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Analysis of Free Radicals in Biological Systems (Paperback, 1995 ed.)
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Analysis of Free Radicals in Biological Systems (Paperback, 1995 ed.)
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"Oxidative stress" is used as the generic term describing the
involve ment of reactive oxygen species in various human diseases.
The scope of such a topic is becoming increasingly wide. The recent
interest in radicals such as nitric oxide and the discovery of new
mechanisms such as the effect of free radicals on redox sensitive
proteins and genes are enlarging our understanding of the
physiological role of free radicals. Oxidative stress is involved
in numerous pathological. processes such as ageing, respiratory or
cardiovascular diseases, cancer, neurological pathologies such as
dementia or Parkinson's disease. It still remains difficult,
however, to demonstrate by chemical measurement the in vivo
production of free radicals and even more to realise their
speciation. Therefore, the development of new tools and indicators
is engrossing many researchers working in this field. Reliable
indicators are abso lutely necessary not only to monitor the
evolution of oxidative stress in patients but also to evaluate the
efficiency of new antioxidant treat ments. The French Free radical
club of Grenoble, the CERLIB has been involved for many years in
the organisation of international training programs on methodology,
in order to provide both theoretical and practical help to
researchers from various countries. Such training sessions have
been highly successful and participants value the oppor tunity to
learn reliable techniques. This positive echo explains why the
researchers of CERLIB decided, with the help of Prof. Dr. B.
Kalyanaraman, to publish selected techniques on free radical re
search."
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