|
Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
|
Buy Now
Multiple Testing Problems in Pharmaceutical Statistics (Paperback)
Loot Price: R1,400
Discovery Miles 14 000
|
|
|
Multiple Testing Problems in Pharmaceutical Statistics (Paperback)
Series: Chapman & Hall/CRC Biostatistics Series
Expected to ship within 12 - 17 working days
|
Useful Statistical Approaches for Addressing Multiplicity Issues
Includes practical examples from recent trials Bringing together
leading statisticians, scientists, and clinicians from the
pharmaceutical industry, academia, and regulatory agencies,
Multiple Testing Problems in Pharmaceutical Statistics explores the
rapidly growing area of multiple comparison research with an
emphasis on pharmaceutical applications. In each chapter, the
expert contributors describe important multiplicity problems
encountered in pre-clinical and clinical trial settings. The book
begins with a broad introduction from a regulatory perspective to
different types of multiplicity problems that commonly arise in
confirmatory controlled clinical trials, before giving an overview
of the concepts, principles, and procedures of multiple testing. It
then presents statistical methods for analyzing clinical dose
response studies that compare several dose levels with a control as
well as statistical methods for analyzing multiple endpoints in
clinical trials. After covering gatekeeping procedures for testing
hierarchically ordered hypotheses, the book discusses statistical
approaches for the design and analysis of adaptive designs and
related confirmatory hypothesis testing problems. The final chapter
focuses on the design of pharmacogenomic studies based on
established statistical principles. It also describes the analysis
of data collected in these studies, taking into account the
numerous multiplicity issues that occur. This volume explains how
to solve critical issues in multiple testing encountered in
pre-clinical and clinical trial applications. It presents the
necessary statistical methodology, along with examples and software
code to show how to use the methods in practice.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
You might also like..
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.
Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
