Viruses: From Understanding to Investigation provides students with a map for lifetime learning by presenting the definition and unique characteristics of viruses, including major topics, such as the virus lifecycle, structure, taxonomy, evolution, history, host-virus interactions and methods to study viruses. In addition, the book assesses the connections between, and among, the aforementioned topics, providing an integrated approach and in-depth understanding of how viruses work.

Zoonotic Viruses of Northern Eurasia: Taxonomy and Ecology provides a review of modern data of the taxonomy, distribution, and ecology of zoonotic viruses in the ecosystems of Northern Eurasia. With climate changes, increasing population density of arthropod vectors and vertebrate hosts, development of unused lands, transferences of viruses by birds, bats, infected humans, and animals, vectors allow virus populations to adapt to the new environment. This leads to the appearance of emerging or re-emerging infections. This book presents data about circulation and evolution of influenza viruses, tick-borne encephalitis virus, West Nile virus, Crimean-Congo hemorrhagic fever virus, hantaviruses, Sindbis virus, California encephalitis group viruses and other pathogenic viruses as well as of novel viruses classified for the first time using next-generation sequence.

The first review series in virology and published since 1953, "Advances in Virus Research" covers a diverse range of in-depth reviews, providing a valuable overview of the field. The series of eclectic volumes are valuable resources to virologists, microbiologists, immunologists, molecular biologists, pathologists, and plant researchers.

Volume 89 features articles on topics including plant-based vaccines, transmission of arthropod-borne viruses by mosquitoes, arboviruses in domestic and wild animals, and more.
Contributions from leading authoritiesComprehensive reviews for general and specialist useFirst and longest-running review series in virology

The seminal text "Plant Virology" is now in its fifth edition. It has been 10 years since the publication of the fourth edition, during which there has been an explosion of conceptual and factual advances. The fifth edition of "Plant Virology" updates and revises many details of the previous edition while retaining the important earlier results that constitute the field's conceptual foundation. Revamped art, along with fully updated references and increased focus on molecular biology, transgenic resistance, aphid transmission, and new, cutting-edge topics, bring the volume up to date and maintain its value as an essential reference for researchers and students in the field.
Thumbnail sketches of each genera and family groupsGenome maps of all genera for which they are knownGenetic engineered resistance strategies for virus disease controlLatest understanding of virus interactions with plants, including gene silencingInteractions between viruses and insect, fungal, and nematode vectorsContains over 300 full-color illustrations

Completely revised and updated, "Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition," delivers acontemporary and thorough review of HHV-6, beginning with foundational explorations of classification, molecular biology, and chromosomal integration of the virus, through to clinical details, including pathologic features of infection, and clinical effects on various organ systems. The work now includes coverage of HHV-7, a virus that remains underestimated in transplant reactivation, seizures, and encephalitis.

The book examines the role of HHV-6 in myriad diseases, including cognitive disorders following bone marrow transplant, mesial temporal lobe epilepsy, multiple sclerosis, autoimmune disease, encephalitis, Hodgkin's disease lymphoma (HHV-6B), and glioma (HHV-6A). Descriptions of current and novel molecular and serological diagnostic assays, along with detailed protocols, are included to aid researchers and clinicians in discriminating potential false positives originating from chromosomally integrated HHV-6, and in differentiating between active and latent infection.

"Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition" is a valuable reference for both clinical and basic scientists, including epidemiologists, virologists, practicing clinicians, infectious disease specialists, pathologists, and all scientists entering the field of herpes virus research. The work is a practical and thorough resource for a foundational understanding of HHV-6 and HHV-7, while providing a cutting-edge translational and clinical reference to those looking to understand and diagnose associated viral diseases.
Delivers the latest molecular diagnostic tests, the present-day gold standard for monitoring HHV-6
Provides expert analysis of T-cell immune response against HHV-6
Presents tools for differential diagnosis in HHV-6 viral infections
Includes new information on the previously-largely-unknown biological consequences of ciHHV-6
Offers coverage of new discoveries relating to HHV-7"

Advances in Cancer Research, Volume 142, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research.

The Aedes aegypti mosquito is a recognized vector for dengue, chikungunya, and Zika arboviruses, and has had a significant dispersion in recent years across the southern hemisphere. It is a known nuisance species in the United States and is believed to have been brought to the new world on ships used for European exploration and colonization In recent years, the use of entomopathogenic fungi has proven a promising tool for the biocontrol of Culicides that threaten public health. As such, the authors systematically review studies that evaluated the main entomopathogenic genera used in the biological control of these vectors.

The third volume in the Institute of Animal Health (IAH) Biology of Animal Infections Series, Bluetongue discusses one of the most economically important diseases of domesticated livestock. Affecting primarily sheep particularly the improved mutton and wool breeds, it is now endemic in Africa, India, the Middle and Far East, Australia and the Americas, and over the last six years has caused a series of outbreaks throughout the Mediterranean region and central Europe. Bluetongue represent a paradigm not only for the other orbiviruses (such as African horse sickness virus, which shares the same vector species) but also for other insect transmitted diseases, including those of humans.
* The only single definitive work that provides both historical and up to date data on the disease
* Describes the latest developments in epidemiological modelling, molecular epidemiology and vaccine development, as well as explaining the current global epidemiology of the disease
* Outlines the importance and possible mechanisms of overwintering, and the impact of global warming on the vectors and virus distribution

Advances in Applied Microbiology, Volume 110, the latest release in this renowned series that provides a comprehensive and authoritative review in microbiology, includes updated chapters on Multi-species biofilms for resource recovery from wastewater, Chemical imaging of biofilms with luminescent sensors, Advances in yeast fermentation biotechnology, Bacterial evasion of host defense systems, A genomic analysis on stress-responses in C. glabrata and their relevance in pathogenesis and drug resistance, and more.

Combination Therapy against Multidrug Resistance explores the potential of combination therapy as an efficient strategy to combat multi-drug resistance. Multidrug resistance (MDR) occurs when microorganisms such as bacteria, fungi, viruses, and parasites are excessively exposed to antimicrobial drugs such as antibiotics, antifungals, or antivirals, and in response the microorganism undergoes mutations or develops different resistance mechanisms to combat the drug for its survival. MDR is becoming an increasingly serious problem in both developed and developing nations. Bacterial resistance to antibiotics has developed faster than the production of new antibiotics, making bacterial infections increasingly difficult to treat, and the same is true for a variety of other diseases. Combination therapy proves to be a promising strategy as it offers potential benefits such as a broad spectrum of efficacy, greater potency than the drugs used in monotherapy, improved safety and tolerability, and reduction in the number of resistant organisms. This book considers how combination therapy can be applied in multiple situations, including cancer, HIV, tuberculosis, fungal infections, and more. Combination Therapy Against Multidrug Resistance gathers the most relevant information on the prospects of combination therapy as a strategy to combat multridrug resistance and helping to motivate the industrial sector and government agencies to invest more in research and development of this strategy as a weapon to tackle the multidrug resistance problem. It will be useful to academics and researchers involved in the development of new antimicrobial or antiinfective agents and treatment strtategies to combat multidrug resistance. Clinicians and medical nurses working in the field of infection prevention and control (IPC) will also find the book relevant

The first review series in virology and published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the field. The series of eclectic volumes are valuable resources to virologists, microbiologists, immunologists, molecular biologists, pathologists, and plant researchers. Volume 91 features articles on control of plant virus diseases.

Baculoviruses have proven to be the most powerful and versatile eukaryotic expression vectors available. This unique laboratory manual is designed to help both beginning and experienced researchers construct and use baculovirus vector systems. It simplifies selection of the most appropriate baculovirus vector design for a given problem, then describes each step of the implementation process--from vector construction to large-scale protein production. The book provides an understanding of how the vectors work; a biological overview of cells, viruses, plasmids, and promoters; guidelines for choosing optimum vectors; protocols for growing insect cells and recombinant viruses; methods of analyzing protein products and scaling up protein production; techniques for producing proteins in insect larvae; and easy-to-use maps charting available expression vectors. This comprehensive approach has many benefits for researchers and students alike. It allows them to understand how and why the vector system works and offers a rapid comparison of options for choosing the right virus, plasmid or promoter for vector design and construction, with a minimum amount of lost time. The manual is an invaluable resource for every individual engaged in the production of proteins for any purpose.

Written for advanced undergraduate students, this book is a practical, in-depth guide to plant virology. Beginning with an introduction to viruses and their classification, the text describes virus pathology, including how viruses enter and move through plant cells and induce disease. Subsequent chapters discuss how viruses spread in the field and how to measure this. Throughout, the book remains reader-friendly, using focus boxes for clear, easy-to-obtain information, enabling students to quickly access relevant information but supply sufficient detail for advanced studies. In addition to basic information on virus biology there is an additional focus on applied virology, ideal for students undertaking agricultural studies for whom study of disease and its control is essential.

Your ability to fight off infections and viruses is determined by your immune system. It may be that you fall ill more frequently than those around you. But this is not something you just have to live with - your immune resilience can be improved. Clinical nutritionist Romilly Hodges offers science-based nutritional and lifestyle advice on how to build your immune resilience. Exploring how our bodies protect us from disease, Immune Resilience will allow you to identify ways you can build your body's defences. A personalised programme covering diet, lifestyle and stress will help you achieve this. Did you know that sleep is connected to immune memory? And that good germs increase your immunity? You can even undertake exercises that boost immunity. With healthy recipes, a supplements guide and information on specific infections, Immune Resilience allows you to take control of your health.

Like other biomedical sciences, medical virology has undergone a revolution of diagnostic and scientific approaches through the advent of molecular biological techniques. Developing and maintaining an appropriate mixture of classical and molecular techniques for viral analysis is one of the challenges of medical virology today, and this volume addresses these issues. Topics covered include a broad description of "classical" techniques in viral diagnosis, nucleic acid detection by extraction and hybridization, use of the polymerase chain reaction, the application of various molecular techniques to aspects of the epidemiology of virus infections, and the principles and practical approaches to the analysis of viral evolution. The book will be of interest to students, researchers and professionals in medical virologoy, particularly hospital workers, microbiology, and molecular biology.

New antiviral drugs are urgently needed. Recent outbreaks caused by viruses with great epidemiological impact such as Zika, or extraordinary virulence such as Ebola, Nipah, Lassa, Crimean-Congo haemorrhagic fever highlight the current lack of clinically proven vaccines and treatments for these potentially catastrophic agents. Antiviral Discovery for Highly Pathogenic Emerging Viruses comprehensively outlines the state of the art in antiviral drug discovery including identification of targets, screening strategies and the current pipeline of antiviral candidates including regulatory issues. The book also addresses the challenges faced in proceeding from pre-clinical studies to animal models and clinical trials with these highly pathogenic agents. Ideal for drug discovery scientists and medicinal chemists with an interest in antiviral drug discovery and development, this book provides a complete overview of the latest progress in the field, recent advances and the challenges that remain in developing these highly pathogenic agents. Illustrated throughout with case studies this book is a valuable resource in this complex and multidisciplinary field.

A virus is not human, but the reaction to it is a measure of humanity.

America has not measured up well. Tens of thousands are dead for no reason. America is supposed to be about freedom, yet illness and fear make its citizens less free. After all, freedom is meaningless if we are too ill to think about our right to happiness or too weak to pursue it. So, if a government is making its people unhealthy it is also making them unfree.

On December 29, 2019, Timothy Snyder fell gravely ill. As he clung to life he found himself reflecting on the fragility of health, not recognized in America as a human right, but without which all rights and freedoms have no meaning. And that was before the pandemic. We have since watched understaffed and undersupplied hospitals buckling under waves of coronavirus patients. The federal government made matters worse through wilful ignorance, misinformation, and profiteering.

This passionate intervention outlines the lessons we must all learn, wherever we are, and finds glimmers of hope in dark times. Only by enshrining healthcare as a human right, elevating the authority of doctors and truth, and planning for our children's future, can everyone be properly free.

Freedom belongs to individuals. But to be free we need our health, and for our health we need one another.