"Original, important, moving, witty and exquisitely-written. WHAT a feat." - BERNARDINE EVARISTO "Incredible... beautiful and funny and humane." - EMILIE PINE "Pristine poetry and prose." KATHERINE MAY, AUTHOR OF WINTERING "I've read a beautiful perfect book. If you are straight or gay, read it." PHILIPPA PERRY "Babies who are this small, he says, have a good chance of survival. Small is not good for babies. It is not whimsical or cute or the cause of admiration. It is the first time it occurs to us that they might not survive. Babies die from smallness." Claire Lynch knew that having children with her wife would be complicated but she could never have anticipated the extent to which her life would be redrawn by the process. This dazzling debut begins with the smallest of life's substances, the microscopic cells subdividing in a petri dish in a fertility treatment centre. She moves through her story in incremental yet ever growing steps, from the fingernail-sized pregnancy test result screen which bears two affirmative lines to the premature arrival of her children who have to wear scale-model oxygen masks in their life-saving incubators. Devastatingly poignant and profoundly observant - and funny against the odds - Claire considers whether it is our smallness that makes our lives so big.

One out of every six patients in the United States is treated in a Catholic hospital that follows the policies of the U.S. Conference of Catholic Bishops. These policies prohibit abortion, sterilization, contraception, some treatments for miscarriage and gender confirmation, and other reproductive care, undermining hard-won patients’ rights to bodily autonomy and informed decision-making. Drawing on rich interviews with patients and providers, this book reveals both how the bishops’ directives operate and how people inside Catholic hospitals navigate the resulting restrictions on medical practice. In doing so, Bishops and Bodies fleshes out a vivid picture of how The Church’s stance on sex, reproduction, and “life” itself manifests in institutions that affect us all.

Developmental biologists have been driven to investigate growth factor signaling in embryos in order to understand the regulatory mechanisms underlying a given developmental process. Thus, it is critical to explore the technical methods and experimental designs for growth factor signaling in embryos.

Focusing on specific pathways or pathway components, Analysis of Growth Factor Signaling in Embryos provides the methods and guidelines for experimental design to study major aspects of cell signaling in vertebrate embryos. The book covers a broad range of topics in signaling and a variety of current model organisms. Section I explores specific signaling pathways or pathway components. In this section, some chapters highlight the biochemistry of signaling pathways during development, which is often distinctive from that observed in cell culture systems. Section II discusses ionic regulatory mechanisms and the two chapters in Section III examine ways of investigating gene regulation in response to extracellular signals. Finally, Section IV addresses emerging strategies that facilitate integrated analyses of cell signaling" in vivo" in embryonic systems.

Featuring contributions from expert researchers, Analysis of Growth Factor Signaling in Embryos will provide a foundation for further explorations of the cellular regulatory mechanisms governing vertebrate embryonic development.

The experiences of infertility and childlessness, while not worse than other griefs and disappointments people experience, are nevertheless distinctive in a number of important respects. Unlike other griefs, they often take place in private, with no body, no funeral, and no public acknowledgement of the loss. In her profound and wise theology of childnessness, Emma Nash takes her own story as a starting point, examining several distinctive features of this painful human experience. She asks what biblical and theological resources offer consolation, and what liberative action individuals and churches might take to make an appropriate response. Weaving trauma theology together with personal experience, Nash offers a profound and heartfelt theological reflection which breaks the barriers between pastoral resource and carefully constructed theology.