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Books > Medicine > Clinical & internal medicine > Geriatric medicine
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Current Challenges and Management of Diseases in the Elderly Population (Hardcover)
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Current Challenges and Management of Diseases in the Elderly Population (Hardcover)
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Current Challenges and Management of Disease in the Elderly
Population is a comprehensive insight into the diseases and their
management in elderly population during ageing. The book provides
information on the development in understanding, diagnosis and
management of major diseases through biological and technological
interventions. Non-communicable diseases currently infesting old
age population will have a huge epidemiological burden on the
health care system in near future. Middle- and high-income
countries warrant sincere efforts to provide information on the
current challenges and management of disease in elderly population
in health care professionals and social organizations related to
the health of society. The book is a holistic approach by
international authors from different fields on major diseases,
which are predominantly increasing at an alarming rate in old age
population around the globe. The first chapter provides information
on stem cells involved in the regulation of cell homeostasis by
process of DNA-based methylation/demethylation and regulating gene
expression involved in cell fate to undergo apoptosis. The second
chapter emphasizes the immunological decline in innate and adaptive
immunity in ageing cells, which leads to decreased activity of
T-cell and T-regulatory cells. The third, fourth and fifth chapters
deal with chronic diseases like Type 2 Diabetes mellitus based
neuropathy, different bone diseases in old age and involvement of
Vitamin D in women's bone health in elderly population. The problem
of Type 2 Diabetes mellitus based neuropathy is the result of
unattended or poor medical interventions, therefore emphasis on
this problem and its prevention is dealt with in detail. Further
disease like osteoporosis, Paget disease, and Arthritis, which are
very common in old age population and deficiency of Vitamin D,
calcium, phosphorous in elderly women after menopause, where
estrogen based hormonal deabsorbtion of Vitamin D lead to poor bone
health, is detailed from mechanism, diagnosis, current challenges
and future perspective of preventions. Ageing eye problems and
associated challenges are incorporated with in depth information on
dry eyes and vitreous detachment, glaucoma, age-related macular
degeneration, and diabetic retinopathy, which leads to irreversible
visual impairment or blindness, the details information on
detection, treatment and prevention are discussed in Chapter 6. The
task of detecting specific diseases is paramount for the treatment
of neurodegenerative disease. Chapter 7 & 8 on biomarkers using
omics technology and metalobomics provides complete information on
the recent development in identification and analysis of
metabolites and biomolecules using different technology platforms
to detect the disease condition at an early stage. They also
highlight challenges in the field that need to be addressed to
overcome the problem of disease diagnosis for timely intervention.
The majority of neurodegenerative disorders influencing the
population above the age of 65 is mainly related to
neurodegeneration and oxidative stress. Tthe last two chapters, 9
&10, of this book have tried to provide information related to
mechanism of neurodegeneration in various neuronal disorders and
the role of various plant flavanoids in prevention of disease
onset, the effect on the choice of nutraceuticals and their role in
brain heath and prevention from old age neuronal problems.
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