As the COVID-19 pandemic has affected every corner of the world, changing our relationship to our communities, to our jobs, and to each other, the most pressing question has been-when will it end? Researchers around the globe are urgently trying to answer this question by racing to test and distribute a vaccine that could end the greatest public health threat of our time. In How to Make a Vaccine, an expert who has firsthand experience developing vaccines tells an optimistic story of how three hundred years of vaccine discovery and a century and a half of immunology research have come together at this powerful moment-and will lead to multiple COVID-19 vaccines. Dr. John Rhodes draws on his experience as an immunologist, including working alongside a young Anthony Fauci, to unravel the mystery of how vaccines are designed, tested, and produced at scale for global deployment. Concise and accessible, this book describes in everyday language how the immune system evolved to combat infection, how viruses responded by evolving ways to evade our defenses, and how vaccines do their work. That history, and the pace of current research developments, make Rhodes hopeful that multiple vaccines will protect us. Today the complex workings of the immune system are well understood. The tools needed by biomedical scientists stand ready to be used, and more than 160 vaccine candidates have already been produced. But defeating COVID-19 won't be the end of the story: Rhodes describes how discoveries today are also empowering scientists to combat future threats to global health, including a recent breakthrough in the development of genetic vaccines, which have never before been used in humans. As the world prepares for a vaccine, Rhodes offers a current and informative look at the science and strategies that deliver solutions to the crisis.

Understanding Epidemiology: Concepts, Skills, and Application teaches students the skills required to think critically about public health challenges. The text takes an interdisciplinary approach to solving epidemiological problems that mirrors epidemiology in practice. Students are exposed to the foundational principles of epidemiology and practice the application of these principles using multiple methods. Students learn to read and use public health and health science literature to design appropriate epidemiological studies, ultimately becoming intelligent consumers of health information. The third edition has been updated in light of the COVID-19 pandemic and its far-reaching effects on the field of epidemiology. The text includes new coverage of the connection between clinical medicine, biomedical research, and epidemiology and public health. Modeling, interventions, mitigation, contract tracing, quarantine, isolation, social media and communication, spillover, coordination, public health education, and evaluation are covered. Written for undergraduate students, the book does not assume a working knowledge of biostatistics. Understanding Epidemiology can be used in introductory epidemiology courses, as well as public health study design and health sciences research methods courses.

Coronavirus disease 2019 (COVID-19) is a viral infection caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). The disease was first identified in 2019 in Wuhan, China, and has since spread globally, into a dreaded pandemic. The outbreak was declared a Public Health Emergency of International Concern on 30 January 2020 by the world health organization. The disease has spread to almost 200 countries and continue to do so, resulting in huge mortalities morbidities and associated economic burden to the affected countries. The pandemic has resulted in global shut down and has impact on life of every one. This book is analyzing the epidemiology of the covid 19,characteristics of the virus,its mode of spread, pathogenesis,pathology,clinical presentation,diagnosis,prevention, and prognosis of this infection.The impact of the disease on health care system,psycho social implications and economic impact to the society are also discussed in detail.This will seve as a reference manual for treating physicians,students,epidemiologists and researchers in the field. Knowledge about the infection is fast evolving hence the readers are advised to check out the latest guidelines especially in case of management of cases of Covid19.

Population Biology of Vector-Borne Diseases is the first comprehensive survey of this rapidly developing field. The chapter topics provide an up-to-date presentation of classical concepts, reviews of emerging trends, synthesis of existing knowledge, and a prospective agenda for future research. The contributions offer authoritative and international perspectives from leading thinkers in the field. The dynamics of vector-borne diseases are far more intrinsically ecological compared with their directly transmitted equivalents. The environmental dependence of ectotherm vectors means that vector-borne pathogens are acutely sensitive to changing environmental conditions. Although perennially important vector-borne diseases such as malaria and dengue have deeply informed our understanding of vector-borne diseases, recent emerging viruses such as West Nile virus, Chikungunya virus, and Zika virus have generated new scientific questions and practical problems. The study of vector-borne disease has been a particularly rich source of ecological questions, while ecological theory has provided the conceptual tools for thinking about their evolution, transmission, and spatial extent. Population Biology of Vector-Borne Diseases is an advanced textbook suitable for graduate level students taking courses in vector biology, population ecology, evolutionary ecology, disease ecology, medical entomology, viral ecology/evolution, and parasitology, as well as providing a key reference for researchers across these fields.