Laboratory Animal Anaesthesia, Fourth Edition provides a basic guide to anaesthesia for a very diverse audience needing content, with straight-forward, structured style of writing. Updated with effects of anaesthetics in different laboratory species, including sources of dose rates will be incorporated into tabular material. New information on pain assessment and pain management will be covered, and an increased emphasis on rats and mice for anaesthesia and perioperative care. With newly revised, full color illustrations to facilitate best learning, Laboratory animal Anesthesia, Fourth Edition provides procedures, key points and invaluable advice from a well-known and respected veterinary anesthetist and scientist with over 30 years of experience in the field.

The Second Georgia Genetics Symposium was held color. Soon after, he joined the sta? of The Jackson in September 2000, and the development of this Laboratory in Bar Harbor, Maine. book took place over the nearly 4 years that ensued. Much of Bill's research at the lab was centered During this time, many advances in the Genome around investigating phenotypic variability within Project and mouse mutagenesis were made. In the highly inbred strains, and in that connection he book overview, we discuss the development of the developed the technique of ovarian transplanta- Genome Project (which is the context for the sym- tion (even using embryonic donors) and a genetic posium), the role the mouse was playing at that scheme whereby graft compatibility could be time, how that role has evolved, and how the combined with the ability to distinguish o?spring chapters of the book address issues in mouse func- from donor and regenerated host ovaries. His tional genetics. Many of the chapters in this book work was in?uenced by the second World War, will provide useful resources for years to come. ?rst because The Jackson Laboratory turned into Of greater impact, our keynote speaker, the a production colony for the military, primarily to mutagenesis pioneer William L. (Bill) Russell, produce mice for typhoid testing, and secondly, passed away on July 23, 2003.

This book summarises the newest information on seasonal adaptation in animals. Topics include animal hibernation, daily torpor, thermoregulation, heat production, metabolic depression, biochemical adaptations, neurophysiology and energy balance. The contributors to this book present interdisciplinary research at multiple levels ranging from the molecular to the ecophysiological, as well as evolutionary approaches. The chapters of this book provide original data not published elsewhere, which makes it the most up-to-date, comprehensive source of information on these fields.

The book s subchapters correspond to presentations given at the 14th International Hibernation Symposium in August 2012 in Austria. This is a very successful series of symposia (held every four years since 1959) that attracts leading researchers in the field. Like the past symposia, this meeting and consequently the book is aimed not only at hibernation but at covering the full range of animal adaptations to seasonal environments. For the next four years, this book will serve as the cutting-edge reference work for graduate students and scientists active in this field of physiology and ecology.."

Essential Reproduction provides an accessible account of the fundamentals of reproduction within the context of cutting-edge knowledge and examples of its application. The eighth edition of this internationally best-selling title provides a multidisciplinary approach integrating anatomy, physiology, genetics, behaviour, biochemistry, molecular biology and clinical science, to give thorough coverage of the study of mammalian reproduction. Key features: Contains discussion of the latest on conceptual, informational and applied aspects of reproduction New pedagogical features such as clinical case studies at the end of each chapter Better use of boxed material to improve separation of narrative text from ancillary information Highlighted key words for ease of reference relate to summary of key points Introduction now split into two sections Expanded content in Fetal challenges, and Society and reproduction Substantial rearrangement and updating in Making sperm, Controlling fertility, and Restoring fertility

Today, veterinary science experiences major development in all its fields as a consequence of continuous technological advances in diagnostic tools and breakthrough in applied genomics and biology. This book contains 33 proceedings that were selected among those presented at the 64th Italian Veterinary Science Congress held at ASTI in 2010. It provides a timely overview of the current progress made by Italian researchers and would be of great value to anyone interested in the field of veterinary science, from animal health and care to food hygiene, and from basic to applied disciplines.

Therapeutic regimens for visceral leishmaniasis (also Kala-azar, Dum-dum fever or black fever), caused by parasitic protozoa of the Leishmania genus, evolve at a pace never seen before. Spread by tiny and abundant sand flies, the parasite infects internal organs and bone marrow and if left untreated will almost always result in the death of the host. In developing countries successful diagnosis and treatment are complicated by asymptomatic cases, undernutrition and Kala-azar/HIV co-infections. This book brings together world-renown experts writing state-of-arts review on the progress in diagnosis and treatment of visceral leishmaniasis, ultimately leading to the complete elimination of this fatal disease from South Asia. The chapters provide valuable information for disease control as well as therapy and the diagnostic improvements necessary for early treatment, subclinical detection and drug-resistant cases. The presented methods allow for points-of-care testing in the endemic area, enabling rapid detection in resource-poor settings with easy handling and low costs. This book provides essential information for scientists, medical practitioners and policy makers involved in the diagnosis, treatment and elimination of Kala-azar.

"Home-Prepared Dog and Cat Diets, Second Edition" provides an introduction to nutrition of the healthy dog and cat and an extensive discussion of medical disorders that can be managed in part through diet. Presenting easy-to-follow recipes that can be prepared at home, this new edition of Donald Strombeck's classic handbook has been completely rewritten by new author Patricia A. Schenck to reflect the latest nutritional recommendations based on current research. New chapter topics include feeding the puppy and kitten; feeding the pregnant or lactating dog or cat; feeding the senior pet; feeding the performance dog; and the role of diet in pets with cancer.

Diets are now listed together in a cookbook style for ease of use, and recipes are adjustable for any size dog or cat, allowing exact nutritional values to be calculated. Nutrient content for protein, fat, carbohydrate, and fiber have been provided for every diet, along with the nutrient density. A companion website features downloadable spreadsheets with complete nutritional breakdowns for each recipe.

Useful for both veterinarians and pet owners alike, "Home-Prepared Dog and Cat Diets, Second Edition" is a unique handbook written by an expert in the field providing an introduction to the nutritional management of dogs and cats with easy-to-use recipes for home-prepared diets.

Clarification: Calcium Carbonate

We've had some questions from readers regarding the use of the term "calcium carbonate," which is listed as an ingredient in a number of the diets found in this book, and therefore wanted to clarify what is meant by this ingredient. Baking soda comes in two forms: sodium bicarbonate and calcium carbonate. The sodium bicarbonate version is widely available as "baking soda" and is commonly used in baking, but none of the recipes in this book use it as an ingredient. The calcium carbonate version of baking soda is sometimes sold as "baking soda substitute" and sometimes referred to as simply "baking soda."

To avoid confusing sodium bicarbonate and calcium carbonate, any time the calcium carbonate type of baking soda has been used in a diet in this book, the ingredient includes the specific term "calcium carbonate." There are several manufacturers of calcium carbonate baking soda; for example, Amazon carries the Ener-G Foods product baking soda substitute. Calcium carbonate can also be sold for garden use, which is non-food-grade, so to avoid the use of the garden product in foods, the term "baking soda" was used in this book instead to indicate that readers should be sure to select a food-appropriate ingredient.

Long acting veterinary formulations play a significant role in animal health, production and reproduction within the animal health industry. Such technologies offer beneficial advantages to the veterinarian, farmer and pet owner. These advantages have resulted in them growing in popularity in recent years. The pharmaceutical scientist is faced with many challenges when innovating new products in this demanding field of controlled release. This book provides the reader with a comprehensive guide on the theories, applications, and challenges associated with the design and development of long acting veterinary formulations. The authoritative chapters of the book are written by some of the leading experts in the field. The book covers a wide scope of areas including the market influences, preformulation, biopharmaceutics, in vitro drug release testing and specification setting to name but a few. It also provides a detailed overview of the major technological advances made in this area. As a result this book covers everything a formulation scientist in industry or academia, or a student needs to know about this unique drug delivery field to advance health, production and reproduction treatment options and benefits for animals worldwide.

Presented in an easy-to-ready format, Small Animal Imaging: Self-Assessment Color Review offers a case-based approach to reviewing and interpreting images and developing a differential diagnosis when necessary. Each case begins with the patient's age, gender, breed, and species. The reason the patient was brought to the clinic is discussed along with preliminary examination and diagnostic test findings. The book Covers nearly 200 cases with supporting high-quality images for each case Provides detailed answers for each case, including radiographic findings and diagnosis Is written by well-respected experts in the field. A separate section presents detailed answers for each case including information on the radiographic findings. Also included are the radiographic diagnosis, comments, and notes on whether further imaging or evaluation is needed. This guide helps practitioners to develop a systematic approach to reviewing images. The easily-navigable text reminds practitioners of the basics in radiography and ultrasound interpretation and diagnosis, making it a quick and convenient reference.

"Manual of Trauma Management in the Dog and Cat" provides quick access to clinically relevant information on stabilizing, diagnosing, and managing the trauma patient. The book uses an outline format to provide fast access to essential information, focusing on practical advice and techniques for treating traumatic injuries. "Manual of Trauma Management in the Dog and Cat" is an ideal handbook for quickly and confidently managing this common presenting complaint.

Beginning with a concise summary of the global assessment of traumatized patients, the heart of the book is devoted to guidance on managing specific types of trauma following definitive diagnosis. "Manual of Trauma Management in the Dog and Cat" is a valuable quick-reference guide to treating canine and feline trauma patients for general practitioners and emergency specialists alike.

A sound knowledge of anatomy and physiology is an essential basis for the effective clinical treatment of companion animals. The new third edition Introduction to Veterinary Anatomy and Physiology Textbook offers clear and comprehensive of the common companion animal species. Updated throughout with a new section added on large animals, the new edition features augmented online learning resources with new questions and quizzes. Students can test their knowledge with multi-choice questions, drag and drop exercises and an image bank, while instructors can download questions, figures and exercises to use as teaching aids. An essential first purchase for all those embarking upon a veterinary career Includes augmented on-line resources with self-assessment tools and teaching aids Comprehensive coverage of all major companion animal species New large animal section added covering the cow, sheep and pig 'Applied Anatomy' tips relate theory to clinical practice, showing the relationship between anatomy and physiology and the disease process

Practical Clinical Epidemiology for the Veterinarian provides thorough coverage of the fundamentals of epidemiological concepts, situated within the context of daily clinical practice. Examines epidemiology from the lens of daily clinical practice to offer a truly practical approach Demonstrates the relevance of epidemiology to clinical problems faced in the field using practical examples to clarify the concepts Includes clinical cases from all species, with an emphasis on small animal and equine medicine, to demonstrate the concepts Uses an easy-to-read approach, with graphs, flowcharts, and tables to promote understanding Includes access to a companion website with exercises for study and review

1 Fleas are wingless insects with a laterally compressed body of about 1.5-4 mm length. Like all insects they possess six legs and three body segments. Taxonomically they belong to the order Siphonaptera (Eckert et al. 2000) (Table 1). This family contains several species and subspecies. Fleas represent one of the most important ectoparasites (Mehl- horn 2000; Mehlhorn et al. 2001b). At the moment there are more than 2000 described species and subspecies throughout the world (Borror et al. 1981). These species belong to the families Pulicidae, including Pulex spp., Ctenocephalides spp., Spilopsyllus spp. and Archaeopsyllus spp., or the familia Ceratophyllidae with the genuses Ceratophyllus or Nosopsyllus to mention only some of the most important veterinary and human representatives. Fleas have a history of about 60 million years and were already found on prehistoric mammals. While becoming parasitic the original exterior of the two-wing insects, also designated as the order Diptera, has changed by losing the wings in the adults, whereas the larval form still has similarity with the larva of the order Diptera (Strenger 1973). About 95% of the -2000 different flea species parasitize on mammals, 5% live on birds. Table 1. Taxonomy of fleas Systematic Taxonomy Phylum Arthropoda Tracheata (=Antennata) Subphylum Classis Insecta (Hexapoda) Ordo Siphonapterida Familia Pulicidae Familia CeratophyUidae Genus Ctenocephalides. Genus Ceratophyllus. Nosopsyllus Pulex.

Written by veterinarians across multiple disciplines with expertise in the canine musculoskeletal system, this book offers an easy-to-use guide for diagnosing lameness in dogs. Canine Lameness focuses on evaluation and diagnostic techniques, with descriptions of the most common reasons for lameness. Arranged by anatomical region, this approach complements the clinical assessment of a patient. Designed for ease of use, the book puts all the information needed to evaluate and diagnose a dog's orthopedic status at the reader's fingertips. Particular emphasis is placed on orthopedic examination, radiographic anatomy, and abnormal radiographic findings. Features of Canine Lameness Offers a comprehensive guide to diagnosing musculoskeletal diseases causing lameness in dogs Brings clinical examination, diagnostic imaging, and relevant musculoskeletal anatomy together into a single resource Takes a logical, regions-based approach, outlining diagnostic steps and differential diagnoses for each specific area Focuses on commonly encountered conditions while highlighting critical diagnostic steps to ensure other, less common, differential diagnoses are not missed Includes access to a companion website with video clips demonstrating detailed steps of the examination, techniques, and lameness conditions Canine Lameness is an excellent resource for veterinarians and staff involved in the diagnosis of lameness in dogs, and will be of great benefit to all animal health professionals working in the area of canine orthopedics.

Biofilms are implicated in many common medical problems including urinary tract infections, catheter infections, middle-ear infections, dental plaque, gingivitis, and some less common but more lethal processes such as endocarditis and infections in cystic fibrosis. However, the true importance of biofilms in the overall process of disease pathogenesis has only recently been recognized. Bacterial biofilms are one of the fundamental reasons for incipient wound healing failure in that they may impair natural cutaneous wound healing and reduce topical antimicrobial efficiency in infected skin wounds. Their existence explains many of the enigmas of microbial infection and a better grasp of the process may well serve to establish a different approach to infection control and management. Biofilms and their associated complications have been found to be involved in up to 80% of all infections. A large number of studies targeted at the bacterial biofilms have been conducted, and many of them are referred to in this book, which is the first of its kind. These clinical observations emphasize the importance of biofilm formation to both superficial and systemic infections, and the inability of current antimicrobial therapies to 'cure' the resulting diseases even when the in vitro tests suggest that they should be fully effective. In veterinary medicine the concept of biofilms and their role in the pathogenesis of disease has lagged seriously behind that in human medicine. This is all the more extraordinary when one considers that much of the research has been carried out using veterinary species in experimental situations. The clinical features of biofilms in human medicine is certainly mimicked in the veterinary species but there is an inherent and highly regrettable indifference to the failure of antimicrobial therapy in many veterinary disease situations, and this is probably at its most retrograde in veterinary wound management. Biofilms and Veterinary Medicine is specifically focused on discussing the concerns of biofilms to health and disease in animals and provides a definitive text for veterinary practitioners, medical and veterinary students, and researchers.

Proceedings of the XIth European Conference on Animal Blood Groups and Biochemical Polymorphism Held in Warsaw, July 2-6, 1968 Organized by European Society for Animal Blood Group Research

Completely updated and revised, Farm Animal Behaviour 2nd Edition continues to provide essential information on normal and stereotypic behaviours in a wide variety of farm animals to help in the assessment and diagnosis of their health and welfare. Comprehensive coverage of a range of farmed animals from: horses, cattle, sheep, goats and pigs through to domesticated poultry, deer, ostrich and many other species. Innate, learned and social behaviours are described together with activity, vision and hearing to build a picture of normal behaviours presented in a clear and consistent way for each species. Stereotypic behaviours, injuries and disease, resulting from improper management practices, are outlined in detail. For the second edition Professor Stefan Gunnarsson joins the author team and contributes his long-standing knowledge, clinical and scientific expertise. Many new snapshot photographs in full colour throughout have been added to further illustrate behaviours as they occur. New information on normal and stereotypic behaviours is included. The explosion in new research is captured with a wealth of new references and pointers for further reading. A consistent approach to each species allows for easy comparison. Farm Animal Behaviour 2nd Edition provides a comprehensive yet concise background for all students, postgraduates and practitioners in veterinary medicine, animal science, welfare and ethology.

"Decision Making in Small Animal Oncology" is a practical manual for the increasing number of veterinarians called upon to treat patients with cancer. This case-based quick reference leads practitioners through diagnosis, treatment, and management decisions, offering reliable guidance for more effective management of cancer care. With easy-to-follow algorithms to assist the reader through the critical thinking process, "Decision Making in Small Animal Oncology" answers the questions most commonly asked in daily practice to provide the cancer knowledge practitioners and students need in general practice.

The Fifth Chinese Peptide Symposium, hosted by Lanzhou University, was held at Lanzhou, China July 14-17, 1998, with 156 participants, including 30 scientists from abroad, representing nine countries. The four-day conference was both intense and spiritually rewarding. Our goal for CPS-98 was to provide a forum for the exchange of knowledge, cooperation and friendship between the international and Chinese scientific communities, and we believe this goal was met. The symposium consisted of 8 sessions with 42 oral and 90 poster presentations, including synthetic methods, molecular diversity and peptide libraries, structure and conformation of peptides and proteins, bioactive peptides, peptide immunology, De Novo design and synthesis of proteins and peptides, ligand-receptor interactions, the chemistry-biology-interface and challenging problems in peptides. The enthusiastic cooperation and excellent contributions were gratifying and the active response of the invited speakers contributed to the success of the symposium. The presentations were of excellent caliber and represented the most current and significant aspects of peptide science. Dr. Kit Lam of the University of Arizona and Dr. Yun-Hua Ye of Peking University were the recipients of "The Cathay Award" sponsored by the H. H. Liu Education Foundation, offered for their seminal contribution in peptide science and the Chinese Peptide Symposium. Four outstanding young scientists were selected by the organizing committee to receive awards sponsored by Haikou Nanhai Pharmaceutical Industry Co. Ltd. (Zhong He Group).

Autoimmunity is the most common cause of endocrine disorders. This volume provides an up-to-date summary of recent advances in this important field. In addition, it describes developments in our understanding of conditions such as vitiligo and pernicious anaemia which are frequently associated with autoimmune endocrinopathies. There is a detailed review of animal models of endocrine disease which have contributed greatly to current knowledge. Furthermore, the aetiology, pathogenesis and treatment of the clinical disorders are discussed in depth. The book will be of interest to anyone working in the areas of endocrinology and immunology.

A Practical Guide to Equine Radiography is designed to accompany the clinical veterinarian either within a hospital setting or out in the field. The book offers an informative step-by-step guide to obtaining high quality radiographs with a focus on image quality, accuracy, consistency and safety. General principles and equipment are covered before working through the anatomy of the horse with separate chapters devoted to each body region, providing a thorough and detailed picture of the skeletal structure of the horse, making the book an ideal reference for professionals involved with horse health and disease. Features provided in the book will guide the veterinarian through the stages of taking and interpreting normal radiographs and include: * Clinical indications of radiographic areas of interest in the horse * Equipment required * Preparation and setup guides, supported by photographs * Projections focusing on radiographic areas of interest, aided by photographs * x-rays presented with detailed labels, providing a close-up view of skeletal structures * Three dimensional images demonstrating normal anatomy A Practical Guide to Equine Radiography is an essential tool for equine practitioners, veterinary students and para-professionals.

This issue will explore the latest research and clinical information concerning endocrinology of exotic pet species. The articles will cover thyroid disease in rodent species, deslorelin implants in birds, pathology of the avian panceas, non-surgical management of ferret adrenal endocrinopathy, medical management of reproductive disorders in birds, neuroendocrine regulation of calcium metabolism in reptiles, clinical aspects of the avian hypothalamic/pituitary axis, and more!

The field of genito-urinary oncology is rapidly evolving at virtually every level. Significant advances have been made in our understanding of the molecular and cellular events which contribute to the generation of GU malignancies. At the same time, similar advances have been made in the clinical arena which have improved the diagnosis and treatment of urologic cancers. This volume attempts to summarize those advances which most impact us as clinicians, and has been divided into three sections. Section One, 'Diagnostic advances: the use of molecular medicine in the diagnosis and prognosis of GU malignancies', details how epidemiologic studies and new molecular techniques are impacting our ability to diagnose and treat GU tumors. Section Two, 'Surgical and radiation advances', details the recent major advances in the treatment of organ-confined cancers. Section Three, 'Medical advances', addresses major issues in the treatment of metastatic disease. This volume will serve as a compendium of the advances, both at the basic science and clinical levels, which are currently impacting practicing oncologists and urologists.

Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as `cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and `nutraceutical' fields, is in progress or under development. Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries. This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.