Nutrient Delivery: Nanotechnology in the Agri-Food Industry, Volume
Five, discusses the fabrication, merits, demerits, applications,
and bioavailability enhancement mechanisms of various nanodelivery
systems. Recent developments in various nanodelivery systems are
also highlighted. Volume 5 contains twenty chapters, prepared by
outstanding international researchers from Argentina, Brazil,
Canada, China, Croatia, India, Iran, Ireland, Mexico, Pakistan,
Portugal, Serbia, Sri Lanka, and the United States. In recent
years, the delivery of micronutrients at nanoscale has been widely
studied as these systems have the potential to improve
bioavailability, enable controlled release and enhance stability of
food bioactives to a greater extent. The nanodelivery systems
typically consist of the food bioactive compound encapsulated and
stabilized in food grade ingredients such as lipids, proteins or
polysaccharides with diameters ranging from 10 nm to 1000 nm. Among
these, the lipid based delivery systems such as nanoemulsions,
solid lipid nanoparticles, nanoliposomes and micelles are widely
studied for the delivery of lipophilic bioactive compounds. These
delivery vehicles improve the solubility, permeability, stability
and bioavailability of the lipophilic compounds thereby enhancing
their potential for oral delivery and functional food development.
On the other hand, the hydrophilic bioactives are delivered through
protein, polysaccharide or biopolymer based colloidal nanosystems
such as hydrogels, nanogels and polymer nanoparticles. The major
concern other than solubility is the intestinal permeability of the
micronutrients. For instance, the delivery system for compounds
with poor intestinal permeability and low solubility need to be
carefully designed using suitable lipids and surfactants.
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