This book originated in a series of cross-disciplinary
conversations in the years 1984-1990 between the editor, who is a
physician-researcher involved in clinical and laboratory research,
and a dioxin toxicologist. During the years in which the
conversations took place, an extraordinary amount of new scientific
literature was published related to dioxins, defined for purposes
of this text as the chlorinated dibenzo-p-dioxins, dibenzofurans,
polychlorinated biphe nyls (PCB's) and other compounds that are
structurally and toxicologically similar to
2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7 ,8-TCDD), the most
extensively studied and most toxic of this group of chemicals.
Dioxins also began to interest not only chemists and toxicologists,
but also specialists from diverse disciplines such as wildlife and
environmental science, immunology, neuroscience,public health,
epidemiology, med icine, government, law, sociology, and
journalism. Specialists from such varied disciplines, while
familiar with their own literature, frequently did not have time to
follow the dioxin literature outside their specialty area. In
addition, each specialty had unique knowledge, methods, and
perspectives. Cross disciplinary conversation was necessary, but
all too frequently, specialists from the various disciplines did
not speak the same language, resulting in misunderstanding.
General
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