300 years ago, in April 1721, a smallpox epidemic was raging in England. Lady Mary Wortley Montagu knew that she could save her 3-year-old daughter using the process of inoculation. She had witnessed this at first hand in Turkey, while she was living there as the wife of the British ambassador. She also knew that by inoculating - making her daughter the first person protected in the West - she would face opposition from doctors, politicians and clerics. Her courageous action eventually led to the eradication of smallpox and the prevention of millions of deaths. But Mary was more than a scientific campaigner. She mixed with the greatest politicians, writers, artists and thinkers of her day. She was also an important early feminist, writing powerfully and provocatively about the position of women. She was best friends with the poet Alexander Pope. They collaborated on a series of poems, which made her into a household name, an 'It Girl'. But their friendship turned sour and he used his pen to vilify her publicly. Aristocratic by birth, Mary chose to elope with Edward Wortley Montagu, whom she knew she did not love, so as to avoid being forced into marrying someone else. In middle age, her marriage stale, she fell for someone young enough to be her son - and, unknown to her, bisexual. She set off on a new life with him abroad. When this relationship failed, she stayed on in Europe, narrowly escaping the coercive control of an Italian conman. After twenty-two years abroad, she returned home to London to die. The son-in-law she had dismissed as a young man had meanwhile become Prime Minister.

Following their New York Times-bestselling graphic novel Feynman, Jim Ottaviani and Leland Myrick deliver a gripping biography of Stephen Hawking, one of the most important scientists of our time. From his early days at the St Albans School and Oxford, Stephen Hawking's brilliance and good humor were obvious to everyone he met. A lively and popular young man, it's no surprise that he would later rise to celebrity status. At twenty-one he was diagnosed with ALS, a degenerative neuromuscular disease. Though the disease weakened his muscles and limited his ability to move and speak, it did nothing to limit his mind. He went on to do groundbreaking work in cosmology and theoretical physics for decades after being told he had only a few years to live. He brought his intimate understanding of the universe to the public in his 1988 bestseller, A Brief History of Time. Soon after, he added pop-culture icon to his accomplishments by playing himself on shows like Star Trek, The Simpsons, and The Big Bang Theory, and becoming an outspoken advocate for disability rights. In Hawking, writer Jim Ottaviani and artist Leland Myrick have crafted an intricate portrait of the great thinker, the public figure, and the man behind both identities.

The enthralling Sunday Times-bestselling biography of the shepherd boy who changed the world with his revolutionary engineering and whose genius we still benefit from today

Thomas Telford's name is familiar; his story less so. Born in 1757 in the Scottish Borders, his father died in his infancy, plunging the family into poverty. Telford's life soared to span almost eight decades of gloriously obsessive, prodigiously productive energy. Few people have done more to shape our nation.

A stonemason turned architect turned engineer, Telford invented the modern road, built churches, harbours, canals, docks, the famously vertiginous Pontcysyllte aqueduct in Wales and the dramatic Menai Bridge. His constructions were the greatest in Europe for a thousand years, and - astonishingly - almost everything he ever built remains in use today.

Intimate, expansive and drawing on contemporary accounts, Man of Iron is the first full modern biography of Telford. It is a book of roads and landscapes, waterways and bridges, but above all, of how one man transformed himself into the greatest engineer Britain has ever produced.

Moving, honest and inspiring - this is a nurse's true story of life in a busy A&E department during the Covid-19 crisis. Working in A&E is a challenging job but nurse Louise Curtis loves it. She was newly qualified as an advanced clinical practitioner, responsible for life or death decisions about the patients she saw, when the unthinkable happened and the country was hit by the Covid-19 pandemic. The stress on the NHS was huge and for the first time in her life, the job was going to take a toll on Louise herself. In A Nurse's Story she describes what happened next, as the trickle of Covid patients became a flood. And just as tragically, staff in A&E were faced with the effects of lockdown on society. They worried about their regulars, now missing, and saw an increase in domestic abuse victims and suicide attempts as loneliness hit people hard. By turns heartbreaking and heartwarming, this book shines a light on the compassion and dedication of hospital staff during such dark times. 'An important memoir that we all need to read right now.' - Closer

Ada, Countess of Lovelace (1815-1852), daughter of romantic poet Lord Byron and his highly educated wife, Anne Isabella, is sometimes called the world's first computer programmer and has become an icon for women in technology. But how did a young woman in the nineteenth century, without access to formal school or university education, acquire the knowledge and expertise to become a pioneer of computer science? Although an unusual pursuit for women at the time, Ada Lovelace studied science and mathematics from a young age. This book uses previously unpublished archival material to explore her precocious childhood, from her ideas for a steam-powered flying horse to penetrating questions about the science of rainbows. A remarkable correspondence course with the eminent mathematician Augustus De Morgan shows her developing into a gifted, perceptive and knowledgeable mathematician. Active in Victorian London's social and scientific elite alongside Mary Somerville, Michael Faraday and Charles Dickens, Ada Lovelace became fascinated by the computing machines devised by Charles Babbage. The table of mathematical formulae sometimes called the 'first programme' occurs in her paper about his most ambitious invention, his unbuilt 'Analytical Engine'. Ada Lovelace died at just thirty-six, but her paper still strikes a chord to this day, with clear explanations of the principles of computing, and broader ideas on computer music and artificial intelligence now realised in modern digital computers. Featuring images of the 'first programme' and Lovelace's correspondence, alongside mathematical models, and contemporary illustrations, this book shows how Ada Lovelace, with astonishing prescience, explored key mathematical questions to understand the principles behind modern computing.

A DAILY MAIL BOOK OF THE WEEK 'Spare Parts is a fascinating read filled with adventure, delight and surprise' RAHUL JANDIAL, surgeon author of 'Life on a Knife's Edge' 'This is a joyful romp through a fascinating slice of medical history' WENDY MOORE, author of 'The Knife Man' _______________________________________________________________ How did an architect help pioneer blood transfusion in the 1660s? Why did eighteenth-century dentists buy the live teeth of poor children? And what role did a sausage skin and an enamel bath play in making kidney transplants a reality? We think of transplant surgery as one of the medical wonders of the modern world. But transplant surgery is as ancient as the pyramids, with a history more surprising than we might expect. Paul Craddock takes us on a journey - from sixteenth-century skin grafting to contemporary stem cell transplants - uncovering stories of operations performed by unexpected people in unexpected places. Bringing together philosophy, science and cultural history, Spare Parts explores how transplant surgery constantly tested the boundaries between human, animal and machine, and continues to do so today. Witty, entertaining and at times delightfully macabre, Spare Parts shows us that the history - and future - of transplant surgery is tied up with questions about not only who we are, but also what we are, and what we might become. . .

Nnedi Okorafor was never supposed to be paralyzed. A college track star and budding entomologist, Nnedi's lifelong battle with scoliosis was just a bump in her plan - something a simple surgery would easily correct. But when Nnedi wakes from the surgery to find she can't move her legs, her entire sense of who she is begins to waver. Confined to a hospital bed for months, unusual things begin to happen. Psychedelic bugs crawl her hospital walls; strange dreams visit her nightly. She begins to feel as if she's turning into a cyborg. Unsure if she'll ever walk again, Nnedi begins to put these experiences into writing, conjuring up strange, fantastical stories. What Nnedi discovers during her confinement would prove to be the key to her life as a successful science fiction writer: In science fiction, when something breaks, something greater often emerges from the cracks. While she may be bedridden, instead of stopping her journey Nnedi's paralysis opens up new windows in her mind, kindles her creativity and ultimately leads her to become more alive than she ever could have imagined. Nnedi takes the reader on a journey from her hospital bed deep into her memories, from her painful first experiences with racism as a child in Chicago to her powerful visits to her parents' hometown in Nigeria, where she got her first inkling that science fiction has roots beyond the West. This was not the Africa that Nnedi knew from Western literature - an Africa that she always read was a place left behind. The role of technology in Nigeria opened her eyes to future-looking Africa: cable TV and cell phones in the village, 419 scammers occupying the cybercafes, the small generator connected to her cousin's desktop computer, everyone quickly adapting to portable tech devices due to unreliable power sources. Nnedi could see that Africa was far from broken, as she'd been taught, and her experience there planted the early seeds of sci-fi - a genre that speculates about technologies, societies, and social issues - from an entirely new lens. In Broken Places & Outer Spaces, Nnedi uses her own experience as a jumping off point to follow the phenomenon of creativity born from hardship. From Frida Kahlo to Mary Shelly, she examines great artists and writers who have pushed through their limitations, using hardship to fuel their work. Through these compelling stories and her own, Nnedi reveals a universal truth: What we perceive as limitations have the potential to become our greatest strengths - far greater than when we were unbroken.

Kenneth Allsop was a writer, journalist and broadcaster who in the 1960s and early 70s became one of Britain's first television celebrities. Voted the 'fifth most handsome man in the world', he enjoyed the high life of fast cars, jazz and smart London parties, moving among the nation's glitterati from the arts, media and politics. But he was also an accomplished naturalist and a passionate conservationist who fought fiercely to hold back mounting threats to Britain's wildlife and landscapes. He played a key role in raising the public's concern for the environment long before the advent of the UK's now-powerful green movement. Keeping the Barbarians at Bay focuses on the last few years of Allsop's short life, when he escaped London to live in a seventeenth- century watermill in the secret, crumpled landscape of West Dorset. The book describes how the threat of oil and gas exploration in this protected area of outstanding natural beauty forced him to become an environmental activist, and how his grassroots campaigning led him to the BBC's first environmentalist TV series Down to Earth, and to a radical 'green' column in The Sunday Times. Not surprisingly, he made powerful enemies in government and big business, at a time when there were few other environmental champions to lend him support. Using his unpublished diaries and papers, Keeping the Barbarians at Bay reveals the inside story of Allsop's struggles on three fronts: with 'the barbarians'; with the constant physical pain from his amputated right leg; and with his despair at the huge environmental challenges facing the planet. In the end, they were battles he could not win, and in May 1973 he took his own life at the tragically early age of 53.

ONE OF AMAZON'S TOP 100 BOOKS OF 2014 Neanderthal Man tells the story of geneticist Svante Paabo's mission to answer this question: what can we learn from the genomes of our closest evolutionary relatives? Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA. We learn that Neanderthal genes offer a unique window into the lives of our hominid relatives and may hold the key to unlocking the mystery of why humans survived while Neanderthals went extinct. Paabo's findings have not only redrawn our family tree, but recast the fundamentals of human history,the biological beginnings of fully modern Homo sapiens , the direct ancestors of all people alive today.

At a time when the Manhattan Project was synonymous with large-scale science, physicist J. Robert Oppenheimer (1904-67) represented the new sociocultural power of the American intellectual. Catapulted to fame as director of the Los Alamos atomic weapons laboratory, Oppenheimer occupied a key position in the compact between science and the state that developed out of World War II. By tracing the making--and unmaking--of Oppenheimer's wartime and postwar scientific identity, Charles Thorpe illustrates the struggles over the role of the scientist in relation to nuclear weapons, the state, and culture.
A stylish intellectual biography, "Oppenheimer" maps out changes in the roles of scientists and intellectuals in twentieth-century America, ultimately revealing transformations in Oppenheimer's persona that coincided with changing attitudes toward science in society.
"This is an outstandingly well-researched book, a pleasure to read and distinguished by the high quality of its observations and judgments. It will be of special interest to scholars of modern history, but non-specialist readers will enjoy the clarity that Thorpe brings to common misunderstandings about his subject."--Graham Farmelo," Times Higher Education Supplement""" "A fascinating new perspective. . . . Thorpe's book provides the best perspective yet for understanding Oppenheimer's Los Alamos years, which were critical, after all, not only to his life but, for better or worse, the history of mankind."--Catherine Westfall, "Nature"

'Beautiful . . . Justifies its place alongside nature writing classics such as H is for Hawk' NEW STATESMAN 'Wonderful ... both frank and fearless' TELEGRAPH BEST TRAVEL BOOKS OF THE YEAR 'Fascinating' GUARDIAN TOP TEN NATURE MEMOIRS From Mexico to the Arctic ice, grey whale mothers swim with their calves. Following them, by bus, train and ferry, are Doreen and her toddler Max, in pursuit of a wild hope. Doreen first visited Alaska as a young journalist reporting on climate change among indigenous whaling communities. There, drawn deeply into an Inupiaq family, she joined the bowhead whale hunt, watching for polar bears under the never-ending light. Years later, now a single mother living in a hostel, Doreen embarks on this extraordinary journey: following the grey whale migration back to the Arctic, where greys and bowheads meet at the melting apex of our planet. 'Soundings got under my skin. I finished it in tears' AMY LIPTROT 'What a voice! What a book!' CHARLES FOSTER 'Soulful, honest, insightful, humane and propulsive' JINI REDDY 'Thrilling, passionate and tender-hearted' HELEN JUKES WINNER OF THE RSL GILES ST AUBYN AWARD ONE OF SMITHSONIAN MAGAZINE'S TEN BEST BOOKS ABOUT TRAVEL OF 2022

Louis Bromfield was a World War I ambulance driver, a Paris expat, and a Pulitzer Prize-winning novelist as famous in the 1920s as Hemingway or Fitzgerald. But he cashed in his literary success to finance a wild agrarian dream in his native Ohio. The ideas he planted at his utopian experimental farm, Malabar, would inspire America's first generation of organic farmers and popularize the tenets of environmentalism years before Rachel Carson's Silent Spring. A lanky Midwestern farm boy dressed up like a Left Bank bohemian, Bromfield stood out in literary Paris for his lavish hospitality and his green thumb. He built a magnificent garden outside the city where he entertained aristocrats, movie stars, flower breeders, and writers of all stripes. Gertrude Stein enjoyed his food, Edith Wharton admired his roses, Ernest Hemingway boiled with jealousy over his critical acclaim. Millions savored his novels, which were turned into Broadway plays and Hollywood blockbusters, yet Bromfield's greatest passion was the soil. In 1938, Bromfield returned to Ohio to transform 600 badly eroded acres into a thriving cooperative farm, which became a mecca for agricultural pioneers and a country retreat for celebrities like Humphrey Bogart and Lauren Bacall (who were married there in 1945). This sweeping biography unearths a lost icon of American culture, a fascinating, hilarious and unclassifiable character who-between writing and plowing-also dabbled in global politics and high society. Through it all, he fought for an agriculture that would enrich the soil and protect the planet. While Bromfield's name has faded into obscurity, his mission seems more critical today than ever before.

God of Sperm tells the remarkable story of Dr. Cappy Miles Rothman, the son of notorious gangster Norman "Roughhouse" Rothman, who went on to become a trailblazer in the field of reproductive medicine. Rothman started the California Cryobank, one of the world's largest repositories of reproductive genetic material and cord-blood stem cells. Among other achievements, Rothman also pioneered the use of microsurgery in urological procedures, postmortem sperm retrieval techniques, and was one of the first practitioners of andrology, a specialty dealing with male reproductive biology and medicine. How Cappy Rothman went from Mafia scion and man-about-town during the postwar Miami Beach--Havana era of gangster chic to one of the most consequential figures in modern medicine is an epic, only-in-America tale that is also a fine reminder of the broad horizons and wild possibilities life in the U.S. can offer.

Rudolph Glossop made a unique contribution to the early development of both geotechnical engineering and engineering geology and this volume presents a fascinating and revealing perspective on his involvement by means of selected extracts from personal diaries, letters and journals. From his early experience as an undergraduate and the four years spent in the Gold Coast to the establishment of Soil Mechanics Ltd and his time as director of Mowlems, Glossop became one of the key figures and was involved in many of the key stages in the development of geotechnology. His journal provides a fuller understanding of the Mulberry Harbour, which was a key factor in the success of the D-Day landings in northern France, June 1944; while his diaries give a unique account of the significant challenges that had to be overcome during construction of Derwent Dam, N.E. England.The famous Skempton, in his obituary of Glossop, refers to works of original scholarship, written with the clarity and style of which Glossop was a master - by his own example and by the example of others, he never lost sight of the importance of bringing together the practical and academic aspects of both geology and soil mechanics. A" Ron Williams has painstakingly pieced together a fascinating account of the life and career of an outstanding engineer, and in the process has painted a vivid portrait of Rudolph Glossop and his achievements. Not before time will today's engineers and scientists have the opportunity to appreciate the achievements of one of the key figures in geotechnical engineering.

As command module pilot of Apollo 17, the last crewed flight to the moon, Ron Evans combined precision flying and painstaking geological observation with moments of delight and enthusiasm. On his way to the launchpad, he literally jumped for joy in his spacesuit. Emerging from the command module to conduct his crucial spacewalk, he exclaimed, "Hot diggity dog!" and waved a greeting to his family. As a patriotic American in charge of command module America, Evans was nicknamed "Captain America" by his fellow crew members. Born in 1933 in St. Francis, Kansas, Evans distinguished himself academically and athletically in school, earned degrees in electrical engineering and aeronautical engineering, and became a naval aviator and a combat flight instructor. He was one of the few astronauts who served in combat during the Vietnam War, flying more than a hundred missions off the deck of the USS Ticonderoga, the same aircraft carrier that would recover him and his fellow astronauts after the splashdown of Apollo 17. Evans's astronaut career spans the Apollo missions and beyond. He served on the support crews for 1, 7, and 11 and on the Apollo 14 backup crew before being selected for Apollo 17 and flying on the final moon mission in 1972. He next trained with Soviet cosmonauts as backup command module pilot for the 1975 Apollo-Soyuz mission and carried out early work on the space shuttle program. Evans then left NASA to pursue a business career. He died suddenly in 1990 at the age of fifty-six.

A brilliantly witty book about the intertwined lives of psychoanalyst Ernest Jones, surgeon Wilfred Trotter and the guru of psychoanalysis, Sigmund Freud. Ernest Jones was Sigmund Freud's closest associate and most fervent disciple. Clever, self-confident and intensely ambitious, Jones promoted psychoanalysis as a kind of secular religion. It was also an escape for him from a medical career blighted by repeated allegations of sexual abuse. Meanwhile, his intimate friend and brotherin-law Wilfred Trotter - a celebrated surgeon who dramatically saved the life of George V, and who took on Freud as a patient during his London exile - refused to yield to the seductions of the new Freudianism. A quintessentially English figure, Trotter was unimpressed by slick medical careerists, distrusted grand theories and lacked pomposity and self-regard. From the early beginnings of psychoanalysis to the illness of King George in 1928 and the final meeting of Freud and Trotter in 1939, Seamus O'Mahony tells the story of these three figures and their lives with lapidary wit and erudition. This is a book about cultish belief, healthy scepticism and the sexual obsessions of intellectual and bohemian circles in London, Cambridge and Vienna, and doctors in pursuit of wealth and fame. It brings to life a pivotal moment in modern cultural history and reflects on how and why the writings of a failed neurologist from Vienna became so influential.

'Delightfully insightful and intensely readable [...] There is an energy and drama to Rory's writing which nonetheless leaves space for us, the reader, to make up our minds' - Stephen Fry We live at a time when billions have access to unbelievably powerful technology. The most extraordinary tool that has been invented in the last century, the smartphone, is forcing radical changes in the way we live and work - and unlike previous technologies it is in the hands of just about everyone. Coupled with the rise of social media, this has ushered in a new era of deeply personal technology, where individuals now have the ability to work, create and communicate on their own terms, rather than wait for permission from giant corporations or governments. At least that is the optimistic view. This book takes readers on an entertaining ride through this turbulent era, as related by an author with a ringside seat to the key moments of the technology revolution. We remember the excitement and wonder that came with the arrival of Apple's iPhone with all the promise it offered. We see tech empires rise and fall as these devices send shockwaves through every industry and leave the corporate titans of the analogue era floundering in their wake. We see that early utopianism about the potential of the mobile social revolution to transform society for the better fade, as criminals, bullies and predators poison the well of social media. And we hear from those at the forefront of the tech revolution, including Stephen Hawking, Elon Musk, Tim Berners-Lee, Martha Lane-Fox and Jimmy Wales, to gain their unique insights and predictions for what may be to come. Always On immerses the reader in the most important story of our times - the dramatic impact of hyperconnectivity, the smartphone and social media on everything from our democracy to our employment and our health. The final section of the book draws on the author's own personal experience with technology and medicine, considering how COVID-19 made us look again to computing in our battle to confront the greatest challenge of modern times.

In 2017, Dr Suzanne Koven published an essay describing the challenges faced by women doctors, including her own personal struggle with "imposter syndrome"-a long-held, secret belief that she was not clever enough or good enough to be a "real" doctor. Accessed nearly 300,000 times by readers around the world, Koven's Letter to a Young Female Physician has evolved into a work that reflects on her career in medicine, in which women still encounter sexism, pay inequity and harassment. Koven tells engaging stories about her pregnancy during a gruelling residency in the AIDS era; the illnesses of her son and parents during which her roles as a doctor, mother and daughter converged; and the twilight of her career during the COVID-19 pandemic. Letter to a Young Female Physician offers an indelible eyewitness account from a doctor, mother, wife, daughter, teacher and writer that will encourage readers to embrace their own imperfect selves.