This book discusses the ecology of viruses with an emphasis on the emergence of devastating hemorrhagic diseases, and a review of the molecular and cellular basis of the pathogenesis of several viral diseases. The volume provides an introduction to the mathematical analysis of recurrent epidemic viral diseases and examines the neurological and psychological diseases in relation to the pathological mechanisms underlying prion disease. Chapters explore new viral threats including HIV, bunyaviruses, morbilliviruses and caliciviruses.

Avian influenza (AI) is caused by Influenza A viruses, and are single stranded, segmented RNA viruses of the family Orthomyxoviridae. Influenza A viruses continue to pose a major threat to the poultry industry and to the public. Wild aquatic birds are considered the primary hosts of influenza A, in which the virus is enzootic. In these birds, influenza viruses usually replicate in the intestinal tract, cause no disease, and spread by fecal contamination of the water habitat. This book discusses the epidemiology, global patters, and clinical management of Avian Influenza. It also examines the symptoms, treatment and clinical outcomes of Severe Acute Respiratory Syndrome (SARS), which is a highly contagious respiratory disease caused by a SARS coronavirus.

Tim Moore completes his epic (and ill-advised) trilogy of cycling's Grand Tours. Julian Berrendero's victory in the 1941 Vuelta a Espana was an extraordinary exercise in sporting redemption: the Spanish cyclist had just spent 18 months in Franco's concentration camps, punishment for expressing Republican sympathies during the civil war. Seventy nine years later, perennially over-ambitious cyclo-adventurer Tim Moore developed a fascination with Berrendero's story, and having borrowed an old road bike with the great man's name plastered all over it, set off to retrace the 4,409km route of his 1941 triumph - in the midst of a global pandemic. What follows is a tale of brutal heat and lonely roads, of glory, humiliation, and then a bit more humiliation. Along the way Tim recounts the civil war's still-vivid tragedies, and finds the gregarious but impressively responsible locals torn between welcoming their nation's only foreign visitor, and bundling him and his filthy bike into a vat of antiviral gel.

Paperback. ISBN 978-1-912530-35-9. In this timely book, internationally renowned experts review literally every aspect of cutting edge coronavirus research providing the first coherent picture of the molecular and cellular biology since the outbreak of SARS in 2003. Essential reading for all coronavirologists as well as scientists working on other viruses of the respiratory and/or gastrointestinal tract.

'Lucid, calm, informed, directly helpful in trying to think about where we are now... The literature of the time after begins here' Evening Standard 'Taking a breather from bewildering statistics and terrible tales of contagion to read Giordano's book was a jolt of brevity and simplicity... It takes concepts that have been dancing away in our minds, just out of reach, and lines them up neatly' The Times 'Potent and original' Sunday Times 'In one short hour, in the midst of this difficult moment, Giordano reinforced my sense of hope in humanity, in the one and the many' Philippe Sands, author of East West Street and The Rat Line The Covid-19 pandemic is the most significant health emergency of our time. Writing from Italy in lockdown, physicist and novelist Paolo Giordano explains how disease spreads in our interconnected world: why it matters how it impacts us how we must react Expanding his focus to include other forms of contagion - from the environmental crisis to fake news and xenophobia - Giordano shows us not just how the coronavirus crisis got so bad so quickly, but also how we can work together to create change. Paolo Giordano is a physicist and the author of four bestselling novels. His article 'The Mathematics of Contagion' - published in Italy at the beginning of the coronavirus emergency - was shared more than 4 million times and helped shift public opinion in the early stages of the epidemic.

A virologist's insight into how viruses evolve and why global epidemics are inevitable.

In 1993 a previously healthy young man was drowning in the middle of a desert, in fluids produced by his own lungs. This was the beginning of the terrifying Sin Nombre hantavirus epidemic and the start of a scientific journey that would forever change our understanding of what it means to be human. After witnessing the Sin Nombre outbreak, Dr Frank Ryan began researching viral evolution and was astonished to discover that it's inextricable from the evolution of all life on Earth. From AIDS and Ebola to the common cold, Ryan explores the role of the virus within every ecosystem on the planet.

His gripping conclusions shed new light on the natural world, proving that what doesn't kill you really does make you (and your species) stronger.