THE SUNDAY TIMES BESTSELLER, now with an extra chapter. 'All I ever wanted was to be a mum - I couldn't wait and it felt as though my time was so close. But the months started to tick by, with each one ending in disappointment and frustration. And then the inevitable panic started to set in ...' Having been told by doctors that, due to Izzy's polycystic ovarian syndrome, they would have difficulty conceiving - and after two years of trying - Izzy and her husband, Harry, turned to IVF. Izzy's aim is to break through some of the taboos surrounding miscarriage, IVF and fertility issues. This brutally honest and deeply personal account acknowledges the struggles that many couples go through but will ultimately focus on the positive, life-changing results that IVF can yield. Izzy hopes that this book will be a companion to those going through similar challenges to those she has experienced. As she herself says, 'No couple should have to go through it alone and in silence.'

Practical Management of Ovulation Induction is a concise resource for postgraduate students, infertility specialists and gynaecologists. Divided into seventeen chapters, the book begins with the physiology and regulatory factors of ovulation, and proceeds to cover topics such as ovarian hyperstimulation syndrome, premature ovarian failure, and a variety of ovulation induction therapies including new drugs. The book concludes with chapters on the surgical management of anovulation, oocyte donation, ovarian transplant and surrogacy. This book features new clinical applications for old medications, and discussion on various treatment combinations, as well as new drugs such as Anastrozole. Discussion on complications of ovulation induction and strategies to avoid them, are also included. Illustrated throughout, Practical Management of Ovulation Induction is an invaluable tool to assist practitioners in the selection of appropriate ovulation induction treatment. Key Points Concise guide to the selection and administration of ovulation induction therapies Includes new therapies, drugs and treatment combinations 41 images and illustrations

Public concern over high-profile mistakes in IVF clinics and the concomitant increase in governmental regulation, have given rise to widespread recognition of the need for accreditation of IVF clinics. Modern accreditation schemes are largely based on the principles of ISO 9001 and related standards, at the heart of which lies the expectation of a formal quality management system. Risk analysis and risk minimization are also being demanded of IVF clinics, but many only have limited understanding of how to approach these essential management tasks. This book brings together the basics of quality management and risk management, focussing on 'prophylactic management' - prevention rather than cure. Each chapter in this new edition is fully updated and extended to include new material such as, quality and risk management in the ART clinic, and an illustrative example of a 'well-run' clinic. This is the essential guide for clinicians and IVF laboratory staff.

First published in 1959 as the second edition of a 1934 original, this book describes the Western history of embryology from prehistoric concepts of foetal growth through Graeco-Roman antiquity to the close of the eighteenth century. The text is illustrated with plates and diagrams showing the development of scientific understanding over time, first through artistic representations of gestation and later through scientific drawings and sketches. This book will be of value to anyone with an interest in the history of medicine.

El problema de la esterilidad e infertilidad en las parejas hoy dia esta poniendo en riesgo la capacidad de reemplazo generacional en Europa. Segun la Organizacion Mundial de la Salud (OMS), alrededor del 10 al 15% de las parejas en edad de procrear consultan al medico por problemas de esterilidad. El objetivo de este manual es actualizar los conocimientos y adiestrar en los procedimientos para evaluar la calidad del semen, ayudar al diagnostico de la subfertilidad y esterilidad de origen masculino. Va dirigido al personal en formacion y a profesionales del ambito sanitario, principalmente del laboratorio (tecnicos y facultativos) pero tambien a los clinicos prescriptores (urologos y ginecologos).

Est ce que l'avortement est un crime ou un droit? C'est peut etre la question que tu te poses et a la quelle tu n'as pas encore trouve de reponse. La lecture de cette brochure te donnera une idee Claire sur l'avortement de maniere a pouvoir repondre a cette question.

Omdat mensen nietzelf kunnen kiezen volgens welk receptzijhun kinderwens vorm geven, is begnip en respect erg belangrijk. Dit boekje is een schitterend instrument om kinderen te introduceren in de complexe wereld van fertiliteitsbehandelingen. Het ontdoet de problematiek van de taboes waarmee fertilieteitsbehandelingen vaak nog zijn omgeven en helpt inzien dat het niet uitmaakt volgens welk recept je op de wereld gekomen bent. Kortom, een aanrader voor groot en klein"

Forms of embodied labor, such as surrogacy and participation in clinical trials, are central to biomedical innovation, but they are rarely considered as labor. Melinda Cooper and Catherine Waldby take on that project, analyzing what they call "clinical labor," and asking what such an analysis might indicate about the organization of the bioeconomy and the broader organization of labor and value today. At the same time, they reflect on the challenges that clinical labor might pose to some of the founding assumptions of classical, Marxist, and post-Fordist theories of labor.
Cooper and Waldby examine the rapidly expanding transnational labor markets surrounding assisted reproduction and experimental drug trials. As they discuss, the pharmaceutical industry demands ever greater numbers of trial subjects to meet its innovation imperatives. The assisted reproductive market grows as more and more households look to third-party providers for fertility services and sectors of the biomedical industry seek reproductive tissues rich in stem cells. Cooper and Waldby trace the historical conditions, political economy, and contemporary trajectory of clinical labor. Ultimately, they reveal clinical labor to be emblematic of labor in twenty-first-century neoliberal economies.

Forms of embodied labor, such as surrogacy and participation in clinical trials, are central to biomedical innovation, but they are rarely considered as labor. Melinda Cooper and Catherine Waldby take on that project, analyzing what they call "clinical labor," and asking what such an analysis might indicate about the organization of the bioeconomy and the broader organization of labor and value today. At the same time, they reflect on the challenges that clinical labor might pose to some of the founding assumptions of classical, Marxist, and post-Fordist theories of labor.
Cooper and Waldby examine the rapidly expanding transnational labor markets surrounding assisted reproduction and experimental drug trials. As they discuss, the pharmaceutical industry demands ever greater numbers of trial subjects to meet its innovation imperatives. The assisted reproductive market grows as more and more households look to third-party providers for fertility services and sectors of the biomedical industry seek reproductive tissues rich in stem cells. Cooper and Waldby trace the historical conditions, political economy, and contemporary trajectory of clinical labor. Ultimately, they reveal clinical labor to be emblematic of labor in twenty-first-century neoliberal economies.

A memoir of hope for the thousands of women struggling with infertility, from one who beat the odds by simply tuning in to her body and tapping her well of sheer determination.

At a time when more and more women are trying to get pregnant at increasingly advanced ages, fertility specialists and homeopathic researchers boast endless treatment options. But when Julia Indichova made the rounds of medical doctors and nontraditional healers, she was still unable to conceive a child. It was only when she forsook their financially and emotionally draining advice, turning inward instead, that she finally met with reproductive success. Inconceivable recounts this journey from hopeless diagnoses to elated motherhood.

Anyone who has faced infertility will relate to Julia’s desperate measures: acupuncture, unidentifiable black-and-white pellets, herb soup, foul-smelling fruit, even making love on red sheets. Five reproductive endocrinologists told her that there was no documented case of anyone in her hormonal condition getting pregnant, forcing her to finally embark on her own intuitive regimen. After eight caffeine-free, nutrient-rich, yoga-laden months, complemented by visualization exercises, Julia received amazing news; incredibly, she was pregnant. Nine months later she gave birth to a healthy girl.

Unlike the many infertility books that take a clinical “how to” approach, Inconceivable simply professes the wisdom of giving expert status back to the patient. Julia’s self-discovery, and her ability to see her body as an ally once again, yield a beautiful message about the importance of honoring the body’s innate powers, and the power of life itself.

Historically, sperm have been seen as simply a mechanism of transferring a haploid set of chromosomes to the oocyte. However, data from assisted reproduction therapies (ART) have demonstrated that in many couples the sperm appears to be responsible for abnormal embryogenesis. Recent advances in genetic and epigenetic techniques have identified key mechanisms by which the sperm, and the DNA carried by the sperm, can affect early embryonic development. Paternal Influences on Human Reproductive Success examines the genetic and epigenetic influences on embryogenesis, as well as practical clinical factors related to the male contribution to reproductive success. It also provides 'cutting edge' data and analysis of recent evaluations of the role of advanced paternal age, environmental influences and lifestyle factors on male reproductive fitness, making this an invaluable text for physicians treating patients for infertility, recurrent pregnancy loss, and developmental anomalies, as well as basic scientists studying embryogenesis and spermatogenesis.

Founded in 1914, the Department of Embryology of the Carnegie Institution of Washington has made an unparalleled contribution to the biological understanding of embryos and their development. Originally much of the research was carried out through experimental embryology, but by the second half of the twentieth century, tissue and cell cultures were providing histological information about development, and biochemistry and molecular genetics have taken center stage. This final volume in a series of five histories of the Carnegie Institution of Washington provides a history of embryology and reproductive biology spanning a hundred years. It provides important insights into the evolution of both scientific ideas and the public perception of embryo research, concluding with a reflection on current debates.

This practical 2003 handbook provides an extremely comprehensive and highly illustrated guide to micromanipulation techniques in assisted conception in a clinical setting. It includes detailed, illustrated descriptions of all the common micromanipulation systems currently in use in IVF laboratories around the world and clearly explains how to optimise their successful use. The volume covers state-of-the-art techniques including intracytoplasmic sperm injection (ICSI), and procedures such as assisted hatching and the blastomere biopsy (for preimplantation genetic diagnosis PGD). Valuable information on troubleshooting the potential mechanical and technical difficulties that can arise is provided to help all the practitioners of these techniques, including trainee embryologists and consultant obstetricians, and technicians and scientists involved in animal transgenesis and cloning. It will undoubtedly be of immense value to all doctors and scientists working with assisted reproductive technologies.

Originally published in 2006, this book provides an in-depth account of trophoblast: the tissue derived from the fertilised egg that nourishes and protects the developing fetus. The cells of the trophoblast have many unique qualities, and exhibit great variability across different species. It has a fascinating role in the development of the placenta and as a regulator during early growth of the embryo. These aspects are all fully covered as well as studies on why it is not rejected by the mother as 'foreign' tissue. Disorders of trophoblast during development also manifest themselves in several clinical conditions during pregnancy, including gestational trophoblastic disease and pre-eclampsia. From stem cells through to epigenetics, implantation and X-chromosome inactivation, there is a lot to be learned about trophoblast, this volume provides a detailed summary of knowledge regarding the subject.

IVF is now established worldwide as a clinical service. Units are striving to improve their success rates, and many treatments are being advocated as 'yet another breakthrough'. The purpose of this book is to help clinicians to evaluate each of these new treatments. Each chapter is written by a recognized international expert in the field and the chapters are short and succinct, summarizing the latest evidence-based information for each topic and treatment. Sections cover patient selection and preparation, the role of AIH before IVF, stimulation, monitoring, laboratory techniques, embryo transfer, ancillary treatments and assessment of results. How to Improve your ART Success Rates: An Evidence-Based Review of Adjuncts to IVF is essential reading for all clinicians working with infertility and assisted reproduction, and is also a valuable addition to any medical library.