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Challenges in Endocrine Disruptor Toxicology and Risk Assessment (Hardcover)
Loot Price: R5,684
Discovery Miles 56 840
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Challenges in Endocrine Disruptor Toxicology and Risk Assessment (Hardcover)
Series: Issues in Toxicology, Volume 42
Expected to ship within 12 - 17 working days
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Insight into the role of hormones, particularly estrogen and
testosterone, in health and disease etiology – including
interactions with other hormone pathways – has dramatically
changed. Estrogen and androgen receptors, with their polymorphisms,
are key molecules in all tissues and are involved in a number of
homeostatic mechanisms but also pathological processes including
carcinogenesis and the development of metabolic and neurological
disorders such as diabetes and Alzheimer’s disease. Endocrine
disrupting chemicals (EDCs) can interfere with the endocrine
(hormone) systems at certain dosages and play a key role in the
pathology of disease. Most known EDCs are manmade and are therefore
an increasing concern given the number commonly found in household
products and the environment. This book will cover the mechanisms
of EDC pathology across the spectrum of disease, as well as risk
assessment and government and legal regulation to provide a
holistic view of the current issues and cutting-edge research in
the topic. With contributions from global leaders in the field,
this book will be an ideal reference for toxicologists,
endocrinologists and researchers interested in developmental
biology, regulatory toxicology and the interface between
environment and human health.
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