An estimated 80 million people live with a neurodegenerative
disease. That number is expected to increase rapidly as populations
age, lifespans increase, and exposure to toxins rises. Despite
decades of research and billions in funding, there are no
medications that can slow, much less stop, the progress of these
diseases. This is because diseases such as Parkinson's and
Alzheimer's do not exist in biology. Yet, hundreds of clinical
trials around the world are examining the potential of single
therapies in thousands of people sharing one of these labels.
Compounding the problem, these therapies were developed on evidence
from models that do not come close to capturing the complexity of
these diseases in the affected humans. These practices must end.
Brain Fables is a call to refocus on understanding living and aging
to create the personalized treatments each affected individual
desperately needs.
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