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Molecular Evolution on Rugged Landscapes: Proteins, RNA and the Immune System - The Proceedings of the Workshop on Applied Molecular Evolution and the Maturation of the Immune Response, Held March, 1989 In Santa Fe, New Mexico (Paperback, New Ed)
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Molecular Evolution on Rugged Landscapes: Proteins, RNA and the Immune System - The Proceedings of the Workshop on Applied Molecular Evolution and the Maturation of the Immune Response, Held March, 1989 In Santa Fe, New Mexico (Paperback, New Ed)
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Rugged fitness landscapes, and emerging area of biological science,
underline both molecular and morphological evolution. Mathematical
descriptions of such landscapes can be expected to lead to new
experimental studies that actually test and establish their
structure. In addition, current experimental techniques now allow
one to carry out applied molecular evolution in the laboratory,
opening up the possibility of evolving biomolecules for medical and
industrial use. "Molecular Evolution on Rugged Fitness Landscapes,"
based on a Santa Fe Institute workshop, is the first book to serve
as a comprehensive introduction to these tools that permit
researchers to study the structures of complex, rugged, multipeaked
fitness landscapes.The first section of the book outlines a number
of the general issues concerning the structure of rugged fitness
landscapes. The second section examines both the history and status
of experimental work on somatic mutation and the maturation of the
immune response, and discusses the hypercycle model of the origin
of life. This proceedings volume is an excellent reference for
graduate students and professionals in immunology, population
biology, physics and molecular biology.
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