Kidney transplantation has revolutionised the treatment of end-stage renal failure. Not only does it offer the best hope for complete rehabilitation, but it has also proved to be the most cost-effective of all treatment options, including dialysis. The surgical techniques involved have been mastered for half a century and are now considered routine. Nevertheless, this should not prevent us from appreciating the range and complexity of the issues surrounding kidney transplantation. This book examines the latest research in this field including rejection.

Three decades after the first heart transplant surgery stunned the world, organs including eyes, lungs, livers, kidneys, and hearts are transplanted every day. But despite its increasingly routine nature-or perhaps because of it-transplantation offers enormous ethical challenges. A medical ethicist who has been involved in the organ transplant debate for many years, Robert M. Veatch explores a variety of questions that continue to vex the transplantation community, offering his own solutions in many cases.

Ranging from the most fundamental questions to recently emerging issues, "Transplantation Ethics" is the first complete and systematic account of the ethical and policy controversies surrounding organ transplants. Veatch structures his discussion around three major topics: the definition of death, the procurement of organs, and the allocation of organs. He lobbies for an allocation system-administered by nonphysicians-that considers both efficiency and equity, that takes into consideration the patient's age and previous transplant history, and that operates on a national rather than a regional level.

Rich with case studies and written in an accessible style, this comprehensive reference is intended for a broad cross section of people interested in the ethics of transplantation from either the medical or public policy perspective: patients and their relatives, transplantation professionals, other health care professionals and administrators, social workers, members of organ procurement organizations, and government officials involved in the regulation of transplants.

Th is book takes an integrated, evidence-based approach the psychiatricaspects of organ transplantation. Unlike any other text currently on the market, this title presents the core principles of transplant psychiatry through an organ-based structure that includes the heart, lungs, liver, GI organs, kidney, composite tissue, and other key areas of transplantation. Each section is divided into chapters discussing psychosocial, medical, and surgical considerations prior to and post-transplant, such as indications leading to a particular type of transplantation, medical course and complications aft er transplantation, psychiatric and psychosocial considerations before and aft er transplantation, history of each type of organ transplant, and any other special considerations. Th e text ends with special topics in care, including psychopharmacology, substance abuse, psychosocial evaluation of recipients and donors, ethical considerations, cross-cultural aspects, and building the transplant psychiatry practice. It includes excellent learning tools, including over 140 tables and figures for ease of use. Written by interdisciplinary experts, Psychosocial Care of End-Stage Disease and Transplant Patients is a valuable resource for students and medical professionals interested in psychiatry, psychology, psychosomatic medicine, transplant surgery, internists, hospital administrators, pharmacists, nurses, and social workers.

This book provides an evidence based guide to the management of common kidney conditions. Concise and highly structured chapters outline a diagnosis and treatment framework for kidney diseases encountered within daily practice. Particular attention is given to the management of chronic kidney disease, genetic kidney diseases, cardiovascular complications, haemodialysis, kidney cancer, peritoneal dialysis, and kidney transplantation. Management of Kidney Disease aims to improve outcomes for patients with kidney diseases and is relevant to trainee and practising nephrologists, as well as healthcare professional treating kidney diseases. Additional questions and answers via app: Download the Springer Nature Flashcards app free of charge and use exclusive additional material to test your knowledge.

This unique book details a multidisciplinary approach for providers caring for the Mechanical Circulatory Support (MCS) patient. Authors discuss the history of MCS, patient selection, surgical and post-operative care, mobility and nutritional issues for this subgroup of patients, along with outpatient management. They are expert clinicians in the field of MCS and Extracorporeal Membrane Oxygenation (ECMO), who provide direct patient care, conduct research, publish and maintain current leadership positions within the International Society of Heart and Lung Transplant and International Consortium of Circulatory Assist Clinicians.Non-clinical issues including Regulatory, Reimbursement, Administration, Program Development and links to Professional Organizations supporting MCS Clinicians are presented in the book that will be of great value to Nurses first, but also to Advanced Practice Providers (NP/PA), Dieticians, Physical Therapists and Administrators.

The problems a transplant patient faces do not stop once the surgery is over; in addition to problems with the transplant itself, the host body reacts in a number of different ways to the arrival of a new organ and the immuno suppression required to sustain it. This pioneering text from an internationally known expert on the kidney details the problems that a patient faces with a kidney transplant and looks at how the physician can treat these; it will be an essential resource for all those involved in the initial and continuing treatment of kidney transplant patients.

This important book discusses the need for gamma irradiation in the processing of tissue allografts. With particular emphasis on tissue banking in the Asia-Pacific region, it covers a wide range of issues in tissue banking, including the basic science of radiation, quality control of the irradiation process, and clinical applications of irradiated bone grafts and amnions. A compulsory textbook for the well-regarded Singapore-based IAEA/NUS Diploma Course in Tissue Banking, it is also a useful guide for tissue bankers in establishing quality systems in their banks. Whether they be tissue banking students, tissue graft producers, radiation scientists, or transplantation surgeons, readers of this book will discover the latest developments in this exciting interdisciplinary field.

This book provides a summary of the various aspects of corneal transplantation - the clinical, experimental (including multimedia display of the surgical techniques), immunological, therapeutic and prosthetic components - in one volume. The interested specialist in one field can thus have access to information from the other fields and develop a broad concept of the challenges to be faced in achieving the ultimate goal, i.e. an optically clear, visually satisfactory, functioning corneal graft which is tolerated in the long term without the need for systemic immunosuppression. A second purpose of the book is to provide information regarding current immunological concepts of the process of corneal graft rejection. In particular, recent work in the fields of innate versus adaptive immunity, novel therapeutics and corneal xenografts is presented.

Given the tensions and demands of medicine, highly successful physicians and surgeons rarely achieve equal success as prose writers. It is truly extraordinary that a major, international pioneer in the controversial field of transplant surgery should have written a spellbinding, and heart-wrenching, autobiography. Thomas Starzl grew up in LeMars, Iowa, the son of a newspaper publisher and a nurse. His father also wrote science fiction and was acquainted with the writer Ray Bradbury. Starzl left the family business to enter Northwestern University Medical School where he earned both and M.D. and a PhD. While he was a student, and later during his surgical internship at the Johns Hopkins Hospital, he began the series of animal experiments that led eventually to the world\u2019s first transplantation of the human liver in 1963. Throughout his career, first at the University of Colorado and then at the University of Pittsburgh, he has aroused both worldwide admiration and controversy. His technical innovations and medical genius have revolutionized the field, but Starzl has not hesitated to address the moral and ethical issues raised by transplantation. In this book he clearly states his position on many hotly debated issues including brain death, randomized trials for experimental drugs, the costs of transplant operations, and the system for selecting organ recipients from among scores of desperately ill patients. There are many heroes in the story of transplantation, and many \u201cpuzzle people,\u201d the patients who, as one journalist suggested, might one day be made entirely of various transplanted parts. They are old and young, obscure and world famous. Some have been taken into the hearts of America, like Stormie Jones, the brave and beautiful child from Texas. Every patient who receives someone else\u2019s organ - and Starzl remembers each one - is a puzzle. \u201cIt was not just the acquisition of a new part,\u201d he writes. \u201cThe rest of the body had to change in many ways before the gift could be accepted. It was necessary for the mind to see the world in a different way.\u201d The surgeons and physicians who pioneered transplantation were also changed: they too became puzzle people. \u201cSome were corroded or destroyed by the experience, some were sublimated, and none remained the same.\u201d

Chest Surgery provides readers with a comprehensive and authoritative text that explains and illustrates all thoracic surgery procedures, with the exception of those on the heart and esophagus. The easy-to-read text is supported by clear, instructive line drawings and intraoperative photographs. The result is a well-illustrated practical guide for the seasoned and novice practitioner alike. The contributors, who are all acknowledged experts, demonstrate simple and safe forms of operation by distilling their experience into the most efficient methods for both standard and less common procedures. For ease in following a surgical procedure, the text description of each step is coupled with an appropriate drawing. There are often numerous ways of performing an operation, and this book takes care to impart the basic principles underlying surgery. It will be the "must-have" guide for all thoracic surgery residents who wish to acquaint themselves with the latest developments in this constantly expanding field.

The evolution of medicine is one of the outstanding features of the past century. The progress achieved by organ transplants is particularly important in this regard. Transplant medicine has progressed massively, but, due to insufficient social donation responses, waiting patient lists increase and the sad consequences of this reality persist indefinitely. This book provides a thorough analysis of the problems presented by organ transplants and social behaviour. It interprets the evolution of transplantation, and its associated medical, ethical-legal, psychosocial and religious problems, as well as educational proposals that have accompanied this medical practice over time. It will serve to provide, at all societal levels, the possibility of a clear understanding of this serious health crisis.

This reference work provides a comprehensive review of the most crucial and provocative aspects of pancreas transplantation. It represents a unique source of information and guidance for the current generation of transplant surgeons that evolved from being pure clinicians into savvy administrators knowledgeable in every regulatory aspect governing transplantation. The book contains 15 chapters covering every single aspect of the surgical operation in the donors as well as the recipients of pancreas transplants. The pre-operative workup, as well as the post-operative immunosuppression management, and the treatment of recurrent diseases are addressed in detail. In addition, the book further expands the role of islet cell transplant with its ever increasing prominence, which includes the role of autologous islet cell transplant. The impact of increasing regulatory burdens from the federal government coupled with the economic and health burden of Diabetes mellitus is discussed.

This volume is a complete manual of operative techniques for battling a severe liver injury. It provides an easy pre-operative and intra-operative reference with clear illustrations, line drawings as well as actual intra-operative color pictures, supplemented by online video segments. The early sections of the book deal with the fundamentals of surgical anatomy and critical maneuvers in the resuscitation of the patient in extremis. The various technical maneuvers for manual control of hemorrhage, debridement-resection as well as formal lobectomy of the liver, the identification of biliary tract injuries and other miscellaneous techniques, such as balloon tamponade of missile tracts, are discussed in complete detail. The book also sketches the role of liver transplantation surgeons in the acute trauma setting. The final chapters focus on the urgent problem of teaching operative techniques to young trauma surgeons in an era of dwindling surgical experience. Written by authors who are world- renowned experts in trauma management, often termed "master-surgeons", Operative Techniques for Severe Liver Injury is required preparation for all surgeons who are likely to face a massive crush injury of the liver.

This handbook is the most authoritative and up-to-date reference on spine technology written for practitioners, researchers, and students in bioengineering and clinical medicine. It is the first resource to provide a road map of both the history of the field and its future by documenting the poor clinical outcomes and failed spinal implants that contributed to problematic patient outcomes, as well as the technologies that are currently leading the way towards positive clinical outcomes. The contributors are leading authorities in the fields of engineering and clinical medicine and represent academia, industry, and international government and regulatory agencies. The chapters are split into five sections, with the first addressing clinical issues such as anatomy, pathology, oncology, trauma, diagnosis, and imaging studies. The second section, on biomechanics, delves into fixation devices, the bone implant interface, total disc replacements, injury mechanics, and more. The last three sections, on technology, are divided into materials, commercialized products, and surgery. All appropriate chapters will be continually updated and available on the publisher's website, in order to keep this important reference as up-to-date as possible in a fast-moving field.