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Books > Science & Mathematics > Biology, life sciences > Biochemistry
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Calcium and Contractility - Smooth Muscle (Hardcover, 1985 ed.)
Loot Price: R2,863
Discovery Miles 28 630
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Calcium and Contractility - Smooth Muscle (Hardcover, 1985 ed.)
Series: Contemporary Biomedicine, 5
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In organizing the present volume, we had two intentions. The first
was to present the best current understanding of the mechanisms of
calcium mobilization during excitation contraction coupling of
smooth muscle at a level suited to the needs of professionals
interested in smooth muscle pharmacology and pathophysiology, while
remaining appreciable by graduate and medical students. The second
intention was to provide in sight into present-day controversies,
as well as the latest ad vances achieved by researchers in this
field. Thus, we have thor oughly discussed both the techniques and
the concepts derived from their application. An attempt has also
been made here to answer a number of profoundly important
questions: What are the mechanisms and agents responsible for the
control of contractility? What are the accompanying changes in the
state of intracellular calcium ions and the mechanisms responsible
for them? How does the regula tion of contractility occur directly
at the level of the actomyosin activity? What role do gap junctions
play in cell-to-cell coupling? What are the roles of cholinergic,
adrenergic, peptidergic, and nonadrenergic noncholinergic
interactions in calcium mobiliza tion in smooth muscle? What
changes occur in hypertension? The impact of these recent
techniques on future research is also reflected upon."
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