Reports on the study of drug consumption by 602 pregnant women.

Senior investigators internationally have here collaborated to produce an international reference work. Each contributor provides critical and thought provoking concepts and ideas based on the latest developments in their field. The result is a must read and timely reference work for investigators who are interested in how spermatogenesis is currently understood and which are the most promising avenues for future research; an Introduction sets the context for the chapter and points out the relevance of the research for basic research scientists and clinicians.

Long regarded as biological waste, the placenta is gaining momentum as a viable product for clinical use. Due to their unique properties, placental cells and derivatives show great promise in curing various diseases. Utilizing contributions from world-renowned experts, Placenta: The Tree of Life considers the therapeutic potential of these cells. It examines new stem cell-based strategies and highlights recent studies that advance the range of treatment for a number of illnesses. Emphasizing the potential research and therapeutic use of stem cells, the book discusses the development, structure, and functions of the human placenta. It introduces overall aspects of the immune system, explains some of the immune mechanisms during pregnancy, and shows the role of the placenta in these mechanisms. Current scientific research is presented that focuses on the mechanisms of action underlying the therapeutic benefit of cells isolated from different placental regions. An exhaustive examination, this pivotal work: Considers how perinatal cells may represent an important source for cell therapy approaches in the near future, in both human and veterinary medicine Describes the clinical potential of placenta-derived cells in regenerative medicine-specifically in neurological disorders, metabolic liver diseases, inflammatory diseases, and autoimmune diseases Explains how cells isolated from different placental tissues share basic properties Placenta: The Tree of Life summarizes the advantages of perinatal tissue as a source of cells with therapeutic potential and is designed for use in the study of genetics, stem cell science, placental function, reproductive biology, regenerative medicine, and related fields.

"Original, important, moving, witty and exquisitely-written. WHAT a feat." - BERNARDINE EVARISTO "Incredible... beautiful and funny and humane." - EMILIE PINE "Pristine poetry and prose." KATHERINE MAY, AUTHOR OF WINTERING "Babies who are this small, he says, have a good chance of survival. Small is not good for babies. It is not whimsical or cute or the cause of admiration. It is the first time it occurs to us that they might not survive. Babies die from smallness." Claire Lynch knew that having children with her wife would be complicated but she could never have anticipated the extent to which her life would be redrawn by the process. This dazzling debut begins with the smallest of life's substances, the microscopic cells subdividing in a petri dish in a fertility treatment centre. She moves through her story in incremental yet ever growing steps, from the fingernail-sized pregnancy test result screen which bears two affirmative lines to the premature arrival of her children who have to wear scale-model oxygen masks in their life-saving incubators. Devastatingly poignant and profoundly observant - and funny against the odds - Claire considers whether it is our smallness that makes our lives so big.

This issue of Radiologic Clinics of North America focuses on Imaging of the Reproductive Age Female, and is edited by Dr. Liina Poder. Articles will include: Imaging Safety and Technical Considerations in the Reproductive Age Female; Imaging of Infertility: Hysterosalpingograms to MRI; Imaging Spectrum of Benign Uterine Disease and Treatment Options; Imaging of Benign Adnexal Disease; Imaging Spectrum of Endometriosis (Endometriomas to Deep Infiltrative Endometriosis); Imaging of The Female Pelvic Floor: Current Implications and New Horizons; Imaging of Acute Pelvic Pain: Nonpregnant; Imaging of Acute Pelvic Pain: Pregnant (ectopic and first trimester viability updated); Nonfetal Imaging During Pregnancy: Acute Abdomen/Pelvis; Nonfetal Imaging During Pregnancy: Placental Related Disease; Imaging of Gynecologic Malingancy in a Reproductive Age Female: Fertility Sparing; Imaging of Gynecologic Malignancy in A Reproductive Age Female: Cancer During Pregnancy; Imaging of Post/Peripartum Complications; Role of Interventional Procedures in Obstetrics and Gynecology, and more!

Now in its revised and expanded second edition - including over 20 new chapters - this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and systems, respectively. The sections that follow provide detailed descriptions of IVF techniques, embryo culture methods, sperm processing and selection, insemination procedures, micromanipulation, embryo evaluation, cryopreservation, and embryo transfer. Concluding sections address issues of management and regulation of ART labs across the globe, as well as special topics and emerging techniques and devices. Chapter authors, all experts in the field, contribute their expertise from around the world. With the addition of learning key points and review questions at the beginning and end of each chapter, this new edition of In Vitro Fertilization is a readily accessible, high quality instructional resource for reproductive medicine trainees at all levels. Practicing reproductive endocrinologists, urologists, and embryologists also will find value in the book, as will infertility researchers.

Thieme Test Prep for the USMLE (R): Medical Histology and Embryology is the choice of medical students... ...The major test-prep resources do not focus on these subjects in detail. A question bank...would be beneficial to those who struggle with these as an additional resource for studying ... - Ethan Young (Fourth-year medical student, University of South Dakota, Sanford School of Medicine) I especially like the clinical focus of the questions, which are "two layers" deep instead of straight recall. - Deborah Chen (Third-year medical student, Rutgers Robert Wood Johnson Medical School) Well thought out and also extremely well written. ... an effective tool for students both in learning the material initially and also in reviewing it for the USMLE. - Roger A. Dashner, MS, PhD (Clinical Anatomist and CEO, Advanced Anatomical Services) Thieme Test Prep for the USMLE (R): Medical Histology and Embryology fills a void in available board prep materials in its combination of histology and embryology. Consistently organized sections cover everything from microstructures of basic tissue and body systems to the development of all major body systems. Key Highlights Nearly 600 USMLE (R)-style multiple choice questions and detailed explanations, classified by organ system and difficulty level Questions begin with a clinical vignette and approximately 20% are image-based, mirroring the USMLE-format The only resource containing correct proportions of light and electron micrographs for histology, consistent with USMLE (R) testing standards This essential resource will help you assess your knowledge and fully prepare for board examinations.

Regulatory agencies worldwide have issued directives or such requirements for air quality standards in embryology laboratories. This practical guide reviews the application of clean room technology or controlled environments specifically suited for Assisted Reproductive Technology (ART) Units. Its comprehensive coverage includes material on airborne particles and volatile organic compounds, including basic concepts, regulation, construction, materials, certification, clinical results in humans, and more.

Unlike conventional single daily observations, time lapse technology provides hundreds of images, which allows pinpointing of key events in the embryo's in vitro development as well as the detection of brief but significant critical changes. This information is beneficial in selecting the most viable embryos from a cohort and increases the chances of a positive outcome. The Atlas of Time Lapse Embryology describes in detail the technology and techniques surrounding time lapse embryology. The book also covers the clinical aspects of time lapse imaging, morphokinetic timings, implantation data, fertilization, compaction, blastulation, irregular cleavages, multinucleation, vacuolation, zona defects, and other topics. The book is easy to read, practical, and illustrated with dozens of images and video clips to help explain a variety of concepts. It will help practitioners to better understand how time lapse monitoring may dramatically increase flexibility in the IVF clinic, and most importantly, enhance clinical outcomes. Print Versions of this book also include access to the ebook version.

This practical book provides need-to-know information vital for acupuncturists to treat patients with fertility problems. Nick Dalton-Brewer details the causes of fertility issues, including the impact of lifestyle and diet, and explains the scientific basis for the different methods of treatment. Integrating Assisted Reproduction Techniques (ART) with Traditional Chinese Medicine (TCM) therapies and acupuncture, he presents his own cutting-edge research on the successful use of these therapies to improve fertility and pregnancy rates and describes a method for integrated diagnosis and treatment. This book will give TCM practitioners direct access to the vital specialist knowledge and technical information needed to treat the increasing numbers of patients with fertility problems effectively. It will also be of interest to doctors of Western medicine concerned about the efficacy of recommending acupuncture treatments as adjuncts to ART.

This title includes a number of Open Access chapters. Embryology is the study of embryos. It is the branch of biological science that deals with the formation and early development of an individual organism, from fertilization of the egg (ovum) to birth. This collection includes articles on some of the most important topics in embryology today, such as cryopreservation of human embryos, in vitro generation of neurons from embryonic stem cells, embryonic transfer, transcriptional profiling, and more.

Around three quarters of people who turn to adoption do so because of infertility and those working in this field need information, guidance and support to assist them in the process of adoption to support the adopters and to deal with any issues that may result from infertility. Adopting after Infertility is an accessible and informative interdisciplinary book that addresses the issues that professionals working with adopters and the adopters themselves face when going through the adoption process and the impact of infertility on their experiences. The book includes chapters on the effects of infertility, why people may choose adoption and the assessment and preparation process. It also covers what an Adoption Panel needs to know about the prospective parents, the experiences of those coming to adoption from minority communities or when living with health conditions and post-adoption support needs. Personal accounts by people who have experienced adopting after infertility are included throughout the book. This book will be essential reading for professionals and academics from a range of disciplines including social work, psychology, health, mental health and counselling. It will also be invaluable to students studying for post-qualifying awards.

A new subspecialty is growing at the interface of reproductive medicine and perinatology: infertility. Textbook of Periconceptional Medicine provides an authoritative and comprehensive reference resource for those providing medical care to women trying to conceive a healthy pregnancy.

A revolutionary first edition, this text brings together a number of difficult and usually separate topics and provides the busy clinician with one authoritative and methodical reference.

Reflecting the breadth of modern clinical practice in this emerging therapy area, this integrated text incorporates aspects of all the relevant existing expertise, including:

• Preconceptual counseling
• Fertility investigation
• Therapy and management of preconception through the first trimester of pregnancy

The first edition of The Endometrium was a landmark publishing event in reproductive biology and medicine. Many important developments have occurred in the field, and this new edition has been substantially updated and expanded to include new topics with an improved format. With the addition of several new authors and topics, the Second Edition of The Endometrium has developed new coverage of transcriptomics, stem cells, genetics and in-utero programming. Other new areas strengthen to include: placentology in human and animal models, taking account of the tremendous current interest in the maternal-fetal interface and its role in pregnancy pathology, neonatal and adult health. The layout has also been improved in order to aid browsing and cross-referencing. This is an invaluable up-to-date innovative text that will appeal to a worldwide spectrum of academic and professional readers including postgraduate and postdoctoral researchers in reproductive biology. As well as trainees and health care professionals in obstetrics and gynecology and allied disciplines such as assisted reproduction and oncology. A panel of internationally respected authors has been carefully chosen for their insight, clear, fair writing style and scholarly perspective.

Kinetic models are becoming standard tools in the research of biological systems. They are used to represent hypotheses, analyze data, and design experiments to maximize the information obtained from a study. Kinetic Models of Trace Element and Mineral Metabolism During Development describes models for calcium, chromium, copper, iron, iodide, lead, mercury, selenium, zinc, and others in health and disease.

Gain a solid understanding of how to treat infertility with Chinese medicine Written by experts in Chinese medicine, this textbook provides a comprehensive overview of Chinese medicine therapies for fertility disorders. It opens by reviewing the basics of current Western reproductive medicine in terms of diagnosis, treatment options, and possible risks. The book then introduces the reader to traditional Chinese fertility treatments, providing information about how they complement Western reproductive medicine. The authors describe in detail the different treatment methods, ranging from qi gong and tui na to moxibustion and acupuncture to Chinese dietetics and medicinal therapy. The main section of the book provides in-depth discussion of specific fertility disorders and their management, including menstrual disorders, early menopause, sexual disorders, male infertility, endometriosis, and polycystic ovary syndrome. It closes with a section on patient support, addressing issues such as the mind-body relationship and the impact of stress. Key features: Case studies with real-life examples of specific treatment approaches Information on both Chinese and Western therapies. Perspectives from numerous Chinese medicine specialists. Extensive quotations from classical texts in translation. Historical, cultural, and social perspectives on the issue of fertility in Chinese culture, modern and ancient Chinese Medicine in Fertility Disorders is an invaluable resource for practitioners in complementary medicine, including acupuncturists and Chinese herbalists who wish to include fertility treatment in their practice, and a useful reference for all physicians who seek to expand their perspective on managing fertility issues.

If you need help having a baby, reproductive technology can supply the answer. But it also raises a host of questions that won't arise until after the child is born: What will you say to "Where did I come from?" when the answer includes a donor or surrogate? Will knowing the truth about how you conceived make your child love you less? Will having a baby with someone else strain your relationship with your spouse or partner? What will grandparents, family members, friends, and coworkers think? Dr. Diane Ehrensaft--a developmental and clinical psychologist who's worked with families formed using assisted reproductive technology for more than 20 years--helps you anticipate the big questions and find solutions that are right for you and your loved ones. Dr. Ehrensaft offers information, support, and straightforward advice for coping with private worries, confronting public prejudices, and raising happy, healthy children. Single or married, straight or gay, anyone looking forward to the joys and challenges of building a family with the help of a donor or surrogate will discover a wealth of thought-provoking ideas and fresh insights in this sensitive, practical, and positive book.

Impotence is a widespread phenomenon; about half of couples entering sex therapy and one quarter of those entering marital therapy will complain of this problem. As baby boomers enter their fifties and grow older during the next few decades, many more men will be affected by this problem. In this groundbreaking work, Gerald Weeks and Nancy Gambescia present the first serious discussion of comprehensive psychological and medical treatments for erectile dysfunction after the advent of Viagra. Though most recently Viagra has catapulted discussion of erectile dysfunction to the front pages of major newspapers and, via television, American living rooms, there are actually a number of different treatment options available. In fact, medical therapies for erectile dysfunction have developed at an ever-increasing pace in the last 20 years. Yet, despite widespread advances made in the treatment of erectile dysfunction, the field of sex therapy has lagged significantly behind in how it addresses the problem. The authors offer an integrated approach that examines both the organic and psychological factors contributing to erectile dysfunction. With this treatment model integrating both medical and psychological therapies, the authors also stress the role of the couple's relationship in the etiology and treatment of the dysfunction. The book presents medical information (about various kinds of drugs as well as other interventions); physiological information (why certain drugs work and why some don't); psychological information (the effects of the disorder on both the individual and the couple); and practical information (when and how to seek treatment and what type of treatment works best under different conditions). For sex and couple therapists and physicians, Erectile Dysfunction presents a systematic method for evaluating erectile dysfunction, determining whether its basis is primarily organic or psychogenic, and treating it by integrating medical interventions with sex and marital therapy. For the person seeking treatment (and for his spouse), the book offers a thorough and impartial discussion of the disorder.

The annotated bibliography that follows summarizes some of the more important studies that have been published concerning smoking and its effects on the fetus along with reports of the various efforts that have been undertaken to reduce the impact of smoking during pregnancy. The material has been divided into topics to guide the reader and cross-references are included at the end of each section. An Author Index is also included to guide the reader to relevant publications when only an author's name is known. The following comments constitute an overall summary of the literature.

En el documento Criterios medicos de elegibilidad para el uso de anticonceptivos se revisan los criterios medicos de elegibilidad para el uso de anticonceptivos y se ofrece orientacion sobre la seguridad de la utilizacion de diferentes metodos para mujeres y hombres con condiciones medicas conocidas o caracteristicas especificas. Las recomendaciones estan basadas en revisiones sistematicas de investigaciones clinicas y epidemiologicas disponibles. Es una guia complementaria de las Recomendaciones sobre practicas seleccionadas para el uso de anticonceptivos. Juntos, estos documentos estan destinados a responsables de la formulacion de politicas, directores de programas y la comunidad cientifica, con el fin de apoyar a los programas nacionales en la preparacion de guias para la prestacion de servicios. La cuarta edicion de este util recurso reemplaza las ediciones anteriores y se ha actualizado y ampliado por completo. Incluye mas de 86 recomendaciones nuevas y 165 actualizaciones de las recomendaciones emitidas en la edicion anterior. En la presente edicion se brinda orientacion para poblaciones con necesidades especiales, y en un nuevo anexo, se detalla la evidencia sobre las interacciones farmacologicas como consecuencia del uso concomitante de terapias antirretrovirales y anticonceptivos hormonales. A modo de ayuda para los usuarios familiarizados con la tercera edicion, las recomendaciones nuevas y las actualizadas aparecen resaltadas. Se recomienda a todos aquellos que participen en la prestacion de servicios de planificacion familiar y anticoncepcion tener a mano la cuarta edicion Criterios medicos de elegibilidad para el uso de anticonceptivos."