The heart-wrenchingly honest and fascinating new book from forensic pathologist and bestselling author of UNNATURAL CAUSES, Dr Richard Shepherd A TIMES AND SUNDAY TIMES BOOK OF THE YEAR 'Each chapter is like a finely-crafted detective story . . . Shepherd writes beautifully, and despite its subject, the book is very funny in parts' DAILY TELEGRAPH 'Enlightening, strangely uplifting . . . Shepherd's final chapter on death itself is a meditation of great beauty and light which puts all the darkness of the previous pages into perspective' DAILY MAIL 'Deeply insightful. Unflinching' THE TIMES 'Fascinating' DAILY EXPRESS 'This book is about death, but in it I will take readers on a journey through life . . .' _________ Dr Richard Shepherd, Britain's top forensic pathologist, has spent a lifetime close to the dead. As a medical detective, each autopsy he carries out is its own unique investigation, uncovering the secrets not only of how a person died, but also of how they lived. Through twenty-four of his most intriguing, enlightening and never-before-told cases, Dr Shepherd shares autopsies that span the seven ages of human existence, and have taught him as much about the marvels of life as the inevitability of death. From old to young, from murder to misadventure, and from illness to accidental death, each of these bodies has something to reveal: about human development, about mortality, about its owner's life story, about justice and even about Shepherd himself. From the bestselling author of Unnatural Causes comes a powerful, moving and above all reassuring book about death as it touches our own lives - how to understand it, and, when our time comes (as it must), how to embrace it as the last great adventure. _________ 'He has the ability to examine himself and other people with the same forensic eye that he applies to corpses - one of the reasons why his books feel so life-enhancing' Daily Telegraph Praise for Dr Richard Shepherd 'Gripping, grimly fascinating, and I suspect I'll read it at least twice' Evening Standard 'A deeply mesmerising memoir of forensic pathology. Human and fascinating' Nigella Lawson 'An absolutely brilliant book. I really recommend it, I don't often say that but it's fascinating' Jeremy Vine, BBC Radio 2 'Puts the reader at his elbow as he wields the scalpel' Guardian 'Fascinating, gruesome yet engrossing' Richard and Judy, Daily Express 'Fascinating, insightful, candid, compassionate' Observer

THE NO. 1 SUNDAY TIMES BESTSELLER This is Going to Hurt was the publishing phenomenon of the century, read by many millions, loved by at least fifty of them, and adapted into a major TV series. But it was only part of the story. By turns hilarious, heartbreaking and humbling, Undoctored is about what happens when a doctor hangs up his scrubs, but medicine refuses to let go of him. It's about an extraordinary medical school education. It's about opening old wounds and examining the present-day scars. It's about hospital admissions and personal ones. It's about blowing up your life and stitching it back together. It's about being a doctor and being a patient. It's about 300 pages long. Undoctored is Adam Kay's funniest and most moving book yet - an astonishing portrait of a life in and out of medicine, from one of Britain's finest storytellers.

Families are riddled with untold secrets. But Stephen Hinshaw never imagined that a profound secret was kept under lock and key for 18 years within his family - that his father's mysterious absences, for months at a time, resulted from serious mental illness and involuntary hospitalisations. From the moment his father revealed the truth, during Hinshaw's first spring break from college, he knew his life would change forever. Hinshaw calls this revelation his 'psychological birth.' After years of experiencing the ups and downs of his father's illness without knowing it existed, Hinshaw began to piece together the silent, often terrifying history of his father's life - in great contrast to his father's presence and love during periods of wellness. This exploration led to larger discoveries about the family saga, to Hinshaw's correctly diagnosing his father with bipolar disorder, and to his full-fledged career as a clinical and developmental psychologist and professor. In Another Kind of Madness, Hinshaw explores the burden of living in a family 'loaded' with mental illness and debunks the stigma behind it. He explains that in today's society, mental health problems still receive utter castigation - too often resulting in the loss of fundamental rights, including the inability to vote or run for office or automatic relinquishment of child custody. Through a poignant and moving family narrative, interlaced with shocking facts about how America and the world still view mental health conditions well into in the 21st century, Another Kind of Madness is a passionate call to arms regarding the importance of destigmatising mental illness.

The long-awaited memoir of a trailblazer and role model who is telling her story for the first time. Eileen Collins was an aviation pioneer her entire career, from her crowning achievements as the first woman to command an American space mission as well as the first to pilot the space shuttle to her early years as one of the Air Force's first female pilots. She was in the first class of women to earn pilot's wings at Vance Air Force Base and was their first female instructor pilot. She was only the second woman admitted to the Air Force's elite Test Pilot Program at Edwards Air Force Base. NASA had such confidence in her skills as a leader and pilot that she was entrusted to command the first shuttle mission after the Columbia disaster, returning the US to spaceflight after a two-year hiatus. Since retiring from the Air Force and NASA, she has served on numerous corporate boards and is an inspirational speaker about space exploration and leadership. Eileen Collins is among the most recognized and admired women in the world, yet this is the first time she has told her story in a book. It is a story not only of achievement and overcoming obstacles but of profound personal transformation. The shy, quiet child of an alcoholic father and struggling single mother, who grew up in modest circumstances and was an unremarkable student, she had few prospects when she graduated from high school, but she changed her life to pursue her secret dream of becoming an astronaut. She shares her leadership and life lessons throughout the book with the aim of inspiring and passing on her legacy to a new generation.

'Indecently entertaining.' A Daily Mail Book of the Week An Amazon US Best Book of 2022 'A fascinating tale of poisons and poisonous deeds which both educates and entertains.' - Kathy Reichs As any reader of murder mysteries can tell you, poison is one of the most enduring - and popular - weapons of choice for a scheming murderer. It can be slipped into a drink, smeared onto the tip of an arrow or the handle of a door, even filtered through the air we breathe. But how exactly do these poisons work to break our bodies down, and what can we learn from the damage they inflict? In a fascinating blend of popular science, medical history, and narrative crime nonfiction, Dr Neil Bradbury explores this most morbidly captivating method of murder from a cellular level. Alongside real-life accounts of murderers and their crimes -some notorious, some forgotten, some still unsolved - are the equally compelling stories of the poisons involved: eleven molecules of death that work their way through the human body and, paradoxically, illuminate the way in which our bodies function. Drawn from historical records and current news headlines, A Taste for Poison weaves together the fascinating tales of spurned lovers, shady scientists, medical professionals and political assassins, showing how the precise systems of the body can be impaired to lethal effect through the use of poison. From the deadly origins of the gin & tonic cocktail to the arsenic-laced wallpaper in Napoleon's bedroom, A Taste for Poison leads readers on a fascinating tour of the intricate, complex systems that keep us alive - or don't.

Learn about the boy who - could read and add numbers when he was three years old, - thwarted his teacher by finding a quick and easy way to sum the numbers 1-100, - attracted the attention of a Duke with his genius, and became the man who... - predicted the reappearance of a lost planet, - discovered basic properties of magnetic forces, - invented a surveying tool used by professionals until the invention of lasers. Based on extensive research of original and secondary sources, this historical narrative will inspire young readers and even curious adults with its touching story of personal achievement.

With an introduction by author of The Tidal Zone, Sarah Moss

The Immortal Life of Henrietta Lacks is the true story behind the HBO film starring Oprah Winfrey and Rose Byrne.

Her name was Henrietta Lacks, but scientists know her as HeLa. Born a poor black tobacco farmer, her cancer cells – taken without her knowledge – became a multimillion-dollar industry and one of the most important tools in medicine. Yet Henrietta’s family did not learn of her ‘immortality’ until more than twenty years after her death, with devastating consequences . . .

Rebecca Skloot’s fascinating account is the story of the life, and afterlife, of one woman who changed the medical world for ever. Balancing the beauty and drama of scientific discovery with dark questions about who owns the stuff our bodies are made of, The Immortal Life of Henrietta Lacks is an extraordinary journey in search of the soul and story of a real woman, whose cells live on today in all four corners of the world.

Prepare to be intrigued, amazed and astonished as you join Dr Rhona Morrison on an often funny, and at times downright bizarre, thought-provoking and eye-opening rollercoaster ride through some of the most curious encounters of her career as a leading forensic psychiatrist.Delve into the minds of real people, whose actions may shock and stun you, but who's stories have the power to challenge your assumptions and the stigma that surrounds mental illness.Travel directly into their living rooms and see behind the closed doors of hospitals, prisons and court rooms. Lift the lid on Dr Morrison's jaw-dropping experiences with murderers, stalkers and other dangerous offenders as she attempts to make sense of some highly unusual situations. Discover the true stories of the inspiring human beings who are bravely learning to live with major mental illness.'I don't talk to dead bodies' shines a powerful, emotional and surprisingly moving spotlight on the fascinating life of a forensic psychiatrist and the people she works with. It goes beyond the sensationalist headlines to show you just what happens in a world where mental illness occasionally makes good people do bad things.

A "beautifully written" (Kirkus Reviews, starred review) memoir-manifesto from the first female director of the National Science Foundation about the entrenched sexism in science, the elaborate detours women have take to bypass the problem, and how to fix the system. If you think sexism thrives only on Wall Street or Hollywood, you haven't visited a lab, a science department, a research foundation, or a biotech firm. Rita Colwell is one of the top scientists in America: the groundbreaking microbiologist who discovered how cholera survives between epidemics and the former head of the National Science Foundation. But when she first applied for a graduate fellowship in bacteriology, she was told, "We don't waste fellowships on women." A lack of support from some male superiors would lead her to change her area of study six times before completing her PhD. A Lab of One's Own is an "engaging" (Booklist) book that documents all Colwell has seen and heard over her six decades in science, from sexual harassment in the lab to obscure systems blocking women from leading professional organizations or publishing their work. Along the way, she encounters other women pushing back against the status quo, including a group at MIT who revolt when they discover their labs are a fraction of the size of their male colleagues. Resistance gave female scientists special gifts: forced to change specialties so many times, they came to see things in a more interdisciplinary way, which turned out to be key to making new discoveries in the 20th and 21st centuries. Colwell would also witness the advances that could be made when men and women worked together--often under her direction, such as when she headed a team that helped to uncover the source of anthrax used in the 2001 letter attacks. A Lab of One's Own is "an inspiring read for women embarking on a career or experiencing career challenges" (Library Journal, starred review) that shares the sheer joy a scientist feels when moving toward a breakthrough, and the thrill of uncovering a whole new generation of female pioneers. It is the science book for the #MeToo era, offering an astute diagnosis of how to fix the problem of sexism in science--and a celebration of women pushing back.

George Stephenson is among the most famous engineers of all time. His rise from 'rags to riches' is a stirring story of its kind, but many of the works attributed to him should in fact be credited to young subordinates, not least his son, Robert. But much of the work of innovative engineers for his period lay not in the work itself but in persuading people that such work was desirable and necessary. It was in this field that George Stephenson excelled, providing openings in which his young proteges could change the world. They did not let him down, and we should give him full credit for being 'The Father of the Railways'. Adrian Jarvis specialises in the engineering and finance of dock and harbour construction, on which he has published extensively, but he also has a strong interest in early railways and in the general history of technology. Another book for Shire by this author is: The Victorian Engineer

THE NO. 1 NEW YORK TIMES BESTSELLER, NOW A MAJOR NEW NETFLIX SERIES 'Reminds us that the mind is the greatest mystery in the universe' Yuval Noah Harari, Guardian, Books of the Year Could psychedelic drugs change our worldview? Join Michael Pollan on a journey to the frontiers of the human mind. Diving deep into an extraordinary world - from shamans and magic mushroom hunts to the pioneering labs mapping our brains - and putting himself forward as a guinea-pig, Michael Pollan has written a remarkable history of psychedelics and a compelling portrait of the new generation of scientists fascinated by the implications of these drugs. How to Change Your Mind is a report from what could very well be the future of consciousness. 'A sweeping and often thrilling chronicle of the history of psychedelics, all interwoven with Pollan's adventures as a psychedelic novice. This is a serious work of history and science, but also one in which the author, under the influence of toad venom, becomes convinced he's giving birth to himself' Oliver Burkeman, Guardian 'A mind-altering book ... full of transformations' Richard Godwin, Evening Standard 'An irresistible blend of history, research and personal experience. In terms of the psychedelic wave, the book is the big kahuna, the Big Bang moment for a movement that is gathering force' John McKenna, Irish Times 'Entertaining and engrossing' Paul Laity, Financial Times 'Deeply absorbing, wise and beautifully written' Mick Brown, Literary Review 'An astounding book' Andrew Sullivan, New York Magazine

A TIME magazine Must-Read Book of the Year Ever wonder what your therapist is thinking? Now you can find out, as therapist and New York Times bestselling author Lori Gottlieb takes us behind the scenes of her practice - where her patients are looking for answers (and so is she). When a personal crisis causes her world to come crashing down, Lori Gottlieb - an experienced therapist with a thriving practice in Los Angeles - is suddenly adrift. Enter Wendell, himself a veteran therapist with an unconventional style, whose sessions with Gottlieb will prove transformative for her. As Gottlieb explores the inner chambers of her own patients' lives - a self-absorbed Hollywood producer, a young newlywed diagnosed with a terminal illness, a senior citizen who feels she has nothing to live for, and a self-destructive twenty-something who can't stop hooking up with the wrong guys - she finds that the questions they are struggling with are the very questions she is bringing to Wendell. Taking place over one year, and beginning with the devastating event that lands her in Wendell's office, Maybe You Should Talk to Someone offers a rare and candid insight into a profession that is conventionally bound with rules and secrecy. Told with charm and compassion, vulnerability and humour, it's also the story of an incredible relationship between two therapists, and a disarmingly funny and illuminating account of our own mysterious inner lives, as well as our power to transform them.

Discovering the passions of Chris Woodhead Collected writings from a man who stimulated controversy and roused passions Best known as the Chief Inspector of Schools who demanded higher standards across the board, Woodhead was admired and condemned in equal measure for his determination to confront taboos and bring them into the national education debate. His final and greatest challenge was with Motor Neurone Disease, a condition he faced with strength and empathy until his death in 2015. While his education journalism stands at the core of this book, What Matters Most explores Woodhead's lesser known passions, literature and climbing, which he writes about with the precision and clarity that became his journalistic hallmark. In the final pages of the book Woodhead shares his personal views on assisted dying, advocating for individuals to be permitted to die with dignity at a time of their choosing. What Matters Most: A Collection of Pieces is a fascinating and poignant book which tracks the life and beliefs of a truly inspirational contemporary thinker.

'Charming and addictively accessible' STEVEN PINKER 'Original, authoritative and beautiful' BRIAN COX 'The most wonderful adventure' ROBIN INCE A brilliantly illustrated journey through the wonders and mysteries of the human brain - from a renowned husband-and-wife team of cognitive neuroscientists. Professors and husband-and-wife team Uta and Chris Frith have pioneered major studies of brain disorders throughout their nearly fifty-year career. In Two Heads, their distinguished careers serve as a prism through which they share the compelling story of the birth of neuroscience and their paradigm-shifting discoveries across areas as wide-ranging as autism and schizophrenia research, and new frontiers of social cognition including diversity, prejudice, confidence, collaboration and empathy. Working with their son Alex Frith and artist Daniel Locke, they examine the way that neuroscientific research is now focused on the fact we are a social species, whose brains have evolved to work cooperatively. What happens when people gather in groups? How do people behave when they're in pairs - either pitted against each other or working together? Is it better to surround yourself with people who are similar to yourself, or different? And, are two heads really better than one? Highly original and ingeniously illustrated, Two Heads provides an expansive understanding of how our brains work, and how they work together.

Charles Darwin has become one of the most important men in history. The quiet, unsure polymath who avoided confrontation, ensconced in his family home at Down House in Kent, was also a revolutionary who developed his idea of Natural Selection in isolation. Cyril Aydon's short biography is considered one of the best introductions to the life and ideas of Darwin. With Darwin's legacy still in contention and the forthcoming anniversary of the publication of "The Origins Species", Aydon's book is a perfect guide to the ideas as well as the man who was recently voted one of the greatest Britons of all time, and certainly one of the most influential thinkers ever.

Just two months before the September 11 terrorist attacks, Dr. Judy Melinek began her training as a New York City forensic pathologist. While her husband and their toddler held down the home front, Judy threw herself into the fascinating world of death investigation-performing autopsies, investigating death scenes, counseling grieving relatives. Working Stiff chronicles Judy's two years of training, taking readers behind the police tape of some of the most harrowing deaths in the Big Apple, including a firsthand account of the events of September 11, the subsequent anthrax bio-terrorism attack, and the disastrous crash of American Airlines Flight 587. An unvarnished portrait of the daily life of medical examiners-complete with grisly anecdotes, chilling crime scenes, and a welcome dose of gallows humor-Working Stiffoffers a glimpse into the daily life of one of America's most arduous professions, and the unexpected challenges of shuttling between the domains of the living and the dead. The body never lies-and through the murders, accidents, and suicides that land on her table, Dr. Melinek lays bare the truth behind the glamorized depictions of autopsy work on television to reveal the secret story of the real morgue. "Haunting and illuminating...the stories from her average workdays...transfix the reader with their demonstration that medical science can diagnose and console long after the heartbeat stops" (The New York Times).

Discover one of the Scottish Enlightenment's brightest stars. Among the giants of the Scottish Enlightenment, the name of James Hutton is overlooked. Yet his Theory of the Earth revolutionised the way we think about how our planet was formed and laid the foundation for the science of geology. He was in his time a doctor, a farmer, a businessman, a chemist yet he described himself as a philosopher - a seeker after truth. A friend of James Watt and of Adam Smith, he was a polymath, publishing papers on subjects as diverse as why it rains and a theory of language. He shunned status and official position, refused to give up his strong Scots accent and vulgar speech, loved jokes and could start a party in an empty room. Yet much of his story remains a mystery. His papers, library and mineral collection all vanished after his death and only a handful of letters survive. He seemed to be a lifelong bachelor, yet had a secret son whom he supported throughout his life. This book uses new sources and original documents to bring Hutton the man to life and places him firmly among the geniuses of his time.

Soon to be a major motion picture, the story of one of the most improbable and productive collaborations ever chronicled, between a young unschooled Indian prodigy and a great English mathematician.

In 1913, a young unschooled Indian clerk wrote a letter to G H Hardy, begging the preeminent English mathematician's opinion on several ideas he had about numbers. Realizing the letter was the work of a genius, Hardy arranged for Srinivasa Ramanujan to come to England. Thus began one of the most improbable and productive collaborations ever chronicled. With a passion for rich and evocative detail, Robert Kanigel takes us from the temples and slums of Madras to the courts and chapels of Cambridge University, where the devout Hindu Ramanujan, "the Prince of Intuition," tested his brilliant theories alongside the sophisticated and eccentric Hardy, "the Apostle of Proof." In time, Ramanujan's creative intensity took its toll: he died at the age of thirty-two and left behind a magical and inspired legacy that is still being plumbed for its secrets today.

'A remarkably honest memoir of a life spent pulling people back from death' - Adam Kay In these stories, Dr Jim Down brings us to the very heart of the intensive care unit - the section of the hospital where the sickest patients are brought to be cared for until their condition improves. With honesty, humility and a streak of dark humour, Dr Down describes the quietly heroic work of doctors and nurses on the ICU, a place which sits at the cutting edge of medical technology and where a split-second decision can make the difference between life and death. From headline-grabbing cases like that of Alexander Litvinenko, poisoned by Russian agents and admitted to Down's ward, to the appalling aftermath of a train crash, Life in the Balance offers an inside glimpse of intensive care medicine, its immense challenges, deleterious effects on doctors' mental health and enormous rewards. Its profundity will make you reconsider the fragility of life and reframe your understanding of what it means to care.