Neglected Diseases: Extensive Space for Modern Drug Discovery provides in-depth reviews on the last progresses about neglected tropical diseases research. Topics covered in this volume include Leishmaniasis, Tripanosomiasis, Onchocerciasis and Ebolavirus infections, with insights on the future of the research on them. Part of the volume is devoted to recent contributions this field received from X-Ray crystallography.

Climate change and environmental pollution remain two primary areas of concern in today's world. These detrimental influences continue to have a strong impact on various aspects of humanity, specifically public health in tropical regions. Researchers have seen neglected tropical diseases (NTDs) affected by climate change and anthropogenic impacts. Climate Change and Anthropogenic Impacts on Neglected Tropical Diseases is a pivotal reference source that provides vital research on the association of environmental pollutants and global warming with viruses in tropical regions. While highlighting topics such as pathogenicity, travel impact, and economic impacts, this publication explores the developments and trends in these areas of medicine and ecology, as well as prevention strategies to be used for educational and sensitization purposes. This book is ideally designed for doctors, medical practitioners, ecologists, epidemiologists, environmentalists, world health organizations, researchers, biologists, policymakers, academicians, and students.

An Open Access edition of this book is available on the Liverpool University Press website and the OAPEN library. Colonialism created exclusive economic and segregatory social spaces for the exploitation and management of natural and human resources, in the form of plantations, ports, mining towns, hill stations, civil lines and new urban centres for Europeans. Contagion and Enclaves studies the social history of medicine within two intersecting enclaves in colonial India; the hill station of Darjeeling which incorporated the sanitarian and racial norms of the British Raj; and in the adjacent tea plantations of North Bengal, which produced tea for the global market. This book studies the demographic and environmental transformation of the region: the racialization of urban spaces and its contestations, establishment of hill sanatoria, expansion of tea cultivation, labour emigration and the paternalistic modes of healthcare in the plantation. It examines how the threat of epidemics and riots informed the conflictual relationship between the plantations with the adjacent agricultural villages and district towns. It reveals how Tropical Medicine was practised in its 'field'; researches in malaria, hookworm, dysentery, cholera and leprosy were informed by investigations here, and the exigencies of the colonial state, private entrepreneurship, and municipal governance subverted their implementation. Contagion and Enclaves establishes the vital link between medicine, the political economy and the social history of colonialism. It demonstrates that while enclaves were essential and distinctive sites of articulation of colonial power and economy, they were not isolated sites. The book shows that the critical aspect of the enclaves was in their interconnectedness; with other enclaves, with the global economy and international medical research.

Mathematic Modelling: Improving the Implementation, Monitoring and Evaluation of Interventions, Part B, the latest volume in the Advances in Parasitology series contains comprehensive and up-to-date reviews in the field of mathematic modeling and its implementation within parasitology. The series includes medical studies of parasites of major influence, such as Plasmodium falciparum and trypanosomes, along with reviews of more traditional areas, such as zoology, taxonomy, and life history, all of which shape current thinking and applications.

Travel health nursing has evolved as a distinct and increasingly complex specialty over the past three decades, and in 2020, ANA officially recognized travel health nursing as a nursing specialty for the first time. This first edition of ANA and ATHNA's Travel Health Nursing: Scope and Standards of Practice is an important professional resource for nurses who strive to advance the well-being of all domestic and international travellers, and the communities to which they travel and return. Travel health nurses are specially educated and trained to promote the health and safety of travellers through comprehensive risk analysis, assessment, immunizations, health education, and therapeutic interventions. Nurses in this specialty provide services in three different clinical encounters: pre-travel, during travel ("in-transit"), and post-travel in a variety of settings that include college health, occupational health, public health, the military, primary care, and nurse-managed travel health clinics, among others.

Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis.

Applications of Nanobiotechnology for Neglected Tropical Diseases describes recent advances in nanobiotechnology that can be applied to reducing the global disease burden of neglected tropical diseases (NTDs). The book explores the application of nanotechnology on the development of safe, effective, and reliable tools to prevent, diagnose, and treat NTDs. Furthermore, Applications of Nanobiotechnology for Neglected Tropical Diseases includes multidisciplinary content, combining knowledge from biochemistry, medicinal chemistry, material sciences, pharmacology, and pharmaceutics. The book is divided into three main parts, each outlining one major type of approach: (1) nano-based approaches for prevention, (2) nano-diagnostics and detection, and (3) nanotherapeutics. Each part contains chapters that delve into the different applications of the type of approach being presented in that part. A discussion of other approaches against NTD follows these three parts. This book is remarkable in its ability to encompass and thoroughly explain the latest techniques in nanobiotechnology, from basic research to patient-oriented investigation.

Cook explores the development of clinical tropical medicine from the 19th century onwards by following the pioneering doctors in this discipline, their personalities, achievements and scientific breakthroughs.

Mosquitoes, Communities, and Public Health in Texas focuses on 87 known species of mosquitoes found throughout Texas. It includes information on the ecology, medical and public health importance, and biological diversity of each species. In addition, it provides detailed identification keys for both larval and adult stages of all mosquito genera and species known to occur in Texas, along a review of surveillance and control strategies. The expansion of invasive mosquitoes from other regions (including Mexico), together with climate change occurrences increase the likelihood for an increase in diseases, such as West Nile Virus, Yellow Fever, Dengue, Chikungunya and Zika. This unique work is the first unified reference and resource rich in mosquito information for medical entomologists, mosquito and vector control professionals, pest management professionals, biologists, environmentalists, wildlife professionals, government regulators, instructors of medical entomology and public health professionals who have disease or vector responsibilities, mosquito taxonomists, epidemiologists, entomology students, academia, pest control industry, and libraries, etc., with utility for medical, veterinary and health professionals.

This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinical and veterinary practice. The book will be useful to a wide spectrum of readers: students embarking on a research career in parasitic chemotherapy, clinicians (and veterinarians) and clinical pharmacologists desiring detailed information about the drugs currently in use, and pharmaceutical technologists wanting to update their knowledge of the methods of manufacture.

This book reviews the current strategies and challenges for the treatment of bacterial, fungal, parasitic and viral infectious diseases in developing countries. Contributing authors present expert analysis on the transmission, epidemiology, bacteriology, pathogenesis and treatment of Neglected Tropical Bacterial Diseases such as Leprosy, Buruli ulcer, and Trachoma. Particular attention is also given to current antifungal agents, their spectrum of activity, mode of action, limitations, and current challenges in antifungal therapy. The authors explore the medicinal chemistry efforts that gave rise to currently launched drugs and new anti-HIV agents, and they also highlight the latest vaccine and drug developments in the clinical management of the Ebola Virus Disease, ignited by the 2014-2016 outbreak. This work has an interdisciplinary appeal and will engage scholars and professionals in the burden of communicable diseases.

Tropical Dermatology is reviewed in this issue of Dermatologic Clinics, guest edited by Drs. Scott Norton and Aisha Sethi. Drs. Norton and Sethi have gathered a panel of experts to pen articles on topics including Buruli ulcer, Outbreaks of atypical mycobacterial disease, Streptococcal pyoderma and acute rheumatic fever, Treating MRSA in the tropics, Mosquito-borne hemorrhagic fevers, Dermatologic cases at the National Zoo, Arsenical keratoses, Chagas disease, The AAD's Botswana elective, Gentian violet and similar products used to treat pyodermas, Dermatology in Mali: Leishmaniasis, Albinism in Africa, Female genital mutilation, Use of toxic skin lightening compounds, AIDS and leprosy, and Innate immunity and anti-parasitic vaccine strategies.

Natural Products in Vector-Borne Disease Management explores the potential application of natural products in vector control and disease management. The chapters discuss the global impact of specific vector-borne diseases, gaps in management, and natural products in specific stages of development - discovery, optimization, validation, and preclinical/clinical development. Toxic effects and mechanisms of action are also discussed. This book also explores how therapeutic plant derivatives can be used to combat the vectors of infection and how natural products can be used to manage and treat vector-borne diseases like malaria, leishmaniasis, dengue, and trypanosomiasis. With the inclusion of case studies on field and clinical applications and the contributions from experts in the field, Natural Products in Vector-Borne Disease Management is an essential resource to researchers, academics, and clinicians in parasitology, virology, microbiology, biotechnology, pharmacology, and pharmacognosy working in the field of vector-borne diseases.

This third edition is expanded, revised and largely re-written. However the aim remains the same and it is hoped that anyone involved in Travel or Tropical Medicine will find the contents interesting, stimulating and helpful.

As before it is divided into easy-to-read sections with clear answers that sometimes encapsulate whole diseases.

The four-part question format is retained in order to aid those intending to take Certificate or other exams in Travel Medicine. The correct answer to each question is that which is generally accepted as the best one. Nonetheless the reader may quibble with some answers and the author is always happy to accept sound advice and change accordingly.

Travel Medicine has a broad canvas. It cuts across the boundaries of Infectious Diseases, Internal Medicine, Tropical Medicine, Geographical Medicine, Aviation and Refugee Medicine. Because of this the few Textbooks we have Travel Medicine are large and difficult to digest.

This little book attempts to set down in concise form the essential elements of Travel Medicine in a way that is easy to read yet challenging.

These pages certainly invite the reader to share in excitement and wonder of this fascinating subject.

Advances in Parasitology is a series of up-to-date reviews of all areas of interest in contemporary parasitology. It includes medical studies on parasites of major influence, such as typanosomiasis and scabies, and more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications.

Mir S. Mulla joined the faculty of the Entomology Department at the University of California, Riverside in 1956, only two years after the Riverside campus was established as an independent campus within the University of California system. Prior to his appointment, Mir received his B.S. from Cornell University and then moved to the University of California, Berkeley to pursue his graduate studies. His Ph.D. from Berkeley, awarded in 1955, completed his formal American education which was the purpose of his immigration from his native Kandahar in Afghanistan. In his over 50 years at Riverside, Mir has made an incalculable impact on vector biology both within the United States and in developing countries throughout the world. Within Southern California, Mir's basic and applied research led to the rapid and sustainable control of mosquitoes and eye gnats in the Coachella Valley and so directly enabled this region to grow to the thriving, large community it is today. In 2006 his efforts in facilitating the development of the low desert of southern California were recognized through the dedication of the Mir S. Mulla Biological Control Facility by the Coachella Valley Mosquito and Vector Control District. His success has been so profound that it remains somewhat cryptic to the many who now reside in, visit, and enjoy, this region of California, oblivious to the insect problems that severely restrained development until Mir and his students ?rst applied their expertise many decades ago.

This comprehensive review provides a systematic, unbiased analysis, critique and summary of the available literature and generates novel clinical decision-making algorithms which can aid clinicians and scientists in practice management and research development. Potential mechanisms for the identified drug interactions are deduced from available preclinical and in vitro data which are interpreted in the context of the in vivo findings. Current limitations and gaps in the literature are summarized, and potential future research directions / experimentations are also suggested. In addition to the main objective to review the available clinical pharmacokinetic and pharmacodynamic drug interactions associated with WHO-recommended antimalarial drugs on the market today (i.e. chloroquine, amodiaquine, sulfadoxine, pyrimethamine, mefloquine, artemisinin, artemether, artesunate, dihydroartemisinin, artemotil, lumefantrine, primaquine, atovaquone, proguanil, piperaquine and quinine), this book also provides succinct chapter summaries on the epidemiology of malaria infection, diagnosis and therapeutics, in vivo pharmacology and chemistry, preclinical pharmacology, in vitro pharmacodynamics, in vitro reaction phenotyping, and in vitro drug-drug interaction data associated with the identified antimalarial drugs.

This book addresses the major neglected tropical diseases (NTDs) - based on their prevalence and the years of healthy life lost to disability - in Latin American and Caribbean countries. These include Chagas disease, leishmaniasis, hookworm infection, and other soil-transmitted helminth infections, followed by dengue, schistosomiasis, leishmaniasis, leprosy, cysticercosis, bartonellosis, Plasmodium vivax malaria, and onchocerciasis. Topics like disease burden, major manifestations and approaches to the control and elimination of NTDs in Latin America and the Caribbean are discussed in detail. As such, the book will be of general interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of this region of the world.