Chemotherapy for malignant disease has brought about many rapid and
often spectacular improvements in the survival rate of some groups
of patients. Yet enthusiasm for these successes has, in part, been
offset by the problems in evaluating responses to treatment and by
the disappointment of failing to check the progress of still so
many other tumours. These reactions will be no surprise to the
medical historian but perhaps the expectations from scientific
progress nowadays sometimes demand more than can reasonably be
expected. Another expectation is that any review of chemotherapy is
com pletely up to date, even prophetic. Such is the expansion of
the subject that new drugs and trial results are continually being
reported but it is this very mass of information that creates its
own problems and makes many clinicians despair of finding a
balanced judgement on all of this information. This was the
challenge accepted by Professor Spiers. He then gathered together a
group of colleagues who are amongst the acknowledged leaders in the
field of chemotherapy for urological tumours, all of whom have made
important contributions to this subject. However, each chapter is
not merely a record of the author's experience but encompasses an
assessment of past and present practice as well as perspectives in
diagnosis and management. Almost all chapters include reference to
published work up to and including 1981."
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