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Molecular Genetics of Inherited Eye Disorders (Hardcover)
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Molecular Genetics of Inherited Eye Disorders (Hardcover)
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"Molecular Genetics of Inherited Eye Disorders" provides an
authoritative and up-to-date account of molecular genetic advances
in a wide spectrum of genetic eye disorders, and forms the second
volume in the Modern Genetics book series. The field has produced
some dramatic and often unexpected findings in recent years ranging
from the elegant unravelling of the molecular basis of colour
vision defects to the subtle complexity of the retinoblastoma gene.
The role of crystallins in congenital cataract and of the rhodopsin
molecule in retinitis pigmentosa are discussed, illustrating the
importance of the "candidate gene" approach to genetic eye disease.
"Reverse genetic" approaches to the cloning of genes responsible
for aniridia and choroideremia exemplify the power of the new
genetic techniques and signal the start of the next experimental
phase, in which the functional characterization of identified genes
begins. Sections on albinism, retinitis pigmentosa and collagen
disorders deal w
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