46 3. 2 mRNA metabolism 47 3. 3 Initiation complex formation 3. 3.
1 Binding of initiator tRNA 47 3. 3. 2 Binding of messenger RNA 50
3. 4 Elongation 56 3. 5 Termination of protein biosynthesis and
post-translational modification 59 RNA phage protein synthesis 61
3. 6 References 63 Index 64 1 Introduction possible control
processes operating to adjust 1. 1 The problem protein synthesis to
the needs of the cells and The discovery that the genetic material
of organism. It will be assumed that the reader has living
organisms is DNA, and the later de some knowledge of molecular
biology in gen monstration that the DNA molecule is a eral and
protein biosynthesis in particular, but double helix were both
great milestones in twentieth century science, and formed the by
way of introduction each of the major molecules and stages of the
process will be foundation of the new discipline of molecular
described in simple terms, and in subsequent biology. But even
after these momentous dis chapters each will be discussed again in
coveries, the detailed mechanism by which such genetic material
could be expressed as the struc greater depth. tural and catalytic
proteins which play so im portant a role in the functioning of all
living 1. 2 Overall steps in protein biosynthesis The information
encoded in the two comple cells was still not obvious."
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