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Books > Medicine > Surgery > Transplant surgery
The sudden call, the race to the hospital, the high-stakes operation - the drama of transplant surgery is well known. But what happens before and after the surgery? In Transplanting Care, Laura L. Heinemann examines the daily lives of midwestern organ transplant patients and those who care for them, from pretransplant preparations through to the long posttransplant recovery. Heinemann points out that as efforts to control healthcare costs gain urgency - and as new surgical techniques, drug therapies, and home medical equipment advance - most of the transplant process now takes place at home, among kin. Indeed, the transplant system effectively depends on unpaid care labor, typically provided by spouses, parents, siblings, and others. Drawing on scores of interviews with patients, relatives, and healthcare professionals, Heinemann follows a variety of patients and loved ones as they undertake this uncertain and strenuous ""transplant journey."" She also shows how these home-based caregiving efforts take place within the larger economic and political context of a paucity of resources for patients and caregivers, who ultimately must surmount numerous obstacles. The author concludes that the many snags encountered by transplant patients and loved ones make a clear case for more comprehensive health and social policy that treats care as a necessarily shared public responsibility. An illuminating look at the long transplant journey, Transplanting Care also offers broader insight into how we handle infirmity in America - and how we might do a better job of doing so.
Organ transplantation has revolutionized the treatment for end-stage organ failure. Immunosuppression is still a major approach currently used in the prevention and treatment of allograft rejection. Both editors Dr. Chen and Dr. Qian have been contributing to preclinical evaluation of immunosuppressants for more than 25 years in North America. Experts from the United States, Canada, the United Kingdom, China, Japan, Germany, Sweden, Hungary and Brazil contributed 23 chapters to this book, providing details of immunological basis in transplantation. They also describe six classes of immunosuppressive agents (calcineurin inhibitors, mTOR inhibitors, JAK-STAT inhibitors, antiproliferative agents, costimulation blockers and corticosteroids), as well as ischemia/reperfusion injury treated agents. Additionally, the new development of cell therapy in the induction of transplant tolerance is introduced. This book provides many important references for the research direction of novel immunosuppressants. Readers that will find this book useful include transplant physicians, surgeons, nurses, immunologists, pharmacologists, pharmacists, medical students, residents and trainees in transplantation.
Hair Transplant 360: Volume 4 – Follicular Unit Extraction (FUE) is an illustrated guide to this minimally invasive procedure, involving the grafting of hair follicles that are genetically resistant to balding, onto a bald scalp. This book is edited by Samuel Lam, Director of the Lam Institute for Hair Restoration, Texas, and Kenneth L Williams from the Irvine Institute of Medicine and Cosmetic Surgery/Orange County Hair Restoration, California. The book is divided into 25 chapters across three sections. The first section covers the basics of FUE beginning with the history, terminology and physics of the technique. Other chapters include information on skin properties and anatomy, scalp anaesthesia, donor evaluation and surgical planning, and improving graft survival. Guidance on starting a practice in FUE is also included. The second part of the book covers FUE methods in detail, and the final section features discussion on specialised topics, such as regenerative medicine, complications and difficulties of FUE, and FUE from the beard and body. Hair Transplant 360: Volume 4 – Follicular Unit Extraction (FUE) contains 510 full colour photographs and illustrations, and includes four DVD ROMs demonstrating various FUE procedures in detail. Key Points Comprehensive, illustrated guide to follicular unit extraction procedures Edited by renowned US experts in the field 510 full colour photographs and illustrations Includes four DVD ROMs demonstrating FUE procedures
This is a completely revised and expanded edition of Hair Transplant 360 for Assistants, Volume 2, edited by Emina Karamovski Vance from the Lam Institute for Hair Restoration in Plano, Texas. The book is divided into two parts: the first part, ‘Core 360’, covers the basics of hair anatomy, growth cycles necessary for assisting hair restoration, male and female pattern baldness, non-surgical hair loss solutions, and the evolution of hair restoration procedures. Part one also features extensive sections on graft preparation and graft placement. The second part of the book, ‘More 360’, covers patient care, from postoperative through short and long term follow-up. Part two features an assistant training section which includes standardised hair-transplant photography and stress management. This highly illustrated new edition also includes an expanded and updated DVD-ROM covering a wide range of topics, from surgery overview and preparation, to quality control, graft handling and placement, and a ‘Test Your Knowledge’ section, making Hair Transplant 360 for Assistants, Volume 2 an ideal resource for hair transplant assistants in training. Key Points Completely revised and expanded edition Previous edition published 2011 (9789350251799) DVD-ROM featuring surgery overview, assistant training, and ‘Test Your Knowledge’ section 319 colour images and illustrations Edited by Emina Karamanovski Vance from Lam Institute for Hair Restoration, Plano, Texas
This is a completely revised and expanded edition of Hair Transplant 360 for Physicians, Volume 1, edited by Samuel M Lam, Director of the Lam Institute for Hair Restoration Plano, Texas, featuring extensive discussion of bioenhancement technology. The book is divided into two parts: part one focuses on preoperative, operative and postoperative care. Chapter one features brand new and updated information on several therapies, and discussion on medical hair loss conditions. Chapter two includes completely revised guidance on operative technique, with a range of step-by-step techniques including hairline design, donor harvesting and recipient-site creation. The post-operative chapter includes discussion on creating standardised hair-transplant photography, leadership, office management and marketing. The second part of the book contains new case studies in hair transplantation, and a final chapter on physician training, which is demonstrated on a DVD-ROM. The DVD has been expanded and updated to cover hairline design using human models, donor harvesting, and recipient-site practice, making Hair Transplant 360 for Physicians, Volume 1 an ideal resource for hair transplant physicians in training. Key Points Revised and expanded second edition Previous edition published 2011 (9789350251782) 263 full colour images and illustrations DVD-ROM including step-by-step demonstrations for trainee physicians Edited by Samuel M Lam, Director, Lam Institute for Hair Restoration Plano, Texas, USA
In his late 40s, Steve Burcham suddenly experienced inexplicable heart failure. The struggle to survive and finally get a heart transplant changed more than his physical health and well-being. How he managed to keep going through it all makes for an uplifting story of medical miracles and spiritual healing filled with humor, determination, prayer and ultimately unshakeable faith.
This unique volume may very well foreshadow the treatment of renal disease in the twenty-first century. The editors have obviously compiled and reviewed the current clinical problems in which the kidney plays a major role. They then selected as topics for chapters those in which recent scientific investigations have added significant new data. The investigators themselves or their peers have been persuaded to produce a summary of current concepts of renal structure and function for each topic. The result is a volume which will be as invaluable as a clinical guide on the laboratory bench as it will be a reference for the clinician seeking guidance to rational therapy at the bedside. The strength of the volume lies in the incorporation of those data on renal cellular structure and function which hold the key to the etiology of the majority of renal diseases we now call 'end-stage'. Fully, two-thirds of the volume is devoted to current concepts of renal function and related subcellular structure of various renal tissues. The illustrations, correlations, and explanations are superbly presented in much detail and with an obvious effort to fill out the current knowledge of each subject. We may anticipate this book will remain a valuable reference for many years to come.
In February 2003, an undocumented immigrant teen from Mexico lay dying in a prominent American hospital due to a stunning medical oversight - she had received a heart-lung transplantation of the wrong blood type. In the following weeks, Jesica Santillan's tragedy became a portal into the complexities of American medicine, prompting contentious debate about new patterns and old problems in immigration, the hidden epidemic of medical error, the lines separating transplant ""haves"" from ""have-nots,"" the right to sue, and the challenges posed by ""foreigners"" crossing borders for medical care. This volume draws together experts in history, sociology, medical ethics, communication and immigration studies, transplant surgery, anthropology, and health law to understand the dramatic events, the major players, and the core issues at stake. Contributors view the Santillan story as a morality tale: about the conflicting values underpinning American health care; about the politics of transplant medicine; about how a nation debates deservedness, justice, and second chances; and about the global dilemmas of medical tourism and citizenship.
Foreword by Clyde Barker and Thomas E. Starzl A History of Organ Transplantation is a comprehensive and ambitious exploration of transplant surgery -- which, surprisingly, is one of the longest continuous medical endeavors in history. Moreover, no other medical enterprise has had so many multiple interactions with other fields, including biology, ethics, law, government, and technology. Exploring the medical, scientific, and surgical events that led to modern transplant techniques, Hamilton argues that progress in successful transplantation required a unique combination of multiple methods, bold surgical empiricism, and major immunological insights in order for surgeons to develop an understanding of the body's most complex and mysterious mechanisms. Surgical progress was nonlinear, sometimes reverting and sometimes significantly advancing through luck, serendipity, or helpful accidents of nature. The first book of its kind, A History of Organ Transplantation examines the evolution of surgical tissue replacement from classical times to the medieval period to the present day. This well-executed volume will be useful to undergraduates, graduate students, scholars, surgeons, and the general public. Both Western and non-Western experiences as well as folk practices are included.
This book presents international experimental and clinical experience on limb transplantation and other composite tissue allografts, representing the most complete and comprehensive review of this innovative and ground breaking procedure. A DVD with selected videos outlines the function of the transplanted hand in the daily living activities and the professional life of these patients. This book is a milestone in medical literature and an asset for every scientific library.
"Dr. Farhat Moazam has written a wonderful book, based on her extraordinary first-hand study.... S]he is an exceptionally gifted and evocative writer. Her book not only has the attributes of a superb piece of intellectual work, but it has literary artistic merit." Renee C. Fox, Annenberg Professor Emerita of the Social Sciences at the University of Pennsylvania This is an ethnographic study of live, related kidney donation in Pakistan, based on Farhat Moazam s participant-observer research conducted at a public hospital. Her narrative is both a "thick" description of renal transplant cases and the cultural, ethical, and family conflicts that accompany them, and an object lesson in comparative bioethics."
This comprehensive, 270-page book, written by lung transplant
recipient Karen A. Couture, covers the entire transplantation
process from beginning to end for both lung and heart-lung
transplants.
More Than Six Thousand Individuals Receive Liver Transplantations Each Year. Whether You Or A Loved One Is Contemplating Liver Transplantation, On The Waiting List For Liver Transplantation, Or Are A Transplant Recipient, The Options And Information About This Surgery Can Be Overwhelming. This Invaluable Resource Offers The Guidance And Advice You Need. Written By A Prominent Physician, 100 Questions & Answers About Liver Transplantation: A Lahey Clinic Guide Gives You Authoritative, Practical Answers To Your Pre- And Post-Surgery Questions About Indications, Evaluation, Medications And Side Effects, Living Donor Transplantation, And Much More.
The popular series - A Companion to Specialist Surgical Practice - provides senior surgical trainees with a concise learning and revision source, and the practising surgeon with a regular update in a particular sub-specialty. Each volume in the series gives a current summary of the key topics within the specialty and concentrates on recent developments. As in the previous edition, evidence-based practice is indicated where appropriate - icons are used throughout the books to highlight sections of text and key references which are considered to be associated with reasonable evidence, i.e. are supported by randomized clinical trials, systematic literature reviews, meta-analysis or observational studies.
This is the true story of a man who rose from the depth of poverty to become a pioneer in modern medicine. Born in a small village in Iraq, and raised by a poor family, he met and conquered many adversities in his pursuit of a better living and his goal of becoming a physician. His chosen path was briefly derailed when he was granted a full scholarship to study engineering in United Kingdom, but he eventually came back to a successful career in medicine, becoming a leader in organ transplantation, one of the most innovative fields in modern medicine. Unfortunately, he became the victim of his own success when his achievements created animosity in his colleagues, who waged a political war and booted him to another country thousands of miles away. In his voluntary exile, he refused to be defeated and ultimately emerged stronger than ever. When forced to relocate yet again, his fame preceded him to the United States of America, where he has continued his mission to the present day. This book is a snapshot of the professional and personal life of a surgical innovator and pioneer. It is set in the background of a previous era in British, North American and international surgery. But what was his life like? How did he reach the pinnacle of success? Find out in this book.
Featuring more than 400 full-color digital intraoperative photographs, this atlas is a comprehensive "how-to" guide to heart, lung, liver, kidney, and pancreas transplantation. It presents photographs and succinct descriptions of every step of each operation--including patient positioning, dissection and exposure, retraction, anatomic details, anatomoses, completion, and drain placement. Photographs have been taken from multiple angles, including directly overhead wherever possible. Anatomic and technical variations are illustrated by drawings. Coverage includes procurement and transplantation of cadaver organs, operations to obtain organs from living donors, and transplantation of living donor organs. The liver and kidney sections include pediatric transplantation.
The organ procurement system in the United States has failed patients awaiting transplants, as evidenced by years-long waiting lists, with many patients declining in health or dying before a suitable organ donor is found. The cadaveric organ shortage can be remedied by allowing for organ purchases and sales, to encourage families of the deceased to donate the organs. This monograph is part of AEI's Evaluative Studies Series. The series aims to enhance understanding of government programs and to prompt continual review of their performance. David L. Kaserman is the Torchmark Professor and chairman of the Department of Economics at Auburn University. A. H. Barnett is a professor in, as well as the chairman of, the Department of Economics, International Studies, and Public Administration at the American University of Sharjah in the United Arab Emirates. A summary of the book follows. The first successful human organ transplant in the United States was performed on December 23, 1954, when a kidney was transplanted from a living donor who was an identical twin of the recipient. Since then, the ability to use organ transplants to save the lives and improve the health of thousands of patients suffering from kidney, heart, liver, and other organ failures has improved dramatically. New immunosuppressive drugs and advanced surgical techniques have allowed the successful use of cadaveric donor organs and, thereby, expanded the set of organs for which transplantation is a viable treatment. As a result, the number of organ transplants performed in this country has now grown to approximately 22,000 each year. Despite the tremendous successes that have been achieved, transplantation technology has failed to realize its full promise because of a chronic shortage of cadaveric organs that are made available for that use. The sad fact is that every year for the past three decades the number of cadaveric organs supplied has fallen well short of the number demanded. As a consequence, many patients are denied timely access to this life-saving treatment modality. Those who are deemed medically suitable candidates for transplantation are placed on organ waiting lists, where they often remain for one or more years before an acceptable organ becomes available. While they wait, these patients' health declines, making successful treatment increasingly problematic. Indeed, many of them die before a suitable donor organ is found. As of June 25, 2001, more than 77,000 patients were waiting for an organ transplant. Approximately 7,000 patients died in the preceding year as still more were added to the lists. And as the shortage continues, the length of the lists grows, waiting times increase, and the death toll rises. Importantly, the cadaveric organ shortage is not attributable to an inadequate number of potential organ donors. Of the 2 million or so deaths that occur in the United States each year, estimates indicate that somewhere between 13,000 and 29,000 occur under circumstances that would allow the organs of the deceased to be transplanted. Of these, only 5,843 (or 28 percent of the midrange of the estimates of the number of potential donors) yielded organ donations in 1999. Given the number of potential donors, then, organ collections could easily double or perhaps even triple without exhausting the existing potential supply. Thus, the organ shortage is the product of an ill-conceived public policy that fails to achieve higher collection rates from the available pool of donors. That policy, often referred to as the "altruistic system" of organ procurement, operates (as this name implies) entirely on the basis of unpaid donors. In the typical situation, the families of recently deceased accident or stroke victims who have been declared brain dead are asked for permission to remove the organs of the deceased for use in transplantations. Under the National Organ Transplant Act of 1984, any payment or other form of compensation to encourage the family to donate the organs is strictly proscribed by federal law. As a result, while the suppliers of all other inputs used in a transplant operation are paid market-determined prices, the parties who hold the key that makes transplantation possible cannot be paid. History of the Transplant System Notably, this system has evolved more by historical accident than conscious design. It grew out of a public policy that was intended for use with living, related kidney donors only. Because the earliest transplants were performed exclusively with kidneys donated by the recipients' living relatives, all organ transplant candidates brought the necessary donor with them when they checked into the hospital. If there was no acceptable living donor, there could be no transplant operation. As a result, there were no waiting lists and no apparent shortage. Moreover, under the living related donor system, there was no obvious need for any payment to encourage donor cooperation. The affection associated with the kinship between the donor and recipient was generally thought to be sufficient to motivate the requisite organ supply. And, where it was not, any necessary payment (or coercion) between family members could easily be arranged without resorting to the sort of middlemen generally required for market exchange. Such intrafamily cajoling by emotional pressure or outright payment also remained out of sight of the transplant centers and attending physicians. Therefore, a system of "altruistic" supply seemed to make sense in this setting, and reliance upon such a system did not seriously impede the use of this emerging medical technology. Indeed, it seemed to work quite well. That situation gradually changed, however, as new drugs began to allow the use of cadaveric donor organs and transplant success rates improved. Apparently, sometime during the 1970s, organ waiting lists began to arise as transplant candidates formed queues for needed cadaveric organs. The existing organ procurement system, however, was never altered to meet the needs of the greatly expanded pool of potential recipients created by the new technological opportunities. While some minor modifications have been implemented and considerable sums spent to educate the public regarding the virtues of organ donation, the basic system of complete reliance upon altruism to motivate supply has not changed. As a result, we have come to the current tragic situation in which thousands of patients die each year for lack of a suitable donor organ. These deaths have sparked considerable debate about how best to reform the U.S. organ procurement system to increase cadaveric donations. That debate, in turn, is reflected in a large and growing literature in which a variety of alternative policy proposals have been advanced. These proposals are surveyed in Chapter 3 of this monograph. While some authors have argued for continued reliance upon the current system with, perhaps, an appeal for increased educational expenditures, most now recognize that more fundamental policy change is required. The five most common proposals that have appeared in the literature are: (1) presumed consent, (2) conscription, (3) required request, (4) compensation, and (5) cadaveric organ markets. The first three of these proposals have, to varying degrees, been implemented either in the United States or abroad. In Chapter 3, we describe how each of these policies operates. We then demonstrate that, under reasonable assumptions regarding cadaveric organ supply and demand curves, the proposal to allow cadaveric organ markets to form clearly dominates all other policy options on social welfare grounds. Indeed, the organ market proposal appears to be the only alternative likely to eliminate the organ shortage entirely. Moreover, we estimate that, relative to the current system, creation of a market for procurement of cadaveric kidneys alone would, conservatively estimated, increase social welfare by over USD 300 million per year. Expanding the market system of procurement to other solid organs, then, would be likely to expand these welfare gains to well over USD 1 billion per year. And these welfare gains would be accompanied by several thousand lives saved annually. Despite the likelihood of such superior performance, however, the organ market proposal is not ubiquitously supported by those writing in this area. Both ethical and economic objections have been raised against the use of this most promising policy option. Upon inspection, however, these objections are found to be attributable, to a large degree, to: (1) some rather dubious ethical positions that have, in fact, been shown to be either logically weak or outright specious; (2) some fundamental misconceptions about how markets in general and organ markets in particular might operate in practice; and (3) several implicit (and empirically unlikely) assumptions regarding underlying structural parameters of cadaveric organ supply and demand curves. Chapter 4 addresses the first two sources of opposition, while Chapter 6 attempts to shed some light on the third. Importantly, we demonstrate in these chapters that none of the objections that have been raised in the literature to date is supported by either straightforward economic theory or empirical evidence. A dispassionate, objective analysis of the relevant arguments reveals no sound basis for rejecting the cadaveric organ market proposal. That is not to say, however, that sound economic reasons do not exist for particular interest groups to oppose this policy option. As with any policy change, there are parties likely to win and parties likely to lose from the formation of organ markets and resolution of the shortage. Chapter 5 focuses on the possibility that suppliers of transplant-related services - including, among other things, UNOS (an organization that maintains the nation's organ transplant waiting lists), organ procurement organizations, and transplant centers - could, in theory, suffer a decline in profits or a reduction in (or elimination of) the demand for their services if the organ market proposal were adopted. In addition, other parties providing substitutable services, such as dialysis clinics, could experience financial losses as well. While the economic stakes that a group holds in the outcome of this policy debate are not necessarily determinative of the positions adopted, they at least tend to temper each party's receptiveness to the options presented and the arguments used to support them. Consequently, while the case for adoption of the cadaveric organ market proposed is compelling, one should not expect to observe ubiquitous support for that proposal, particularly among suppliers of transplant services and organizations responsible for managing the shortage. The Case for Change The economic analysis and empirical evidence presented in this monograph support the following significant conclusions: 1. The shortage of cadaveric organs for transplantation has persisted for more than three decades. It is large, growing, and responsible for at least several thousand deaths each year. 2. The organ shortage is not caused by an insufficient number of potentially transplantable cadaveric organs. Rather, it is the direct result of a public policy that proscribes organ purchases and sales. 3. Economic theory strongly suggests that this shortage can be resolved by changing that policy to allow cadaveric organs markets to form. Such markets would permit cadaveric organ prices to rise and fall as necessary to equilibrate supply and demand, thereby eliminating the shortage. The social welfare gains achievable through implementation of the organ market proposal appear to be quite substantial, probably exceeding USD 1 billion per year. 4. Ethical objections to cadaveric organ markets appear to be either logically specious or generally unconvincing. Indeed, the alleged moral superiority of any policy that leads to unnecessary deaths along with higher expenditures must be viewed as inherently suspect. It seems, to us, indefensible to argue that one group of people should be denied lifesaving transplants simply because another group (who neither supplies nor demands cadaveric organs) prefers altruistic supply over market exchange. 5. Initial empirical evidence (though limited) suggests that adoption of organ markets would completely resolve the shortage at surprisingly low equilibrium prices. Our data suggest that payments on the order of USD 1,000 per donor would encourage an increase in the number of donors that would be sufficient to clear the market. These data also suggest that the alleged public opposition to such markets has been grossly exaggerated. It appears that it is the medical community, not the public, that is opposed to organ markets. We believe that these findings conclusively demonstrate the desirability, on social welfare grounds, of repealing the ban on cadaveric organ purchases contained in the National Organ Transplant Act of 1984. That ban has caused the unnecessary deaths of tens of thousands of patients and prolonged the suffering of many thousands more. And, ironically, it has done this while actually increasing federal and state expenditures on the affected programs. Thus, our current cadaveric organ procurement policy simultaneously causes unnecessary deaths and increased costs. And all of this is done for the high moral purpose of preventing the families of recently deceased accident and stroke victims from receiving any payment for their agreement to allow removal of their loved ones' organs.
This portable clinical handbook provides up-to-date information on ste m cell and bone marrow transplantation for nurses and other health car e professionals. The outline format and pocket size enhance the clinic al utility of this concise new reference.
The most up-to-date, comprehensive reference available in the bone mar row field. Utilizing the experience of more than twenty oncology nurse s, it addresses current challenges: to influence both ethical and admi nistrative problem solving, to help lower costs, to improve patients' understanding of problems and risks, and to participate in decision ma king for research studies. This text prepares nurses for an even large r role in the continuing application of marrow transplantation.
Sarah had been dying of cystic fibrosis since the day she was born. The disease quickly ravaged her lungs and little body bit-by-bit. Fragile and frail, she had only weeks to live, when her mum realised the reality of Sarah's situation: transplant laws, restricting access to lungs based on arbitrary age restrictions, meant Sarah's options were limited. The injustice of her daughter's fate spurred Janet to start a public battle against outdated health care regulations and a battle to save Sarah's life. Janet transformed her pain and desperation into a voice for Sarah and other kids using social media as her megaphone with friends and family as Sarah's warriors. How does a family navigate catastrophic illness and life in a hospital, while still maintaining a sense of normalcy? Saving Sarah is a story of hope and courage, and a mother's determination to never give up. It's also the story of how a family - Janet and her husband Fran have three other children, one adopted from Ghana - reacts and adjusts when one of its members is in ongoing crisis. |
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