating a more extensive selection of rare historical book reprints, we have chosen to reproduce this title even though it may possibly have occasional imperfections such as missing and blurred pages, missing text, poor pictures, markings, dark backgrounds and other reproduction issues beyond our control. Because this work is culturally important, we have made it available as a part of our commitment to protecting, preserving and promoting the world's literature.

This atlas presents a series of photographic illustrations and line drawings that summarize the major developmental events that occur during organogenesis in the opossum (Didelphis virginiana).It will be of interest to General Biologists, Zoologists, Wildlife Biologists, Embryologists and Medical Scientists.

Say "biological clock" and most people think "women." Yet men have biological clocks too, reveals Dr. Harry Fisch, one of the country's leading experts in male infertility and author of this groundbreaking new book, "The Male Biological Clock." Men's clocks tick at a different rate from women's and of course cause an entirely different set of bodily and behavioral changes over the course of a lifetime. But while men's clocks don't strike a "midnight" toll heralding an end to fertility the way menopause does for women, male fertility, testosterone levels, and sexuality all do decline with age. Dr. Fisch's book emphasizes that even young men can have testosterone levels as low as those of much older men, leading to infertility, sexual problems, and other serious health issues. Another startling revelation is that men over thirty-five are twice as likely to be infertile as men younger than twenty-five. In addition, as men age, the quality of their sperm declines significantly, giving rise to an increased chance of a Down syndrome baby, other genetic abnormalities, and miscarriage. Every couple should know all the risks and issues facing men, because these affect two of the most important things in their life: their ability to have children and their capacity to have good sex.

"The Male Biological Clock" is must reading for every man and every couple who is struggling to have children or improve their sex life. Many of Dr. Harry Fisch's findings are startling -- beginning with the fact that infertility is not mostly a women's problem -- and he offers many helpful suggestions for how to deal with declining testosterone, changing sexual needs, and the fertility industry.

We have allheard stories of men becoming fathers in their seventies or even eighties, yet most of us are unaware that these are dangerously deceptive exceptions. Older men face a number of increased risks as fathers, and often find their sex lives and well-being changing considerably. The good news: Much can be done to slow down and even reverse the effects of a man's biological clock. "The Male Biological Clock" tells you what you need to know and how you can achieve optimal fertility and sexuality.

Combining attention to lived experience with the critical tools of ethics, Karey Harwood explores why many women who use the tools of high-tech assisted reproduction tend to use them repeatedly, even when the results are unsuccessful. With a compassionate look at the individual decision making behind the desire to become pregnant and the use of assisted reproductive technologies (ART), Harwood extends the public conversation beyond debates about individual choice by considering the experiences of families and by addressing the broader ethical problems presented by these technologies. Incorporating the personal narratives of women who are members of RESOLVE, the nation's leading organization for people who are infertile, Harwood demonstrates that repeated unsuccessful attempts to use ART may ironically help women come to terms with their infertility. Yet ART is problematic for a number of reasons, including the financial, physical, and emotional costs for women and their families as well as the effects of these technologies on the health and well-being of the children conceived. Issues such as consumerism, workplace norms that encourage delayed childbearing, and narrow definitions of family all come into play. By considering both emotional and ethical dimensions, Harwood offers a humanistic account of infertility and its resolution in a twenty-first-century American context.

Personalized medicine is what this book is about-tailoring your lifestyle, food, medicines, treatments, and reproductive choices to your genetic signature. According to Dr. Andrew Y. Silverman, MD, PhD, 'The desire to influence the sex of the next child is probably as old as recorded history."

'Gender selection is possible because of the way in which sex is determined by our chromosomes. Dr. Ericsson devised patented methods by which X and Y sperm can be separated through filtering processes. Sperm are 'layered" over a column of human serum albumin, and they swim down the gradient where they are collected in the bottom layer.

'The fraction of sperm that contains the male (Y) bearing sperm is used for insemination if a boy is desired. It is effective 70-75% of the time.

'The fraction of sperm that contains the female (X) bearing sperm is used for insemination if a girl is desired. It is effective 70-72% of the time."

Use personalized medicine more effectively. Empower consumers by interpreting DNA testing and learning more about infant gender choice by genetics.

Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, autoimmune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This book brings together leading research from throughout the world with particular focus on stem cells and cancer research.

This Medical thriller opens with the birth of a severely disfigured child the details the history of the main characters starting from their meeting at one of the most historic footraces in the world - The Dipsea Race. Their courtship begins with conflict but grows into one that will inspire readers to achieve in their own relationships. The novel encompasses three decades and dramatically unfolds after a seemingly small error occurs in a frozen sperm sample. As we embark on the 21st century sometimes ethical issues lag behind the swift pace of medical technology. Readers will grasp the premise of Frozen Identity and enjoy the ride. The main characters are competitive athletes, adding texture, drama and a common bond held by all who strive for physical accomplishment

Winner, 2007 Rachel Carson Prize given by the Society for Social Studies of Science (4S). Assisted reproductive technology (ART) makes babies and parents at once. Drawing on science and technology studies, feminist theory, and historical and ethnographic analyses of ART clinics, Charis Thompson explores the intertwining of biological reproduction with the personal, political, and technological meanings of reproduction. She analyzes the "ontological choreography" at ART clinics--the dynamics by which technical, scientific, kinship, gender, emotional, legal, political, financial, and other matters are coordinated--using ethnographic data to address questions usually treated in the abstract. Reproductive technologies, says Thompson, are part of the increasing tendency to turn social problems into biomedical questions and can be used as a lens through which to see the resulting changes in the relations between science and society. After giving an account of the book's disciplinary roots in science and technology studies and in feminist scholarship on reproduction, Thompson comes to the ethnographic heart of her study. She develops her concept of ontological choreography by examining ART's normalization of "miraculous" technology (including the etiquette of technological sex); gender identity in the assigned roles of mother and father and the conservative nature of gender relations in the clinic; the naturalization of technologically assisted kinship and procreative intent; and patients' pursuit of agency through objectification and technology. Finally, Thompson explores the economies of reproductive technologies, concluding with a speculative and polemical look at the "biomedical mode ofreproduction" as a predictor of future relations between science and society.

This book presents a groundbreaking new method that doubles the rates of spontaneous ovulation and significantly improves fertility. Infertility is a growing concern for large portions of the population. Of women aged 15-44, 6.1 million have impaired fertility and 9.3 million women have made use of fertility services. "Fertility Foods" creates a prescriptive programme that increases ovulation, reduces the chance of miscarriage, and significantly improves a couple's probability of successfully getting, and staying, pregnant. From one of the most respected experts in reproductive endocrinology comes this groundbreaking, non-invasive, nutritionally-based method. Groll's specialised research has shown that high insulin levels can hinder normal ovulation and impact a pregnancy's ability to attach to the uterus. "Fertility Foods" combines its nutritional plan with a specific exercise programme that enhances insulin metabolism, this oft-ignored barrier to fertility. Whether couples are taking their first steps in combating infertility or are searching for effective methods to support more advanced fertility treatments, this essential guide is helpful and rewarding for every couple trying for a child.

Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This book brings together leading research from throughout the world in this frontier field.

All persons, while different from one another, have the same value: this is the author's relatively uncontroversial starting point. Her end point is not uncontroversial: an ideal of justice as human flourishing, based on each person's unique set of capabilities. Because the book's focus is women's health care, gender justice, a necessary component of justice, is central to examination of the issues. Classical pragmatists and feminist standpoint theorists are enlisted in support of a strategy by which gender justice is promoted. Two features of the book are unique: (1) the topics presented cover the entire life span of women, not just those related to reproduction; (2) a range views about moral status are applied not only to fetuses but also to individuals already born. Attention to these features is intended to facilitate ethical consistency or moral integrity and respect for those who hold different moral views. While delineating and defending the book's perspective, the first section provides an overview of bioethics, critiques prevalent approaches to bioethics and models of the physician-patient relationship, and sketches distinguishing aspects of women's health care that are prevalently neglected. Positions about moral status are also presented. The second section identifies topics that are indirectly as well as directly related to women's health, such as domestic violence and caregiving. Brief cases illustrate variables relevant to each topic. Empirical and theoretical considerations follow each set of cases; these are intended to precipitate more expansive and critical examination of the issues raised. The last section is devoted to an egalitarian ideal that may be pursued throughan ethic of virtue or supererogation rather than obligation. By embracing this ideal, according to the author, moral agents support a more demanding level of morality than guidelines or laws require.

Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This book brings together leading research from throughout the world in this frontier field.

This title contains a book and CD. The brain has a number of nerve cells estimated at a magnitude of 10 to 100 billion, and 1014 to 1015 synapses, and therefore is the most complex organ of the human body. During fetal development the foundations of the brain are laid as billions of neurons form appropriate connections and patterns. In the adult mammalian brain, most neurons are post-mitotic, and therefore at risk for irreversible damage. As we age, atrophy of the brain occurs. As brain weight declines the volume of the brain in the 8th decade is reduced by 6 per cent -10 per cent versus the third decade, and neuronal loss occurs, up to 10,000 to 100,000 neurons are lost per day, though this estimation is being revised downward with the advance of more sophisticated measurements.

This is the highly acclaimed book by Robin Marantz Henig about the early days of in vitro fertilization (IVF) and the ethical and legal battles waged in the 1970s, as well as the scientific advances that eventually changed the public perception of 'test tube babies'. Published in paperback for the first time, this timely and provocative book brilliantly presents the scientific and ethical dilemmas in the ongoing debate over what it means to be human in a technological age. About the author: Robin Marantz Henig is the author of eight books. Her previous book The Monk in the Garden: The Lost and Found Genius of Gregor Mendel, was a finalist for the National Book Critics Circle Award. She writes about science and medicine for the New York Times Magazine, where she is a contributing writer, as well as for publications such as Scientific American, Smithsonian, and The Washington Post. Robin Henig garnered two prestigious awards in 2006: the Science in Society Award, the highest honor in science journalism, awarded by the National Association of Science Writers, and The Watson Davis and Helen Miles Davis Prize awarded by The History of Science Society for the best book in the history of science for general readers.

New medical technology as reported in Preventing Miscarriage; The Good News pinpoints the causes and latest treatments available to prevent loss of pregnancy. This book presents a great deal of information in a sensitive, accessible and thorough manner. Illustrations.

Who does a woman turn to when, more than anything in the world, she wants to have a child, but her body refuses to cooperate? Sometimes, all you need is a miracle. In 1998, when thirty-seven-year-old Sandra Watson Rapley and her husband Craig married, both decided that they wanted children right away. Sandra expected some difficulty trying to conceive because of uterine fibroids she had removed years ago. However, she was not prepared for the turbulent - and often times disappointing - road she would have to travel to make her dream a reality. After many failed attempts at drug therapy, ovulation calculation, and in-vitro fertilization, the Rapleys finally learned the devastating truth - fibroids inside Sandra's uterus were preventing a successful pregnancy. Following months of discussion, testing, and counseling, the miracle that the Rapleys were praying for arrived in the form of a surrogate. Their sister-in-law, Victoria, selflessly volunteered to be their embryo's oven, and on August 29, 2001, Victoria gave birth to the Rapleys twin sons. Sandra Watson Rapley's struggle with infertility, through the emotional highs and lows and the exciting time when her dream of having a child is finally fulfilled.