Written by one of the most significant contributors to the progress
of protein crystallography, this practical guide contains case
studies, a troubleshooting section and pointers on data
interpretation. It covers the theory, practice and latest
achievements in x-ray crystallography, such that any researcher in
structural biology will benefit from this extremely clearly written
book.
Part A covers the theoretical basis and such experimental
techniques as principles of x-ray diffraction, solutions for the
phase problem and time-resolved x-ray crystallography.
Part B includes case studies for different kinds of x-ray crystal
structure determination, such as the MIRAS and MAD techniques,
molecular replacement, and the difference Fourier technique.
General
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