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Von Willebrand Disease - Basic and Clinical Aspects (Hardcover)
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Von Willebrand Disease - Basic and Clinical Aspects (Hardcover)
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Von Willebrand Disease: Basic and Clinical Aspects provides an
insight into all aspects of the condition. Since its discovery, von
Willebrand disease has been extensively studied and the causative
factor deficiency, the understanding of the condition and its
treatment has greatly improved. This book summarizes recent
research and will help to optimize the management of patients with
von Willebrand disease. This valuable book describes the important
and complex role of von Willebrand factor in hemostasis and
thrombosis. In addition to the current understanding of its
molecular biology, this book gives particular focus to the
association between genetic variants of von Willebrand factor and
different von Willebrand disease phenotypes. It also reviews the
important area of the obstetric and gynecological manifestations of
von Willebrand disease, as well as the treatment of acute bleeding.
Written by an international team of contributors it describes the
progress in, and difficulties of diagnosing phenotypes and
genotypes. Molecular diagnosis of type 1, type 2 and its subgroups,
and type 3 von Willebrand disease are presented as well as
discussion of the potential future role of gene therapy. Von
Willebrand Disease: Basic and Clinical Aspects is a valuable
resource for hematologists in practice and in training, and
specialists in thrombosis and hemostasis.
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