Peptidomimetics are compounds which mimic the biological activity
of peptides while offering the advantages of increased
bioavailability, biostability, bioefficiency, and bioselectivity
against the natural biological target of the parent peptide.
Examples of peptidomimetics have been isolated as natural products,
synthesized as libraries from novel subunits, and designed on the
basis of X-ray crystallographic studies and through an intricate
knowledge of the biological mode of action of natural peptides.
They offer challenging synthetic targets and are increasingly
important medicinal agents and biological probes. As a consequence,
peptidomimetics embrace much of what is modern medicinal and
organic chemistry. This volume highlights some recent and exciting
developments in the area.
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