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Cancer Immunosurveillance - Methods and Protocols (Hardcover, 1st ed. 2019)
Loot Price: R4,323
Discovery Miles 43 230
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Cancer Immunosurveillance - Methods and Protocols (Hardcover, 1st ed. 2019)
Series: Methods in Molecular Biology, 1884
Expected to ship within 10 - 15 working days
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This volume explores the latest techniques used to study tumor
immunology. The chapters in this book detail methodologies for
functional analysis and expansion of T lymphocytes for cancer
research. The chapters also cover topics such as how single-cell
RNA-sequencing can be exploited to dissect immune cell
heterogeneity and precursors; isolating and expanding natural
killer (NK) cells; evaluating NK cell-mediated anti-tumor killing
activity in vitro; immunosurveillance orchestrated by specific
immune subsets; use of HLA peptidomics for cancer-exome based
identification of tumor neo-antigens; gold standard assessment of
immunogenic cell death in oncological mouse models and methods to
look at the therapeutic relevance of immune modulation in cancer.
Written in the highly successful Methods in Molecular Biology
series format, chapters include introductions to their respective
topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols, and tips
on troubleshooting and avoiding known pitfalls. Cutting-edge and
thorough, Cancer Immunosurveillance: Methods and Protocols is a
valuable resource to aid researchers in better understanding and
experimenting in this exciting and developing field.
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