The riveting true story of John and Aileen Crowley's race to find a cure for Pompe disease that inspired the movie Extraordinary Measures

With three beautiful children, a new house, and financial security, John and Aileen Crowley were on top of the world--until their two youngest children, fifteen-month-old Megan and five-month-old Patrick, were diagnosed with Pompe disease and given only months to live. Refusing to accept a death sentence, John quit his financial consultant job and invested his life savings in a biotechnology start-up to research the disease and find a cure. Battling scientific setbacks, conflict of interest accusations, and business troubles, John and Aileen would be tested to their limits as they valiantly fought, and succeeded, in finding revolutionary new treatment for the disease--offering hope to Megan, Patrick, and the many children and families affected by Pompe disease around the world.

The inspiration for the captivating film Extraordinary Measures, starring Brendan Fraser and Harrison Ford, The Cure is a remarkable true story of cutting-edge science, business acumen and daring, and one family's indomitable spirit.

Soon to be a major motion picture, the story of one of the most improbable and productive collaborations ever chronicled, between a young unschooled Indian prodigy and a great English mathematician.

In 1913, a young unschooled Indian clerk wrote a letter to G H Hardy, begging the preeminent English mathematician's opinion on several ideas he had about numbers. Realizing the letter was the work of a genius, Hardy arranged for Srinivasa Ramanujan to come to England. Thus began one of the most improbable and productive collaborations ever chronicled. With a passion for rich and evocative detail, Robert Kanigel takes us from the temples and slums of Madras to the courts and chapels of Cambridge University, where the devout Hindu Ramanujan, "the Prince of Intuition," tested his brilliant theories alongside the sophisticated and eccentric Hardy, "the Apostle of Proof." In time, Ramanujan's creative intensity took its toll: he died at the age of thirty-two and left behind a magical and inspired legacy that is still being plumbed for its secrets today.

Filled with incident, discovery, and revelation, Dutch Light is a vivid account of Christiaan Huygens's remarkable life and career, but it is also nothing less than the story of the birth of modern science as we know it. Europe's greatest scientist during the latter half of the seventeenth century, Christiaan Huygens was a true polymath. A towering figure in the fields of astronomy, optics, mechanics, and mathematics, many of his innovations in methodology, optics and timekeeping remain in use to this day. Among his many achievements, he developed the theory of light travelling as a wave, invented the mechanism for the pendulum clock, and discovered the rings of Saturn - via a telescope that he had also invented. A man of fashion and culture, Christiaan came from a family of multi-talented individuals whose circle included not only leading figures of Dutch society, but also artists and philosophers such as Rembrandt, Locke and Descartes. The Huygens family and their contemporaries would become key actors in the Dutch Golden Age, a time of unprecedented intellectual expansion within the Netherlands. Set against a backdrop of worldwide religious and political turmoil, this febrile period was defined by danger, luxury and leisure, but also curiosity, purpose, and tremendous possibility. Following in Huygens's footsteps as he navigates this era while shuttling opportunistically between countries and scientific disciplines, Hugh Aldersey-Williams builds a compelling case to reclaim Huygens from the margins of history and acknowledge him as one of our most important and influential scientific figures.

Of the three physicians at the Battle of the Little Big Horn, Doctor George Edwin Lord (1846-76) was the lone commissioned medical officer, an assistant surgeon with the United States Army's 7th Cavalry-one more soldier caught up in the U.S. government's efforts to fulfill what many people believed was the young country's "Manifest Destiny." A Life Cut Short at the Little Big Horn tells Lord's story for the first time. Notable for its unique angle on Custer's last stand and for its depiction of frontier-era medicine, the book is above all a compelling portrait of the making of an army medical professional in mid-nineteenth-century America. Drawing on newly discovered documents, Todd E. Harburn describes Lord's education and training at Bowdoin College in Maine and the Chicago Medical College, detailing what the study of medicine entailed at the time for "a young man of promise . . . held in universal esteem." Lord's time as a contract physician with the army took him in 1874 to the U.S. Northern Boundary Survey. From there Harburn recounts how, after a failed romance and the rigors of the U.S. Army Medical Board examination, the young doctor proceeded to his first-and only-appointment as a post surgeon, at Fort Buford in Dakota Territory. What followed, of course, was Lord's service, and his death, in the Little Big Horn campaign, which this book shows us for the first time from the unique perspective of the surgeon. A portrait of a singular figure in the milieu of the American military's nineteenth-century medical elite, A Life Cut Short at the Little Big Horn offers a close look at a familiar chapter in U.S. history, and a reminder of the humanity lost in a battle that resonates to this day.